PA-Lab Zhang, Qing

Research Output

2020

Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss

Liu, X., Simon, J. M., Xie, H., Hu, L., Wang, J., Zurlo, G., Fan, C., Ptacek, T. S., Herring, L., Tan, X., Li, M., Baldwin, A. S., Kim, W. Y., Wu, T., Kirschner, M. W., Gong, K. & Zhang, Q., Mar 19 2020, In : Molecular cell. 77, 6, p. 1294-1306.e5

Research output: Contribution to journalArticle

3 Scopus citations

TBK1 is a synthetic lethal target in cancer with VHL loss

Hu, L., Xie, H., Liu, X., Potjewyd, F., James, L. I., Wilkerson, E. M., Herring, L. E., Xie, L., Chen, X., Cabrera, J. C., Hong, K., Liao, C., Tan, X., Baldwin, A. S., Gong, K. & Zhang, Q., Mar 2020, In : Cancer discovery. 10, 3, p. 460-475 16 p.

Research output: Contribution to journalArticle

3 Scopus citations

The Roles of Cullin-2 E3 Ubiquitin Ligase Complex in Cancer

Liu, X., Zurlo, G. & Zhang, Q., Jan 1 2020, Advances in Experimental Medicine and Biology. Springer, p. 173-186 14 p. (Advances in Experimental Medicine and Biology; vol. 1217).

Research output: Chapter in Book/Report/Conference proceedingChapter

2019

Oxygen sensing and adaptability won the 2019 Nobel Prize in Physiology or medicine

Zhang, Q., Yan, Q., Yang, H. & Wei, W., Dec 2019, In : Genes and Diseases. 6, 4, p. 328-332 5 p.

Research output: Contribution to journalComment/debate

Open Access
3 Scopus citations

PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth

Cai, W., Su, L., Liao, L., Liu, Z. Z., Langbein, L., Dulaimi, E., Testa, J. R., Uzzo, R. G., Zhong, Z., Jiang, W., Yan, Q., Zhang, Q. & Yang, H., Dec 1 2019, In : Nature communications. 10, 1, 5800.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer

Zurlo, G., Liu, X., Takada, M., Fan, C., Simon, J. M., Ptacek, T. S., Rodriguez, J., von Kriegsheim, A., Liu, J., Locasale, J. W., Robinson, A., Zhang, J., Holler, J. M., Kim, B., Zikánová, M., Bierau, J., Xie, L., Chen, X., Li, M., Perou, C. M. & 1 others, Zhang, Q., Dec 1 2019, In : Nature communications. 10, 1, 5177.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Regulation of hypoxiainducible factor 1a during hypoxia by DAP5- induced translation of PHD2

Bryant, J. D., Brown, M. C., Dobrikov, M. I., Dobrikova, E. Y., Gemberling, S. L., Zhang, Q. & Gromeier, M., Jun 1 2018, In : Molecular and cellular biology. 38, 11, e00647-17.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2017

FBW7 loss promotes chromosomal instability and tumorigenesis via cyclin E1/CDK2–mediated phosphorylation of CENP-A

Takada, M., Zhang, W., Suzuki, A., Kuroda, T. S., Yu, Z., Inuzuka, H., Gao, D., Wan, L., Zhuang, M., Hu, L., Zhai, B., Fry, C. J., Bloom, K., Li, G., Karpen, G. H., Wei, W. & Zhang, Q., Sep 15 2017, In : Cancer research. 77, 18, p. 4881-4893 13 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations
2015

EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer

Zhang, J., Wang, C., Chen, X., Takada, M., Fan, C., Zheng, X., Wen, H., Liu, Y., Wang, C., Pestell, R. G., Aird, K. M., Kaelin, W. G., Liu, X. S. & Zhang, Q., Dec 2 2015, In : EMBO Journal. 34, 23, p. 2953-2970 18 p.

Research output: Contribution to journalArticle

25 Scopus citations
2011

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

Lin, W., Cao, J., Liu, J., Beshiri, M. L., Fujiwara, Y., Francis, J., Cherniack, A. D., Geisen, C., Blair, L. P., Zou, M. R., Shen, X., Kawamori, D., Liu, Z., Grisanzio, C., Watanabe, H., Minamishima, Y. A., Zhang, Q., Kulkarni, R. N., Signoretti, S., Rodig, S. J. & 7 others, Bronson, R. T., Orkin, S. H., Tuck, D. P., Benevolenskaya, E. V., Meyerson, M., Kaelin, W. G. & Yan, Q., Aug 16 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 33, p. 13379-13386 8 p.

Research output: Contribution to journalArticle

Open Access
93 Scopus citations
2008

Autocrine and paracrine chemokine receptor 7 activation in head and neck cancer: Implications for therapy

Wang, J., Seethala, R. R., Zhang, Q., Gooding, W., Van Waes, C., Hasegawa, H. & Ferris, R. L., Apr 2008, In : Journal of the National Cancer Institute. 100, 7, p. 502-512 11 p.

Research output: Contribution to journalArticle

Open Access
55 Scopus citations

Immunohistochemical analysis of phosphotyrosine signal transducer and activator of transcription 3 and epidermal growth factor receptor autocrine signaling pathways in head and neck cancers and metastatic lymph nodes

Seethala, R. R., Gooding, W. E., Handler, P. N., Collins, B., Zhang, Q., Siegfried, J. M. & Grandis, J. R., Mar 1 2008, In : Clinical Cancer Research. 14, 5, p. 1303-1309 7 p.

Research output: Contribution to journalReview article

Open Access
37 Scopus citations
2007

Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer

Zhang, Q., Bhola, N. E., Lui, V. W. Y., Siwak, D. R., Thomas, S. M., Gubish, C. T., Siegfried, J. M., Mills, G. B., Shin, D. & Grandis, J. R., Apr 1 2007, In : Molecular Cancer Therapeutics. 6, 4, p. 1414-1424 11 p.

Research output: Contribution to journalArticle

Open Access
66 Scopus citations