Pharmacology - Albanesi Lab

Research Output 1968 2019

2019

Myristoylation-Dependent Palmitoylation of the Receptor Tyrosine Kinase Adaptor FRS2α

Barylko, B., Chen, Y. J., Hennen, J., Angert, I., Chen, Y., Mueller, J. D., Sun, H. Q., Taylor, C. A., Liou, J., Yin, H. & Albanesi, J. P., Jun 25 2019, In : Biochemistry. 58, 25, p. 2809-2813 5 p.

Research output: Contribution to journalArticle

Lipoylation
Receptor Protein-Tyrosine Kinases
Fibroblast Growth Factor Receptors
Substrates
Tyrosine
2018
2 Citations (Scopus)

Comobility of GABARAP and Phosphatidylinositol 4-Kinase 2A on Cytoplasmic Vesicles

Chen, Y., Sun, H. Q., Eichorst, J. P., Albanesi, J. P., Yin, H. & Mueller, J. D., Jul 3 2018, In : Biochemistry. 57, 26, p. 3556-3559 4 p.

Research output: Contribution to journalArticle

Cytoplasmic Vesicles
1-Phosphatidylinositol 4-Kinase
Cell membranes
Fusion reactions
Monomers
6 Citations (Scopus)

Palmitoylation and Membrane Binding of Arc/Arg3.1: A Potential Role in Synaptic Depression

Barylko, B., Wilkerson, J. R., Cavalier, S. H., Binns, D. D., James, N. G., Jameson, D. M., Huber, K. M. & Albanesi, J. P., Feb 6 2018, In : Biochemistry. 57, 5, p. 520-524 5 p.

Research output: Contribution to journalArticle

Lipoylation
Neuronal Plasticity
Cysteine
MEF2 Transcription Factors
Depression
2017
8 Citations (Scopus)
Long-Term Synaptic Depression
Metabotropic Glutamate Receptors
Synapses
Health
Metabotropic Glutamate 5 Receptor
2016
3 Citations (Scopus)

Association of Endophilin B1 with Cytoplasmic Vesicles

Li, J., Barylko, B., Eichorst, J. P., Mueller, J. D., Albanesi, J. P. & Chen, Y., Aug 9 2016, In : Biophysical Journal. 111, 3, p. 565-576 12 p.

Research output: Contribution to journalArticle

Dynamin II
Cytoplasmic Vesicles
Transport Vesicles
varespladib methyl
Caveolins
2015
19 Citations (Scopus)

Enhancement of dynamin polymerization and GTPase activity by Arc/Arg3.1

Byers, C. E., Barylko, B., Ross, J. A., Southworth, D. R., James, N. G., Taylor, C. A., Wang, L., Collins, K. A., Estrada, A., Waung, M., Tassin, T. C., Huber, K. M., Jameson, D. M. & Albanesi, J. P., Jun 1 2015, In : Biochimica et Biophysica Acta - General Subjects. 1850, 6, p. 1310-1318 9 p.

Research output: Contribution to journalArticle

Dynamin II
Dynamins
GTP Phosphohydrolases
Polymerization
Endocytosis
14 Citations (Scopus)
Protein Transport
GABA-A Receptors
Lysosomes
Phosphatidylinositols
Phosphatidylinositol 4,5-Diphosphate
62 Citations (Scopus)

GABARAPs regulate PI4P-dependent autophagosome: Lysosome fusion

Wang, H., Sun, H. Q., Zhu, X., Zhang, L., Albanesi, J., Levine, B. & Yin, H., Jun 2 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 22, p. 7015-7020 6 p.

Research output: Contribution to journalArticle

Lysosomes
Autophagy
Phosphotransferases
Phosphatidylinositol 4,5-Diphosphate
Aminobutyrates
2014
9 Citations (Scopus)

A mutation associated with centronuclear myopathy enhances the size and stability of dynamin 2 complexes in cells

James, N. G., Digman, M. A., Ross, J. A., Barylko, B., Wang, L., Li, J., Chen, Y., Mueller, J. D., Gratton, E., Albanesi, J. P. & Jameson, D. M., 2014, In : Biochimica et Biophysica Acta - General Subjects. 1840, 1, p. 315-321 7 p.

Research output: Contribution to journalArticle

Dynamin II
Congenital Structural Myopathies
Mutation
Fluorescence
Fluorescence Spectrometry
2013
8 Citations (Scopus)

Fluorescence fluctuation spectroscopy approaches to the study of receptors in live cells

Jameson, D. M., James, N. G. & Albanesi, J. P., 2013, Methods in Enzymology. Vol. 519. p. 87-113 27 p. (Methods in Enzymology; vol. 519).

Research output: Chapter in Book/Report/Conference proceedingChapter

Fluorescence Spectrometry
Fluorescence
Spectroscopy
Cell Surface Receptors
Cell Communication
23 Citations (Scopus)

Off-target effects of MEK inhibitors

Wauson, E. M., Guerra, M. L., Barylko, B., Albanesi, J. P. & Cobb, M. H., Aug 6 2013, In : Biochemistry. 52, 31, p. 5164-5166 3 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Chromaffin Cells
Mitogen-Activated Protein Kinase 1
Transcription
Mitogen-Activated Protein Kinases
2012
7 Citations (Scopus)

Molecular brightness analysis reveals phosphatidylinositol 4-kinase IIβ association with clathrin-coated vesicles in living cells

Li, J., Barylko, B., Johnson, J., Mueller, J. D., Albanesi, J. P. & Chen, Y., Oct 17 2012, In : Biophysical Journal. 103, 8, p. 1657-1665 9 p.

Research output: Contribution to journalArticle

Clathrin-Coated Vesicles
1-Phosphatidylinositol 4-Kinase
Endocytosis
Phosphatidylinositols
Clathrin Light Chains
38 Citations (Scopus)

Number and brightness analysis of LRRK2 oligomerization in live cells

James, N. G., Digman, M. A., Gratton, E., Barylko, B., Ding, X., Albanesi, J. P., Goldberg, M. S. & Jameson, D. M., Jun 6 2012, In : Biophysical Journal. 102, 11

Research output: Contribution to journalArticle

Leucine
Phosphotransferases
Parkinson Disease
Cytosol
Cell Membrane
48 Citations (Scopus)

Phosphatidylinositol 4-kinase IIα is palmitoylated by golgi-localized palmitoyltransferases in cholesterol-dependent manner

Lu, D., Sun, H. Q., Wang, H., Barylko, B., Fukata, Y., Fukata, M., Albanesi, J. P. & Yin, H. L., Jun 22 2012, In : Journal of Biological Chemistry. 287, 26, p. 21856-21865 10 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Cholesterol
Lipoylation
Association reactions
Membranes
40 Citations (Scopus)

Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila

Burgess, J., Del Bel, L. M., Ma, C. I. J., Barylko, B., Polevoy, G., Rollins, J., Albanesi, J. P., Krämer, H. & Brill, J. A., Aug 15 2012, In : Development (Cambridge). 139, 16, p. 3040-3050 11 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Endosomes
Secretory Vesicles
Adhesives
trans-Golgi Network

Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila

Burgess, J., Del Bel, L. M., Ma, C. I. J., Barylko, B., Polevoy, G., Rollins, J., Albanesi, J. P., Krämer, H. & Brill, J. A., Aug 15 2012, In : Journal of Cell Science. 125, 16, p. 3040-3050 11 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Endosomes
Secretory Vesicles
Adhesives
trans-Golgi Network
2011
22 Citations (Scopus)

Dimeric endophilin A2 stimulates assembly and GTPase activity of dynamin 2

Ross, J. A., Chen, Y., Müller, J., Barylko, B., Wang, L., Banks, H. B., Albanesi, J. P. & Jameson, D. M., Feb 2 2011, In : Biophysical Journal. 100, 3, p. 729-737 9 p.

Research output: Contribution to journalArticle

Dynamin II
Dynamins
GTP Phosphohydrolases
varespladib methyl
Endocytosis
25 Citations (Scopus)

Oligomerization state of dynamin 2 in cell membranes using TIRF and number and brightness analysis

Ross, J. A., Digman, M. A., Wang, L., Gratton, E., Albanesi, J. P. & Jameson, D. M., Feb 2 2011, In : Biophysical Journal. 100, 3

Research output: Contribution to journalArticle

Dynamin II
Cell Membrane
Membranes
Dynamins
GTP Phosphohydrolases
18 Citations (Scopus)

Stabilization of phosphatidylinositol 4-kinase type IIβ by interaction with Hsp90

Jung, G., Barylko, B., Lu, D., Shu, H., Yin, H. & Albanesi, J. P., Apr 8 2011, In : Journal of Biological Chemistry. 286, 14, p. 12775-12784 10 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Stabilization
Membranes
Cytosol
Phosphotransferases
45 Citations (Scopus)

The CD3 ζ subunit contains a phosphoinositide-binding motif that is required for the stable accumulation of TCR-CD3 complex at the immunological synapse

DeFord-Watts, L. M., Dougall, D. S., Belkaya, S., Johnson, B. A., Eitson, J. L., Roybal, K. T., Barylko, B., Albanesi, J. P., Wülfing, C. & Van Oers, N. S. C., Jun 15 2011, In : Journal of Immunology. 186, 12, p. 6839-6847 9 p.

Research output: Contribution to journalArticle

T-Cell Antigen Receptor-CD3 Complex
Immunological Synapses
Phosphatidylinositols
T-Lymphocytes
CD3 Antigens
2010
77 Citations (Scopus)
Dynamins
Synaptic Vesicles
Synaptic Transmission
Synapses
Population
13 Citations (Scopus)

CNP/GC-B system: A new regulator of adipogenesis

Katafuchi, T., Garbers, D. L. & Albanesi, J. P., Oct 2010, In : Peptides. 31, 10, p. 1906-1911 6 p.

Research output: Contribution to journalArticle

C-Type Natriuretic Peptide
Adipogenesis
Xanthine
Guanylate Cyclase
Dexamethasone
35 Citations (Scopus)

Dynamin 2 mutants linked to centronuclear myopathies form abnormally stable polymers

Wang, L., Barylko, B., Byers, C., Ross, J. A., Jameson, D. M. & Albanesi, J. P., Jul 23 2010, In : Journal of Biological Chemistry. 285, 30, p. 22753-22757 5 p.

Research output: Contribution to journalArticle

Dynamin II
Congenital Structural Myopathies
Dynamins
Polymers
GTP Phosphohydrolases
10 Citations (Scopus)

The proline/arginine-rich domain is a major determinant of dynamin self-activation

Barylko, B., Wang, L., Binns, D. D., Ross, J. A., Tassin, T. C., Collins, K. A., Jameson, D. M. & Albanesi, J. P., Dec 21 2010, In : Biochemistry. 49, 50, p. 10592-10594 3 p.

Research output: Contribution to journalArticle

Dynamin I
Dynamins
Dynamin II
Proline
Dynamin III
2009
28 Citations (Scopus)

Fluorescence fluctuation spectroscopy: Ushering in a new age of enlightenment for cellular dynamics

Jameson, D. M., Ross, J. A. & Albanesi, J. P., 2009, In : Biophysical Reviews. 1, 3, p. 105-118 14 p.

Research output: Contribution to journalArticle

Fluorescence Spectrometry
Physical Chemistry
Physics
Photons
Cell Biology
49 Citations (Scopus)

Palmitoylation controls the catalytic activity and subcellular distribution of phosphatidylinositol 4-kinase IIα

Barylko, B., Mao, Y. S., Wlodarski, P., Jung, G., Binns, D. D., Sun, H. Q., Yin, H. L. & Albanesi, J. P., Apr 10 2009, In : Journal of Biological Chemistry. 284, 15, p. 9994-10003 10 p.

Research output: Contribution to journalArticle

Lipoylation
1-Phosphatidylinositol 4-Kinase
Catalyst activity
Membranes
Cysteine
134 Citations (Scopus)

Regulation of the proteasome by neuronal activity and calcium/calmodulin-dependent protein kinase II

Djakovic, S. N., Schwarz, L. A., Barylko, B., DeMartino, G. N. & Patrick, G. N., Sep 25 2009, In : Journal of Biological Chemistry. 284, 39, p. 26655-26665 11 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Calcium-Calmodulin-Dependent Protein Kinases
Proteasome Endopeptidase Complex
Ubiquitin
Proteolysis
50 Citations (Scopus)

The cytoplasmic tail of the T cell receptor CD3 ε subunit contains a phospholipid-binding motif that regulates T cell functions

DeFord-Watts, L. M., Tassin, T. C., Becker, A. M., Medeiros, J. J., Albanesi, J. P., Love, P. E., Wülfing, C. & Van Oers, N. S. C., Jul 15 2009, In : Journal of Immunology. 183, 2, p. 1055-1064 10 p.

Research output: Contribution to journalArticle

T-Cell Antigen Receptor
Tail
Phospholipids
T-Lymphocytes
T-Cell Antigen Receptor-CD3 Complex
2008
27 Citations (Scopus)

Molecular determinants of activation and membrane targeting of phosphoinositol 4-kinase IIβ

Jung, G., Wang, J., Wlodarski, P., Barylko, B., Binns, D. D., Shu, H., Yin, H. L. & Albanesi, J. P., Jan 15 2008, In : Biochemical Journal. 409, 2, p. 501-509 9 p.

Research output: Contribution to journalArticle

Phosphotransferases
Chemical activation
Membranes
Lipoylation
Catalytic Domain
2007
40 Citations (Scopus)

Dual control of cardiac Na+-Ca2+ exchange by PIP2: Electrophysiological analysis of direct and indirect mechanisms

Yaradanakul, A., Feng, S., Shen, C., Lariccia, V., Lin, M. J., Yang, J., Dong, P., Yin, H. L., Albanesi, J. P. & Hilgemann, D. W., Aug 1 2007, In : Journal of Physiology. 582, 3, p. 991-1010 20 p.

Research output: Contribution to journalArticle

Membranes
Phosphatidylinositols
Cytoskeleton
Phosphotransferases
Adenylyl Imidodiphosphate
29 Citations (Scopus)

Phosphatidylinositol 4-kinase III-β is required for Golgi maintenance and cytokinesis in Trypanosoma brucei

Rodgers, M. J., Albanesi, J. P. & Phillips, M. A., Jul 2007, In : Eukaryotic Cell. 6, 7, p. 1108-1118 11 p.

Research output: Contribution to journalArticle

1-phosphatidylinositol 4-kinase
Trypanosoma brucei
Trypanosoma brucei brucei
1-Phosphatidylinositol 4-Kinase
Cytokinesis
2006
89 Citations (Scopus)

Membrane guanylyl cyclase receptors: an update

Garbers, D. L., Chrisman, T. D., Wiegn, P., Katafuchi, T., Albanesi, J. P., Bielinski, V., Barylko, B., Redfield, M. M. & Burnett, J. C., Aug 2006, In : Trends in Endocrinology and Metabolism. 17, 6, p. 251-258 8 p.

Research output: Contribution to journalArticle

Guanylate Cyclase-Coupled Receptors
Blood Volume
Hypertrophy
Intestines
Hyperplasia
2005
32 Citations (Scopus)

Structure, function, and regulation of myosin 1C

Barylko, B., Jung, G. & Albanesi, J. P., 2005, In : Acta Biochimica Polonica. 52, 2, p. 373-380 8 p.

Research output: Contribution to journalArticle

Myosins
Tail
Neck
Calmodulin
Lipids
2003
381 Citations (Scopus)

Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi

Wang, Y. J., Wang, J., Sun, H. Q., Martinez, M., Sun, Y. X., Macia, E., Kirchhausen, T., Albanesi, J. P., Roth, M. G. & Yin, H. L., Aug 8 2003, In : Cell. 114, 3, p. 299-310 12 p.

Research output: Contribution to journalArticle

Vesicular Transport Adaptor Proteins
Transcription Factor AP-1
Golgi Apparatus
RNA Interference
RNA
30 Citations (Scopus)

Saccharomyces cerevisiae contains a Type II phosphoinositide 4-kinase

Shelton, S. N., Barylko, B., Binns, D. D., Horazdovsky, B. F., Albanesi, J. P. & Goodman, J. M., Apr 15 2003, In : Biochemical Journal. 371, 2, p. 533-540 8 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
Yeast
Saccharomyces cerevisiae
Phosphotransferases
2002

Activation of dynamin II by POPC in giant unilamellar vesicles: A two-photon fluorescence microscopy study

Bagatolli, L. A., Binns, D. D., Jameson, D. M. & Albanesi, J. P., 2002, In : Protein Journal. 21, 6, p. 383-391 9 p.

Research output: Contribution to journalArticle

Dynamin II
Unilamellar Liposomes
Phosphorylcholine
Fluorescence microscopy
Photons
6 Citations (Scopus)

Activation of dynamin II by POPC in giant unilamellar vesicles: A two-photon fluorescence microscopy study

Bagatolli, L. A., Binns, D. D., Jameson, D. M. & Albanesi, J. P., Aug 2002, In : Journal of Protein Chemistry. 21, 6, p. 383-391 9 p.

Research output: Contribution to journalArticle

Dynamin II
Unilamellar Liposomes
Phosphorylcholine
Fluorescence microscopy
Photons
33 Citations (Scopus)

Analysis of the catalytic domain of phosphatidylinositol 4-kinase type II

Barylko, B., Wlodarski, P., Binns, D. D., Gerber, S. H., Earnest, S., Sudhof, T. C., Grichine, N. & Albanesi, J. P., Nov 15 2002, In : Journal of Biological Chemistry. 277, 46, p. 44366-44375 10 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Catalytic Domain
Phosphotransferases
Phosphatidylinositols
Drosophila
108 Citations (Scopus)

Mechanism of caveolin filament assembly

Fernandez, I., Ying, Y., Albanesi, J. & Anderson, R. G. W., Aug 20 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 17, p. 11193-11198 6 p.

Research output: Contribution to journalArticle

Caveolins
Caveolin 1
Caveolae
Ultracentrifugation
Circular Dichroism
159 Citations (Scopus)

Membrane fusion: Stalk model revisited

Markin, V. S. & Albanesi, J. P., 2002, In : Biophysical Journal. 82, 2, p. 693-712 20 p.

Research output: Contribution to journalArticle

Membrane Fusion
Phase Transition
Membrane Lipids
99 Citations (Scopus)
Phosphatidylinositol Phosphates
High performance liquid chromatography
Anions
Phospholipids
High Pressure Liquid Chromatography
28 Citations (Scopus)

Oligomerization and kinetic mechanism of the dynamin GTPase

Eccleston, J. F., Binns, D. D., Davis, C. T., Albanesi, J. P. & Jameson, D. M., Jul 2002, In : European Biophysics Journal. 31, 4, p. 275-282 8 p.

Research output: Contribution to journalArticle

Dynamins
GTP Phosphohydrolases
Endocytosis
Osmolar Concentration
Biological Phenomena
99 Citations (Scopus)

Type II phosphatidylinositol 4-kinase β is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP

Wei, Y. J., Sun, H. Q., Yamamoto, M., Wlodarski, P., Kunii, K., Martinez, M., Barylko, B., Albanesi, J. P. & Yin, H. L., Nov 29 2002, In : Journal of Biological Chemistry. 277, 48, p. 46586-46593 8 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Cell membranes
Guanosine Triphosphate
Membrane Proteins
Cell Membrane
2001
15 Citations (Scopus)

Activation of dynamin GTPase activity by phosphoinositides and SH3 domain-containing proteins

Barylko, B., Binns, D. D. & Albanesi, J. P., 2001, In : Methods in Enzymology. 329, p. 486-496 11 p.

Research output: Contribution to journalArticle

Dynamins
src Homology Domains
GTP Phosphohydrolases
Phosphatidylinositols
Proteins
138 Citations (Scopus)

A Novel Family of Phosphatidylinositol 4-Kinases Conserved from Yeast to Humans

Barylko, B., Gerber, S. H., Binns, D. D., Grichine, N., Khvotchev, M., Südhof, T. C. & Albanesi, J. P., Mar 16 2001, In : Journal of Biological Chemistry. 276, 11, p. 7705-7708 4 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
Yeast
Yeasts
Phosphotransferases
55 Citations (Scopus)

Myosin-I nomenclature

Gillespie, P. G., Albanesi, J. P., Bähler, M., Bement, W. M., Berg, J. S., Burgess, D. R., Burnside, B., Cheney, R. E., Corey, D. P., Coudrier, E., De Lanerolle, P., Hammer, J. A., Hasson, T., Holt, J. R., Hudspeth, A. J., Ikebe, M., Kendrick-Jones, J., Korn, E. D., Li, R., Mercer, J. A. & 8 others, Milligan, R. A., Mooseker, M. S., Michael Ostap, E., Petit, C., Pollard, T. D., Sellers, J. R., Soldati, T. & Titus, M. A., Nov 26 2001, In : Journal of Cell Biology. 155, 5, p. 703-704 2 p.

Research output: Contribution to journalArticle

Myosin Type I
Terminology
Names
Human Genome
Vertebrates
2000
140 Citations (Scopus)

Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity

Claing, A., Perry, S. J., Achiriloaie, M., Walker, J. K. L., Albanesi, J. P., Lefkowitz, R. J. & Premont, R. T., Feb 1 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 3, p. 1119-1124 6 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
Clathrin
GTP-Binding Proteins
G-Protein-Coupled Receptor Kinases
ADP-Ribosylation Factors
46 Citations (Scopus)

Regulation of the enzymatic and motor activities of myosin I

Barylko, B., Binns, D. D. & Albanesi, J. P., Mar 17 2000, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1496, 1, p. 23-35 13 p.

Research output: Contribution to journalArticle

Myosin Type I
Motor Activity
Myosins
Ion Channel Gating
Organelles
71 Citations (Scopus)

SCAMP1 function in endocytosis

Fernández-Chacón, R., Achiriloaie, M., Janz, R., Albanesi, J. P. & Südhof, T. C., Apr 28 2000, In : Journal of Biological Chemistry. 275, 17, p. 12752-12756 5 p.

Research output: Contribution to journalArticle

Cell membranes
Endocytosis
Golgi Apparatus
Cell Membrane
Carrier Proteins
40 Citations (Scopus)

The mechanism of GTP hydrolysis by Dynamin II: A transient kinetic study

Binns, D. D., Helms, M. K., Barylko, B., Davis, C. T., Jameson, D. M., Albanesi, J. P. & Eccleston, J. F., Jun 20 2000, In : Biochemistry. 39, 24, p. 7188-7196 9 p.

Research output: Contribution to journalArticle

Dynamin II
Dynamins
Guanosine Triphosphate
Hydrolysis
Kinetics