Pharmacology - Cobb Lab

Research Output

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Review article
2018

WNK pathways in cancer signaling networks 06 Biological Sciences 0601 Biochemistry and Cell Biology

Gallolu Kankanamalage, S., Karra, A. S. & Cobb, M. H., Nov 3 2018, In : Cell Communication and Signaling. 16, 1, 72.

Research output: Contribution to journalReview article

7 Scopus citations
2016

Hypertension: The missing WNKs

Dbouk, H. A., Huang, C. L. & Cobb, M. H., Jul 1 2016, In : American Journal of Physiology - Renal Physiology. 311, 1, p. F16-F27

Research output: Contribution to journalReview article

7 Scopus citations

Small cell lung cancer: Can recent advances in biology and molecular biology be translated into improved outcomes?

Bunn, P. A., Minna, J. D., Augustyn, A., Gazdar, A. F., Ouadah, Y., Krasnow, M. A., Berns, A., Brambilla, E., Rekhtman, N., Massion, P. P., Niederst, M., Peifer, M., Yokota, J., Govindan, R., Poirier, J. T., Byers, L. A., Wynes, M. W., McFadden, D. G., MacPherson, D., Hann, C. L. & 34 others, Farago, A. F., Dive, C., Teicher, B. A., Peacock, C. D., Johnson, J. E., Cobb, M. H., Wendel, H. G., Spigel, D., Sage, J., Yang, P., Pietanza, M. C., Krug, L. M., Heymach, J., Ujhazy, P., Zhou, C., Goto, K., Dowlati, A., Christensen, C. L., Park, K., Einhorn, L. H., Edelman, M. J., Giaccone, G., Gerber, D. E., Salgia, R., Owonikoko, T., Malik, S., Karachaliou, N., Gandara, D. R., Slotman, B. J., Blackhall, F., Goss, G., Thomas, R., Rudin, C. M. & Hirsch, F. R., Jan 1 2016, In : Journal of Thoracic Oncology. 11, 4, p. 453-474 22 p.

Research output: Contribution to journalReview article

76 Scopus citations
2014

G protein-coupled receptors and the regulation of autophagy

Wauson, E. M., Dbouk, H. A., Ghosh, A. B. & Cobb, M. H., May 2014, In : Trends in Endocrinology and Metabolism. 25, 5, p. 274-282 9 p.

Research output: Contribution to journalReview article

26 Scopus citations
2013

Chromatin-tethered MAPKs

Klein, A. M., Zaganjor, E. & Cobb, M. H., 2013, In : Current Opinion in Cell Biology. 25, 2, p. 272-277 6 p.

Research output: Contribution to journalReview article

23 Scopus citations

Minireview: Nutrient sensing by G protein-coupled receptors

Wauson, E. M., Lorente-Rodríguez, A. & Cobb, M. H., Aug 1 2013, In : Molecular Endocrinology. 27, 8, p. 1188-1197 10 p.

Research output: Contribution to journalReview article

46 Scopus citations

Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells

Kalwat, M. A. & Thurmond, D. C., Aug 16 2013, In : Experimental and Molecular Medicine. 45, 8, e37.

Research output: Contribution to journalReview article

Open Access
56 Scopus citations
2012

Signal control through Raf: In sickness and in health

Osborne, J. K., Zaganjor, E. & Cobb, M. H., Jan 1 2012, In : Cell Research. 22, 1, p. 14-22 9 p.

Research output: Contribution to journalReview article

35 Scopus citations
2009

WNK kinases and blood pressure control

Cobb, M. H., Deaton, S. L. & Sengupta, S., Dec 1 2009, In : Current hypertension reports. 11, 6, p. 421-426 6 p.

Research output: Contribution to journalReview article

11 Scopus citations
2008

The roles of MAPKs in disease

Lawrence, M. C., Jivan, A., Shao, C., Duan, L., Goad, D., Zaganjor, E., Osborne, J., McGlynn, K., Stippec, S., Earnest, S., Chen, W. & Cobb, M. H., Apr 1 2008, In : Cell Research. 18, 4, p. 436-442 7 p.

Research output: Contribution to journalReview article

136 Scopus citations
2007

Differential regulation and properties of MAPKs

Raman, M., Chen, W. & Cobb, M. H., May 14 2007, In : Oncogene. 26, 22, p. 3100-3112 13 p.

Research output: Contribution to journalReview article

948 Scopus citations

WNKs: Protein kinases with a unique kinase domain

Huang, C. L., Cha, S. K., Wang, H. R., Xie, J. & Cobb, M. H., Oct 31 2007, In : Experimental and Molecular Medicine. 39, 5, p. 565-573 9 p.

Research output: Contribution to journalReview article

Open Access
36 Scopus citations
2006

Activation of MEKK1 by Rho GTPases

Chen, Z. & Cobb, M. H., Jan 1 2006, In : Methods in Enzymology. 406, p. 468-478 11 p., 35.

Research output: Contribution to journalReview article

3 Scopus citations

Role of with-no-lysine [K] kinases in the pathogenesis of Gordon's syndrome

Xie, J., Craig, L., Cobb, M. H. & Huang, C. L., Sep 1 2006, In : Pediatric Nephrology. 21, 9, p. 1231-1236 6 p.

Research output: Contribution to journalReview article

40 Scopus citations
2005

Phosphoproteomics: New insights into cellular signaling

Mumby, M. & Brekken, D., Sep 23 2005, In : Genome biology. 6, 9, 230.

Research output: Contribution to journalReview article

34 Scopus citations
2004

MAP kinases and their roles in pancreatic beta-cells.

Khoo, S., Gibson, T. B., Arnette, D., Lawrence, M., January, B., McGlynn, K., Vanderbilt, C. A., Griffen, S. C., German, M. S. & Cobb, M. H., 2004, In : Cell biochemistry and biophysics. 40, 3 Suppl, p. 191-200 10 p.

Research output: Contribution to journalReview article

20 Scopus citations
2003

MAP Kinase Modules: Many Roads Home

Raman, M. & Cobb, M. H., Nov 11 2003, In : Current Biology. 13, 22, p. R886-R888

Research output: Contribution to journalReview article

90 Scopus citations
2002

Overview of the alliance for cellular signaling

Gilman, A. G., Dec 12 2002, In : Nature. 420, 6916, p. 703-706 4 p.

Research output: Contribution to journalReview article

109 Scopus citations

Pharmacological inhibitors of MAPK pathways

English, J. M. & Cobb, M. H., Jan 1 2002, In : Trends in Pharmacological Sciences. 23, 1, p. 40-45 6 p.

Research output: Contribution to journalReview article

373 Scopus citations
2001

ERKs weigh in on ribosome mass

Gallagher, E. D. & Cobb, M. H., Nov 21 2001, In : Molecular cell. 8, 5, p. 932-933 2 p.

Research output: Contribution to journalReview article

2 Scopus citations

Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions

Pearson, G., Robinson, F., Gibson, T. B., Xu, B. E., Karandikar, M., Berman, K. & Cobb, M. H., May 31 2001, In : Endocrine reviews. 22, 2, p. 153-183 31 p.

Research output: Contribution to journalReview article

3137 Scopus citations
1999

Scaffolding and protein interactions in MAP kinase modules

Karandikar, M. & Cobb, M. H., Nov 1999, In : Cell Calcium. 26, 5, p. 219-226 8 p.

Research output: Contribution to journalReview article

25 Scopus citations
1991

Extracellular signal-regulated kinases: ERKs in progress

Cobb, M. H., Boulton, T. G. & Robbins, D. J., Dec 1991, In : Molecular biology of the cell. 2, 12, p. 965-978 14 p.

Research output: Contribution to journalReview article

415 Scopus citations
1984

The insulin receptor and tyrosine protein kinase activity

Cobb, M. H. & Rosen, O. M., 1984, In : BBA - Reviews on Cancer. 738, 1-2, p. 1-8 8 p.

Research output: Contribution to journalReview article

24 Scopus citations