Pharmacology - Collins Lab

Research Output 2006 2019

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2019

A rotifer-derived paralytic compound prevents transmission of schistosomiasis to a mammalian host

Gao, J., Yang, N., Lewis, F. A., Yau, P., Collins, J. J., Sweedler, J. V. & Newmark, P. A., Oct 1 2019, In : PLoS biology. 17, 10, p. e3000485

Research output: Contribution to journalArticle

Open Access
schistosomiasis
Schistosoma
Schistosomiasis
Rotifera
Cercaria
2 Citations (Scopus)
Open Access
Schistosoma
Schistosoma mansoni
in vitro culture
Ovum
Parasites
2018
5 Citations (Scopus)

Flatworm-specific transcriptional regulators promote the specification of tegumental progenitors in Schistosoma mansoni

Wendt, G. R., Collins, J. N., Pei, J., Pearson, M. S., Bennett, H. M., Loukas, A., Berriman, M., Grishin, N. V. & Collins, J. J., Mar 20 2018, In : eLife. 7

Research output: Contribution to journalArticle

Platyhelminths
Schistosoma mansoni
Maintenance
Specifications
Parasites
2017
4 Citations (Scopus)

MiR-277/4989 regulate transcriptional landscape during juvenile to adult transition in the parasitic helminth Schistosoma mansoni

Protasio, A. V., van Dongen, S., Collins, J., Quintais, L., Ribeiro, D. M., Sessler, F., Hunt, M., Rinaldi, G., Collins, J. J., Enright, A. J. & Berriman, M., May 23 2017, In : PLoS Neglected Tropical Diseases. 11, 5, e0005559.

Research output: Contribution to journalArticle

Schistosoma mansoni
Helminths
MicroRNAs
Sexual Development
Schistosomiasis
2016
17 Citations (Scopus)

Identification of new markers for the Schistosoma mansoni vitelline lineage

Wang, J. & Collins, J. J., Mar 3 2016, (Accepted/In press) In : International Journal for Parasitology.

Research output: Contribution to journalArticle

Schistosoma mansoni
Ovum
Parasites
In Situ Hybridization
Testis
9 Citations (Scopus)

Mass spectrometry imaging and identification of peptides associated with cephalic ganglia regeneration in Schmidtea mediterranea

Ong, T. H., Romanova, E. V., Roberts-Galbraith, R. H., Yang, N., Zimmerman, T. A., Collins, J. J., Lee, J. E., Kelleher, N. L., Newmark, P. A. & Sweedler, J. V., Apr 8 2016, In : Journal of Biological Chemistry. 291, 15, p. 8109-8120 12 p.

Research output: Contribution to journalArticle

Ganglia
Mass spectrometry
Regeneration
Mass Spectrometry
Head
5 Citations (Scopus)

NF-YB Regulates Spermatogonial Stem Cell Self-Renewal and Proliferation in the Planarian Schmidtea mediterranea

Iyer, H., Collins, J. J. & Newmark, P. A., Jun 1 2016, In : PLoS Genetics. 12, 6, e1006109.

Research output: Contribution to journalArticle

Planarians
stem cells
Stem Cells
stem
Germ Cells
16 Citations (Scopus)

Stem cell progeny contribute to the schistosome host-parasite interface

Collins, J. J., Wendt, G. R., Iyer, H. & Newmark, P. A., Mar 22 2016, In : eLife. 5, MARCH2016, e12473.

Research output: Contribution to journalArticle

Stem cells
Parasites
Stem Cells
Cells
Adult Stem Cells
5 Citations (Scopus)
Schistosoma mansoni
Parasites
Stem Cells
Cell Proliferation
RNA Interference
2015
1 Citation (Scopus)

Correction to: Genome-Wide Analyses Reveal a Role for Peptide Hormones in Planarian Germline Development(PLoS Biol, (2015), 13,8)

Collins, J. J., Hou, X., Romanova, E. V., Lambrus, B. G., Miller, C. M., Saberi, A., Sweedler, J. V. & Newmark, P. A., Aug 14 2015, In : PLoS Biology. 13, 8, e1002234.

Research output: Contribution to journalArticle

Planarians
peptide hormones
Peptide Hormones
germ cells
Genome
5 Citations (Scopus)

Tryptophan hydroxylase is required for eye melanogenesis in the planarian schmidtea mediterranea

Lambrus, B. G., Cochet-Escartin, O., Gao, J., Newmark, P. A., Collins, E. M. S. & Collins, J. J., May 1 2015, In : PLoS One. 10, 5, e0127074.

Research output: Contribution to journalArticle

Planarians
Tryptophan Hydroxylase
melanogenesis
Pigments
tryptophan
2014
5 Citations (Scopus)

A lophotrochozoan-specific nuclear hormone receptor is required for reproductive system development in the planarian

Tharp, M. E., Collins, J. J. & Newmark, P. A., Dec 1 2014, In : Developmental Biology. 396, 1, p. 150-157 8 p.

Research output: Contribution to journalArticle

Planarians
Cytoplasmic and Nuclear Receptors
Germ Cells
Carisoprodol
Hormones
2013
105 Citations (Scopus)

Adult somatic stem cells in the human parasite Schistosoma mansoni

Collins, J. J., Wang, B., Lambrus, B. G., Tharp, M. E., Iyer, H. & Newmark, P. A., Feb 28 2013, In : Nature. 494, 7438, p. 476-479 4 p.

Research output: Contribution to journalArticle

Adult Stem Cells
Schistosoma mansoni
Parasites
Platyhelminths
Planarians
24 Citations (Scopus)

A sex-specific transcription factor controls male identity in a simultaneous hermaphrodite

Chong, T., Collins, J. J., Brubacher, J. L., Zarkower, D. & Newmark, P. A., 2013, In : Nature Communications. 4, 1814.

Research output: Contribution to journalArticle

Transcription Factors
Genes
Accessories
Conservation
Animals
56 Citations (Scopus)

Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni

Wang, B., Collins, J. J. & Newmark, P. A., Jul 30 2013, In : eLife. 2013, 2, e00768.

Research output: Contribution to journalArticle

Schistosoma mansoni
Stem cells
Stem Cells
Maintenance
Platyhelminths
22 Citations (Scopus)

It's No Fluke: The Planarian as a Model for Understanding Schistosomes

Collins, J. J. & Newmark, P. A., Jul 2013, In : PLoS Pathogens. 9, 7, e1003396.

Research output: Contribution to journalArticle

Planarians
Trematoda
2011
30 Citations (Scopus)

Whole mount in situ hybridization methodology for Schistosoma mansoni

Cogswell, A. A., Collins, J. J., Newmark, P. A. & Williams, D. L., Jul 2011, In : Molecular and Biochemical Parasitology. 178, 1-2, p. 46-50 5 p.

Research output: Contribution to journalArticle

Schistosoma mansoni
In Situ Hybridization
Monophenol Monooxygenase
Genomics
Complement System Proteins
2010
140 Citations (Scopus)

Genome-wide analyses reveal a role for peptide hormones in planarian germline development

Collins, J. J., Hou, X., Romanova, E. V., Lambrus, B. G., Miller, C. M., Saberi, A., Sweedler, J. V. & Newmark, P. A., Oct 2010, In : PLoS Biology. 8, 10, e1000509.

Research output: Contribution to journalArticle

Platyhelminths
Planarians
peptide hormones
Peptide Hormones
Platyhelminthes
2008
26 Citations (Scopus)

The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan

Collins, J. J., Evason, K., Pickett, C. L., Schneider, D. L. & Kornfeld, K., Oct 2008, In : PLoS Genetics. 4, 10, e1000230.

Research output: Contribution to journalArticle

Ethosuximide
anticonvulsants
Anticonvulsants
defect
mutation
53 Citations (Scopus)

Valproic acid extends Caenorhabditis elegans lifespan

Evason, K., Collins, J. J., Huang, C., Hughes, S. & Kornfeld, K., Jun 2008, In : Aging Cell. 7, 3, p. 305-317 13 p.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Valproic Acid
Trimethadione
Anticonvulsants
Pharmaceutical Preparations
2006
83 Citations (Scopus)

Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans

Collins, J. J., Evason, K. & Kornfeld, K., Oct 2006, In : Experimental Gerontology. 41, 10, p. 1032-1039 8 p.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Aging of materials
Pharmacology
Trimethadione
Ethosuximide