Research output per year
Research output per year
- 1 - 50 out of 215 results
Search results
-
2024
Editorial: Nucleic Acids Research virtual issue dedicated to nucleic acid therapeutics, 2018–2023
Belgrad, J., Fakih, H. H., Johnson, K. C. & Corey, D. R., Jan 25 2024, In: Nucleic acids research. 52, 2, p. 511-512 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access1 Scopus citations -
Nuclear localization of Argonaute 2 is affected by cell density and may relieve repression by microRNAs
Johnson, K. C., Kilikevicius, A., Hofman, C., Hu, J., Liu, Y., Aguilar, S., Graswich, J., Han, Y., Wang, T., Westcott, J. M., Brekken, R. A., Peng, L., Karagkounis, G. & Corey, D. R., Feb 28 2024, In: Nucleic acids research. 52, 4, p. 1930-1952 23 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting RNA with synthetic oligonucleotides: Clinical success invites new challenges
Hofman, C. R. & Corey, D. R., Jan 18 2024, In: Cell Chemical Biology. 31, 1, p. 125-138 14 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
2023
RNAi in cell nuclei: potential for a new layer of biological regulation and a new strategy for therapeutic discovery
Johnson, K. C. & Corey, D. R., Apr 2023, In: RNA. 29, 4, p. 415-422 8 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2022
Challenges and Opportunities for Nucleic Acid Therapeutics
Corey, D. R., Damha, M. J. & Manoharan, M., Feb 2022, In: Nucleic Acid Therapeutics. 32, 1, p. 8-13 6 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
Difficulties translating antisense-mediated activation of Frataxin expression from cell culture to mice
Kilikevicius, A., Wang, J., Shen, X., Rigo, F., Prakash, T. P., Napierala, M. & Corey, D. R., 2022, In: RNA Biology. 19, 1, p. 364-372 9 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Editorial: Critical reviews and perspectives in Nucleic Acids Research
Corey, D. R. & Ulrich, H. D., Jul 22 2022, In: Nucleic acids research. 50, 13, p. 7201 1 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Reexamining assumptions about miRNA-guided gene silencing
Kilikevicius, A., Meister, G. & Corey, D. R., Jan 25 2022, In: Nucleic acids research. 50, 2, p. 617-634 18 p.Research output: Contribution to journal › Review article › peer-review
Open Access55 Scopus citations -
2021
Argonaute binding within human nuclear RNA and its impact on alternative splicing
CHU, YONGJUN., YOKOTA, SHINNICHI., LIU, JING., KILIKEVICIUS, AUDRIUS., JOHNSON, KRYSTAL. C. & COREY, DAVID. R., Sep 2021, In: RNA. 27, 9, p. 991-1003 13 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing
JOHNSON, SAMANTHA. T., CHU, YONGJUN., LIU, JING. & COREY, DAVID. R., Sep 2021, In: RNA. 27, 9, p. 1004-1016 13 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2020
Analyzing pre-symptomatic tissue to gain insights into the molecular and mechanistic origins of late-onset degenerative trinucleotide repeat disease
Chu, Y., Hu, J., Liang, H., Kanchwala, M., Xing, C., Beebe, W., Bowman, C. B., Gong, X., Corey, D. R. & Vinod Mootha, V., Jul 9 2020, In: Nucleic acids research. 48, 12, p. 6740-6758 19 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Argonaute binding within 3′-untranslated regions poorly predicts gene repression
Chu, Y., Kilikevicius, A., Liu, J., Johnson, K. C., Yokota, S. & Corey, D. R., Jul 27 2020, In: Nucleic acids research. 48, 13, p. 7439-7453 15 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Delivery of Antisense Oligonucleotides to the Cornea
Chau, V. Q., Hu, J., Gong, X., Hulleman, J. D., Ufret-Vincenty, R. L., Rigo, F., Prakash, T. P., Corey, D. R. & Vinod Mootha, V., Aug 2020, In: Nucleic Acid Therapeutics. 30, 4, p. 207-214 8 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Limits of using oligonucleotides for allele-selective inhibition at trinucleotide repeat sequences–targeting the CAG repeat within ataxin-1
Hu, J. & Corey, D. R., Feb 20 2020, In: Nucleosides, Nucleotides and Nucleic Acids. 39, 1-3, p. 185-194 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Progress towards drug discovery for Friedreich's Ataxia: Identifying synthetic oligonucleotides that more potently activate expression of human frataxin protein
Shen, X., Wong, J., Prakash, T. P., Rigo, F., Li, Y., Napierala, M. & Corey, D. R., Jun 1 2020, In: Bioorganic and Medicinal Chemistry. 28, 11, 115472.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
The 10th Oligonucleotide Therapy Approved: Golodirsen for Duchenne Muscular Dystrophy
Aartsma-Rus, A. & Corey, D. R., Apr 2020, In: Nucleic Acid Therapeutics. 30, 2, p. 67-70 4 p.Research output: Contribution to journal › Review article › peer-review
82 Scopus citations -
Trinucleotide repeat-targeting dCas9 as a therapeutic strategy for fuchs’ endothelial corneal dystrophy
Rong, Z., Gong, X., Hulleman, J. D., Corey, D. R. & Mootha, V. V., 2020, In: Translational Vision Science and Technology. 9, 9, p. 1-10 10 p., 47.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2019
CHAPTER 2: Mechanisms of Antisense Oligonucleotides
Liu, Z. & Corey, D. R., 2019, Therapies for Retinal Degeneration: Targeting Common Processes. Gait, M. J. & Agrawal, S. (eds.). 68 ed. Royal Society of Chemistry, p. 22-31 10 p. (RSC Drug Discovery Series; vol. 2019-January, no. 68).Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Duplex RNAs and ss-siRNAs Block RNA Foci Associated with Fuchs' Endothelial Corneal Dystrophy
Hu, J., Shen, X., Rigo, F., Prakash, T. P., Mootha, V. V. & Corey, D. R., Apr 2019, In: Nucleic Acid Therapeutics. 29, 2, p. 73-81 9 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Efficient electroporation of neuronal cells using synthetic oligonucleotides: Identifying duplex RNA and antisense oligonucleotide activators of human frataxin expression
Shen, X., Beasley, S., Putman, J. N., Li, Y., Prakash, T. P., Rigo, F., Napierala, M. & Corey, D. R., 2019, In: RNA. 25, 9, p. 1118-1129 12 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes
Liu, Z., Johnson, S. T., Zhang, Z. & Corey, D. R., Dec 2019, In: Nucleic Acid Therapeutics. 29, 6, p. 323-334 12 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Guidelines for Experiments Using Antisense Oligonucleotides and Double-Stranded RNAs
Gagnon, K. T. & Corey, D. R., Jun 2019, In: Nucleic Acid Therapeutics. 29, 3, p. 116-122 7 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Quantitative studies of muscleblind proteins and their interaction with tcf4 RNA foci support involvement in the mechanism of fuchs' dystrophy
Rong, Z., Hu, J., Corey, D. R. & Mootha, V. V., Sep 1 2019, In: Investigative Ophthalmology and Visual Science. 60, 12, p. 3980-3991 12 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2018
Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion
Shen, X., Kilikevicius, A., O'Reilly, D., Prakash, T. P., Damha, M. J., Rigo, F. & Corey, D. R., Sep 15 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 17, p. 2850-2855 6 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Activation of frataxin protein expression by antisense oligonucleotides targeting the mutant expanded repeat
Li, L., Shen, X., Liu, Z., Norrbom, M., Prakash, T. P., O'Reilly, D., Sharma, V. K., Damha, M. J., Watts, J. K., Rigo, F. & Corey, D. R., Feb 2018, In: Nucleic Acid Therapeutics. 28, 1, p. 23-33 11 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs
Shen, X. & Corey, D. R., Feb 28 2018, In: Nucleic acids research. 46, 4, p. 1584-1600 17 p.Research output: Contribution to journal › Article › peer-review
Open Access456 Scopus citations -
Editorial: Nucleic Acids Research and Nucleic Acid Therapeutics
Stoddard, B. L., Khvorova, A., Corey, D. R., Dynan, W. S. & Fox, K. R., Feb 28 2018, In: Nucleic acids research. 46, 4, p. 1563-1564 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access7 Scopus citations -
Oligonucleotides targeting TCF4 triplet repeat expansion inhibit RNA foci and mis-splicing in Fuchs' dystrophy
Hu, J., Rong, Z., Gong, X., Zhou, Z., Sharma, V. K., Xing, C., Watts, J. K., Corey, D. R. & Mootha, V., Mar 15 2018, In: Human molecular genetics. 27, 6, p. 1015-1026 12 p.Research output: Contribution to journal › Article › peer-review
Open Access47 Scopus citations -
The Requirement for GW182 Scaffolding Protein Depends on Whether Argonaute Is Mediating Translation, Transcription, or Splicing
Liu, J., Liu, Z. & Corey, D. R., Sep 4 2018, In: Biochemistry. 57, 35, p. 5247-5256 10 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2017
c9orf72 Disease-Related Foci Are Each Composed of One Mutant Expanded Repeat RNA
Liu, J., Hu, J., Ludlow, A. T., Pham, J. T., Shay, J. W., Rothstein, J. D. & Corey, D. R., Feb 16 2017, In: Cell Chemical Biology. 24, 2, p. 141-148 8 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription
Hicks, J. A., Li, L., Matsui, M., Chu, Y., Volkov, O., Johnson, K. C. & Corey, D. R., Aug 15 2017, In: Cell Reports. 20, 7, p. 1543-1552 10 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Non-coding RNAs as drug targets
Matsui, M. & Corey, D. R., Mar 1 2017, In: Nature Reviews Drug Discovery. 16, 3, p. 167-179 13 p.Research output: Contribution to journal › Review article › peer-review
Open Access739 Scopus citations -
Nusinersen, an antisense oligonucleotide drug for spinal muscular atrophy
Corey, D. R., Mar 29 2017, In: Nature neuroscience. 20, 4, p. 497-499 3 p.Research output: Contribution to journal › Article › peer-review
187 Scopus citations -
Recognition of c9orf72 Mutant RNA by Single-Stranded Silencing RNAs
Hu, J., Rigo, F., Prakash, T. P. & Corey, D. R., Apr 2017, In: Nucleic Acid Therapeutics. 27, 2, p. 87-94 8 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
RNA-mediated gene activation: Identifying a candidate RNA for preclinical development
Corey, D. R., 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 161-171 11 p. (Advances in Experimental Medicine and Biology; vol. 983).Research output: Chapter in Book/Report/Conference proceeding › Chapter
3 Scopus citations -
2016
Activating frataxin expression by repeat-targeted nucleic acids
Li, L., Matsui, M. & Corey, D. R., Feb 4 2016, In: Nature communications. 7, 10606.Research output: Contribution to journal › Article › peer-review
Open Access74 Scopus citations -
Argonaute 2-dependent regulation of gene expression by single-stranded miRNA mimics
Matsui, M., Prakash, T. P. & Corey, D. R., May 1 2016, In: Molecular Therapy. 24, 5, p. 946-955 10 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Doubts about therapy for neurological diseases with antisense oligonucleotides-reply
Corey, D. R., Dec 1 2016, In: JAMA neurology. 73, 12, p. 1502-1503 2 p.Research output: Contribution to journal › Letter › peer-review
-
HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing
Liu, H., Liang, C., Kollipara, R. K., Matsui, M., Ke, X., Jeong, B. C., Wang, Z., Yoo, K. S., Yadav, G. P., Kinch, L. N., Grishin, N. V., Nam, Y., Corey, D. R., Kittler, R. & Liu, Q., Aug 4 2016, In: Molecular cell. 63, 3, p. 420-432 13 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Pathogenic C9ORF72 Antisense Repeat RNA Forms a Double Helix with Tandem C:C Mismatches
Dodd, D. W., Tomchick, D. R., Corey, D. R. & Gagnon, K. T., Mar 8 2016, In: Biochemistry. 55, 9, p. 1283-1286 4 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Regulation of mammalian transcription and splicing by Nuclear RNAi
Kalantari, R., Chiang, C. M. & Corey, D. R., Jan 29 2016, In: Nucleic acids research. 44, 2, p. 524-537 14 p.Research output: Contribution to journal › Article › peer-review
Open Access77 Scopus citations -
Synthetic nucleic acids and treatment of neurological diseases
Corey, D. R., Oct 1 2016, In: JAMA neurology. 73, 10, p. 1238-1242 5 p.Research output: Contribution to journal › Review article › peer-review
Open Access8 Scopus citations -
2015
Design and bioinformatics analysis of genome-wide CLIP experiments
Wang, T., Xiao, G., Chu, Y., Zhang, M. Q., Corey, D. R. & Xie, Y., Apr 23 2015, In: Nucleic acids research. 43, 11, p. 5263-5274 12 p.Research output: Contribution to journal › Review article › peer-review
54 Scopus citations -
Engineering Duplex RNAs for Challenging Targets: Recognition of GGGGCC/CCCCGG Repeats at the ALS/FTD C9orf72 Locus
Hu, J., Liu, J., Li, L., Gagnon, K. T. & Corey, D. R., Nov 19 2015, In: Chemistry and Biology. 22, 11, p. 1505-1511 7 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Identification and validation of miRNA target sites within nontraditional miRNA targets
Younger, S. T. & Corey, D. R., 2015, In: Methods in Molecular Biology. 1206, p. 53-67 15 p.Research output: Contribution to journal › Article › peer-review
-
Intramolecular circularization increases efficiency of RNA sequencing and enables CLIP-Seq of nuclear RNA from human cells
Chu, Y., Wang, T., Dodd, D., Xie, Y., Janowski, B. A. & Corey, D. R., Mar 3 2015, In: Nucleic acids research. 43, 11, e75.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Modulation of Splicing by Single-Stranded Silencing RNAs
Liu, J., Hu, J., Hicks, J. A., Prakash, T. P. & Corey, D. R., Jun 1 2015, In: Nucleic Acid Therapeutics. 25, 3, p. 113-120 8 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Reduced Expression of Argonaute 1, Argonaute 2, and TRBP Changes Levels and Intracellular Distribution of RNAi Factors
Matsui, M., Li, L., Janowski, B. A. & Corey, D. R., Aug 5 2015, In: Scientific reports. 5, 12855.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Stepping toward therapeutic CRISPR
Gagnon, K. T. & Corey, D. R., Dec 22 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 51, p. 15536-15537 2 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access7 Scopus citations -
2014
Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAs
Hu, J., Liu, J., Narayanannair, K. J., Lackey, J. G., Kuchimanchi, S., Rajeev, K. G., Manoharan, M., Swayze, E. E., Lima, W. F., Prakash, T. P., Xiang, Q., Martinez, C. & Corey, D. R., Jul 22 2014, In: Biochemistry. 53, 28, p. 4510-4518 9 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations