Pharmacology - Ross Lab

Research output

Research output per year 1972 1977 1981 1982 1984 1985 1988 1990 1991 1995 1996 1997 1999 2001 2018

• 108 Article
• 10 Review article
• 3 Comment/debate
• 1 Chapter
• 1 More
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2018

  Suppression of RGSz1 function optimizes the actions of opioid analgesics by mechanisms that involve the Wnt/β-catenin pathway

  Gaspari, S., Purushothaman, I., Cogliani, V., Sakloth, F., Neve, R. L., Howland, D., Ring, R. H., Ross, E. M., Shen, L. & Zachariou, V., Feb 27 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 9, p. E2085-E2094

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • GTP-Binding Protein Regulators 100%
  • Catenins 84%
  • Wnt Signaling Pathway 75%
  • Opioid Analgesics 59%
  • Morphine 26%
  22 Scopus citations
• 2017

  The binding of activated G_q to phospholipase C- exhibits anomalous affinity

  Navaratnarajah, P., Gershenson, A. & Ross, E. M., Oct 6 2017, In: Journal of Biological Chemistry. 292, 40, p. 16787-16801 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phosphatidylinositol 100%
  • Type C Phospholipases 92%
  • Fluorescence Correlation Spectroscopy 51%
  • Inositol 49%
  • Hysteresis 40%
  6 Scopus citations
• 2016

  Amino acids regulate mTORC1 by an obligate two-step mechanism

  Dyachok, J., Earnest, S., Iturraran, E. N., Cobb, M. H. & Ross, E. M., Oct 21 2016, In: Journal of Biological Chemistry. 291, 43, p. 22414-22426 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mechanistic Target of Rapamycin Complex 1 100%
  • Amino Acids 55%
  • Acid 27%
  • Aminoacylation 12%
  • L-Asparagine 12%
  53 Scopus citations

• Intrinsic Pleckstrin Homology (PH) domain motion in phospholipase C-β exposes a Gβγ protein binding site

  Kadamur, G. & Ross, E. M., May 20 2016, In: Journal of Biological Chemistry. 291, 21, p. 11394-11406 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pleckstrin Homology Domains 100%
  • Type C Phospholipases 81%
  • GTP-Binding Proteins 72%
  • Protein Binding 72%
  • Binding Sites 55%
  15 Scopus citations
• 2015

  Differential regulation of ERK1/2 and mTORC1 through T1R1/T1R3 in MIN6 cells

  Wauson, E. M., Guerra, M. L., Dyachok, J., McGlynn, K., Giles, J., Ross, E. M. & Cobb, M. H., Jul 31 2015, In: Molecular Endocrinology. 29, 8, p. 1114-1122 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mechanistic Target of Rapamycin Complex 1 100%
  • Aminoacylation 43%
  • Amino Acids 41%
  • Nutrients 25%
  • FR900359 20%
  15 Scopus citations
• 2013

  Mammalian phospholipase C

  Kadamur, G. & Ross, E. M., Feb 10 2013, In: Annual review of physiology. 75, p. 127-154 28 p.

  Research output: Contribution to journal › Review article › peer-review

  • Type C Phospholipases 100%
  • Diglycerides 71%
  • Nexus 42%
  • Heterotrimeric GTP-Binding Proteins 39%
  • Inositol 1,4,5-Trisphosphate 37%
  351 Scopus citations
• 2012

  Activation Biosensor for G Protein-Coupled Receptors: A FRET-Based m1 Muscarinic Activation Sensor That Regulates G_q

  Chang, S. & Ross, E. M., Sep 20 2012, In: PloS one. 7, 9, e45651.

  Research output: Contribution to journal › Article › peer-review

  • Energy Transfer 100%
  • Resonance Energy 96%
  • Parasympathomimetic Agent 95%
  • G-protein coupled receptors 93%
  • Biosensing Techniques 92%
  12 Scopus citations
• 2011

  Gα_qand phospholipase C-β: Turn on, turn off, and do it fast

  Ross, E. M., Feb 8 2011, In: Science signaling. 4, 159, pe5.

  Research output: Contribution to journal › Review article › peer-review

  • Type C Phospholipases 100%
  • GTPase-Activating Proteins 91%
  • GTP-Binding Proteins 89%
  • Protein 37%
  • RGS Proteins 34%
  25 Scopus citations

• Synergistic Ca²⁺ responses by Gα_i- and Gα_q-coupled G-protein-coupled receptors require a single PLCβ isoform that is sensitive to both Gβγ and Gα_q

  Rebres, R. A., Roach, T. I. A., Fraser, I. D. C., Philip, F., Moon, C., Lin, K. M., Liu, J., Santat, L., Cheadle, L., Ross, E. M., Simon, M. I. & Seaman, W. E., Jan 14 2011, In: Journal of Biological Chemistry. 286, 2, p. 942-951 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Gq-G11 GTP-Binding Protein alpha Subunits 100%
  • Phospholipases 77%
  • G-Protein-Coupled Receptors 64%
  • Mutation 54%
  • Protein Isoforms 51%
  48 Scopus citations

• WNK1 promotes PIP₂ synthesis to coordinate growth factor and GPCR-G_q signaling

  An, S. W., Cha, S. K., Yoon, J., Chang, S., Ross, E. M. & Huang, C. L., Dec 6 2011, In: Current Biology. 21, 23, p. 1979-1987 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Growth Factor 100%
  • growth factors 80%
  • phosphotransferases (kinases) 72%
  • Intercellular Signaling Peptides and Proteins 69%
  • Phosphotransferases 65%
  27 Scopus citations
• 2010

  Synergistic activation of phospholipase C-β3 by Gα_q and Gβγ describes a simple two-state coincidence detector

  Philip, F., Kadamur, G., Silos, R. G., Woodson, J. & Ross, E. M., Aug 10 2010, In: Current Biology. 20, 15, p. 1327-1335 9 p.

  Research output: Contribution to journal › Article › peer-review

  • phospholipase C 100%
  • Type C Phospholipases 96%
  • synergism 95%
  • detectors 89%
  • Ligands 61%
  63 Scopus citations
• 2008

  Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAP

  Turcotte, M., Tang, W. & Ross, E. M., Aug 2008, In: PLoS Computational Biology. 4, 8, e1000148.

  Research output: Contribution to journal › Article › peer-review

  • G Protein 100%
  • GTPase-activating proteins 86%
  • GTPase-Activating Proteins 81%
  • Receptor 77%
  • G-proteins 64%
  38 Scopus citations

• Coordinating Speed and Amplitude in G-Protein Signaling

  Ross, E. M., Sep 9 2008, In: Current Biology. 18, 17, p. R777-R783

  Research output: Contribution to journal › Review article › peer-review

  • GTPase-activating proteins 100%
  • GTPase-Activating Proteins 94%
  • G-proteins 73%
  • Guanosine Triphosphate 73%
  • GTP-Binding Proteins 69%
  75 Scopus citations

• Coordinating Speed and Amplitude in G-Protein Signaling (DOI:10.1016/j.cub.2008.07.035)

  Ross, E. M., Dec 9 2008, In: Current Biology. 18, 23, p. 1896 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review
• 2007

  Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway

  Jiang, L. I., Collins, J., Davis, R., Lin, K. M., DeCamp, D., Roach, T., Hsueh, R., Rebres, R. A., Ross, E. M., Taussig, R., Fraser, I. & Sternweis, P. C., Apr 6 2007, In: Journal of Biological Chemistry. 282, 14, p. 10576-10584 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Sphingosine 1-Phosphate 100%
  • Energy Transfer 83%
  • sphingosine 1-phosphate 82%
  • Bioluminescence 75%
  • Fluorescence Resonance Energy Transfer 62%
  260 Scopus citations
• 2006

  Gβγinhibits Gα GTPase-activating proteins by inhibition of Gα-GTP binding during stimulation by receptor

  Tang, W., Tu, Y., Nayak, S. K., Woodson, J., Jehl, M. & Ross, E. M., Feb 24 2006, In: Journal of Biological Chemistry. 281, 8, p. 4746-4753 8 p.

  Research output: Contribution to journal › Article › peer-review

  • GTPase-Activating Proteins 100%
  • Guanosine Triphosphate 78%
  • Protein 30%
  • Protein Subunits 23%
  • Type C Phospholipases 22%
  30 Scopus citations

• Structural determinants for phosphatidic acid regulation of phospholipase C-β₁

  Ross, E. M., Mateu, D., Gomes, A. V., Arana, C., Tran, T. & Litosch, I., Nov 3 2006, In: Journal of Biological Chemistry. 281, 44, p. 33087-33094 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Phosphatidic Acids 100%
  • Phosphatidic Acid 96%
  • Type C Phospholipases 84%
  • Signalling Molecule 7%
  • GTPase-Activating Proteins 7%
  31 Scopus citations
• 2005

  Q & A. Elliott Ross.

  Ross, E., Dec 6 2005, In: Current biology : CB. 15, 23, p. R942-943

  Research output: Contribution to journal › Article › peer-review

• Spinophilin regulates Ca²⁺ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors

  Wang, X., Zeng, W., Syombo, A. A., Tang, W., Ross, E. M., Barnes, A. P., Milgram, S. L., Penninger, J. M., Allen, P. B., Greengard, P. & Muallem, S., Apr 2005, In: Nature cell biology. 7, 4, p. 405-411 7 p.

  Research output: Contribution to journal › Article › peer-review

  • neurabin 100%
  • G-Protein-Coupled Receptors 57%
  • Adrenergic Receptors 36%
  • RGS Proteins 29%
  • GTP Phosphohydrolases 21%
  129 Scopus citations
• 2004

  Uncoupling conformational change from GTP hydrolysis in a heterotrimetric G protein α-subunit

  Thomas, C. J., Du, X., Li, P., Wang, Y., Ross, E. M. & Sprang, S. R., May 18 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 20, p. 7560-7565 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Protein Subunits 100%
  • Guanosine Triphosphate 92%
  • GTP-Binding Proteins 87%
  • Hydrolysis 80%
  • fluoroaluminum 65%
  26 Scopus citations
• 2003

  Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCβ GAP activities

  Shin, D. M., Dehoff, M., Luo, X., Kang, S. H., Tu, J., Nayak, S. K., Ross, E. M., Worley, P. E. & Muallem, S., Jul 21 2003, In: Journal of Cell Biology. 162, 2, p. 293-303 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Homer Scaffolding Proteins 100%
  • RGS Proteins 89%
  • G-Protein-Coupled Receptors 58%
  • Inositol 1,4,5-Trisphosphate Receptors 33%
  • Phosphoinositide Phospholipase C 11%
  79 Scopus citations

• Phosphorylation-regulated Inhibition of the G_z GTPase-activating Protein Activity of RGS Proteins by Synapsin I

  Tu, Y., Nayak, S. K., Woodson, J. & Ross, E. M., Dec 26 2003, In: Journal of Biological Chemistry. 278, 52, p. 52273-52281 9 p.

  Research output: Contribution to journal › Article › peer-review

  • RGS Proteins 100%
  • Synapsins 92%
  • GTPase-Activating Proteins 87%
  • Psychological Inhibition 52%
  • Phosphorylation 44%
  16 Scopus citations
• 2002

  Mutations in the carboxyl-terminal domain of phospholipase C-β1 delineate the dimer interface and a potential Gα_q interaction site

  Ilkaeva, O., Kinch, L. N., Paulssen, R. H. & Ross, E. M., Feb 8 2002, In: Journal of Biological Chemistry. 277, 6, p. 4294-4300 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Interface Potential 100%
  • GTPase-Activating Proteins 79%
  • Type C Phospholipases 65%
  • Mutation 49%
  • Protein 24%
  54 Scopus citations

• Overview of the alliance for cellular signaling

  Gilman, A. G., Dec 12 2002, In: Nature. 420, 6916, p. 703-706 4 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Cardiac Myocytes 100%
  • Immune System 85%
  • B-Lymphocytes 82%
  118 Scopus citations
• 2001

  Binding of regulator of G protein signaling (RGS) proteins to phospholipid bilayers. Contribution of location and/or orientation to GTPase-activating protein activity

  Tu, Y., Woodson, J. & Ross, E. M., Jun 8 2001, In: Journal of Biological Chemistry. 276, 23, p. 20160-20166 7 p.

  Research output: Contribution to journal › Article › peer-review

  • RGS Proteins 100%
  • GTPase-Activating Proteins 87%
  • Phospholipids 58%
  • Phospholipid 54%
  • GTP-Binding Proteins 32%
  53 Scopus citations

• Quantitative assays for GTPase-activating proteins

  Ross, E. M., 2001, In: Methods in Enzymology. 344, p. 601-617 17 p.

  Research output: Contribution to journal › Article › peer-review
  28 Scopus citations

• Quench-flow kinetic measurement of individual reactions of G-protein-catalyzed GTPase cycle

  Mukhopadhyay, S. & Ross, E. M., 2001, In: Methods in Enzymology. 344, p. 350-369 20 p.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• RGSZ1 and Ret RGS: Two of several splice variants from the gene RGS20

  Barker, S. A., Wang, J., Sierra, D. A. & Ross, E. M., Dec 2001, In: Genomics. 78, 3, p. 223-229 7 p.

  Research output: Contribution to journal › Article › peer-review

  • GTP-Binding Protein Regulators 100%
  • Exons 55%
  • Genes 26%
  • GTPase-Activating Proteins 25%
  • Open Reading Frames 18%
  30 Scopus citations
• 2000

  GTPase-activating proteins for heterotrimeric G proteins: Regulators of G Protein Signaling (RGS) and RGS-like proteins

  Ross, E. M. & Wilkie, T. M., 2000, In: Annual review of biochemistry. 69, p. 795-827 33 p.

  Research output: Contribution to journal › Review article › peer-review

  • RGS Proteins 100%
  • GTP-Binding Protein Regulators 96%
  • GTPase-Activating Proteins 87%
  • Heterotrimeric GTP-Binding Proteins 86%
  • GTP-Binding Proteins 43%
  957 Scopus citations
• 1999

  Kinetic control of guanine nucleotide binding to soluble Gα(q)

  Markin, V. S. & Ross, E. M., Jul 1 1999, In: Biochemical Pharmacology. 58, 1, p. 39-48 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Guanine Nucleotides 100%
  • GTP-Binding Proteins 80%
  • Guanine 78%
  • Nucleotide 66%
  • GDP 61%
  43 Scopus citations

• Modulation of the affinity and selectivity of RGS protein interaction with Gα subunits by a conserved asparagine/serine residue

  Posner, B. A., Mukhopadhyay, S., Tesmer, J. J., Gilman, A. G. & Ross, E. M., Jun 15 1999, In: Biochemistry. 38, 24, p. 7773-7779 7 p.

  Research output: Contribution to journal › Article › peer-review

  • RGS Proteins 100%
  • Serine Residue 82%
  • Asparagine 80%
  • Serine 62%
  • Guanosine Triphosphate 45%
  69 Scopus citations

• Palmitoylation of a conserved cysteine in the regulator of G protein signaling (RGS) domain modulates the GTPase-activating activity of RGS4 and RGS10

  Tu, Y., Popov, S., Slaughter, C. & Ross, E. M., Dec 31 1999, In: Journal of Biological Chemistry. 274, 53, p. 38260-38267 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Palmitoylation 100%
  • Lipoylation 87%
  • GTPase-Activating Proteins 71%
  • GTP Phosphohydrolases 70%
  • Protein Domains 62%
  89 Scopus citations

• Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins

  Mukhopadhyay, S. & Ross, E. M., Aug 17 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 17, p. 9539-9544 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • GTPase-Activating Proteins 100%
  • Guanosine Triphosphate 78%
  • Hydrolysis 68%
  • GTP Phosphohydrolases 21%
  • Type C Phospholipases 20%
  156 Scopus citations

• Reciprocal signaling between heterotrimeric G proteins and the p21- stimulated protein kinase

  Wang, J., Frost, J. A., Cobb, M. H. & Ross, E. M., Oct 29 1999, In: Journal of Biological Chemistry. 274, 44, p. 31641-31647 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Heterotrimeric GTP-Binding Proteins 100%
  • Protein Kinases 69%
  • GTPase-Activating Proteins 67%
  • Protein Kinase C 58%
  • p21-Activated Kinases 53%
  55 Scopus citations
• 1998

  Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticity

  Ingi, T., Krumins, A. M., Chidiac, P., Brothers, G. M., Chung, S., Snow, B. E., Barnes, C. A., Lanahan, A. A., Siderovski, D. P., Ross, E. M., Gilman, A. G. & Worley, P. F., Sep 15 1998, In: Journal of Neuroscience. 18, 18, p. 7178-7188 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • GTP-Binding Protein Regulators 100%
  • GTP-Binding Proteins 66%
  • Neuronal Plasticity 63%
  • GTP Phosphohydrolases 38%
  • Messenger RNA 38%
  265 Scopus citations

• RGSZ1, a G(z)-selective rgs protein in brain: Structure, membrane association, regulation by Gα(z) phosphorylation, and relationship to a G(z) gtpase-activating protein subfamily

  Wang, J., Ducret, A., Tu, Y., Kozasa, T., Aebersold, R. & Ross, E. M., Oct 2 1998, In: Journal of Biological Chemistry. 273, 40, p. 26014-26025 12 p.

  Research output: Contribution to journal › Article › peer-review

  • RGS Proteins 100%
  • GTPase-Activating Proteins 87%
  • Phosphorylation 44%
  • Protein Kinase C 40%
  • Membranes 38%
  136 Scopus citations

• The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signaling

  Zeng, W., Xu, X., Popov, S., Mukhopadhyay, S., Chidiac, P., Swistok, J., Danho, W., Yagaloff, K. A., Fisher, S. L., Ross, E. M., Muallem, S. & Wilkie, T. M., Dec 25 1998, In: Journal of Biological Chemistry. 273, 52, p. 34687-34690 4 p.

  Research output: Contribution to journal › Article › peer-review

  • GTPase-Activating Proteins 100%
  • Guanosine Triphosphate 78%
  • GTP-Binding Proteins 73%
  • Hydrolysis 68%
  • RGS Proteins 57%
  220 Scopus citations
• 1997

  A G(s)-selective analog of the receptor-mimetic peptide mastoparan binds to G(s)α in a kinked helical conformation

  Sukumar, M., Ross, E. M. & Higashijima, T., Mar 25 1997, In: Biochemistry. 36, 12, p. 3632-3639 8 p.

  Research output: Contribution to journal › Article › peer-review

  • mastoparan 100%
  • Mastoparan 98%
  • Peptide Receptors 76%
  • mastoparan X 46%
  • GTP-Binding Proteins 40%
  34 Scopus citations

• A GTPase-activating protein for the G protein Gα(z). Identification, purification, and mechanism of action

  Wang, J., Tu, Y., Woodson, J., Song, X. & Ross, E. M., Feb 28 1997, In: Journal of Biological Chemistry. 272, 9, p. 5732-5740 9 p.

  Research output: Contribution to journal › Article › peer-review

  • GTPase-Activating Proteins 100%
  • GTP-Binding Proteins 73%
  • Purification 49%
  • Protein 30%
  • Guanosine Triphosphate 28%
  65 Scopus citations

• Colloquium on signaling and molecular structure in pharmacology (La Jolla, California, March 11-12, 1997)

  Taylor, P., Ross, E. M., Sternweis, P. C., Neubig, R. R. & McCammon, J. A., Jan 1 1997, In: Molecular Pharmacology. 52, 1, p. 1-5 5 p.

  Research output: Contribution to journal › Article › peer-review

• Expression of human muscarinic cholinergic receptors in tobacco

  Mu, J. H., Chua, N. H. & Ross, E. M., May 1997, In: Plant Molecular Biology. 34, 2, p. 357-362 6 p.

  Research output: Contribution to journal › Article › peer-review

  • cholinergic receptors 100%
  • muscarine receptors 98%
  • Bony Callus 95%
  • Cholinergic Receptors 84%
  • Muscarinic Receptors 83%
  9 Scopus citations

• Guanosine Triphosphatase-Activating Proteins for Heterotrimeric G-Proteins

  Ross, E. M., Wang, J., Tu, Y. & Biddlecome, G. H., 1997, In: Advances in Pharmacology. 42, C, p. 458-461 4 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Inhibition of brain G(z) GAP and other RGS proteins by palmitoylation of G protein α subunits

  Tu, Y., Wang, J. & Ross, E. M., Nov 7 1997, In: Science. 278, 5340, p. 1132-1135 4 p.

  Research output: Contribution to journal › Article › peer-review

  • RGS Proteins 100%
  • Lipoylation 92%
  • GTPase-Activating Proteins 87%
  • Protein Subunits 73%
  • GTP-Binding Proteins 64%
  130 Scopus citations

• PDZ domain proteins: Scaffolds for signaling complexes

  Ranganathan, R. & Ross, E. M., Dec 1 1997, In: Current Biology. 7, 12, p. R770-R773

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • PDZ Domains 100%
  • scaffolding proteins 97%
  • protein domains 78%
  • photoreceptors 74%
  • Drosophila 61%
  137 Scopus citations
• 1996

  Carboxyl-terminal fragments of phospholipase C-β1 with intrinsic G(q) GTPase-activating protein (GAP) activity

  Paulssen, R. H., Woodson, J., Liu, Z. & Ross, E. M., 1996, In: Journal of Biological Chemistry. 271, 43, p. 26622-26629 8 p.

  Research output: Contribution to journal › Article › peer-review

  • GTPase-Activating Proteins 100%
  • Type C Phospholipases 82%
  • Protein 30%
  • Phospholipases 19%
  • GTP Phosphohydrolases 18%
  58 Scopus citations

• Erratum: Regulation of phospholipase C-β1 by G(q) and m1 muscarinic cholinergic receptor. Steady-state balance of receptor-mediated activation and GTPase-activating protein-promoted deactivation (Journal of Biological Chemistry (1996) 271 (7999-8007))

  Biddlecome, G. H., Berstein, G. & Ross, E. M., 1996, In: Journal of Biological Chemistry. 271, 52, p. 33705 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Functional importance of the amino terminus of G_qα

  Hepler, J. R., Biddlecome, G. H., Kleuss, C., Camp, L. A., Hofmann, S. L., Ross, E. M. & Gilman, A. G., Jan 5 1996, In: Journal of Biological Chemistry. 271, 1, p. 496-504 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Palmitates 100%
  • Lipoylation 76%
  • Sf9 Cells 74%
  • Palmitoylation 70%
  • Type C Phospholipases 60%
  100 Scopus citations

• Purification and characterization of phospholipase C-β1 mutants expressed in E. coli

  Meij, J. T. A. & Ross, E. M., Aug 23 1996, In: Biochemical and Biophysical Research Communications. 225, 3, p. 705-711 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Type C Phospholipases 100%
  • Escherichia coli 63%
  • GTPase-Activating Proteins 60%
  • Purification 60%
  • Effector 48%
  5 Scopus citations

• Regulation of phospholipase C-β1 by G_q and m1 muscarinic cholinergic receptor: Steady-state balance of receptor-mediated activation and GTPase-activating protein-promoted deactivation

  Biddlecome, G. H., Berstein, G. & Ross, E. M., Apr 5 1996, In: Journal of Biological Chemistry. 271, 14, p. 7999-8007 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Carbachol 100%
  • GTPase-Activating Proteins 92%
  • Cholinergic 86%
  • Parasympathomimetic Agent 84%
  • Type C Phospholipases 75%
  213 Scopus citations
• 1995

  Carboxyl-terminal domains in the avian β₁-adrenergic receptor that regulate agonist-promoted endocytosis

  Parker, E. M., Swigart, P., Nunnally, M. H., Perkins, J. P. & Ross, E. M., Mar 24 1995, In: Journal of Biological Chemistry. 270, 12, p. 6482-6487 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Adrenergic Agonists 100%
  • Endocytosis 79%
  • Agonist 37%
  • Adrenergic Receptors 37%
  • Turkeys 32%
  31 Scopus citations