Pharmacology - Wan Lab

Research output

Research output per year 1997 2010 2012 2013 2014 2015 2016 2017 2019 2020

• 44 Article
• 9 Review article
• 3 Comment/debate
• 3 Short survey
• 2 More
  • 1 Chapter
  • 1 Letter

Research output per year

Research output per year

Search results

• 2020

  Differential regulation of breast cancer bone metastasis by PARP1 and PARP2

  Zuo, H., Yang, D., Yang, Q., Tang, H., Fu, Y. X. & Wan, Y., Dec 1 2020, In: Nature communications. 11, 1, 1578.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Olaparib 100%
  • olaparib 83%
  • metastasis 78%
  • Bone Neoplasms 66%
  • breast 57%
  23 Scopus citations

• Opposing Functions of BRD4 Isoforms in Breast Cancer

  Wu, S. Y., Lee, C. F., Lai, H. T., Yu, C. T., Lee, J. E., Zuo, H., Tsai, S. Y., Tsai, M. J., Ge, K., Wan, Y. & Chiang, C. M., Jun 18 2020, In: Molecular cell. 78, 6, p. 1114-1132.e10

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Protein Isoforms 100%
  • Breast Neoplasms 79%
  • Proteins 45%
  • Cystatins 18%
  • Cathepsins 16%
  80 Scopus citations

• Retraction Note: miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2 (Nature, (2014), 512, 7515, (431-435), 10.1038/nature13375)

  Krzeszinski, J. Y., Wei, W., Huynh, H. D., Jin, Z., Wang, X., Chang, T. C., Xie, X. J., He, L., Mangala, L. S., Lopez-Berestein, G., Sood, A. K., Mendell, J. T. & Wan, Y., Jun 4 2020, In: Nature. 582, 7810, p. 134 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Osteoporosis 100%
  • Osteogenesis 99%
  • Neoplasm Metastasis 69%
  • Bone and Bones 67%
  6 Scopus citations
• 2019

  Author Correction: miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2 (Nature, (2014), 512, 7515, (431-435), 10.1038/nature13375)

  Krzeszinski, J. Y., Wei, W., Huynh, H. D., Jin, Z., Wang, X., Chang, T. C., Xie, X-J., He, L., Mangala, L. S., Lopez-Berestein, G., Sood, A. K., Mendell, J. T. & Wan, Y., Jan 1 2019, In: Nature.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Osteoporosis 100%
  • Osteogenesis 99%
  • Neoplasm Metastasis 69%
  • Bone and Bones 67%
  1 Scopus citations

• Metabolic Reprogramming in Mitochondria of Myeloid Cells

  Zuo, H. & Wan, Y., Dec 18 2019, In: Cells. 9, 1

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Myeloid Cells 100%
  • Mitochondria 80%
  • Metabolic 79%
  • Antiinflammatory 56%
  • Oxidative Phosphorylation 44%
  19 Scopus citations

• Molecular determinants for the polarization of macrophage and osteoclast

  Yang, D. & Wan, Y., Sep 1 2019, In: Seminars in Immunopathology. 41, 5, p. 551-563 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Osteoclasts 100%
  • Peroxisome Proliferator-Activated Receptors 77%
  • Macrophages 67%
  • VLDL receptor 51%
  • Iron-Sulfur Proteins 51%
  56 Scopus citations

• NR Supplementation During Lactation: Benefiting Mother and Child

  Yang, D. & Wan, Y., Apr 2019, In: Trends in Endocrinology and Metabolism. 30, 4, p. 225-227 3 p.

  Research output: Contribution to journal › Short survey › peer-review

  Open Access

  • nicotinamide-beta-riboside 100%
  • Lactation 61%
  • NAD 58%
  • Mothers 36%
  • Postpartum Period 27%
  3 Scopus citations
• 2018

  Milk lipid regulation at the maternal-offspring interface

  Yang, D., Huynh, H. D. & Wan, Y., Sep 2018, In: Seminars in Cell and Developmental Biology. 81, p. 141-148 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Milk 100%
  • Lipids 69%
  • Mothers 68%
  • Essential Fatty Acids 28%
  • Genetically Modified Animals 26%
  11 Scopus citations

• mTORC1 impedes osteoclast differentiation via calcineurin and NFATc1

  Huynh, H. D. & Wan, Y., Dec 1 2018, In: Communications Biology. 1, 1, 29.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • osteoclasts 100%
  • Immunosuppressive Agent 95%
  • Mechanistic Target of Rapamycin Complex 1 90%
  • Dephosphorylation 90%
  • Calcineurin 89%
  49 Scopus citations
• 2017

  Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis

  Chen, P., Zuo, H., Xiong, H., Kolar, M. J., Chu, Q., Saghatelian, A., Siegwart, D. J. & Wan, Y., Jan 17 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 3, p. 580-585 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • G-Protein-Coupled Receptors 100%
  • Lactic Acid 88%
  • Macrophages 69%
  • Breast Neoplasms 63%
  • Neoplasm Metastasis 61%
  269 Scopus citations

• High-Contrast Fluorescence Detection of Metastatic Breast Cancer Including Bone and Liver Micrometastases via Size-Controlled pH-Activatable Water-Soluble Probes

  Xiong, H., Zuo, H., Yan, Y., Occhialini, G., Zhou, K., Wan, Y. & Siegwart, D. J., Aug 4 2017, In: Advanced Materials. 29, 29, 1700131.

  Research output: Contribution to journal › Article › peer-review

  • Liver 100%
  • Fluorescence 95%
  • Bone 80%
  • Water Soluble 64%
  • Polyethylene glycols 53%
  64 Scopus citations

• Improved resection and prolonged overall survival with PD-1-IRDye800CW fluorescence probe-guided surgery and PD-1 adjuvant immunotherapy in 4T1 mouse model

  Du, Y., Sun, T., Liang, X., Li, Y., Jin, Z., Xue, H., Wan, Y. & Tian, J., Nov 21 2017, In: International Journal of Nanomedicine. 12, p. 8337-8351 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adjuvant 100%
  • Fluorescence 92%
  • Tumors 82%
  • Surgery 81%
  • Immunotherapy 71%
  18 Scopus citations

• Lipid osteoclastokines regulate breast cancer bone metastasis

  Krzeszinski, J. Y., Schwaid, A. G., Cheng, W. Y., Jin, Z., Gallegos, Z. R., Saghatelian, A. & Wan, Y., Mar 1 2017, In: Endocrinology. 158, 3, p. 477-489 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bone Neoplasms 100%
  • Osteoclasts 84%
  • Lipids 53%
  • Breast Neoplasms 51%
  • Neoplasm Metastasis 50%
  14 Scopus citations

• mTOR Inhibition Subdues Milk Disorder Caused by Maternal VLDLR Loss

  Huynh, H. D., Wei, W. & Wan, Y., Jun 6 2017, In: Cell Reports. 19, 10, p. 2014-2025 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • VLDL receptor 100%
  • Very-Low-Density Lipoprotein 87%
  • Milk 58%
  • Disorder 53%
  • Mothers 39%
  6 Scopus citations

• Nuclear Receptors in Skeletal Homeostasis

  Zuo, H. & Wan, Y., 2017, (Accepted/In press) In: Current Topics in Developmental Biology.

  Research output: Contribution to journal › Article › peer-review

  • Cytoplasmic and Nuclear Receptors 100%
  • Homeostasis 71%
  • Bone and Bones 43%
  • Ligands 34%
  • Osteoporosis 21%
  17 Scopus citations
• 2016

  Gata2 is a rheostat for mesenchymal stem cell fate in male mice

  Li, X., Huynh, H., Zuo, H., Salminen, M. & Wan, Y., Mar 2016, In: Endocrinology. 157, 3, p. 1021-1028 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adipocytes 100%
  • Mesenchymal Stem Cells 94%
  • Osteoblasts 80%
  • Adipogenesis 25%
  • Zinc Fingers 23%
  8 Scopus citations

• Ligand activation of ERRα by cholesterol mediates statin and bisphosphonate effects

  Wei, W., Schwaid, A. G., Wang, X., Wang, X., Chen, S., Chu, Q., Saghatelian, A. & Wan, Y., Mar 8 2016, In: Cell Metabolism. 23, 3, p. 479-491 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Diphosphonates 100%
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 88%
  • Estrogen Receptors 85%
  • Cholesterol 67%
  • Ligands 64%
  117 Scopus citations

• Macrophage PPARγ inhibits GPR132 to mediate the anti-tumor effects of rosiglitazone

  Cheng, W. Y., Huynh, H., Chen, P., Penã-Llopis, S. & Wan, Y., Oct 2016, In: eLife. 5, OCTOBER2016, e18501.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rosiglitazone 100%
  • Peroxisome Proliferator-Activated Receptors 76%
  • Macrophages 44%
  • Peroxisome Proliferator Activated Receptor Agonist 36%
  • Neoplasms 20%
  40 Scopus citations

• MicroRNA Exert Macro Effects on Cancer Bone Metastasis

  Baier, S. R. & Wan, Y., Oct 1 2016, In: Current Osteoporosis Reports. 14, 5, p. 163-169 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Bone Neoplasms 100%
  • MicroRNAs 68%
  • Neoplasm Metastasis 50%
  • Bone and Bones 24%
  • Neoplasms 21%
  4 Scopus citations

• Reply to "pPAR-Î 3 regulates pharmacological but not physiological or pathological osteoclast formation"

  Evans, R. M. & Wan, Y., Nov 8 2016, In: Nature medicine. 22, 11, 1 p.

  Research output: Contribution to journal › Letter › peer-review

• Unique epigenetic gene profiles define human breast cancers with poor prognosis

  Peña-Llopis, S., Wan, Y. & Martinez, E. D., 2016, In: Oncotarget. 7, 52, p. 85819-85831 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epigenomics 100%
  • Breast Neoplasms 73%
  • Genes 46%
  • Breast 19%
  • Nexus 17%
  11 Scopus citations
• 2015

  A Liver-Bone Endocrine Relay by IGFBP1 Promotes Osteoclastogenesis and Mediates FGF21-Induced Bone Resorption

  Wang, X., Wei, W., Krzeszinski, J. Y., Wang, Y. & Wan, Y., Nov 3 2015, In: Cell Metabolism. 22, 5, p. 811-824 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • fibroblast growth factor 21 100%
  • Insulin-Like Growth Factor Binding Protein 1 92%
  • Bone Resorption 69%
  • Osteogenesis 60%
  • Bone and Bones 40%
  112 Scopus citations

• HDAC9 inhibits osteoclastogenesis via mutual suppression of PPARγ/RANKL signaling

  Jin, Z., Wei, W., Huynh, H. & Wan, Y., 2015, In: Molecular Endocrinology. 29, 5, p. 730-738 9 p.

  Research output: Contribution to journal › Article › peer-review

  • RANK Ligand 100%
  • Peroxisome Proliferator-Activated Receptors 90%
  • Nuclear Receptor Co-Repressor 2 89%
  • Bone Resorption 76%
  • Osteogenesis 65%
  59 Scopus citations

• Maternal adiponectin controls milk composition to prevent neonatal inflammation

  Jin, Z., Du, Y., Schwaid, A. G., Asterholm, I. W., Scherer, P. E., Saghatelian, A. & Wan, Y., Apr 1 2015, In: Endocrinology. 156, 4, p. 1504-1513 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Adiponectin 100%
  • Milk 86%
  • Mothers 59%
  • Inflammation 54%
  • Human Mammary Glands 22%
  19 Scopus citations

• Minireview: Nuclear receptor regulation of osteoclast and bone remodeling

  Jin, Z., Li, X. & Wan, Y., 2015, In: Molecular Endocrinology. 29, 2, p. 172-186 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Osteoclasts 100%
  • Bone Remodeling 99%
  • Cytoplasmic and Nuclear Receptors 99%
  • Pycnodysostosis 42%
  • Essential Osteolysis 39%
  32 Scopus citations

• New therapeutic targets for cancer bone metastasis

  Krzeszinski, J. Y. & Wan, Y., 2015, In: Trends in Pharmacological Sciences. 36, 6, p. 360-373 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Bone Neoplasms 100%
  • Thyroid 50%
  • Neoplasm Metastasis 50%
  • Bone and Bones 48%
  • Molecule 28%
  68 Scopus citations

• Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1 self-limitation

  Li, X., Wei, W., Huynh, H., Zuo, H., Wang, X. & Wan, Y., Jul 14 2015, In: eLife. 4, JULY 2015, e07217.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ligases 100%
  • Osteoclasts 94%
  • Ubiquitin 91%
  • Osteogenesis 80%
  • Disorder 78%
  22 Scopus citations

• Sim1 inhibits bone formation by enhancing the sympathetic tone in male mice

  Wang, X., Wei, W., Zinn, A. R. & Wan, Y., Apr 1 2015, In: Endocrinology. 156, 4, p. 1408-1415 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Osteogenesis 100%
  • Bone and Bones 67%
  • Adrenergic Agonists 48%
  • Loss of Function Mutation 42%
  • Sympathetic Nervous System 42%
  3 Scopus citations
• 2014

  FGF-21 and skeletal remodeling during and after lactation in C57BL/6J mice

  Bornstein, S., Brown, S. A., Le, P. T., Wang, X., DeMambro, V., Horowitz, M. C., MacDougald, O., Baron, R., Lotinun, S., Karsenty, G., Wei, W., Ferron, M., Kovacs, C. S., Clemmons, D., Wan, Y. & Rosen, C. J., Sep 1 2014, In: Endocrinology. 155, 9, p. 3516-3526 11 p.

  Research output: Contribution to journal › Article › peer-review

  • fibroblast growth factor 21 100%
  • Lactation 74%
  • Inbred C57BL Mouse 64%
  • Body Composition 22%
  • Cancellous Bone 12%
  54 Scopus citations

• MiR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2

  Krzeszinski, J. Y., Wei, W., Huynh, H., Jin, Z., Wang, X., Chang, T. C., Xie, X. J., He, L., Mangala, L. S., Lopez-Berestein, G., Sood, A. K., Mendell, J. T. & Wan, Y., Aug 28 2014, In: Nature. 512, 7515, p. 431-435 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transforming Growth Factors 100%
  • Osteoporosis 84%
  • Osteogenesis 83%
  • Bone Resorption 77%
  • Osteoclasts 59%
  290 Scopus citations

• Mitochondrial complex i activity suppresses inflammation and enhances bone resorption by shifting macrophage-osteoclast polarization

  Jin, Z., Wei, W., Yang, M., Du, Y. & Wan, Y., Sep 2 2014, In: Cell Metabolism. 20, 3, p. 483-498 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Osteoclasts 100%
  • Bone Resorption 98%
  • Osteopetrosis 92%
  • Fatty Acids 82%
  • Macrophages 67%
  179 Scopus citations

• Orexin regulates bone remodeling via a dominant positive central action and a subordinate negative peripheral action

  Wei, W., Motoike, T., Krzeszinski, J. Y., Jin, Z., Xie, X-J., Dechow, P. C., Yanagisawa, M. & Wan, Y., Jun 3 2014, In: Cell Metabolism. 19, 6, p. 927-940 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Orexins 100%
  • Bone Remodeling 78%
  • Bone and Bones 34%
  • Orexin Receptors 28%
  • Osteogenesis 16%
  30 Scopus citations
• 2013

  Bone marrow mesenchymal stem cells: Fat on and blast off by FGF21

  Wan, Y., Mar 2013, In: International Journal of Biochemistry and Cell Biology. 45, 3, p. 546-549 4 p.

  Research output: Contribution to journal › Short survey › peer-review

  • fibroblast growth factor 21 100%
  • Fat 67%
  • Mesenchymal Stem Cells 61%
  • Disorder 58%
  • Fats 51%
  26 Scopus citations

• HDAC7 inhibits osteoclastogenesis by reversing RANKL-triggered β-catenin switch

  Jin, Z., Wei, W., Dechow, P. C. & Wan, Y., Feb 2013, In: Molecular Endocrinology. 27, 2, p. 325-335 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Catenins 100%
  • Histone Deacetylases 92%
  • Osteogenesis 69%
  • Osteoclasts 46%
  • Bone Resorption 23%
  44 Scopus citations

• IBAT on bone

  Wan, Y., Aug 1 2013, In: Endocrinology. 154, 8, p. 2579-2580 2 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen

  Gautron, L., Rutkowski, J. M., Burton, M. D., Wei, W., Wan, Y. & Elmquist, J. K., Nov 2013, In: Journal of Comparative Neurology. 521, 16, p. 3741-3767 27 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cholinergic Agents 100%
  • Gastrointestinal Tract 92%
  • Spleen 83%
  • Lymphocytes 73%
  • Peyer's Patches 69%
  107 Scopus citations

• Regulation of Bone Resorption by PPARγ

  Wei, W. & Wan, Y., 2013, Translational Endocrinology of Bone. Elsevier Inc., p. 103-122 20 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations
• 2012

  Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ

  Wei, W., Dutchak, P. A., Wang, X., Ding, X., Wang, X., Bookout, A. L., Goetz, R., Mohammadi, M., Gerard, R. D., Dechow, P. C., Mangelsdorf, D. J., Kliewer, S. A. & Wan, Y., Feb 21 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 3143-3148 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • fibroblast growth factor 21 100%
  • Peroxisome Proliferator-Activated Receptors 82%
  • Bone and Bones 40%
  • MASS syndrome 14%
  • Rosiglitazone 10%
  323 Scopus citations

• Macrophage VLDL receptor promotes PAFAH secretion in mother's milk and suppresses systemic inflammation in nursing neonates

  Du, Y., Yang, M., Wei, W., Huynh, H. D., Herz, J., Saghatelian, A. & Wan, Y., 2012, In: Nature communications. 3, 1008.

  Research output: Contribution to journal › Article › peer-review

  • VLDL receptor 100%
  • lipoproteins 90%
  • macrophages 89%
  • Very-Low-Density Lipoprotein 87%
  • secretions 86%
  24 Scopus citations

• Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity

  Du, Y., Yang, M., Lee, S., Behrendt, C. L., Hooper, L. V., Saghatelian, A. & Wan, Y., Jun 2012, In: Genes and Development. 26, 12, p. 1306-1311 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Western Diet 100%
  • Milk 70%
  • Mothers 47%
  • Ceramides 29%
  • Lactation 27%
  43 Scopus citations

• The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

  Zhang, Y., Xie, Y., Berglund, E. D., Colbert Coate, K., He, T. T., Katafuchi, T., Xiao, G., Potthoff, M. J., Wei, W., Wan, Y., Yu, R. T., Evans, R. M., Kliewer, S. A. & Mangelsdorf, D. J., Oct 15 2012, In: eLife. 2012, 1, e00065.

  Research output: Contribution to journal › Article › peer-review

  • fibroblast growth factor 21 100%
  • Growth Hormone 88%
  • Starvation 74%
  • Insulin Derivative 70%
  • Hormone 68%
  290 Scopus citations

• Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake

  Zeve, D., Seo, J., Suh, J. M., Stenesen, D., Tang, W., Berglund, E. D., Wan, Y., Williams, L. J., Lim, A., Martinez, M. J., McKay, R. M., Millay, D. P., Olson, E. N. & Graff, J. M., Apr 4 2012, In: Cell Metabolism. 15, 4, p. 492-504 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Fats 100%
  • Insulin 90%
  • Lipodystrophy 89%
  • Glucose 83%
  • Muscles 80%
  60 Scopus citations
• 2011

  Biphasic and dosage-dependent regulation of osteoclastogenesis by β-catenin

  Wei, W., Zeve, D., Suh, J. M., Wang, X., Du, Y., Zerwekh, J. E., Dechow, P. C., Graff, J. M. & Wan, Y., Dec 2011, In: Molecular and cellular biology. 31, 23, p. 4706-4719 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Catenins 100%
  • Osteogenesis 69%
  • Osteoclasts 46%
  • Osteopetrosis 16%
  • Bone Diseases 12%
  159 Scopus citations

• Osteoclast progenitors reside in the peroxisome proliferator-activated receptor γ-expressing bone marrow cell population

  Wei, W., Zeve, D., Wang, X., Du, Y., Tang, W., Dechow, P. C., Graff, J. M. & Wan, Y., Dec 2011, In: Molecular and cellular biology. 31, 23, p. 4692-4705 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peroxisome Proliferator-Activated Receptors 100%
  • Osteoclasts 85%
  • Bone Marrow Cells 78%
  • Population 32%
  • Bone and Bones 18%
  42 Scopus citations

• Thiazolidinediones on PPARγ: The roles in bone remodeling

  Wei, W. & Wan, Y., 2011, In: PPAR Research. 867180.

  Research output: Contribution to journal › Review article › peer-review

  • Rosiglitazone 100%
  • Thiazolidinediones 83%
  • PPAR gamma 70%
  • Bone Remodeling 65%
  • Insulin Derivative 64%
  38 Scopus citations
• 2010

  Erratum: Pgc1β Mediates PPARγ Activation of Osteoclastogenesis and Rosiglitazone-Induced Bone Loss (Cell Metabolism (2010) 11 (503-516))

  Wei, W., Wang, X., Yang, M., Smith, L. C., Dechow, P. C., Sonoda, J., Evans, R. M. & Wan, Y., Aug 4 2010, In: Cell Metabolism. 12, 2, p. 202 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  1 Scopus citations

• PGC1β mediates PPARγ activation of osteoclastogenesis and rosiglitazone-induced bone loss

  Wei, W., Wang, X., Yang, M., Smith, L. C., Dechow, P. C. & Wan, Y., Jun 9 2010, In: Cell Metabolism. 11, 6, p. 503-516 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Rosiglitazone 100%
  • Peroxisome Proliferator-Activated Receptors 94%
  • Osteogenesis 68%
  • Bone and Bones 46%
  • Osteoclasts 40%
  209 Scopus citations

• PPARγ in bone homeostasis

  Wan, Y., Dec 2010, In: Trends in Endocrinology and Metabolism. 21, 12, p. 722-728 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Peroxisome Proliferator-Activated Receptors 100%
  • Homeostasis 60%
  • Bone and Bones 49%
  • Rosiglitazone 35%
  • Osteogenesis 24%
  115 Scopus citations

• Rosiglitazone activation of PPARg suppresses fractalkine signaling

  Wan, Y. & Evans, R. M., Feb 2010, In: Journal of molecular endocrinology. 44, 2, p. 135-142 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Chemokine CX3CL1 100%
  • Rosiglitazone 86%
  • Peroxisome Proliferator-Activated Receptors 81%
  • CX3C Chemokine Receptor 1 16%
  • Thiazolidinediones 12%
  23 Scopus citations
• 2007

  Maternal PPARγ protects nursing neonates by suppressing the production of inflammatory milk

  Wan, Y., Saghatelian, A., Chong, L. W., Zhang, C. L., Cravatt, B. F. & Evans, R. M., Aug 1 2007, In: Genes and Development. 21, 15, p. 1895-1908 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Peroxisome Proliferator-Activated Receptors 100%
  • Milk 77%
  • Nursing 68%
  • Human Mammary Glands 54%
  • Mothers 52%
  92 Scopus citations