Pharmacology - Zhang Lab

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Ligands Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Dimerization Medicine & Life Sciences
GTPase-Activating Proteins Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Chemical activation Chemical Compounds
Semaphorins Medicine & Life Sciences
Cell Surface Receptors Medicine & Life Sciences

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Profiles

Research Output 2001 2019

Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands

Li, J., Shang, G., Chen, Y. J., Brautigam, C. A., Liou, J., Zhang, X. & Bai, X. C., Sep 2019, In : eLife. 8, e47650.

Research output: Contribution to journalArticle

Open Access
Chemical activation
Ligands
Glial Cell Line-Derived Neurotrophic Factor
Phosphorylation
Dimerization
13 Citations (Scopus)

Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP

Shang, G., Zhang, C., Chen, Z., Bai, X. & Zhang, X., Mar 21 2019, In : Nature. 567, 7748, p. 389-393 5 p.

Research output: Contribution to journalLetter

Ligands
Chickens
Cryoelectron Microscopy
Interferon Type I
Endoplasmic Reticulum

Effector Specificity Mechanisms of Rab35 GTPase

Kuo, Y. C. & Zhang, X., May 7 2019, In : Structure. 27, 5, p. 725-727 3 p.

Research output: Contribution to journalShort survey

GTP Phosphohydrolases