Research Output

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Review article
2020

Immortalized normal human lung epithelial cell models for studying lung cancer biology

Sato, M., Shay, J. W. & Minna, J. D., 2020, (Accepted/In press) In : Respiratory Investigation.

Research output: Contribution to journalReview article

Karyopherins and condensates

Springhower, C. E., Rosen, M. K. & Chook, Y. M., Jun 2020, In : Current Opinion in Cell Biology. 64, p. 112-123 12 p.

Research output: Contribution to journalReview article

Open Access

Location, Location, Location: Compartmentalization of NAD+ Synthesis and Functions in Mammalian Cells

Cambronne, X. A. & Kraus, W. L., 2020, (Accepted/In press) In : Trends in biochemical sciences.

Research output: Contribution to journalReview article

New Approaches to SCLC Therapy: From the Laboratory to the Clinic

Poirier, J. T., George, J., Owonikoko, T. K., Berns, A., Brambilla, E., Byers, L. A., Carbone, D., Chen, H. J., Christensen, C. L., Dive, C., Farago, A. F., Govindan, R., Hann, C., Hellmann, M. D., Horn, L., Johnson, J. E., Ju, Y. S., Kang, S., Krasnow, M., Lee, J. & 27 others, Lee, S. H., Lehman, J., Lok, B., Lovly, C., MacPherson, D., McFadden, D., Minna, J., Oser, M., Park, K., Park, K. S., Pommier, Y., Quaranta, V., Ready, N., Sage, J., Scagliotti, G., Sos, M. L., Sutherland, K. D., Travis, W. D., Vakoc, C. R., Wait, S. J., Wistuba, I., Wong, K. K., Zhang, H., Daigneault, J., Wiens, J., Rudin, C. M. & Oliver, T. G., Apr 2020, In : Journal of Thoracic Oncology. 15, 4, p. 520-540 21 p.

Research output: Contribution to journalReview article

1 Scopus citations

Pancreatic cancer stroma: an update on therapeutic targeting strategies

Hosein, A. N., Brekken, R. A. & Maitra, A., Aug 1 2020, In : Nature Reviews Gastroenterology and Hepatology. 17, 8, p. 487-505 19 p.

Research output: Contribution to journalReview article

PARPs and ADP-ribosylation: 60 years on

Kraus, W. L., Mar 1 2020, In : Genes and Development. 34, 5, p. 251-253 3 p.

Research output: Contribution to journalReview article

Open Access

PARPs and ADP-ribosylation in RNA biology: From RNA expression and processing to protein translation and proteostasis

Kim, D. S., Challa, S., Jones, A. & Kraus, W. L., Mar 1 2020, In : Genes and Development. 34, 5, p. 302-320 19 p.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Spatial compartmentalization of lipid droplet biogenesis

Henne, M., Goodman, J. M. & Hariri, H., Jan 1 2020, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1865, 1, 158499.

Research output: Contribution to journalReview article

2 Scopus citations

Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway

Zhang, X., Bai, X. C. & Chen, Z. J., Jul 14 2020, In : Immunity. 53, 1, p. 43-53 11 p.

Research output: Contribution to journalReview article

The 10th Oligonucleotide Therapy Approved: Golodirsen for Duchenne Muscular Dystrophy

Aartsma-Rus, A. & Corey, D. R., Apr 2020, In : Nucleic Acid Therapeutics. 30, 2, p. 67-70 4 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

TIMs, TAMs, and PS- antibody targeting: Implications for cancer immunotherapy

Dayoub, A. S. & Brekken, R. A., Feb 22 2020, In : Cell Communication and Signaling. 18, 1, 29.

Research output: Contribution to journalReview article

Open Access
2019

A Dozen Years of Discovery: Insights into the Physiology and Pharmacology of FGF21

Kliewer, S. A. & Mangelsdorf, D. J., Feb 5 2019, In : Cell Metabolism. 29, 2, p. 246-253 8 p.

Research output: Contribution to journalReview article

26 Scopus citations

Artificial intelligence in lung cancer pathology image analysis

Wang, S., Yang, D. M., Rong, R., Zhan, X., Fujimoto, J., Liu, H., Minna, J., Wistuba, I. I., Xie, Y. & Xiao, G., Nov 2019, In : Cancers. 11, 11, 1673.

Research output: Contribution to journalReview article

Open Access
4 Scopus citations

Behind the Wheel of Epithelial Plasticity in KRAS-Driven Cancers

Arner, E. N., Du, W. & Brekken, R. A., Oct 11 2019, In : Frontiers in Oncology. 9, 1049.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Getting a grip on adhesion: Cadherin switching and collagen signaling

Huang, H., Wright, S., Zhang, J. & Brekken, R. A., Jan 1 2019, In : Biochimica et Biophysica Acta - Molecular Cell Research.

Research output: Contribution to journalReview article

4 Scopus citations

Molecular determinants for the polarization of macrophage and osteoclast

Yang, D. & Wan, Y., Sep 1 2019, In : Seminars in Immunopathology. 41, 5, p. 551-563 13 p.

Research output: Contribution to journalReview article

3 Scopus citations

PARP-1 and its associated nucleases in DNA damage response

Wang, Y., Luo, W. & Wang, Y., Sep 2019, In : DNA repair. 81, 102651.

Research output: Contribution to journalReview article

8 Scopus citations
Open Access

Thinking outside of the cell: Secreted protein kinases in bacteria, parasites, and mammals

Park, B. C., Reese, M. & Tagliabracci, V. S., Jun 2019, In : IUBMB life. 71, 6, p. 749-759 11 p.

Research output: Contribution to journalReview article

1 Scopus citations
2018

Activation mechanisms of the Hippo kinase signaling cascade

Bae, S. J. & Luo, X., Aug 29 2018, In : Bioscience Reports. 38, 4, BSR20171469.

Research output: Contribution to journalReview article

12 Scopus citations

Axon formation, extension, and navigation: only a neuroscience phenomenon?

Rich, S. K. & Terman, J. R., Dec 1 2018, In : Current Opinion in Neurobiology. 53, p. 174-182 9 p.

Research output: Contribution to journalReview article

3 Scopus citations

Cooperativity Principles in Self-Assembled Nanomedicine

Li, Y., Wang, Y., Huang, G. & Gao, J., Jun 13 2018, In : Chemical Reviews. 118, 11, p. 5359-5391 33 p.

Research output: Contribution to journalReview article

47 Scopus citations

Does Axl have potential as a therapeutic target in pancreatic cancer?

Du, W. & Brekken, R. A., Nov 2 2018, In : Expert Opinion on Therapeutic Targets. 22, 11, p. 955-966 12 p.

Research output: Contribution to journalReview article

6 Scopus citations

Emerging Contributions of Cancer/Testis Antigens to Neoplastic Behaviors

Gibbs, Z. A. & Whitehurst, A. W., Oct 1 2018, In : Trends in Cancer. 4, 10, p. 701-712 12 p.

Research output: Contribution to journalReview article

7 Scopus citations

Karyopherins in cancer

Çağatay, T. & Chook, Y. M., Jun 1 2018, In : Current Opinion in Cell Biology. 52, p. 30-42 13 p.

Research output: Contribution to journalReview article

14 Scopus citations

Leptin and brain-adipose crosstalks

Caron, A., Lee, S., Elmquist, J. K. & Gautron, L., Feb 16 2018, In : Nature Reviews Neuroscience. 19, 3, p. 153-165 13 p.

Research output: Contribution to journalReview article

40 Scopus citations

Modulators of redox metabolism in head and neck cancer

Chen, X., Mims, J., Huang, X., Singh, N., Motea, E., Planchon, S. M., Beg, M. S., Tsang, A. W., Porosnicu, M., Kemp, M. L., Boothman, D. A. & Furdui, C. M., Dec 1 2018, In : Antioxidants and Redox Signaling. 29, 16, p. 1660-1690 31 p.

Research output: Contribution to journalReview article

5 Scopus citations

Optical molecular imaging for tumor detection and image-guided surgery

Wang, C., Wang, Z., Zhao, T., Li, Y., Huang, G., Sumer, B. D. & Gao, J., Mar 1 2018, In : Biomaterials. 157, p. 62-75 14 p.

Research output: Contribution to journalReview article

48 Scopus citations

Polyamine function in archaea and bacteria

Michael, A. J., Nov 30 2018, In : Journal of Biological Chemistry. 293, 48, p. 18693-18701 9 p.

Research output: Contribution to journalReview article

21 Scopus citations

Polyamines in protozoan pathogens

Phillips, M. A., Nov 30 2018, In : Journal of Biological Chemistry. 293, 48, p. 18746-18756 11 p.

Research output: Contribution to journalReview article

8 Scopus citations
12 Scopus citations

The assembly of lipid droplets and their roles in challenged cells

Henne, W. M., Reese, M. L. & Goodman, J. M., Jun 15 2018, In : EMBO Journal. 37, 12, e98947.

Research output: Contribution to journalReview article

43 Scopus citations

WNK pathways in cancer signaling networks 06 Biological Sciences 0601 Biochemistry and Cell Biology

Gallolu Kankanamalage, S., Karra, A. S. & Cobb, M. H., Nov 3 2018, In : Cell Communication and Signaling. 16, 1, 72.

Research output: Contribution to journalReview article

7 Scopus citations
2017

A cascade of multiple proteins and lipids catalyzes membrane fusion

Wickner, W. & Rizo-Rey, J., Mar 15 2017, In : Molecular Biology of the Cell. 28, 6, p. 707-711 5 p.

Research output: Contribution to journalReview article

36 Scopus citations

Bile acids and colon cancer: Is FXR the solution of the conundrum?

Gadaleta, R. M., Garcia-Irigoyen, O. & Moschetta, A., Aug 1 2017, In : Molecular Aspects of Medicine. 56, p. 66-74 9 p.

Research output: Contribution to journalReview article

26 Scopus citations

Brain nuclear receptors and body weight regulation

Xu, Y., O'Malley, B. W. & Elmquist, J. K., Apr 3 2017, In : Journal of Clinical Investigation. 127, 4, p. 1172-1180 9 p.

Research output: Contribution to journalReview article

7 Scopus citations

Comprehensive evaluation of published gene expression prognostic signatures for biomarker-based lung cancer clinical studies

Tang, H., Wang, S., Xiao, G., Schiller, J., Papadimitrakopoulou, V., Minna, J., Wistuba, I. I. & Xie, Y., Apr 1 2017, In : Annals of Oncology. 28, 4, p. 733-740 8 p., mdw683.

Research output: Contribution to journalReview article

22 Scopus citations

Evolution of biosynthetic diversity

Michael, A. J., Jul 15 2017, In : Biochemical Journal. 474, 14, p. 2277-2299 23 p.

Research output: Contribution to journalReview article

16 Scopus citations

Extracellular Matrix Induction of Intracellular Reactive Oxygen Species

Huang, H., Du, W. & Brekken, R. A., Oct 20 2017, In : Antioxidants and Redox Signaling. 27, 12, p. 774-784 11 p.

Research output: Contribution to journalReview article

8 Scopus citations

From top to bottom: Midkine and pleiotrophin as emerging players in immune regulation

Sorrelle, N., Dominguez, A. T. A. & Brekken, R. A., Aug 1 2017, In : Journal of Leukocyte Biology. 102, 2, p. 277-286 10 p.

Research output: Contribution to journalReview article

10 Scopus citations

Involvement of Brd4 in different steps of the papillomavirus life cycle

Iftner, T., Haedicke-Jarboui, J., Wu, S. Y. & Chiang, C. M., Mar 2 2017, In : Virus Research. 231, p. 76-82 7 p.

Research output: Contribution to journalReview article

23 Scopus citations

Mechanisms of the amplifying pathway of insulin secretion in the β cell

Kalwat, M. A. & Cobb, M. H., Nov 2017, In : Pharmacology and Therapeutics. 179, p. 17-30 14 p.

Research output: Contribution to journalReview article

20 Scopus citations

Nuclear receptors: Emerging drug targets for parasitic diseases

Wang, Z., Schaffer, N. E., Kliewer, S. A. & Mangelsdorf, D. J., Apr 3 2017, In : Journal of Clinical Investigation. 127, 4, p. 1165-1171 7 p.

Research output: Contribution to journalReview article

6 Scopus citations

Parps and adp-ribosylation: Recent advances linking molecular functions to biological outcomes

Gupte, R., Liu, Z. & Kraus, W. L., Jan 15 2017, In : Genes and Development. 31, 2, p. 101-126 26 p.

Research output: Contribution to journalReview article

163 Scopus citations

Small-cell lung cancer: What we know, what we need to know and the path forward

Gazdar, A. F., Bunn, P. A. & Minna, J. D., Dec 1 2017, In : Nature Reviews Cancer. 17, 12, p. 725-737 13 p.

Research output: Contribution to journalReview article

141 Scopus citations

The hypothalamic regulation of metabolic adaptations to exercise

Fujikawa, T., Castorena, C. M., Lee, S. & Elmquist, J. K., Oct 1 2017, In : Journal of Neuroendocrinology. 29, 10, e12533.

Research output: Contribution to journalReview article

6 Scopus citations
2016

Actin filaments—A target for redox regulation

Wilson, C., Terman, J. R., González-Billault, C. & Ahmed, G., Oct 1 2016, In : Cytoskeleton. 73, 10, p. 577-595 19 p.

Research output: Contribution to journalReview article

30 Scopus citations

Biosynthesis of polyamines and polyamine-containing molecules

Michael, A. J., 2016, In : Biochemical Journal. 473, 15, p. 2315-2329 15 p.

Research output: Contribution to journalReview article

48 Scopus citations

Hypertension: The missing WNKs

Dbouk, H. A., Huang, C. L. & Cobb, M. H., Jul 1 2016, In : American Journal of Physiology - Renal Physiology. 311, 1, p. F16-F27

Research output: Contribution to journalReview article

7 Scopus citations

Is hepatic lipogenesis fundamental for NAFLD/NASH? A focus on the nuclear receptor coactivator PGC-1β

Ducheix, S., Vegliante, M. C., Villani, G., Napoli, N., Sabbà, C. & Moschetta, A., Oct 1 2016, In : Cellular and Molecular Life Sciences. 73, 20, p. 3809-3822 14 p.

Research output: Contribution to journalReview article

6 Scopus citations