Research output per year
Research output per year
- 1 - 50 out of 137 results
Search results
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2024
Mimicking Protein Kinase C Phosphorylation Inhibits Arc/Arg3.1 Palmitoylation and Its Interaction with Nucleic Acids
Barylko, B., Taylor, C. A., Wang, J., Earnest, S., Stippec, S., Binns, D. D., Brautigam, C. A., Jameson, D. M., DeMartino, G. N., Cobb, M. H. & Albanesi, J. P., Jan 2024, In: International journal of molecular sciences. 25, 2, 780.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Ηigh-resolution structure of mammalian PI31–20S proteasome complex reveals mechanism of proteasome inhibition
Hsu, H. C., Wang, J., Kjellgren, A., Li, H. & DeMartino, G. N., Jul 2023, In: Journal of Biological Chemistry. 299, 7, 104862.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2022
2022 Herbert Tabor Early Career Investigator Awards: Call for nominations
Farabaugh, K. T., Toker, A. & DeMartino, G., Oct 2022, In: Journal of Biological Chemistry. 298, 10, 102516.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Highly conserved shifts in ubiquitin-proteasome system (UPS) activity drive mitochondrial remodeling during quiescence
Yue, S., Wang, L., DeMartino, G. N., Zhao, F. Z., Liu, Y. & Sieber, M. H., Dec 2022, In: Nature communications. 13, 1, 4462.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2020
Palmitoylated Proteins in Dendritic Spine Remodeling
Albanesi, J. P., Barylko, B., DeMartino, G. N. & Jameson, D. M., Jun 16 2020, In: Frontiers in Synaptic Neuroscience. 12, 22.Research output: Contribution to journal › Review article › peer-review
Open Access9 Scopus citations -
2019
2019 Herbert Tabor Young Investigator Awards: Call for nominations
DeMartino, G. N., 2019, In: Journal of Biological Chemistry. 293, 37, p. 14571 1 p.Research output: Contribution to journal › Editorial › peer-review
Open Access1 Scopus citations -
2020 Herbert Tabor Early Career Investigator Awards: Call for nominations
Gierasch, L. M. & DeMartino, G. N., Sep 6 2019, In: Journal of Biological Chemistry. 294, 36, p. 13526 1 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Celebrating science’s next generation
Gierasch, L. M. & De Martino, G., Mar 1 2019, In: Journal of Biological Chemistry. 294, 9, p. 3323-3324 2 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2018
Introduction to the Thematic Minireview Series: Autophagy
DeMartino, G. N., Apr 13 2018, In: Journal of Biological Chemistry. 293, 15, p. 5384-5385 2 p.Research output: Contribution to journal › Review article › peer-review
Open Access9 Scopus citations -
The herbert tabor young investigator awards: Meet the awardees!
Gierasch, L. M. & DeMartino, G., Mar 2 2018, In: Journal of Biological Chemistry. 293, 9, p. 3468-3469 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access3 Scopus citations -
2017
The Herbert Tabor Best Paper Awards: Celebrating young authors who contribute top content to JBC
Gierasch, L. M. & DeMartino, G., Oct 13 2017, In: Journal of Biological Chemistry. 292, 41, p. 17576 1 p.Research output: Contribution to journal › Editorial › peer-review
Open Access5 Scopus citations -
2016
The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs
Signer, R. A. J., Qi, L., Zhao, Z., Thompson, D., Sigova, A. A., Fan, Z. P., Demartino, G. N., Young, R. A., Sonenberg, N. & Morrison, S. J., Aug 1 2016, In: Genes and Development. 30, 15, p. 1698-1703 6 p.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
2014
Molecular and cellular roles of PI31 (PSMF1) protein in regulation of proteasome function
Li, X., Thompson, D., Kumar, B. & DeMartino, G. N., Jun 20 2014, In: Journal of Biological Chemistry. 289, 25, p. 17392-17405 14 p.Research output: Contribution to journal › Article › peer-review
49 Scopus citations -
2013
ATP binding by proteasomal ATPases regulates cellular assembly and substrate-induced functions of the 26 S proteasome
Kim, Y. C., Li, X., Thompson, D. & Demartino, G. N., Feb 1 2013, In: Journal of Biological Chemistry. 288, 5, p. 3334-3345 12 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
2012
Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95
Tsai, N. P., Wilkerson, J. R., Guo, W., Maksimova, M. A., Demartino, G. N., Cowan, C. W. & Huber, K. M., Dec 21 2012, In: Cell. 151, 7, p. 1581-1594 14 p.Research output: Contribution to journal › Article › peer-review
219 Scopus citations -
Reconstitution of PA700, the 19S regulatory particle, from purified precursor complexes
Demartino, G. N., 2012, Ubiquitin Family Modifiers and the Proteasome: Reviews and Protocols. Dohmen, J. & Scheffner, M. (eds.). p. 443-452 10 p. (Methods in Molecular Biology; vol. 832).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
2011
C termini of proteasomal ATpases play nonequivalent roles in cellular assembly of mammalian 26 S proteasome
Kim, Y. C. & DeMartino, G. N., Jul 29 2011, In: Journal of Biological Chemistry. 286, 30, p. 26652-26666 15 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
2010
Accelerated formation of α-synuclein oligomers by concerted action of the 20s proteasome and familial parkinson mutations
Lewis, K. A., Yaeger, A., Demartino, G. N. & Thomas, P. J., Feb 2010, In: Journal of Bioenergetics and Biomembranes. 42, 1, p. 85-95 11 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
PSMB8 encoding the β5i proteasome subunit is mutated in joint contractures, muscle atrophy, microcytic anemia, and panniculitis-induced lipodystrophy syndrome
Agarwal, A. K., Xing, C., Demartino, G. N., Mizrachi, D., Hernandez, M. D., Sousa, A. B., Martínez De Villarreal, L., Dos Santos, H. G. & Garg, A., Dec 10 2010, In: American Journal of Human Genetics. 87, 6, p. 866-872 7 p.Research output: Contribution to journal › Article › peer-review
266 Scopus citations -
The C terminus of Rpt3, an ATPase subunit of PA700 (19 S) regulatory complex, is essential for 26 S proteasome assembly but not for activation
Kumar, B., Kim, Y. C. & DeMartino, G. N., Dec 10 2010, In: Journal of Biological Chemistry. 285, 50, p. 39523-39535 13 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
2009
PUPylation: something old, something new, something borrowed, something Glu
DeMartino, G. N., Apr 2009, In: Trends in biochemical sciences. 34, 4, p. 155-158 4 p.Research output: Contribution to journal › Short survey › peer-review
7 Scopus citations -
Regulated endoplasmic reticulum-associated degradation of a polytopic protein: p97 recruits proteasomes to Insig-1 before extraction from membranes
Ikeda, Y., DeMartino, G. N., Brown, M. S., Lee, J. N., Goldstein, J. L. & Ye, J., Dec 11 2009, In: Journal of Biological Chemistry. 284, 50, p. 34889-34900 12 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Regulation of the proteasome by neuronal activity and calcium/calmodulin-dependent protein kinase II
Djakovic, S. N., Schwarz, L. A., Barylko, B., DeMartino, G. N. & Patrick, G. N., Sep 25 2009, In: Journal of Biological Chemistry. 284, 39, p. 26655-26665 11 p.Research output: Contribution to journal › Article › peer-review
198 Scopus citations -
Subcomplexes of PA700, the 19 S regulator of the 26 S proteasome, reveal relative roles of AAA subunits in 26 S proteasome assembly and activation and ATPase activity
Thompson, D., Hakala, K. & DeMartino, G. N., Sep 11 2009, In: Journal of Biological Chemistry. 284, 37, p. 24891-24903 13 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
Variably modulated gating of the 26S proteasome by ATP and polyubiquitin
Li, X. & DeMartino, G. N., Aug 1 2009, In: Biochemical Journal. 421, 3, p. 397-404 8 p.Research output: Contribution to journal › Article › peer-review
48 Scopus citations -
2008
Differential roles of the COOH termini of AAA subunits of PA700 (19 S regulator) in asymmetric assembly and Activation of the 26 S proteasome
Gillette, T. G., Kumar, B., Thompson, D., Slaughter, C. A. & DeMartino, G. N., Nov 14 2008, In: Journal of Biological Chemistry. 283, 46, p. 31813-31822 10 p.Research output: Contribution to journal › Article › peer-review
130 Scopus citations -
JAMP optimizes ERAD to protect cells from unfolded proteins
Tcherpakov, M., Broday, L., Delaunay, A., Kadoya, T., Khurana, A., Erdjument-Bromage, H., Tempst, P., Qiu, X. B., Demartino, G. N. & Ronai, Z., Nov 2008, In: Molecular biology of the cell. 19, 11, p. 5019-5028 10 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome
Koulich, E., Li, X. & DeMartino, G. N., Mar 2008, In: Molecular biology of the cell. 19, 3, p. 1072-1082 11 p.Research output: Contribution to journal › Article › peer-review
180 Scopus citations -
2007
Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response
Gerdes, J. M., Liu, Y., Zaghloul, N. A., Leitch, C. C., Lawson, S. S., Kato, M., Beachy, P. A., Beales, P. L., DeMartino, G. N., Fisher, S., Badano, J. L. & Katsanis, N., Nov 2007, In: Nature genetics. 39, 11, p. 1350-1360 11 p.Research output: Contribution to journal › Article › peer-review
337 Scopus citations -
Proteasome Regulator, PA700 (19S Regulatory Particle)
DeMartino, G. N. & Wojcik, C., Dec 14 2007, Protein Degradation. Wiley-VCH Verlag GmbH & Co. KGaA, Vol. 1. p. 288-316 29 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Proteasomes: Machines for All Reasons
DeMartino, G. N. & Gillette, T. G., May 18 2007, In: Cell. 129, 4, p. 659-662 4 p.Research output: Contribution to journal › Short survey › peer-review
198 Scopus citations -
Real-Time Fluorescence Detection of ERAD Substrate Retrotranslocation in a Mammalian In Vitro System
Wahlman, J., DeMartino, G. N., Skach, W. R., Bulleid, N. J., Brodsky, J. L. & Johnson, AE., Jun 1 2007, In: Cell. 129, 5, p. 943-955 13 p.Research output: Contribution to journal › Article › peer-review
113 Scopus citations -
2006
ATP Binding and ATP Hydrolysis Play Distinct Roles in the Function of 26S Proteasome
Liu, C. W., Li, X., Thompson, D., Wooding, K., Chang, T. L., Tang, Z., Yu, H., Thomas, P. J. & DeMartino, G. N., Oct 6 2006, In: Molecular cell. 24, 1, p. 39-50 12 p.Research output: Contribution to journal › Article › peer-review
149 Scopus citations -
Modification of Cul1 regulates its association with proteasomal subunits
Bloom, J., Peschiaroli, A., DeMartino, G. & Pagano, M., Apr 28 2006, In: Cell Division. 1, 5.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1
Yao, T., Song, L., Xu, W., DeMartino, G. N., Florens, L., Swanson, S. K., Washburn, M. P., Conaway, R. C., Conaway, J. W. & Cohen, R. E., Sep 2006, In: Nature cell biology. 8, 9, p. 994-1002 9 p.Research output: Contribution to journal › Article › peer-review
278 Scopus citations -
Valosin-containing protein (p97) is a regulator of endoplasmic reticulum stress and of the degradation of N-end rule and ubiquitin-fusion degradation pathway substrates in mammalian cells
Wójcik, C., Rowicka, M., Kudlicki, A., Nowis, D., McConnell, E., Kujawa, M. & DeMartino, G. N., Nov 2006, In: Molecular biology of the cell. 17, 11, p. 4606-4618 13 p.Research output: Contribution to journal › Article › peer-review
Open Access157 Scopus citations -
2005
A precipitating role for truncated α-synuclein and the proteasome in α-synuclein aggregation: Implications for pathogenesis of parkinson disease
Liu, C. W., Giasson, B. I., Lewis, K. A., Lee, V. M., DeMartino, G. N. & Thomas, P. J., Jun 17 2005, In: Journal of Biological Chemistry. 280, 24, p. 22670-22678 9 p.Research output: Contribution to journal › Article › peer-review
228 Scopus citations -
Modulation of gene expression by RNAi.
Wójcik, C., Fabunmi, R. & DeMartino, G. N., 2005, In: Methods in molecular medicine. 108, p. 381-393 13 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Proteasome Regulator, PA700 (19S Regulatory Particle)
Demartino, G. N. & Wojcik, C., Nov 18 2005, Protein Degradation: Ubiquitin and the Chemistry of Life. Wiley-VCH Verlag GmbH & Co. KGaA, Vol. 1. p. 288-316 29 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
3 Scopus citations -
Purification of PA700, the 19S regulatory complex of the 26S proteasome
DeMartino, G. N., 2005, In: Methods in Enzymology. 398, p. 295-306 12 p.Research output: Contribution to journal › Review article › peer-review
25 Scopus citations -
Recognition and processing of misfolded proteins by PA700, the 19S regulatory complex of the 26S proteasome.
Liu, C. W., Strickland, E., Demartino, G. N. & Thomas, P. J., 2005, In: Methods in molecular biology (Clifton, N.J.). 301, p. 71-81 11 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
2004
Lewy-body formation is an aggresome-related process: A hypothesis
Olanow, C. W., Perl, D. P., DeMartino, G. N. & McNaught, K. S. P., Aug 1 2004, In: Lancet Neurology. 3, 8, p. 496-503 8 p.Research output: Contribution to journal › Comment/debate › peer-review
260 Scopus citations -
Proteasome inhibition: mechanism of action.
DeMartino, G. N., Nov 2004, In: Journal of the National Comprehensive Cancer Network : JNCCN. 2 Suppl 4, p. S5-9Research output: Contribution to journal › Review article › peer-review
4 Scopus citations -
RNA interference of valosin-containing protein (VCP/p97) reveals multiple cellular roles linked to ubiquitin/proteasome-dependent proteolysis
Wójcik, C., Yano, M. & DeMartino, G. N., Jan 15 2004, In: Journal of cell science. 117, 2, p. 281-292 12 p.Research output: Contribution to journal › Article › peer-review
211 Scopus citations -
Uncoupling retro-translocation and degradation in the ER-associated degradation of a soluble protein
Lee, R. J., Liu, C. W., Harty, C., McCracken, A. A., Latterich, M., Römisch, K., DeMartino, G. N., Thomas, P. J. & Brodsky, J. L., Jun 2 2004, In: EMBO Journal. 23, 11, p. 2206-2215 10 p.Research output: Contribution to journal › Article › peer-review
Open Access101 Scopus citations -
Varshavsky's contributions [3]
Baumeister, W., Bachmair, A., Chau, V., Cohen, R., Coffino, P., Demartino, G., Deshaies, R., Dohmen, J., Emr, S., Finley, D., Hampton, R., Hill, C., Hochstrasser, M., Huber, R., Jackson, P., Jentsch, S., Johnson, E., Kwon, Y. T., Pagano, M., Pickart, C., & 9 others, Nov 19 2004, In: Science. 306, 5700, p. 1290-1292 3 p.Research output: Contribution to journal › Letter › peer-review
Open Access3 Scopus citations -
2003
Aggregate formation in the spinal cord of mutant SOD1 transgenic mice is reversible and mediated by proteasomes
Puttaparthi, K., Wojcik, C., Rajendran, B., DeMartino, G. N. & Elliott, J. L., Nov 2003, In: Journal of Neurochemistry. 87, 4, p. 851-860 10 p.Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
Endoproteolytic activity of the proteasome
Liu, C. W., Corboy, M. J., DeMartino, G. N. & Thomas, P. J., Jan 17 2003, In: Science. 299, 5605, p. 408-411 4 p.Research output: Contribution to journal › Article › peer-review
359 Scopus citations -
Intracellular localization of proteasomes
Wójcik, C. & DeMartino, G. N., May 1 2003, In: International Journal of Biochemistry and Cell Biology. 35, 5, p. 579-589 11 p.Research output: Contribution to journal › Review article › peer-review
296 Scopus citations -
Proteasome-mediated degradation of p21 via N-terminal ubiquitinylation
Bloom, J., Amador, V., Bartolini, F., DeMartino, G. & Pagano, M., Oct 3 2003, In: Cell. 115, 1, p. 71-82 12 p.Research output: Contribution to journal › Article › peer-review
270 Scopus citations