Physiology - Division C

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Activation-dependent cumulative depletions of extracellular free calcium in guinea pig atrium measured with antipyrylazo III and tetramethylmurexide

Hilgemann, D. W., Delay, M. J. & Langer, G. A., Jan 1 1983, In : Circulation research. 53, 6, p. 779-793 15 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

A micropeptide encoded by a putative long noncoding RNA regulates muscle performance

Anderson, D. M., Anderson, K. M., Chang, C. L., Makarewich, C. A., Nelson, B. R., McAnally, J. R., Kasaragod, P., Shelton, J. M., Liou, J., Bassel-Duby, R. & Olson, E. N., Feb 12 2015, In : Cell. 160, 4, p. 595-606 12 p.

Research output: Contribution to journalArticle

465 Scopus citations

Analysis of Phosphatidylinositol Transfer at ER-PM Junctions in Receptor-Stimulated Live Cells

Chang, C. L. & Liou, J., Jan 1 2019, In : Methods in molecular biology (Clifton, N.J.). 1949, p. 1-11 11 p.

Research output: Contribution to journalArticle

Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels

Zaika, O., Lara, L. S., Gamper, N., Hilgemann, D. W., Jaffe, D. B. & Shapiro, M. S., Aug 1 2006, In : Journal of Physiology. 575, 1, p. 49-67 19 p.

Research output: Contribution to journalArticle

69 Scopus citations
13 Scopus citations

Ca-dependent nonsecretory vesicle fusion in a secretory cell

Wang, T. M. & Hilgemann, D. W., Jul 2008, In : Journal of General Physiology. 132, 1, p. 51-65 15 p.

Research output: Contribution to journalArticle

19 Scopus citations

Cardiac Na+ ‐Ca2+ Exchange System in Giant Membrane Patches

Hilgemann, D. W., Collins, A., Cash, D. P. & Nagel, G. A., Dec 1991, In : Annals of the New York Academy of Sciences. 639, 1, p. 126-139 14 p.

Research output: Contribution to journalArticle

35 Scopus citations

Caspase-mediated Cleavage of Hematopoietic Progenitor Kinase 1 (HPK1) Converts an Activator of NFκB into an Inhibitor of NFκB

Arnold, R., Liou, J., Drexler, H. C. A., Weiss, A. & Kiefer, F., May 4 2001, In : Journal of Biological Chemistry. 276, 18, p. 14675-14684 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

Channel-like function of the Na,K pump probed at microsecond resolution in giant membrane patches

Hilgemann, D. W., Jan 1 1994, In : Science. 263, 5152, p. 1429-1432 4 p.

Research output: Contribution to journalArticle

152 Scopus citations

Charge movement during Na+ translocation by native and cloned cardiac Na+/Ca2+ exchanger

Hilgemann, D. W., Nicoll, D. A. & Philipson, K. D., Jan 1 1991, In : Nature. 352, 6337, p. 715-718 4 p.

Research output: Contribution to journalArticle

168 Scopus citations

Cloning, expression, and characterization of the squid Na+-Ca2+ exchanger (NCX-SQ1)

He, Z., Tong, Q., Quednau, B. D., Philipson, K. D. & Hilgemann, D. W., Jun 1 1998, In : Journal of General Physiology. 111, 6, p. 857-873 17 p.

Research output: Contribution to journalArticle

43 Scopus citations

Cloning and characterization of a novel Mg2+/H+ exchanger

Shaul, O., Hilgemann, D. W., De-Almeida-Engler, J., Van Montagu, M., Inzé, D. & Galili, G., Jul 15 1999, In : EMBO Journal. 18, 14, p. 3973-3980 8 p.

Research output: Contribution to journalArticle

178 Scopus citations

Control of cardiac contraction by sodium: Promises, reckonings, and new beginnings

Hilgemann, D. W., Jan 2020, In : Cell Calcium. 85, 102129.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Cortical actin contributes to spatial organization of ER-PM junctions

Hsieh, T. S., Chen, Y. J., Chang, C. L., Lee, W. R. & Liou, J., Nov 7 2017, In : Molecular Biology of the Cell. 28, 23, p. 3171-3180 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands

Li, J., Shang, G., Chen, Y. J., Brautigam, C. A., Liou, J., Zhang, X. & Bai, X. C., Sep 2019, In : eLife. 8, e47650.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gβγ

Huang, C. L., Feng, S. & Hilgemann, D. W., Feb 19 1998, In : Nature. 391, 6669, p. 803-806 4 p.

Research output: Contribution to journalArticle

693 Scopus citations

Do phosphatidylinositides modulate vertebrate phototransduction?

Womack, K. B., Gordon, S. E., He, F., Wensel, T. G., Lu, C. C. & Hilgemann, D. W., Apr 15 2000, In : Journal of Neuroscience. 20, 8, p. 2792-2799 8 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

Dual control of cardiac Na+-Ca2+ exchange by PIP2: Electrophysiological analysis of direct and indirect mechanisms

Yaradanakul, A., Feng, S., Shen, C., Lariccia, V., Lin, M. J., Yang, J., Dong, P., Yin, H. L., Albanesi, J. P. & Hilgemann, D. W., Aug 1 2007, In : Journal of Physiology. 582, 3, p. 991-1010 20 p.

Research output: Contribution to journalArticle

44 Scopus citations

Dual control of cardiac Na+-Ca2+ exchange by PIP2: Analysis of the surface membrane fraction by extracellular cysteine PEGylation

Shen, C., Lin, M. J., Yaradanakul, A., Lariccia, V., Hill, J. A. & Hilgemann, D. W., Aug 1 2007, In : Journal of Physiology. 582, 3, p. 1011-1026 16 p.

Research output: Contribution to journalArticle

20 Scopus citations

EB1 binding restricts STIM1 translocation to ER-PM junctions and regulates store-operated Ca2+ entry

Chang, C. L., Chen, Y. J., Quintanilla, C. G., Hsieh, T. S. & Liou, J., Jun 1 2018, In : Journal of Cell Biology. 217, 6, p. 2047-2058 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Expression, purification, and structural insights for the human uric acid transporter, GLUT9, using the Xenopus laevis Oocytes System

Clémençon, B., Lüscher, B. P., Fine, M., Baumann, M. U., Surbek, D. V., Bonny, O. & Hediger, M. A., Oct 6 2014, In : PloS one. 9, 10, e108852.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations
Open Access
45 Scopus citations
Open Access
38 Scopus citations

Extracellular calcium transients in frog ventricle measured with antipyrylazo III and tetramethylmurexide

Hilgemann, D. W. & Langer, G. A., Jan 1 1984, In : Federation Proceedings. 43, 4, p. No. 3130

Research output: Contribution to journalArticle

2 Scopus citations

Feedback regulation of receptor-induced ca2+ signaling mediated by e-syt1 and nir2 at endoplasmic reticulum-plasma membrane junctions

Chang, C. L., Hsieh, T. S., Yang, T. T., Rothberg, K. G., Azizoglu, D. B., Volk, E., Liao, J. C. & Liou, J., Nov 7 2013, In : Cell Reports. 5, 3, p. 813-825 13 p.

Research output: Contribution to journalArticle

155 Scopus citations

Functional comparison of the three isoforms of the Na+/Ca2+ exchanger (NCX1, NCX2, NCX3)

Linck, B., Qiu, Z., He, Z., Tong, Q., Hilgemann, D. W. & Philipson, K. D., Feb 1998, In : American Journal of Physiology - Cell Physiology. 274, 2 43-2, p. C415-C423

Research output: Contribution to journalArticle

182 Scopus citations

GAT1 (GABA:Na+:Cl-) cotransport function: Kinetic studies in giant Xenopus oocyte membrane patches

Lu, C. C. & Hilgemann, D. W., Sep 1 1999, In : Journal of General Physiology. 114, 3, p. 445-457 13 p.

Research output: Contribution to journalArticle

59 Scopus citations

GAT1 (GABA:Na+:Cl-) cotransport function: Steady state studies in giant Xenopus oocyte membrane patches

Lu, C. C. & Hilgemann, D. W., Sep 1 1999, In : Journal of General Physiology. 114, 3, p. 429-444 16 p.

Research output: Contribution to journalArticle

96 Scopus citations

GAT1 (GABA:Na+:Cl-) cotransport function: Database reconstruction with an alternating access model

Hilgemann, D. W. & Lu, C. C., Sep 1 1999, In : Journal of General Physiology. 114, 3, p. 459-475 17 p.

Research output: Contribution to journalArticle

87 Scopus citations
96 Scopus citations

Giant membrane patches: Improvements and applications

Hilgemann, D. W. & Lu, C. C., Jan 1 1998, In : Methods in Enzymology. 293, p. 267-280 14 p.

Research output: Contribution to journalArticle

52 Scopus citations

Hematopoietic Progenitor Kinase 1 Associates Physically and Functionally with the Adaptor Proteins B Cell Linker Protein and SLP-76 in Lymphocytes

Sauer, K., Liou, J., Singh, S. B., Yablonski, D., Weiss, A. & Perlmutter, R. M., Nov 30 2001, In : Journal of Biological Chemistry. 276, 48, p. 45207-45216 10 p.

Research output: Contribution to journalArticle

74 Scopus citations

Homeostatic regulation of the PI(4,5)P2-Ca2+ signaling system at ER-PM junctions

Chang, C. L. & Liou, J., Dec 10 2015, (Accepted/In press) In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids.

Research output: Contribution to journalArticle

25 Scopus citations

HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1

Liou, J., Kiefer, F., Dang, A., Hashimoto, A., Cobb, M. H., Kurosaki, T. & Weiss, A., 2000, In : Immunity. 12, 4, p. 399-408 10 p.

Research output: Contribution to journalArticle

Open Access
86 Scopus citations

Human-induced pluripotent stem cell-derived cardiomyocytes for studies of cardiac ion transporters

Fine, M., Lu, F. M., Lin, M. J., Moe, O., Wang, H. R. & Hilgemann, D. W., Sep 1 2013, In : American Journal of Physiology - Cell Physiology. 305, 5, p. C481-C491

Research output: Contribution to journalArticle

21 Scopus citations
Open Access

Identification of a peptide inhibitor of the cardiac sarcolemmal Na+-Ca2+ exchanger

Li, Z., Nicoll, D. A., Collins, A., Hilgemann, D. W., Filoteo, A. G., Penniston, J. T., Weise, J. N., Tomich, J. M. & Philipson, K. D., Feb 19 1991, In : Journal of Biological Chemistry. 266, 2, p. 1014-1020 7 p.

Research output: Contribution to journalArticle

217 Scopus citations

Inactivation of outward Na(+)‐Ca2+ exchange current in guinea‐pig ventricular myocytes.

Matsuoka, S. & Hilgemann, D. W., May 1 1994, In : The Journal of Physiology. 476, 3, p. 443-458 16 p.

Research output: Contribution to journalArticle

65 Scopus citations

Initial localization of regulatory regions of the cardiac sarcolemmal Na+-Ca2+ exchanger

Matsuoka, S., Nicoll, D. A., Reilly, R. F., Hilgemann, D. W. & Philipson, K. D., Jan 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 9, p. 3870-3874 5 p.

Research output: Contribution to journalArticle

Open Access
192 Scopus citations

Inotropic effects of activation and pharmacological mechanisms in cardiac muscle

Joachim Mensing, H. & Hilgemann, D. W., 1981, In : Trends in Pharmacological Sciences. 2, C, p. 303-307 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Interaction of PIP2 with the XIP region of the cardiac Na/Ca exchanger

He, Z., Feng, S., Tong, Q., Hilgemann, D. W. & Philipson, K. D., 2000, In : American Journal of Physiology - Cell Physiology. 278, 4 47-4, p. C661-C666

Research output: Contribution to journalArticle

76 Scopus citations

Ion fluxes in giant excised cardiac membrane patches detected and quantified with ion-selective microelectrodes

Kang, T. M., Markin, V. S. & Hilgemann, D. W., Apr 1 2003, In : Journal of General Physiology. 121, 4, p. 325-347 23 p.

Research output: Contribution to journalArticle

23 Scopus citations
66 Scopus citations

Lipid signaling to membrane proteins: From second messengers to membrane domains and adapter-free endocytosis

Hilgemann, D. W., Dai, G., Collins, A., Lariccia, V., Magi, S., Deisl, C. & Fine, M., Feb 1 2018, In : Journal of General Physiology. 150, 2, p. 211-224 14 p.

Research output: Contribution to journalArticle

18 Scopus citations
466 Scopus citations

Massive Ca-induced membrane fusion and phospholipid changes triggered by reverse Na/Ca exchange in BHK fibroblasts

Yaradanakul, A., Wang, T. M., Lariccia, V., Lin, M. J., Shen, C., Liu, X. & Hilgemann, D. W., Jul 2008, In : Journal of General Physiology. 132, 1, p. 29-50 22 p.

Research output: Contribution to journalArticle

16 Scopus citations

Massive calcium-activated endocytosis without involvement of classical endocytic proteins

Lariccia, V., Fine, M., Magi, S., Lin, M. J., Yaradanakul, A., Llaguno, M. C. & Hilgemann, D. W., Jan 2011, In : Journal of General Physiology. 137, 1, p. 111-132 22 p.

Research output: Contribution to journalArticle

67 Scopus citations

Massive endocytosis driven by lipidic forces originating in the outer plasmalemmal monolayer: A new approach to membrane recycling and lipid domains

Fine, M., Llaguno, M. C., Lariccia, V., Lin, M. J., Yaradanakul, A. & Hilgemann, D. W., Feb 2011, In : Journal of General Physiology. 137, 2, p. 137-154 18 p.

Research output: Contribution to journalArticle

28 Scopus citations

Massive endocytosis triggered by surface membrane palmitoylation under mitochondrial control in BHK fibroblasts

Hilgmann, D. W., Fine, M., Linder, M. E., Jennings, B. C. & Lin, M. J., Nov 26 2013, In : eLife. 2013, 2, e01293.

Research output: Contribution to journalArticle

38 Scopus citations