Physiology - Division E

Research Output

2006

ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice

Huang, G., Yao, J., Zeng, W., Mizuno, Y., Kamm, K. E., Stull, J. T., Harding, H. P., Ron, D. & Muallem, S., Jan 1 2006, In : Journal of cell science. 119, 1, p. 153-161 9 p.

Research output: Contribution to journalArticle

40 Scopus citations
2005

Delphinidin-3-rutinoside relaxes the bovine ciliary smooth muscle through activation of ETB receptor and NO/cGMP pathway

Matsumoto, H., Kamm, K. E., Stull, J. T. & Azuma, H., Mar 2005, In : Experimental Eye Research. 80, 3, p. 313-322 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Functional consequences of hypertrophic and dilated cardiomyopathy-causing mutations in α-tropomyosin

Chang, A. N., Harada, K., Ackerman, M. J. & Potter, J. D., Oct 7 2005, In : Journal of Biological Chemistry. 280, 40, p. 34343-34349 7 p.

Research output: Contribution to journalArticle

69 Scopus citations

Myosin light chain kinase and myosin phosphorylation effect frequency-dependent potentiation of skeletal muscle contraction

Zhi, G., Ryder, J. W., Huang, J., Ding, P., Chen, Y., Zhao, Y., Kamm, K. E. & Stull, J. T., Nov 29 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 48, p. 17519-17524 6 p.

Research output: Contribution to journalArticle

134 Scopus citations
56 Scopus citations

Sarcomeric protein mutations in dilated cardiomyopathy

Chang, A. N. & Potter, J. D., Sep 1 2005, In : Heart Failure Reviews. 10, 3, p. 225-235 11 p.

Research output: Contribution to journalReview article

101 Scopus citations
2004

Quantitative measurements of Ca2+/calmodulin binding and activation of myosin light chain kinase in cells

Geguchadze, R., Zhi, G., Lau, K. S., Isotani, E., Persechini, A., Kamm, K. E. & Stull, J. T., Jan 16 2004, In : FEBS Letters. 557, 1-3, p. 121-124 4 p.

Research output: Contribution to journalArticle

37 Scopus citations

Real-time evaluation of myosin light chain kinase activation in smooth muscle tissues from a transgenic calmodulin-biosensor mouse

Isotani, E., Zhi, G., Lau, K. S., Huang, J., Mizuno, Y., Persechini, A., Geguchadze, R., Kamm, K. E. & Stull, J. T., Apr 20 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 16, p. 6279-6284 6 p.

Research output: Contribution to journalArticle

91 Scopus citations
2003
48 Scopus citations

Skeletal muscle basement membrane-sarcolemma-cytoskeleton interaction minireview series

Campbell, K. P. & Stull, J. T., Apr 11 2003, In : Journal of Biological Chemistry. 278, 15, p. 12599-12600 2 p.

Research output: Contribution to journalShort survey

47 Scopus citations
2002

Fast-twitch skeletal muscles of dystrophic mouse pups are resistant to injury from acute mechanical stress

Grange, R. W., Gainer, T. G., Marschner, K. M., Talmadge, R. J. & Stull, J. T., Oct 2002, In : American Journal of Physiology - Cell Physiology. 283, 4 52-4, p. C1090-C1101

Research output: Contribution to journalArticle

61 Scopus citations

Navigating the signalling network in mouse cardiac myocytes

Sambrano, G. R., Frasert, I., Han, H., Ni, Y., O'Connell, T., Yan, Z. & Stull, J. T., Dec 12 2002, In : Nature. 420, 6916, p. 712-714 3 p.

Research output: Contribution to journalReview article

72 Scopus citations

Overview of the alliance for cellular signaling

Gilman, A. G., Dec 12 2002, In : Nature. 420, 6916, p. 703-706 4 p.

Research output: Contribution to journalReview article

109 Scopus citations

Phosphorylation of the regulatory light chains of myosin affects Ca2+ sensitivity of skeletal muscle contraction

Szczesna, D., Zhao, J., Jones, M., Zhi, G., Stull, J. & Potter, J. D., Jan 1 2002, In : Journal of applied physiology. 92, 4, p. 1661-1670 10 p.

Research output: Contribution to journalArticle

75 Scopus citations

Properties of long myosin light chain kinase binding to F-actin in vitro and in vivo

Smith, L., Parizi-Robinson, M., Zhu, M. S., Zhi, G., Fukui, R., Kamm, K. E. & Stull, J. T., Sep 20 2002, In : Journal of Biological Chemistry. 277, 38, p. 35597-35604 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
2001

Activation of Myosin Light Chain Kinase Requires Translocation of Bound Calmodulin

Krueger, J. K., Gallagher, S. C., Zhi, G., Geguchadze, R., Persechini, A., Stull, J. T. & Trewhella, J., Feb 16 2001, In : Journal of Biological Chemistry. 276, 7, p. 4535-4538 4 p.

Research output: Contribution to journalArticle

32 Scopus citations
57 Scopus citations

Ca2+-independent activity of nitric oxide synthase

Lee, S. J., Beckingham, K. & Stull, J. T., Jan 1 2001, In : Biochemical and Biophysical Research Communications. 284, 2, p. 526-530 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Dedicated Myosin Light Chain Kinases with Diverse Cellular Functions

Kamm, K. E. & Stull, J. T., Feb 16 2001, In : Journal of Biological Chemistry. 276, 7, p. 4527-4530 4 p.

Research output: Contribution to journalShort survey

440 Scopus citations

Familial Hypertrophic Cardiomyopathy Mutations in the Regulatory Light Chains of Myosin Affect their Structure, Ca2+ Binding, and Phosphorylation

Szczesna, D., Ghosh, D., Li, Q., Gomes, A. V., Guzman, G., Arana, C., Zhi, G., Stull, J. T. & Potter, J. D., Mar 9 2001, In : Journal of Biological Chemistry. 276, 10, p. 7086-7092 7 p.

Research output: Contribution to journalArticle

78 Scopus citations

Functional and molecular adaptations in skeletal muscle of myoglobin-mutant mice

Grange, R. W., Meeson, A., Chin, E. V. A., Lau, K. S., Stull, J. T., Shelton, J. M., Williams, R. S. & Garry, D. J., Dec 18 2001, In : American Journal of Physiology - Cell Physiology. 281, 5 50-5, p. C1487-C1494

Research output: Contribution to journalArticle

72 Scopus citations

Myosin light chain kinase- and PKC-dependent contraction of LES and esophageal smooth muscle

Sohn, U. D., Cao, W., Tang, D. C., Stull, J. T., Haeberle, J. R., Wang, C. L. A., Harnett, K. M., Behar, J. & Biancani, P., Aug 27 2001, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 281, 2 44-2, p. G467-G478

Research output: Contribution to journalArticle

30 Scopus citations

Myosin light chain kinase binding to a unique site on F-actin revealed by three-dimensional image reconstruction

Hatch, V., Zhi, G., Smith, L., Stull, J. T., Craig, R. & Lehman, W., Aug 6 2001, In : Journal of Cell Biology. 154, 3, p. 611-617 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Nitric oxide contributes to vascular smooth muscle relaxation in contracting fast-twitch muscles

Grange, R. W., Isotani, E., Lau, K. S., Kamm, K. E., Huang, P. L. & Stull, J. T., Jun 2001, In : Physiological genomics. 2001, 5, p. 35-44 10 p.

Research output: Contribution to journalArticle

71 Scopus citations

Structure and regulation of calcium/calmodulin-dependent protein kinases

Soderling, T. R. & Stull, J. T., Aug 1 2001, In : Chemical Reviews. 101, 8, p. 2341-2351 11 p.

Research output: Contribution to journalReview article

151 Scopus citations

The power stroke causes changes in the orientation and mobility of the termini of essential light chain 1 of myosin

Borejdo, J., Ushakov, D. S., Moreland, R., Akopova, I., Reshetnyak, Y., Saraswat, L. D., Kamm, K. & Lowey, S., Apr 3 2001, In : Biochemistry. 40, 13, p. 3796-3803 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Thrombin-mediated permeability of human microvascular pulmonary endothelial cells is calcium dependent

Murphy, J. T., Duffy, S. L., Hybki, D. L. & Kamm, K., Jan 1 2001, In : Journal of Trauma - Injury, Infection and Critical Care. 50, 2, p. 213-222 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
2000

Conformational requirements for Ca2+/calmodulin binding and activation of myosin light chain kinase

Padre, R. C. & Stull, J. T., Apr 21 2000, In : FEBS Letters. 472, 1, p. 148-152 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Functional assembly of fragrments from bisected smooth muscle myosin light chain kinase

Padre, R. C. & Stull, J. T., Sep 1 2000, In : Journal of Biological Chemistry. 275, 35, p. 26665-26673 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Functional muscle ischemia in neuronal nitric oxide synthase-deficient skeletal muscle of children with Duchenne muscular dystrophy

Sander, M., Chavoshan, B., Harris, S. A., Iannaccone, S. T., Stull, J. T., Thomas, G. D. & Victor, R. G., Dec 5 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 25, p. 13818-13823 6 p.

Research output: Contribution to journalArticle

314 Scopus citations

Localization and activity of myosin light chain kinase isoforms during the cell cycle

Poperechnaya, A., Varlamova, O., Lin, P. J., Stull, J. T. & Bresnick, A. R., Oct 30 2000, In : Journal of Cell Biology. 151, 3, p. 697-707 11 p.

Research output: Contribution to journalArticle

84 Scopus citations
17 Scopus citations
5 Scopus citations

Mutations at lysine 525 of inducible nitric-oxide synthase affect its Ca2+-independent activity

Lee, S. J., Beckingham, K. & Stull, J. T., Nov 17 2000, In : Journal of Biological Chemistry. 275, 46, p. 36067-36072 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Myosin light chain kinase binding to actin filaments

Smith, L. & Stull, J. T., Sep 1 2000, In : FEBS Letters. 480, 2-3, p. 298-300 3 p.

Research output: Contribution to journalArticle

28 Scopus citations

Neuronal nitric oxide synthase localizes through multiple structural motifs to the sarcolemma in mouse myotubes

Abdelmoity, A., Padre, R. C., Burzynski, K. E., Stull, J. T. & Lau, K. S., Sep 29 2000, In : FEBS Letters. 482, 1-2, p. 65-70 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle

Lau, K. S., Grange, R. W., Isotani, E., Sarelius, I. H., Kamm, K. E., Huang, P. L. & Stull, J. T., May 1 2000, In : Physiological Genomics. 2000, 2, p. 21-27 7 p.

Research output: Contribution to journalArticle

126 Scopus citations
1999

Dynamic modulation of the regulatory domain of myosin heads by pH, ionic strength, and RLC phosphorylation in synthetic myosin filaments

Adhikari, B. B., Somerset, J., Stull, J. T. & Fajer, P. G., Mar 9 1999, In : Biochemistry. 38, 10, p. 3127-3132 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Identification of a novel actin binding motif in smooth muscle myosin light chain kinase

Smith, L., Su, X., Lin, P. J., Zhi, G. & Stull, J. T., Oct 8 1999, In : Journal of Biological Chemistry. 274, 41, p. 29433-29438 6 p.

Research output: Contribution to journalArticle

52 Scopus citations

Phosphorylation-dependent structural changes in the regulatory light chain domain of smooth muscle heavy meromyosin

Wu, X., Clack, B. A., Zhi, G., Stull, J. T. & Cremo, C. R., Jul 16 1999, In : Journal of Biological Chemistry. 274, 29, p. 20328-20335 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Properties of filament-bound myosin light chain kinase

Lin, P. J., Luby-Phelps, K. & Stull, J. T., Feb 26 1999, In : Journal of Biological Chemistry. 274, 9, p. 5987-5994 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Proteins that regulate dynamic actin remodeling in response to membrane signaling minireview series

Yin, H. L. & Stull, J. T., Nov 12 1999, In : Journal of Biological Chemistry. 274, 46, p. 32529-32530 2 p.

Research output: Contribution to journalShort survey

32 Scopus citations

Role for α-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies

Grady, R. M., Grange, R. W., Lau, K. S., Maimone, M. M., Nichol, M. C., Stull, J. T. & Sanes, J. R., Aug 1999, In : Nature cell biology. 1, 4, p. 215-220 6 p.

Research output: Contribution to journalArticle

262 Scopus citations
1998

Calmodulin binding to myosin light chain kinase begins at substoichiometric Ca2+ concentrations: A small-angle scattering study of binding and conformational transitions

Krueger, J. K., Bishop, N. A., Blumenthal, D. K., Zhi, G., Beckingham, K., Stull, J. T. & Trewhella, J., Dec 22 1998, In : Biochemistry. 37, 51, p. 17810-17817 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Calmodulin-dependent regulation of inducible and neuronal nitric-oxide synthase

Lee, S. J. & Stull, J. T., Oct 16 1998, In : Journal of Biological Chemistry. 273, 42, p. 27430-27437 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Changes in interfilament spacing mimic the effects of myosin regulatory light chain phosphorylation in rabbit psoas fibers

Yang, Z., Stull, J. T., Levine, R. J. C. & Sweeney, H. L., 1998, In : Journal of Structural Biology. 122, 1-2, p. 139-148 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Differential development of umbilical and systemic arteries. II. Contractile proteins

Arens, Y., Chapados, R. A., Cox, B. E., Kamm, K. E. & Rosenfeld, C. R., Jul 14 1998, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 274, 6 43-6, p. R1815-R1823

Research output: Contribution to journalArticle

30 Scopus citations

Impaired metabolic modulation of α-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle

Thomas, G. D., Sander, M., Lau, K. S., Huang, P. L., Stull, J. T. & Victor, R. G., Dec 8 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 25, p. 15090-15095 6 p.

Research output: Contribution to journalArticle

307 Scopus citations

Mechanical loading regulates NOS expression and activity in developing and adult skeletal muscle

Tidball, J. G., Lavergne, E., Lau, K. S., Spencer, M. J., Stull, J. T. & Wehling, M., Jul 1 1998, In : American Journal of Physiology - Cell Physiology. 275, 1 44-1, p. C260-C266

Research output: Contribution to journalArticle

163 Scopus citations

Myosin light chain kinase: Functional domains and structural motifs

Stull, J. T., Lin, P. J., Krueger, J. K., Trewhella, J. & Zhi, G., Jan 1 1998, In : Acta Physiologica Scandinavica. 164, 4, p. 471-482 12 p.

Research output: Contribution to journalArticle

66 Scopus citations