Research output per year
Research output per year
- 1 - 50 out of 279 results
Search results
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2021
Resistance of Acta2R149C/+ mice to aortic disease is associated with defective release of mutant smooth muscle α-actin from the chaperonin-containing TCP1 folding complex
Chen, J., Kaw, K., Lu, H., Fagnant, P. M., Chattopadhyay, A., Duan, X. Y., Zhou, Z., Ma, S., Liu, Z., Huang, J., Kamm, K., Stull, J. T., Kwartler, C. S., Trybus, K. M. & Milewicz, D. M., Dec 1 2021, In: Journal of Biological Chemistry. 297, 6, 101228.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2020
Actin R256 Mono-methylation Is a Conserved Post-translational Modification Involved in Transcription
Kumar, A., Zhong, Y., Albrecht, A., Sang, P. B., Maples, A., Liu, Z., Vinayachandran, V., Reja, R., Lee, C. F., Kumar, A., Chen, J., Xiao, J., Park, B., Shen, J., Liu, B., Person, M. D., Trybus, K. M., Zhang, K. Y. J., Pugh, B. F., Kamm, K. E., & 3 others, Sep 29 2020, In: Cell Reports. 32, 13, 108172.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2019
The dominant protein phosphatase PP1c isoform in smooth muscle cells, PP1cβ, is essential for smooth muscle contraction
Chang, A. N., Gao, N., Liu, Z., Huang, J., Nairn, A. C., Kamm, K. E. & Stull, J. T., Oct 26 2019, In: Journal of Biological Chemistry. 293, 43, p. 16677-16686 10 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2018
Genetic approaches to identify pathological limitations in aortic smooth muscle contraction
Huang, J., Gao, N., Wang, S., Milewicz, D. M., Kamm, K. E. & Stull, J. T., Mar 2018, In: PloS one. 13, 3, e0193769.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Myosin light chain kinases
Kemp, B. E. & Stull, J. T., Jan 1 2018, Peptides and Protein Phosphorylation. CRC Press, p. 116-133 18 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Similar biophysical abnormalities in glomeruli and podocytes from two distinct models
Embry, A. E., Liu, Z., Henderson, J. M., Byfield, F. J., Liu, L., Yoon, J., Wu, Z., Cruz, K., Moradi, S., Gillombardo, C. B., Hussain, R. Z., Doelger, R., Stuve, O., Chang, A. N., Janmey, P. A., Bruggeman, L. A. & Miller, R. T., May 2018, In: Journal of the American Society of Nephrology. 29, 5, p. 1501-1512 12 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Variants of Unknown Significance in Genes Associated with Heritable Thoracic Aortic Disease Can Be Low Penetrant “Risk Variants”
Kwartler, C. S., Gong, L., Chen, J., Wang, S., Kulmacz, R., Duan, X. Y., Janda, A., Huang, J., Kamm, K. E., Stull, J. T., Guo, D. & Milewicz, D. M., Jul 5 2018, In: American Journal of Human Genetics. 103, 1, p. 138-143 6 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
2017
Altered smooth muscle cell force generation as a driver of thoracic aortic aneurysms and dissections
Milewicz, D. M., Trybus, K. M., Guo, D., Sweeney, L. L., Regalado, E., Kamm, K. & Stull, J. T., Jan 1 2017, In: Arteriosclerosis, thrombosis, and vascular biology. 37, 1, p. 26-34 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access159 Scopus citations -
Physiological vs. pharmacological signalling to myosin phosphorylation in airway smooth muscle
Gao, N., Tsai, M. H., Chang, A. N., He, W., Chen, C. P., Zhu, M., Kamm, K. E. & Stull, J. T., Oct 1 2017, In: Journal of Physiology. 595, 19, p. 6231-6247 17 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Vascular disease-causing mutation, smooth muscle α-actin R258C, dominantly suppresses functions of α-actin in human patient fibroblasts
Liu, Z., Chang, A. N., Grinnell, F., Trybus, K. M., Milewicz, D. M., Stull, J. T., Kamm, K. E. & Korn, E. D., Jul 11 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 28, p. E5569-E5578Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2016
Cardiac myosin light chain is phosphorylated by Ca2+/calmodulin-dependent and -independent kinase activities
Chang, A. N., Mahajan, P., Knapp, S., Barton, H., Sweeney, H. L., Kamm, K. E. & Stull, J. T., Jul 5 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 27, p. E3824-E3833Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
Interaction of posttetanic potentiation and the catchlike property in mouse skeletal muscle
Gittings, W., Bunda, J., Stull, J. T. & Vandenboom, R., Aug 1 2016, In: Muscle and Nerve. 54, 2, p. 308-316 9 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Physiological signalling to myosin phosphatase targeting subunit-1 phosphorylation in ileal smooth muscle
Gao, N., Chang, A. N., He, W., Chen, C. P., Qiao, Y. N., Zhu, M., Kamm, K. E. & Stull, J. T., Jun 15 2016, In: Journal of Physiology. 594, 12, p. 3209-3225 17 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Role of myosin light chain phosphatase in cardiac physiology and pathophysiology
Chang, A. N., Kamm, K. E. & Stull, J. T., Dec 1 2016, In: Journal of Molecular and Cellular Cardiology. 101, p. 35-43 9 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
2015
Constitutive phosphorylation of cardiac myosin regulatory light chain in vivo
Chang, A. N., Battiprolu, P. K., Cowley, P. M., Chen, G., Gerard, R. D., Pinto, J. R., Hill, J. A., Baker, A. J., Kamm, K. E. & Stull, J. T., Apr 24 2015, In: Journal of Biological Chemistry. 290, 17, p. 10703-10716 14 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
In vivo roles for myosin phosphatase targeting subunit-1 phosphorylation sites T694 and T852 in bladder smooth muscle contraction
Chen, C. P., Chen, X., Qiao, Y. N., Wang, P., He, W. Q., Zhang, C. H., Zhao, W., Gao, Y. Q., Chen, C., Tao, T., Sun, J., Wang, Y., Gao, N., Kamm, K. E., Stull, J. T. & Zhu, M. S., Feb 1 2015, In: Journal of Physiology. 593, 3, p. 681-700 20 p.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
The α1A-adrenergic receptor subtype mediates increased contraction of failing right ventricular myocardium
Cowley, P. M., Wang, G., Chang, A. N., Makwana, O., Swigart, P. M., Lovett, D. H., Stull, J. T., Simpson, P. C. & Baker, A. J., Sep 3 2015, In: American Journal of Physiology - Heart and Circulatory Physiology. 309, 5, p. H888-H896Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
2014
Constitutive phosphorylation of myosin phosphatase targeting subunit-1 in smooth muscle
Tsai, M. H., Chang, A. N., Huang, J., He, W., Sweeney, H. L., Zhu, M., Kamm, K. E. & Stull, J. T., Jul 15 2014, In: Journal of Physiology. 592, 14, p. 3031-3051 21 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Long term ablation of protein Kinase a (PKA)-mediated cardiac troponin I phosphorylation leads to excitation-contraction uncoupling and diastolic dysfunction in a knock-in mouse model of hypertrophic cardiomyopathy
Dweck, D., Sanchez-Gonzalez, M. A., Chang, A. N., Dulce, R. A., Badger, C. D., Koutnik, A. P., Ruiz, E. L., Griffin, B., Liang, J., Kabbaj, M., Fincham, F. D., Hare, J. M., Michael Overton, J. & Pinto, J. R., Aug 15 2014, In: Journal of Biological Chemistry. 289, 33, p. 23097-23111 15 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Myosin phosphatase target subunit 1 (MYPT1) regulates the contraction and relaxation of vascular smooth muscle and maintains blood pressure
Qiao, Y. N., He, W. Q., Chen, C. P., Zhang, C. H., Zhao, W., Wang, P., Zhang, L., Wu, Y. Z., Yang, X., Peng, Y. J., Gao, J. M., Kamm, K. E., Stull, J. T. & Zhu, M. S., Aug 8 2014, In: Journal of Biological Chemistry. 289, 32, p. 22512-22523 12 p.Research output: Contribution to journal › Article › peer-review
82 Scopus citations -
Recombinant neuregulin 1 does not activate cardiomyocyte DNA synthesis in normal or infarcted adult mice
Reuter, S., Soonpaa, M. H., Firulli, A. B., Chang, A. N. & Field, L. J., Dec 29 2014, In: PloS one. 9, 12, e115871.Research output: Contribution to journal › Article › peer-review
50 Scopus citations -
Structural and protein interaction effects of hypertrophic and dilated cardiomyopathic mutations in alpha-tropomyosin
Chang, A. N., Greenfield, N. J., Singh, A., Potter, J. D. & Pinto, J. R., 2014, In: Frontiers in Physiology. 5, DEC, 460.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
The force dependence of isometric and concentric potentiation in mouse muscle with and without skeletal myosin light chain kinase
Gittings, W., Aggarwal, H., Stull, J. T. & Vandenboom, R., Oct 14 2014, In: Canadian Journal of Physiology and Pharmacology. 93, 1, p. 23-32 10 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2013
Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing
Velasquez, L. S., Sutherland, L. B., Liu, Z., Grinnell, F., Kamm, K. E., Schneider, J. W., Olson, E. N. & Small, E. M., Oct 15 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 42, p. 16850-16855 6 p.Research output: Contribution to journal › Article › peer-review
113 Scopus citations -
Altered contractile phenotypes of intestinal smooth muscle in mice deficient in myosin phosphatase target subunit 1
He, W. Q., Qiao, Y. N., Peng, Y. J., Zha, J. M., Zhang, C. H., Chen, C., Chen, C. P., Wang, P., Yang, X., Li, C. J., Kamm, K. E., Stull, J. T. & Zhu, M. S., Jun 2013, In: Gastroenterology. 144, 7, p. 1456-1465.e5Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
Myosin phosphorylation and force potentiation in skeletal muscle: Evidence from animal models
Vandenboom, R., Gittings, W., Smith, I. C., Grange, R. W. & Stull, J. T., Dec 2013, In: Journal of Muscle Research and Cell Motility. 34, 5-6, p. 317-332 16 p.Research output: Contribution to journal › Review article › peer-review
43 Scopus citations -
Reply
He, W. Q., Stull, J. T. & Zhu, M. S., Dec 2013, In: Gastroenterology. 145, 6, p. 1495 1 p.Research output: Contribution to journal › Letter › peer-review
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Signaling through myosin light chain kinase in smooth muscles
Gao, N., Huang, J., He, W., Zhu, M., Kamm, K. E. & Stull, J. T., Mar 15 2013, In: Journal of Biological Chemistry. 288, 11, p. 7596-7605 10 p.Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
The Effects of Neuregulin on Cardiac Myosin Light Chain Kinase Gene-Ablated Hearts
Chang, A. N., Huang, J., Battiprolu, P. K., Hill, J. A., Kamm, K. E. & Stull, J. T., Jun 11 2013, In: PloS one. 8, 6, e66720.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Top-down mass spectrometry on tissue extracts and biofluids with isoelectric focusing and superficially porous silica liquid chromatography
Zhang, J., Roth, M. J., Chang, A. N., Plymire, D. A., Corbett, J. R., Greenberg, B. M. & Patrie, S. M., Nov 5 2013, In: Analytical Chemistry. 85, 21, p. 10377-10384 8 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
2012
Rare, nonsynonymous variant in the smooth muscle-specific isoform of myosin heavy chain, MYH11, R247C, alters force generation in the aorta and phenotype of smooth muscle cells
Kuang, S. Q., Kwartler, C. S., Byanova, K. L., Pham, J., Gong, L., Prakash, S. K., Huang, J., Kamm, K. E., Stull, J. T., Sweeney, H. L. & Milewicz, D. M., May 25 2012, In: Circulation research. 110, 11, p. 1411-1422 12 p.Research output: Contribution to journal › Article › peer-review
69 Scopus citations -
Signalling to contractile proteins by muscarinic and purinergic pathways in neurally stimulated bladder smooth muscle
Tsai, M. H., Kamm, K. E. & Stull, J. T., Oct 2012, In: Journal of Physiology. 590, 20, p. 5107-5121 15 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
2011
Erratum: Mutations in myosin light chain kinase cause familial aortic dissections (American Journal of Human Genetics (2010) 87 (701-707))
Wang, L., Guo, D. C., Cao, J., Gong, L., Kamm, K. E., Regalado, E., Li, L., Shete, S., He, W. Q., Zhu, M. S., Offermanns, S., Gilchrist, D., Elefteriades, J., Stull, J. T. & Milewicz, D. M., Apr 8 2011, In: American Journal of Human Genetics. 88, 4, p. 516 1 p.Research output: Contribution to journal › Comment/debate › peer-review
1 Scopus citations -
Myosin light chain kinase and the role of myosin light chain phosphorylation in skeletal muscle
Stull, J. T., Kamm, K. E. & Vandenboom, R., Jun 15 2011, In: Archives of Biochemistry and Biophysics. 510, 2, p. 120-128 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access128 Scopus citations -
Role of myosin light chain kinase in regulation of basal blood pressure and maintenance of salt-induced hypertension
He, W. Q., Qiao, Y. N., Zhang, C. H., Peng, Y. J., Chen, C., Wang, P., Gao, Y. Q., Chen, C., Chen, X., Tao, T., Su, X. H., Li, C. J., Kamm, K. E., Stull, J. T. & Zhu, M. S., Aug 2011, In: American Journal of Physiology - Heart and Circulatory Physiology. 301, 2, p. H584-H591Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations -
Sensitive and reproducible intact mass analysis of complex protein mixtures with superficially porous capillary reversed-phase liquid chromatography mass spectrometry
Roth, M. J., Plymire, D. A., Chang, A. N., Kim, J., Maresh, E. M., Larson, S. E. & Patrie, S. M., Dec 15 2011, In: Analytical Chemistry. 83, 24, p. 9586-9592 7 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
Signaling to myosin regulatory light chain in sarcomeres
Kamm, K. E. & Stull, J. T., Mar 25 2011, In: Journal of Biological Chemistry. 286, 12, p. 9941-9947 7 p.Research output: Contribution to journal › Short survey › peer-review
87 Scopus citations -
Thematic minireview series on signaling in cardiac sarcomeres in health and disease
Solaro, R. J. & Stull, J. T., Mar 25 2011, In: Journal of Biological Chemistry. 286, 12, p. 9895 1 p.Research output: Contribution to journal › Short survey › peer-review
2 Scopus citations -
2010
Cardiac myosin is a substrate for Zipper-interacting Protein Kinase (ZIPK)
Chang, A. N., Chen, G., Gerard, R. D., Kamm, K. E. & Stull, J. T., Feb 19 2010, In: Journal of Biological Chemistry. 285, 8, p. 5122-5126 5 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Cardiac myosin light chain kinase is necessary for myosin regulatory light chain phosphorylation and cardiac performance in vivo
Ding, P., Huang, J., Battiprolu, P. K., Hill, J. A., Kamm, K. E. & Stull, J. T., Dec 24 2010, In: Journal of Biological Chemistry. 285, 52, p. 40819-40829 11 p.Research output: Contribution to journal › Article › peer-review
102 Scopus citations -
Mutations in myosin light chain kinase cause familial aortic dissections
Wang, L., Guo, D. C., Cao, J., Gong, L., Kamm, K. E., Regalado, E., Li, L., Shete, S., He, W. Q., Zhu, M. S., Offermanns, S., Gilchrist, D., Elefteriades, J., Stull, J. T. & Milewicz, D. M., Nov 12 2010, In: American Journal of Human Genetics. 87, 5, p. 701-707 7 p.Research output: Contribution to journal › Article › peer-review
243 Scopus citations -
Mutations in Troponin that cause HCM, DCM AND RCM: What can we learn about thin filament function?
Willott, R. H., Gomes, A. V., Chang, A. N., Parvatiyar, M. S., Pinto, J. R. & Potter, J. D., May 1 2010, In: Journal of Molecular and Cellular Cardiology. 48, 5, p. 882-892 11 p.Research output: Contribution to journal › Review article › peer-review
168 Scopus citations -
Myosin light chain kinase is necessary for tonic airway smooth muscle contraction
Zhang, W. C., Peng, Y. J., Zhang, G. S., He, W. Q., Qiao, Y. N., Dong, Y. Y., Gao, Y. Q., Chen, C., Zhang, C. H., Li, W., Shen, H. H., Ning, W., Kamm, K. E., Stull, J. T., Gao, X. & Zhu, M. S., Feb 19 2010, In: Journal of Biological Chemistry. 285, 8, p. 5522-5531 10 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
2009
Engraftment of mesenchymal stem cells into dystrophin-deficient mice is not accompanied by functional recovery
Gang, E. J., Darabi, R., Bosnakovski, D., Xu, Z., Kamm, K. E., Kyba, M. & Perlingeiro, R. C. R., Sep 10 2009, In: Experimental Cell Research. 315, 15, p. 2624-2636 13 p.Research output: Contribution to journal › Article › peer-review
Open Access57 Scopus citations -
Signaling processes for initiating smooth muscle contraction upon neural stimulation
Ding, H. L., Ryder, J. W., Stull, J. T. & Kamm, K. E., Jun 5 2009, In: Journal of Biological Chemistry. 284, 23, p. 15541-15548 8 p.Research output: Contribution to journal › Article › peer-review
52 Scopus citations -
2008
Functional skeletal muscle regeneration from differentiating embryonic stem cells
Darabi, R., Gehlbach, K., Bachoo, R. M., Kamath, S., Osawa, M., Kamm, K. E., Kyba, M. & Perlingeiro, R. C. R., Feb 2008, In: Nature medicine. 14, 2, p. 134-143 10 p.Research output: Contribution to journal › Article › peer-review
278 Scopus citations -
Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo
Mizuno, Y., Isotani, E., Huang, J., Ding, H., Stull, J. T. & Kamm, K. E., Aug 2008, In: American Journal of Physiology - Cell Physiology. 295, 2, p. C358-C364Research output: Contribution to journal › Article › peer-review
89 Scopus citations -
Myosin Light Chain Kinase Is Central to Smooth Muscle Contraction and Required for Gastrointestinal Motility in Mice
He, W. Q., Peng, Y. J., Zhang, W. C., Lv, N., Tang, J., Chen, C., Zhang, C. H., Gao, S., Chen, H. Q., Zhi, G., Feil, R., Kamm, K. E., Stull, J. T., Gao, X. & Zhu, M. S., Aug 2008, In: Gastroenterology. 135, 2, p. 610-620.e2Research output: Contribution to journal › Article › peer-review
152 Scopus citations -
Myosin regulatory light chain phosphorylation attenuates cardiac hypertrophy
Huang, J., Shelton, J. M., Richardson, J. A., Kamm, K. E. & Stull, J. T., Jul 11 2008, In: Journal of Biological Chemistry. 283, 28, p. 19748-19756 9 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
Troponin and cardiomyopathy
Chang, A. N., Parvatiyar, M. S. & Potter, J. D., Apr 25 2008, In: Biochemical and Biophysical Research Communications. 369, 1, p. 74-81 8 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations