Physiology - Division E

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2002

Fast-twitch skeletal muscles of dystrophic mouse pups are resistant to injury from acute mechanical stress

Grange, R. W., Gainer, T. G., Marschner, K. M., Talmadge, R. J. & Stull, J. T., Oct 2002, In : American Journal of Physiology - Cell Physiology. 283, 4 52-4, p. C1090-C1101

Research output: Contribution to journalArticle

61 Scopus citations

Phosphorylation of the regulatory light chains of myosin affects Ca2+ sensitivity of skeletal muscle contraction

Szczesna, D., Zhao, J., Jones, M., Zhi, G., Stull, J. & Potter, J. D., Jan 1 2002, In : Journal of applied physiology. 92, 4, p. 1661-1670 10 p.

Research output: Contribution to journalArticle

75 Scopus citations

Properties of long myosin light chain kinase binding to F-actin in vitro and in vivo

Smith, L., Parizi-Robinson, M., Zhu, M. S., Zhi, G., Fukui, R., Kamm, K. E. & Stull, J. T., Sep 20 2002, In : Journal of Biological Chemistry. 277, 38, p. 35597-35604 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
2001

Activation of Myosin Light Chain Kinase Requires Translocation of Bound Calmodulin

Krueger, J. K., Gallagher, S. C., Zhi, G., Geguchadze, R., Persechini, A., Stull, J. T. & Trewhella, J., Feb 16 2001, In : Journal of Biological Chemistry. 276, 7, p. 4535-4538 4 p.

Research output: Contribution to journalArticle

32 Scopus citations

Ca2+-independent activity of nitric oxide synthase

Lee, S. J., Beckingham, K. & Stull, J. T., Jan 1 2001, In : Biochemical and Biophysical Research Communications. 284, 2, p. 526-530 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Familial Hypertrophic Cardiomyopathy Mutations in the Regulatory Light Chains of Myosin Affect their Structure, Ca2+ Binding, and Phosphorylation

Szczesna, D., Ghosh, D., Li, Q., Gomes, A. V., Guzman, G., Arana, C., Zhi, G., Stull, J. T. & Potter, J. D., Mar 9 2001, In : Journal of Biological Chemistry. 276, 10, p. 7086-7092 7 p.

Research output: Contribution to journalArticle

78 Scopus citations

Functional and molecular adaptations in skeletal muscle of myoglobin-mutant mice

Grange, R. W., Meeson, A., Chin, E. V. A., Lau, K. S., Stull, J. T., Shelton, J. M., Williams, R. S. & Garry, D. J., Dec 18 2001, In : American Journal of Physiology - Cell Physiology. 281, 5 50-5, p. C1487-C1494

Research output: Contribution to journalArticle

72 Scopus citations

Myosin light chain kinase- and PKC-dependent contraction of LES and esophageal smooth muscle

Sohn, U. D., Cao, W., Tang, D. C., Stull, J. T., Haeberle, J. R., Wang, C. L. A., Harnett, K. M., Behar, J. & Biancani, P., Aug 27 2001, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 281, 2 44-2, p. G467-G478

Research output: Contribution to journalArticle

30 Scopus citations

Myosin light chain kinase binding to a unique site on F-actin revealed by three-dimensional image reconstruction

Hatch, V., Zhi, G., Smith, L., Stull, J. T., Craig, R. & Lehman, W., Aug 6 2001, In : Journal of Cell Biology. 154, 3, p. 611-617 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Nitric oxide contributes to vascular smooth muscle relaxation in contracting fast-twitch muscles

Grange, R. W., Isotani, E., Lau, K. S., Kamm, K. E., Huang, P. L. & Stull, J. T., Jun 2001, In : Physiological genomics. 2001, 5, p. 35-44 10 p.

Research output: Contribution to journalArticle

71 Scopus citations

The power stroke causes changes in the orientation and mobility of the termini of essential light chain 1 of myosin

Borejdo, J., Ushakov, D. S., Moreland, R., Akopova, I., Reshetnyak, Y., Saraswat, L. D., Kamm, K. & Lowey, S., Apr 3 2001, In : Biochemistry. 40, 13, p. 3796-3803 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Thrombin-mediated permeability of human microvascular pulmonary endothelial cells is calcium dependent

Murphy, J. T., Duffy, S. L., Hybki, D. L. & Kamm, K., Jan 1 2001, In : Journal of Trauma - Injury, Infection and Critical Care. 50, 2, p. 213-222 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
2000

Conformational requirements for Ca2+/calmodulin binding and activation of myosin light chain kinase

Padre, R. C. & Stull, J. T., Apr 21 2000, In : FEBS Letters. 472, 1, p. 148-152 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Functional assembly of fragrments from bisected smooth muscle myosin light chain kinase

Padre, R. C. & Stull, J. T., Sep 1 2000, In : Journal of Biological Chemistry. 275, 35, p. 26665-26673 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Functional muscle ischemia in neuronal nitric oxide synthase-deficient skeletal muscle of children with Duchenne muscular dystrophy

Sander, M., Chavoshan, B., Harris, S. A., Iannaccone, S. T., Stull, J. T., Thomas, G. D. & Victor, R. G., Dec 5 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 25, p. 13818-13823 6 p.

Research output: Contribution to journalArticle

312 Scopus citations

Localization and activity of myosin light chain kinase isoforms during the cell cycle

Poperechnaya, A., Varlamova, O., Lin, P. J., Stull, J. T. & Bresnick, A. R., Oct 30 2000, In : Journal of Cell Biology. 151, 3, p. 697-707 11 p.

Research output: Contribution to journalArticle

84 Scopus citations
17 Scopus citations
5 Scopus citations

Mutations at lysine 525 of inducible nitric-oxide synthase affect its Ca2+-independent activity

Lee, S. J., Beckingham, K. & Stull, J. T., Nov 17 2000, In : Journal of Biological Chemistry. 275, 46, p. 36067-36072 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Myosin light chain kinase binding to actin filaments

Smith, L. & Stull, J. T., Sep 1 2000, In : FEBS Letters. 480, 2-3, p. 298-300 3 p.

Research output: Contribution to journalArticle

28 Scopus citations

Neuronal nitric oxide synthase localizes through multiple structural motifs to the sarcolemma in mouse myotubes

Abdelmoity, A., Padre, R. C., Burzynski, K. E., Stull, J. T. & Lau, K. S., Sep 29 2000, In : FEBS Letters. 482, 1-2, p. 65-70 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle

Lau, K. S., Grange, R. W., Isotani, E., Sarelius, I. H., Kamm, K. E., Huang, P. L. & Stull, J. T., May 1 2000, In : Physiological Genomics. 2000, 2, p. 21-27 7 p.

Research output: Contribution to journalArticle

126 Scopus citations
1999

Dynamic modulation of the regulatory domain of myosin heads by pH, ionic strength, and RLC phosphorylation in synthetic myosin filaments

Adhikari, B. B., Somerset, J., Stull, J. T. & Fajer, P. G., Mar 9 1999, In : Biochemistry. 38, 10, p. 3127-3132 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Identification of a novel actin binding motif in smooth muscle myosin light chain kinase

Smith, L., Su, X., Lin, P. J., Zhi, G. & Stull, J. T., Oct 8 1999, In : Journal of Biological Chemistry. 274, 41, p. 29433-29438 6 p.

Research output: Contribution to journalArticle

52 Scopus citations

Phosphorylation-dependent structural changes in the regulatory light chain domain of smooth muscle heavy meromyosin

Wu, X., Clack, B. A., Zhi, G., Stull, J. T. & Cremo, C. R., Jul 16 1999, In : Journal of Biological Chemistry. 274, 29, p. 20328-20335 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Properties of filament-bound myosin light chain kinase

Lin, P. J., Luby-Phelps, K. & Stull, J. T., Feb 26 1999, In : Journal of Biological Chemistry. 274, 9, p. 5987-5994 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Role for α-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies

Grady, R. M., Grange, R. W., Lau, K. S., Maimone, M. M., Nichol, M. C., Stull, J. T. & Sanes, J. R., Aug 1999, In : Nature cell biology. 1, 4, p. 215-220 6 p.

Research output: Contribution to journalArticle

262 Scopus citations
1998

Calmodulin binding to myosin light chain kinase begins at substoichiometric Ca2+ concentrations: A small-angle scattering study of binding and conformational transitions

Krueger, J. K., Bishop, N. A., Blumenthal, D. K., Zhi, G., Beckingham, K., Stull, J. T. & Trewhella, J., Dec 22 1998, In : Biochemistry. 37, 51, p. 17810-17817 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Calmodulin-dependent regulation of inducible and neuronal nitric-oxide synthase

Lee, S. J. & Stull, J. T., Oct 16 1998, In : Journal of Biological Chemistry. 273, 42, p. 27430-27437 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Changes in interfilament spacing mimic the effects of myosin regulatory light chain phosphorylation in rabbit psoas fibers

Yang, Z., Stull, J. T., Levine, R. J. C. & Sweeney, H. L., 1998, In : Journal of Structural Biology. 122, 1-2, p. 139-148 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Differential development of umbilical and systemic arteries. II. Contractile proteins

Arens, Y., Chapados, R. A., Cox, B. E., Kamm, K. E. & Rosenfeld, C. R., Jul 14 1998, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 274, 6 43-6, p. R1815-R1823

Research output: Contribution to journalArticle

30 Scopus citations

Impaired metabolic modulation of α-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle

Thomas, G. D., Sander, M., Lau, K. S., Huang, P. L., Stull, J. T. & Victor, R. G., Dec 8 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 25, p. 15090-15095 6 p.

Research output: Contribution to journalArticle

306 Scopus citations

Mechanical loading regulates NOS expression and activity in developing and adult skeletal muscle

Tidball, J. G., Lavergne, E., Lau, K. S., Spencer, M. J., Stull, J. T. & Wehling, M., Jul 1 1998, In : American Journal of Physiology - Cell Physiology. 275, 1 44-1, p. C260-C266

Research output: Contribution to journalArticle

163 Scopus citations

Myosin light chain kinase: Functional domains and structural motifs

Stull, J. T., Lin, P. J., Krueger, J. K., Trewhella, J. & Zhi, G., Jan 1 1998, In : Acta Physiologica Scandinavica. 164, 4, p. 471-482 12 p.

Research output: Contribution to journalArticle

66 Scopus citations

Neutron-scattering studies reveal further details of the Ca2+/calmodulin-dependent activation mechanism of myosin light chain kinase

Krueger, J. K., Zhi, G., Stull, J. T. & Trewhella, J., Oct 6 1998, In : Biochemistry. 37, 40, p. 13997-14004 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Regulatory segments of Ca2+/calmodulin-dependent protein kinases

Zhi, G., Abdullah, S. M. & Stull, J. T., Apr 10 1998, In : Journal of Biological Chemistry. 273, 15, p. 8951-8957 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Skeletal muscle contractions stimulate cGMP formation and attenuate vascular smooth muscle myosin phosphorylation via nitric oxide

Lau, K. S., Grange, R. W., Chang, W. J., Kamm, K. E., Sarelius, I. & Stull, J. T., Jul 10 1998, In : FEBS Letters. 431, 1, p. 71-74 4 p.

Research output: Contribution to journalArticle

75 Scopus citations

Sparing of mdx extraocular muscles from dystrophic pathology is not attributable to normalized concentration or distribution of neuronal nitric oxide synthase

Wehling, M., Stull, J. T., McCabe, T. J. & Tidball, J. G., Feb 1 1998, In : Neuromuscular Disorders. 8, 1, p. 22-29 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Structural and functional responses of mammalian thick filaments to alterations in myosin regulatory light chains

Levine, R. J. C., Yang, Z., Epstein, N. D., Fananapazir, L., Stull, J. T. & Sweeney, H. L., Jan 1 1998, In : Journal of Structural Biology. 122, 1-2, p. 149-161 13 p.

Research output: Contribution to journalArticle

63 Scopus citations
1997

Adenovirus-mediated transfer of the smooth muscle cell calponin gene inhibits proliferation of smooth muscle cells and fibroblasts

Jiang, Z., Grange, R. W., Walsh, M. P. & Kamm, K. E., Aug 25 1997, In : FEBS Letters. 413, 3, p. 441-445 5 p.

Research output: Contribution to journalArticle

37 Scopus citations

Binding of myosin light chain kinase to cellular actin-myosin filaments

Lin, P. J., Luby-Phelps, K. & Stull, J. T., Apr 28 1997, In : Journal of Biological Chemistry. 272, 11, p. 7412-7420 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Identification of a myofilament binding domain in conventional myosin light kinase

Su, N. & Stull, J. T., Dec 1 1997, In : FASEB Journal. 11, 9, p. A1357

Research output: Contribution to journalArticle

Localization of an actin binding domain in smooth muscle myosin light chain kinase

Gallagher, P. J. & Stull, J. T., Sep 25 1997, In : Molecular and Cellular Biochemistry. 173, 1-2, p. 51-57 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Regulatory domains of ca2+/calmodulin-dependent protein kinases

Zhi, G., Abdullah, S. & Stull, J. T., Dec 1 1997, In : FASEB Journal. 11, 9, p. A1356

Research output: Contribution to journalArticle

Stiffness of the inferior oblique neurofibrovascular bundle

Brian Stidham, D., Stager, D. R., Kamm, K. E. & Grange, R. W., Jul 15 1997, In : Investigative Ophthalmology and Visual Science. 38, 7, p. 1314-1320 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Structural basis for CA2+-independent activity of inducible nitric oxide synthase

Lee, J. & Stull, J. T., Dec 1 1997, In : FASEB Journal. 11, 9, p. A1312

Research output: Contribution to journalArticle

Structures of calmodulin and a functional myosin light chain kinase in the activated complex: A neutron scattering study

Krueger, J. K., Olah, G. A., Rokop, S. E., Zhi, G., Stull, J. T. & Trewhella, J., May 20 1997, In : Biochemistry. 36, 20, p. 6017-6023 7 p.

Research output: Contribution to journalArticle

62 Scopus citations
1996

Alterations in myometrial stress during ovine pregnancy and the puerperium

Ipson, M. A., Rosenfeld, C. R., Magness, R. R. & Kamm, K. E., Aug 1996, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 271, 2 40-2, p. R446-R454

Research output: Contribution to journalArticle

7 Scopus citations
2 Scopus citations