Research Output

2020

Active Immunotherapy to Prevent Alzheimer Disease - A DNA Amyloid β 1-42 Trimer Vaccine

Rosenberg, R. N. & Lambracht-Washington, D., Mar 2020, In : JAMA neurology. 77, 3, p. 289-290 2 p.

Research output: Contribution to journalComment/debate

A Legionella effector kinase is activated by host inositol hexakisphosphate

Sreelatha, A., Nolan, C., Park, B. C., Pawłowski, K., Tomchick, D. R. & Tagliabracci, V. S., May 1 2020, In : Journal of Biological Chemistry. 295, 18, p. 6214-6224 11 p.

Research output: Contribution to journalArticle

Open Access

Ataxic Symptoms in Huntington’s Disease Transgenic Mouse Model Are Alleviated by Chlorzoxazone

Egorova, P. A., Gavrilova, A. V. & Bezprozvanny, I. B., Apr 3 2020, In : Frontiers in Neuroscience. 14, 279.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Author Correction: FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora (Nature Communications, (2019), 10, 1, (4352), 10.1038/s41467-019-12239-w)

Liu, X., Chen, A., Caicedo-Casso, A., Cui, G., Du, M., He, Q., Lim, S., Kim, H. J., Hong, C. I. & Liu, Y., Dec 1 2020, In : Nature communications. 11, 1, 346.

Research output: Contribution to journalComment/debate

Open Access

Cadmium is associated with type 2 diabetes in a superfund site lead smelter community in Dallas, Texas

Little, B. B., Reilly, R., Walsh, B. & Vu, G. T., Jun 2020, In : International journal of environmental research and public health. 17, 12, p. 1-13 13 p., 4558.

Research output: Contribution to journalArticle

Open Access

Control of cardiac contraction by sodium: Promises, reckonings, and new beginnings

Hilgemann, D. W., Jan 2020, In : Cell Calcium. 85, 102129.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Correction to: LILRB4 ITIMs mediate the T cell suppression and infiltration of acute myeloid leukemia cells (Cellular & Molecular Immunology, (2020), 17, 3, (272-282), 10.1038/s41423-019-0321-2)

Li, Z., Deng, M., Huang, F., Jin, C., Sun, S., Chen, H., Liu, X., He, L., Sadek, A. H. & Zhang, C. C., Mar 1 2020, In : Cellular and Molecular Immunology. 17, 3, p. 302-304 3 p.

Research output: Contribution to journalComment/debate

Crystal structure of the SH3 domain of growth factor receptor-bound protein 2

Bolgov, A., Korban, S., Luzik, D., Zhemkov, V., Kim, M., Rogacheva, O. & Bezprozvanny, I., Jun 1 2020, In : Acta Crystallographica Section F:Structural Biology Communications. 76, p. 263-270 8 p.

Research output: Contribution to journalArticle

Dietary Vitamin D interacts with high phosphate-induced cardiac remodeling in rats with normal renal function

Hu, M. C., Scanni, R., Ye, J., Zhang, J., Shi, M., Maique, J., Flores, B., Moe, O. W. & Krapf, R., Mar 1 2020, In : Nephrology Dialysis Transplantation. 35, 3, p. 411-421 11 p.

Research output: Contribution to journalArticle

Essential cell-extrinsic requirement for PDIA6 in lymphoid and myeloid development

Choi, J. H., Zhong, X., Zhang, Z., Su, L., McAlpine, W., Misawa, T., Liao, T. C., Zhan, X., Russell, J., Ludwig, S., Li, X., Tang, M., Anderton, P., Moresco, E. M. Y. & Beutler, B., 2020, In : Journal of Experimental Medicine. 217, 4, e20190006.

Research output: Contribution to journalArticle

Open Access

Essential requirement for nicastrin in marginal zone and B-1 B cell development

Choi, J. H., Han, J., Theodoropoulos, P. C., Zhong, X., Wang, J., Medler, D., Ludwig, S., Zhan, X., Li, X., Tang, M., Gallagher, T., Yu, G. & Beutler, B., Mar 3 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 9, p. 4894-4901 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

The Alzheimer’s Disease Genetics Consortium, Dec 1 2020, In : Nature communications. 11, 1, 667.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

FADS3 is a Δ14Z sphingoid base desaturase that contributes to gender differences in the human plasma sphingolipidome

Karsai, G., Lone, M., Kutalik, Z., Thomas Brenna, J., Li, H., Pan, D., von Eckardstein, A. & Thorsten Hornemann, X., Jan 1 2020, In : Journal of Biological Chemistry. 295, 7, p. 1889-1897 9 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Impaired function of the suprachiasmatic nucleus rescues the loss of body temperature homeostasis caused by time-restricted feeding

Zhang, Z., Zhai, Q., Gu, Y., Zhang, T., Huang, Z., Liu, Z., Liu, Y. & Xu, Y., 2020, (Accepted/In press) In : Science Bulletin. 65, 15, p. 1268-1280 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

LILRB4 ITIMs mediate the T cell suppression and infiltration of acute myeloid leukemia cells

Li, Z., Deng, M., Huang, F., Jin, C., Sun, S., Chen, H., Liu, X., He, L., Sadek, A. H. & Zhang, C. C., Mar 1 2020, In : Cellular and Molecular Immunology. 17, 3, p. 272-282 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation

Misawa, T., SoRelle, J. A., Choi, J. H., Yue, T., Wang, K. W., McAlpine, W., Wang, J., Liu, A., Tabeta, K., Turer, E. E., Evers, B., Nair-Gill, E., Poddar, S., Su, L., Ou, F., Yu, L., Russell, J., Ludwig, S., Zhan, X., Hildebrand, S. & 5 others, Li, X., Tang, M., Murray, A. R., Moresco, E. M. Y. & Beutler, B., Jan 24 2020, In : Science Immunology. 5, 43

Research output: Contribution to journalArticle

Novel Human Polymorphisms Define a Key Role for the SLC26A6-STAS Domain in Protection From Ca2+-Oxalate Lithogenesis

Shimshilashvili, L., Aharon, S., Moe, O. W. & Ohana, E., Apr 7 2020, In : Frontiers in Pharmacology. 11, 405.

Research output: Contribution to journalArticle

Open Access
Open Access

Ontogenesis and Modulation of Intestinal Unesterified Cholesterol Sequestration in a Mouse Model of Niemann–Pick C1 Disease

Lopez, A. M., Ramirez, C. M., Taylor, A. M., Jones, R. D., Repa, J. J. & Turley, S. D., Jan 1 2020, In : Digestive Diseases and Sciences. 65, 1, p. 158-167 10 p.

Research output: Contribution to journalArticle

Parathyroid Hormone and Plasma Phosphate Are Predictors of Soluble α-Klotho Levels in Adults of European Descent

Dhayat, N. A., Pruijm, M., Ponte, B., Ackermann, D., Leichtle, A. B., Devuyst, O., Ehret, G., Guessous, I., Pechère-Bertschi, A., Pastor, J., Martin, P. Y., Burnier, M., Fiedler, G. M., Vogt, B., Moe, O. W., Bochud, M. & Fuster, D. G., Apr 1 2020, In : The Journal of clinical endocrinology and metabolism. 105, 4

Research output: Contribution to journalArticle

Presynaptic endoplasmic reticulum and neurotransmission

Bezprozvanny, I. & Kavalali, E. T., Jan 2020, In : Cell Calcium. 85, 102133.

Research output: Contribution to journalComment/debate

Open Access

Regulation of ion transport from within ion transit pathways

Hilgemann, D. W., Jan 6 2020, In : Journal of General Physiology. 152, 1, p. 1-13 13 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Signal transduction from small particles: Sulfur nanodots featuring mercury sensing, cell entry mechanism and in vitro tracking performance

Qiao, G., Liu, L., Hao, X., Zheng, J., Liu, W., Gao, J., Zhang, C. C. & Wang, Q., Feb 15 2020, In : Chemical Engineering Journal. 382, 122907.

Research output: Contribution to journalArticle

6 Scopus citations

Skeletal muscle reflex–induced sympathetic dysregulation and sensitization of muscle afferents in type 1 diabetic rats

Ishizawa, R., Kim, H. K., Hotta, N., Iwamoto, G. A., Vongpatanasin, W., Mitchell, J. H., Smith, S. A. & Mizuno, M., Jan 1 2020, (Accepted/In press) In : Hypertension. p. 1072-1081 10 p.

Research output: Contribution to journalArticle

Spatiotemporal regulation of NADP(H) phosphatase Nocturnin and its role in oxidative stress response

Laothamatas, I., Gao, P., Wickramaratne, A., Quintanilla, C. G., Dino, A., Khan, C. A., Liou, J. & Green, C. B., Jan 14 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 2, p. 993-999 7 p.

Research output: Contribution to journalArticle

Open Access

Structural insights into group II TRP channels

Fine, M., Li, X. & Dang, S., Mar 2020, In : Cell Calcium. 86, 102107.

Research output: Contribution to journalReview article

The tripartite interaction of phosphate, autophagy, and αKlotho in health maintenance

Shi, M., Maique, J., Shaffer, J., Davidson, T., Sebti, S., Fernández, Á. F., Zou, Z., Yan, S., Levine, B., Moe, O. W. & Hu, M. C., Feb 1 2020, In : FASEB Journal. 34, 2, p. 3129-3150 22 p.

Research output: Contribution to journalArticle

Open Access

TNF receptor-associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation

Semmler, S., Gagné, M., Garg, P., Pickles, S. R., Baudouin, C., Hamon-Keromen, E., Destroismaisons, L., Khalfallah, Y., Chaineau, M., Caron, E., Bayne, A. N., Trempe, J. F., Cashman, N. R., Star, A. T., Haqqani, A. S., Durcan, T. M., Meiering, E. M., Robertson, J., Grandvaux, N., Plotkin, S. S. & 3 others, McBride, H. M., Velde, C. V. & DeMartino, G. N., Mar 20 2020, In : Journal of Biological Chemistry. 295, 12, p. 3808-3825 18 p.

Research output: Contribution to journalArticle

TRP Channel: The structural era

Li, X. & Fine, M., May 2020, In : Cell Calcium. 87, 102191.

Research output: Contribution to journalEditorial

2019

2019 Herbert Tabor Young Investigator Awards: Call for nominations

DeMartino, G. N., Jan 1 2019, In : Journal of Biological Chemistry. 293, 37, 1 p.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations

2020 Herbert Tabor Early Career Investigator Awards: Call for nominations

Gierasch, L. M. & DeMartino, G. N., Sep 6 2019, In : Journal of Biological Chemistry. 294, 36, 1 p.

Research output: Contribution to journalEditorial

Open Access

A Bacterial Effector Mimics a Host HSP90 Client to Undermine Immunity

Lopez, V. A., Park, B. C., Nowak, D., Sreelatha, A., Zembek, P., Fernandez, J., Servage, K. A., Gradowski, M., Hennig, J., Tomchick, D. R., Pawłowski, K., Krzymowska, M. & Tagliabracci, V. S., Sep 19 2019, In : Cell. 179, 1, p. 205-218.e21

Research output: Contribution to journalArticle

6 Scopus citations

Acute Kidney Injury After Burn: A Cohort Study From the Parkland Burn Intensive Care Unit

Clark, A. T., Li, X., Kulangara, R., Huet, B. A., Huen, S., Madni, T. D., Imran, J. B., Phelan, H., Arnoldo, B. D., Moe, O. W., Wolf, S. E. & Neyra, J. A., Jan 1 2019, In : Journal of burn care & research : official publication of the American Burn Association. 40, 1, p. 72-78 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Aggregation-induced-emission (AIE) directed assembly of a novel responsive nanoprobe for dual targets sensing

Zhou, Z., Li, X., Zhang, Y., Zhang, C. C., Tang, Y., Gao, J., Ma, L. & Wang, Q., Jun 2019, In : Materials Science and Engineering C. 99, p. 1092-1098 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Amyloid β perturbs elevated heme flux induced with neuronal development

Vidal, C., Daescu, K., Fitzgerald, K. E., Starokadomska, A., Bezprozvanny, I. & Zhang, L., 2019, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, p. 27-37 11 p.

Research output: Contribution to journalArticle

An agonist of the MscL channel affects multiple bacterial species and increases membrane permeability and potency of common antibiotics

Wray, R., Herrera, N., Iscla, I., Wang, J. & Blount, P., Sep 1 2019, In : Molecular Microbiology. 112, 3, p. 896-905 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Analysis of Phosphatidylinositol Transfer at ER-PM Junctions in Receptor-Stimulated Live Cells

Chang, C. L. & Liou, J., Jan 1 2019, In : Methods in molecular biology (Clifton, N.J.). 1949, p. 1-11 11 p.

Research output: Contribution to journalArticle

Antagonist of neuronal store-operated calcium entry exerts beneficial effects in neurons expressing PSEN1ΔE9 mutant linked to familial Alzheimer disease

Chernyuk, D., Zernov, N., Kabirova, M., Bezprozvanny, I. & Popugaeva, E., Jul 1 2019, In : Neuroscience. 410, p. 118-127 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Antibodies raised against aldehyde-fixed antigens improve sensitivity for postembedding electron microscopy

Hussain, S., Fredriksen, I., Ringsevjen, H., Kavalali, E. T. & Davanger, S., Apr 1 2019, In : Journal of Neuroscience Methods. 317, p. 1-10 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Author Correction: TMEM16F activation by Ca 2+ triggers plasma membrane expansion and directs PD-1 trafficking (Scientific Reports, (2019), 9, 1, (619), 10.1038/s41598-018-37056-x)

Bricogne, C., Fine, M., Pereira, P. M., Sung, J., Tijani, M., Wang, Y., Henriques, R., Collins, M. K. & Hilgemann, D. W., Dec 1 2019, In : Scientific Reports. 9, 1, 7705.

Research output: Contribution to journalComment/debate

Open Access

Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (Nature Genetics, (2019), 51, 3, (414-430), 10.1038/s41588-019-0358-2)

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Sep 1 2019, In : Nature genetics. 51, 9, p. 1423-1424 2 p.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations

Biocompatible Nanoplatform Based on Mussel Adhesive Chemistry: Effective Assembly, Dual Mode Sensing, and Cellular Imaging Performance

Wu, N., Yu, A., Zhang, L., Liu, W., Gao, J., Zhang, C. & Zheng, Y., Sep 1 2019, In : Advanced Materials Interfaces. 6, 17, 1900732.

Research output: Contribution to journalArticle

10 Scopus citations

Blood-based protein predictors of dementia severity as measured by δ: Replication across biofluids and cohorts

Royall, D. R., Bishnoi, R. J., Palmer, R. F., Pavlik, V., Massman, P., Darby, E., Rodriguear, M., Ansari, A. K., DeToledo, J. C., Reddy, H., Wilms, H., Johnson, K., Perez, V., Fairchild, T., Knebl, J., O'Bryant, S. E., Hall, J. R., Johnson, L., Barber, R. C., Mains, D. & 22 others, Alvarez, L., Cullum, M., Rosenberg, R., Williams, B., Quiceno, M., Reisch, J., Hynan, L. S., Huebinger, R., Smith, J., Nguyen, T., Royall, D., Palmer, R., Polk, M., Stevens, A., Ory, M., Paydarfar, D., Bertelson, J., Woon, M., Ayres, G., Aguirre, A., Wilhelmsen, K. C. & Tilson, J. L., Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 763-774 12 p.

Research output: Contribution to journalArticle

Open Access

Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency

Jakkamsetti, V., Marin-Valencia, I., Ma, Q., Good, L. B., Terrill, T., Rajasekaran, K., Pichumani, K., Khemtong, C., Hooshyar, M. A., Sundarrajan, C., Patel, M. S., Bachoo, R. M., Malloy, C. R. & Pascual, J. M., Jan 1 2019, In : Science Translational Medicine. 11, 480, aan0457.

Research output: Contribution to journalArticle

4 Scopus citations