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2020

Control of cardiac contraction by sodium: Promises, reckonings, and new beginnings

Hilgemann, D. W., Jan 2020, In : Cell Calcium. 85, 102129.

Research output: Contribution to journalArticle

Open Access

Dietary Vitamin D interacts with high phosphate-induced cardiac remodeling in rats with normal renal function

Hu, M. C., Scanni, R., Ye, J., Zhang, J., Shi, M., Maique, J., Flores, B., Moe, O. W. & Krapf, R., Mar 1 2020, In : Nephrology Dialysis Transplantation. 35, 3, p. 411-421 11 p.

Research output: Contribution to journalArticle

Essential cell-extrinsic requirement for PDIA6 in lymphoid and myeloid development

Choi, J. H., Zhong, X., Zhang, Z., Su, L., McAlpine, W., Misawa, T., Liao, T. C., Zhan, X., Russell, J., Ludwig, S., Li, X., Tang, M., Anderton, P., Moresco, E. M. Y. & Beutler, B., Jan 1 2020, In : Journal of Experimental Medicine. 217, 4, e20190006.

Research output: Contribution to journalArticle

Open Access

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

The Alzheimer’s Disease Genetics Consortium, Dec 1 2020, In : Nature communications. 11, 1, 667.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

LILRB4 ITIMs mediate the T cell suppression and infiltration of acute myeloid leukemia cells

Li, Z., Deng, M., Huang, F., Jin, C., Sun, S., Chen, H., Liu, X., He, L., Sadek, A. H. & Zhang, C. C., Mar 1 2020, In : Cellular and Molecular Immunology. 17, 3, p. 272-282 11 p.

Research output: Contribution to journalArticle

Novel Human Polymorphisms Define a Key Role for the SLC26A6-STAS Domain in Protection From Ca2+-Oxalate Lithogenesis

Shimshilashvili, L., Aharon, S., Moe, O. W. & Ohana, E., Apr 7 2020, In : Frontiers in Pharmacology. 11, 405.

Research output: Contribution to journalArticle

Open Access

Parathyroid Hormone and Plasma Phosphate Are Predictors of Soluble α-Klotho Levels in Adults of European Descent

Dhayat, N. A., Pruijm, M., Ponte, B., Ackermann, D., Leichtle, A. B., Devuyst, O., Ehret, G., Guessous, I., Pechère-Bertschi, A., Pastor, J., Martin, P. Y., Burnier, M., Fiedler, G. M., Vogt, B., Moe, O. W., Bochud, M. & Fuster, D. G., Apr 1 2020, In : The Journal of clinical endocrinology and metabolism. 105, 4

Research output: Contribution to journalArticle

Signal transduction from small particles: Sulfur nanodots featuring mercury sensing, cell entry mechanism and in vitro tracking performance

Qiao, G., Liu, L., Hao, X., Zheng, J., Liu, W., Gao, J., Zhang, C. C. & Wang, Q., Feb 15 2020, In : Chemical Engineering Journal. 382, 122907.

Research output: Contribution to journalArticle

3 Scopus citations

Skeletal muscle reflex–induced sympathetic dysregulation and sensitization of muscle afferents in type 1 diabetic rats

Ishizawa, R., Kim, H. K., Hotta, N., Iwamoto, G. A., Vongpatanasin, W., Mitchell, J. H., Smith, S. A. & Mizuno, M., Jan 1 2020, (Accepted/In press) In : Hypertension. p. 1072-1081 10 p.

Research output: Contribution to journalArticle

Spatiotemporal regulation of NADP(H) phosphatase Nocturnin and its role in oxidative stress response

Laothamatas, I., Gao, P., Wickramaratne, A., Quintanilla, C. G., Dino, A., Khan, C. A., Liou, J. & Green, C. B., Jan 14 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 2, p. 993-999 7 p.

Research output: Contribution to journalArticle

Spectrin couples cell shape, cortical tension, and Hippo signaling in retinal epithelial morphogenesis

Deng, H., Yang, L., Wen, P., Lei, H., Blount, P. & Pan, D., Apr 6 2020, In : The Journal of cell biology. 219, 4

Research output: Contribution to journalArticle

Open Access

The tripartite interaction of phosphate, autophagy, and αKlotho in health maintenance

Shi, M., Maique, J., Shaffer, J., Davidson, T., Sebti, S., Fernández, Á. F., Zou, Z., Yan, S., Levine, B., Moe, O. W. & Hu, M. C., Feb 1 2020, In : FASEB Journal. 34, 2, p. 3129-3150 22 p.

Research output: Contribution to journalArticle

Open Access
2019

A Bacterial Effector Mimics a Host HSP90 Client to Undermine Immunity

Lopez, V. A., Park, B. C., Nowak, D., Sreelatha, A., Zembek, P., Fernandez, J., Servage, K. A., Gradowski, M., Hennig, J., Tomchick, D. R., Pawłowski, K., Krzymowska, M. & Tagliabracci, V. S., Sep 19 2019, In : Cell. 179, 1, p. 205-218.e21

Research output: Contribution to journalArticle

3 Scopus citations

Acute Kidney Injury After Burn: A Cohort Study From the Parkland Burn Intensive Care Unit

Clark, A. T., Li, X., Kulangara, R., Huet, B. A., Huen, S., Madni, T. D., Imran, J. B., Phelan, H., Arnoldo, B. D., Moe, O. W., Wolf, S. E. & Neyra, J. A., Jan 1 2019, In : Journal of burn care & research : official publication of the American Burn Association. 40, 1, p. 72-78 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Aggregation-induced-emission (AIE) directed assembly of a novel responsive nanoprobe for dual targets sensing

Zhou, Z., Li, X., Zhang, Y., Zhang, C. C., Tang, Y., Gao, J., Ma, L. & Wang, Q., Jun 2019, In : Materials Science and Engineering C. 99, p. 1092-1098 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Amyloid β perturbs elevated heme flux induced with neuronal development

Vidal, C., Daescu, K., Fitzgerald, K. E., Starokadomska, A., Bezprozvanny, I. & Zhang, L., Jan 1 2019, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, p. 27-37 11 p.

Research output: Contribution to journalArticle

An agonist of the MscL channel affects multiple bacterial species and increases membrane permeability and potency of common antibiotics

Wray, R., Herrera, N., Iscla, I., Wang, J. & Blount, P., Sep 1 2019, In : Molecular Microbiology. 112, 3, p. 896-905 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Analysis of Phosphatidylinositol Transfer at ER-PM Junctions in Receptor-Stimulated Live Cells

Chang, C. L. & Liou, J., Jan 1 2019, In : Methods in molecular biology (Clifton, N.J.). 1949, p. 1-11 11 p.

Research output: Contribution to journalArticle

Antagonist of neuronal store-operated calcium entry exerts beneficial effects in neurons expressing PSEN1ΔE9 mutant linked to familial Alzheimer disease

Chernyuk, D., Zernov, N., Kabirova, M., Bezprozvanny, I. & Popugaeva, E., Jul 1 2019, In : Neuroscience. 410, p. 118-127 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Biocompatible Nanoplatform Based on Mussel Adhesive Chemistry: Effective Assembly, Dual Mode Sensing, and Cellular Imaging Performance

Wu, N., Yu, A., Zhang, L., Liu, W., Gao, J., Zhang, C. & Zheng, Y., Sep 1 2019, In : Advanced Materials Interfaces. 6, 17, 1900732.

Research output: Contribution to journalArticle

4 Scopus citations

Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency

Jakkamsetti, V., Marin-Valencia, I., Ma, Q., Good, L. B., Terrill, T., Rajasekaran, K., Pichumani, K., Khemtong, C., Hooshyar, M. A., Sundarrajan, C., Patel, M. S., Bachoo, R., Malloy, C. R. & Pascual, J. M., Jan 1 2019, In : Science Translational Medicine. 11, 480, aan0457.

Research output: Contribution to journalArticle

2 Scopus citations

Ca2+-regulated Ca2+ channels with an RCK gating ring control plant symbiotic associations

Kim, S., Zeng, W., Bernard, S., Liao, J., Venkateshwaran, M., Ane, J. M. & Jiang, Y., Dec 1 2019, In : Nature communications. 10, 1, 3703.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Calcium hypothesis of neurodegeneration – An update

Bezprozvanny, I., Dec 17 2019, In : Biochemical and Biophysical Research Communications. 520, 4, p. 667-669 3 p.

Research output: Contribution to journalArticle

Open Access

Cas9-induced immune response: A potential caution for human genome editing

Zhang, C. C., Dec 17 2019, In : Biochemical and Biophysical Research Communications. 520, 4, p. 706-707 2 p.

Research output: Contribution to journalArticle

Open Access

Celebrating science’s next generation

Gierasch, L. M. & De Martino, G., Mar 1 2019, In : Journal of Biological Chemistry. 294, 9, p. 3323-3324 2 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Cell-specific loss of SNAP25 from cortical projection neurons allows normal development but causes subsequent neurodegeneration

Hoerder-Suabedissen, A., Korrell, K. V., Hayashi, S., Jeans, A., Ramirez, D. M. O., Grant, E., Christian, H. C., Kavalali, E. T., Wilson, M. C. & Molnár, Z., May 2019, In : Cerebral Cortex. 29, 5, p. 2148-2159 12 p., bhy127.

Research output: Contribution to journalArticle

5 Scopus citations
2 Scopus citations

CRISPR-Cas9-based mutagenesis frequently provokes on-target mRNA misregulation

Tuladhar, R., Yeu, Y., Tyler Piazza, J., Tan, Z., Rene Clemenceau, J., Wu, X., Barrett, Q., Herbert, J., Mathews, D. H., Kim, J., Hyun Hwang, T. & Lum, L., Dec 1 2019, In : Nature communications. 10, 1, 4056.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands

Li, J., Shang, G., Chen, Y. J., Brautigam, C. A., Liou, J., Zhang, X. & Bai, X. C., Sep 2019, In : eLife. 8, e47650.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Derivatives of piperazines as potential therapeutic agents for Alzheimer’s disease

Popugaeva, E., Chernyuk, D., Zhang, H., Postnikova, T. Y., Pats, K., Fedorova, E., Poroikov, V., Zaitsev, A. V. & Bezprozvanny, I., Apr 2019, In : Molecular Pharmacology. 95, 4, p. 337-348 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development

Gui, X., Deng, M., Song, H., Chen, Y., Xie, J., Li, Z., He, L., Huang, F., Xu, Y., Anami, Y., Yu, H., Yu, C., Li, L., Yuan, Z., Xu, X., Wang, Q., Chai, Y., Huang, T., Shi, Y., Tsuchikama, K. & 6 others, Charlene Liao, X., Xia, N., Gao, G. F., Zhang, N., Zhang, C. C. & An, Z., Jan 1 2019, In : Cancer Immunology Research. 7, 8, p. 1244-1257 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice

Wang, K. W., Zhan, X., McAlpine, W., Zhang, Z., Choi, J. H., Shi, H., Misawa, T., Yue, T., Zhang Ph.D., D-W., Wang, Y., Ludwig, S., Russell, J., Tang, M., Li, X., Murray, A. R., Moresco, E. M. Y., Turer, E. E. & Beutler, B., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 166, 23, p. 11380-11389 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
4 Scopus citations

Exosomes in disease: Epigenetic signals from the nervous system to the rest of the organism

Pascual, J. M. & Noble, D., Aug 24 2019, In : Neuroscience letters. 708, 1 p.

Research output: Contribution to journalArticle

FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora

Liu, X., Chen, A., Caicedo-Casso, A., Cui, G., Du, M., He, Q., Lim, S., Kim, H. J., Hong, C. I. & Liu, Y., Dec 1 2019, In : Nature communications. 10, 1, 4352.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans

Ni, M., Solmonson, A., Pan, C., Yang, C., Li, D., Notzon, A., Cai, L., Guevara, G., Zacharias, L. G., Faubert, B., Vu, H. S., Jiang, L., Ko, B., Morales, N. M., Pei, J., Vale, G., Rakheja, D., Grishin, N. V., McDonald, J. G., Gotway, G. K. & 3 others, McNutt, M. C., Pascual, J. M. & DeBerardinis, R. J., Apr 30 2019, In : Cell Reports. 27, 5, p. 1376-1386.e6

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Mar 1 2019, In : Nature genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticle

119 Scopus citations

High-Phosphate Diet Induces Exercise Intolerance and Impairs Fatty Acid Metabolism in Mice

Peri-Okonny, P., Baskin, K. K., Iwamoto, G., Mitchell, J. H., Smith, S. A., Kim, H. K., Szweda, L. I., Bassel-Duby, R., Fujikawa, T., Castorena, C. M., Richardson, J., Shelton, J. M., Ayers, C., Berry, J. D., Malladi, V. S., Hu, M. C., Moe, O. W., Scherer, P. E. & Vongpatanasin, W., Mar 12 2019, In : Circulation. 139, 11, p. 1422-1434 13 p.

Research output: Contribution to journalArticle

4 Scopus citations
1 Scopus citations
Open Access

Increased production and reduced urinary buffering of acid in uric acid stone formers is ameliorated by pioglitazone

Maalouf, N. M., Poindexter, J. R., Adams-Huet, B., Moe, O. W. & Sakhaee, K., May 2019, In : Kidney international. 95, 5, p. 1262-1268 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Insulin potentiates the response to mechanical stimuli in small dorsal root ganglion neurons and thin fibre muscle afferents in vitro

Hotta, N., Katanosaka, K., Mizumura, K., Iwamoto, G. A., Ishizawa, R., Kim, H. K., Vongpatanasin, W., Mitchell, J. H., Smith, S. A. & Mizuno, M., Oct 1 2019, In : Journal of Physiology. 597, 20, p. 5049-5062 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Interaction of the Mechanosensitive Channel, MscS, with the Membrane Bilayer through Lipid Intercalation into Grooves and Pockets

Rasmussen, T., Rasmussen, A., Yang, L., Kaul, C., Black, S., Galbiati, H., Conway, S. J., Miller, S., Blount, P. & Booth, I. R., Jan 1 2019, In : Journal of Molecular Biology.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

In vitro monitoring of glutathione via a switched-on effect based on a lanthanide incorporated carbon nanostructure with biocompatibility

Wen, Q., Zeng, Z., Liu, W., Gao, J., Zhang, H. M., Zhang, C. C. & Zheng, Y., Nov 2019, In : Synthetic Metals. 257, 116183.

Research output: Contribution to journalArticle

Open Access

Legal and ethical implications of defining an optimum means of achieving unconsciousness in assisted dying

Sinmyee, S., Pandit, V. J., Pascual, J. M., Dahan, A., Heidegger, T., Kreienbühl, G., Lubarsky, D. A. & Pandit, J. J., May 1 2019, In : Anaesthesia. 74, 5, p. 630-637 8 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution

Chakraborty, T., Driscoll, M. K., Jeffery, E., Murphy, M. M., Roudot, P., Chang, B. J., Vora, S., Wong, W. M., Nielson, C. D., Zhang, H., Zhemkov, V., Hiremath, C., De La Cruz, E. D., Yi, Y., Bezprozvanny, I., Zhao, H., Tomer, R., Heintzmann, R., Meeks, J. P., Marciano, D. K. & 4 others, Morrison, S. J., Danuser, G., Dean, K. M. & Fiolka, R., Nov 1 2019, In : Nature methods. 16, 11, p. 1109-1113 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Light stimulation parameters determine neuron dynamic characteristics

Erofeev, A., Gerasimov, E., Lavrova, A., Bolshakova, A., Postnikov, E., Bezprozvanny, I. & Vlasova, O. L., Sep 1 2019, In : Applied Sciences (Switzerland). 9, 18, 3673.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations