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2020

Bioreductively Activatable Prodrug Conjugates of Combretastatin A-1 and Combretastatin A-4 as Anticancer Agents Targeted toward Tumor-Associated Hypoxia

Winn, B. A., Devkota, L., Kuch, B., Macdonough, M. T., Strecker, T. E., Wang, Y., Shi, Z., Gerberich, J. L., Mondal, D., Ramirez, A. J., Hamel, E., Chaplin, D. J., Davis, P., Mason, R. P., Trawick, M. L. & Pinney, K. G., Apr 24 2020, In : Journal of Natural Products. 83, 4, p. 937-954 18 p.

Research output: Contribution to journalArticle

Evaluating online filtering algorithms to enhance dynamic multispectral optoacoustic tomography

O'Kelly, D., Guo, Y. & Mason, R. P., Sep 2020, In : Photoacoustics. 19, 100184.

Research output: Contribution to journalArticle

Open Access

Multiscale and morphological analysis of microvascular patterns depicted in contrast-enhanced ultrasound images

Oezdemir, I., Peng, J., Ghosh, D., Sirsi, S., Sirsi, S., Mineo, C., Shaul, P. W. & Hoyt, K., May 1 2020, In : Journal of Medical Imaging. 7, 3, 034001.

Research output: Contribution to journalArticle

2019

A Chemiluminescent Probe for HNO Quantification and Real-Time Monitoring in Living Cells

An, W., Ryan, L. S., Reeves, A. G., Bruemmer, K. J., Mouhaffel, L., Gerberich, J. L., Winters, A., Mason, R. P. & Lippert, A. R., Jan 28 2019, In : Angewandte Chemie - International Edition. 58, 5, p. 1361-1365 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression

Kalainayakan, S. P., Ghosh, P., Dey, S., Fitzgerald, K. E., Sohoni, S., Konduri, P. C., Garrossian, M., Liu, L. & Zhang, L., Dec 1 2019, In : Scientific Reports. 9, 1, 1405.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Formulation and Characterization of Chemically Cross-linked Microbubble Clusters

Hall, R. L., Juan-Sing, Z. D., Hoyt, K. & Sirsi, S. R., Aug 20 2019, In : Langmuir. 35, 33, p. 10977-10986 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Kinetics-Based Measurement of Hypoxia in Living Cells and Animals Using an Acetoxymethyl Ester Chemiluminescent Probe

Ryan, L. S., Gerberich, J., Cao, J., An, W., Jenkins, B. A., Mason, R. P. & Lippert, A. R., May 24 2019, In : ACS Sensors. 4, 5, p. 1391-1398 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Oxygen-sensitive MRI assessment of tumor response to hypoxic gas breathing challenge

Yang, D. M., Arai, T. J., Campbell, J. W., Gerberich, J. L., Zhou, H. & Mason, R. P., Jul 2019, In : NMR in biomedicine. 32, 7, e4101.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization

Niu, H., Strecker, T. E., Gerberich, J. L., Campbell, J. W., Saha, D., Mondal, D., Hamel, E., Chaplin, D. J., Mason, R. P., Trawick, M. L. & Pinney, K. G., Jun 13 2019, In : Journal of Medicinal Chemistry. 62, 11, p. 5594-5615 22 p.

Research output: Contribution to journalArticle

4 Scopus citations

The effect of flow on blood oxygen level dependent (R * 2 ) MRI of orthotopic lung tumors

Zhou, H., Belzile, O., Zhang, Z., Wagner, J., Ahn, C., Richardson, J. A., Saha, D., Brekken, R. A. & Mason, R. P., Jun 2019, In : Magnetic resonance in medicine. 81, 6, p. 3787-3797 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Energy transfer chemiluminescence for ratiometric pH imaging

An, W., Mason, R. P. & Lippert, A. R., Jan 1 2018, In : Organic and Biomolecular Chemistry. 16, 22, p. 4176-4182 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

MR-CBCT image-guided system for radiotherapy of orthotopic rat prostate tumors

Chiu, T. D., Arai, T. J., Campbell, J., Jiang, S. B., Mason, R. P. & Stojadinovic, S., May 2018, In : PloS one. 13, 5, e0198065.

Research output: Contribution to journalArticle

3 Scopus citations

Noninvasive Anatomical and Functional Imaging of Orthotopic Glioblastoma Development and Therapy using Multispectral Optoacoustic Tomography

Balasundaram, G., Ding, L., Li, X., Attia, A. B. E., Dean-Ben, X. L., Ho, C. J. H., Chandrasekharan, P., Tay, H. C., Lim, H. Q., Ong, C. B., Mason, R. P., Razansky, D. & Olivo, M., Oct 1 2018, In : Translational Oncology. 11, 5, p. 1251-1258 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Synthesis of dihydronaphthalene analogues inspired by combretastatin A-4 and their biological evaluation as anticancer agents

Maguire, C. J., Chen, Z., Mocharla, V. P., Sriram, M., Strecker, T. E., Hamel, E., Zhou, H., Lopez, R., Wang, Y., Mason, R. P., Chaplin, D. J., Trawick, M. L. & Pinney, K. G., Jan 1 2018, In : MedChemComm. 9, 10, p. 1649-1662 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Synthesis of fluorescent polythiophene dots

Liu, Z., Nahhas, A., Liu, L., Ada, E., Zhang, X. & Manohar, S. K., Jan 1 2018, In : Journal of Nanomaterials. 2018, 8987348.

Research output: Contribution to journalArticle

1 Scopus citations

Targeting phosphatidylserine with calcium-dependent protein-drug conjugates for the treatment of cancer

Li, R., Chiguru, S., Li, L., Kim, D., Velmurugan, R., Kim, D., Devanaboyina, S. C., Tian, H., Schroit, A., Mason, R. P., Ober, R. J. & Ward, E. S., Jan 1 2018, In : Molecular Cancer Therapeutics. 17, 1, p. 169-182 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

The vascular disrupting agent combretastatin A-4 phosphate causes prolonged elevation of proteins involved in heme flux and function in resistant tumor cells

Dey, S., Kumari, S., Kalainayakan, S. P., Campbell, J., Ghosh, P., Zhou, H., FitzGerald, K. E., Li, M., Mason, R. P., Zhang, L. & Liu, L., 2018, In : Oncotarget. 9, 3, p. 4090-4101 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Tomographic breathing detection: A method to noninvasively assess in situ respiratory dynamics

O'Kelly, D., Zhou, H. & Mason, R. P., May 1 2018, In : Journal of Biomedical Optics. 23, 5, 056011.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Aerosol delivery of stabilized polyester-siRNA nanoparticles to silence gene expression in orthotopic lung tumors

Yan, Y., Zhou, K., Xiong, H., Miller, J. B., Motea, E. A., Boothman, D. A., Liu, L. & Siegwart, D. J., Feb 1 2017, In : Biomaterials. 118, p. 84-93 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Interactions of Renal-Clearable Gold Nanoparticles with Tumor Microenvironments: Vasculature and Acidity Effects

Yu, M., Zhou, C., Liu, L., Zhang, S., Sun, S., Hankins, J. D., Sun, X. & Zheng, J., Apr 3 2017, In : Angewandte Chemie - International Edition. 56, 15, p. 4314-4319 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Synthesis of a cell penetrating peptide modified superparamagnetic iron oxide and MRI detection of bladder cancer

Ding, C., Wu, K., Wang, W., Guan, Z., Wang, L., Wang, X., Wang, R., Liu, L. & Fan, J., 2017, In : Oncotarget. 8, 3, p. 4718-4729 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

TRF/miR-1280 suppresses stem cell-like cells and metastasis in colorectal cancer

Huang, B., Yang, H., Cheng, X., Wang, D., Fu, S., Shen, W., Zhang, Q., Zhang, L., Xue, Z., Li, Y., Da, Y., Yang, Q., Li, Z., Liu, L., Qiao, L., Kong, Y., Yao, Z., Zhao, P., Li, M. & Zhang, R., Jun 15 2017, In : Cancer Research. 77, 12, p. 3194-3206 13 p.

Research output: Contribution to journalArticle

35 Scopus citations

Tumor physiological changes during hypofractionated stereotactic body radiation therapy assessed using multi-parametric magnetic resonance imaging

Zhou, H., Zhang, Z., Denney, R., Williams, J. S., Gerberich, J., Stojadinovic, S., Saha, D., Shelton, J. M. & Mason, R. P., 2017, In : Oncotarget. 8, 23, p. 37464-37477 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Ultrasound-stimulated drug delivery using therapeutic reconstituted high-density lipoprotein nanoparticles

Xiong, F., Nirupama, S., Sirsi, S. R., Lacko, A. & Hoyt, K., 2017, In : Nanotheranostics. 1, 4, p. 440-449 10 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2016

A role for dynamic contrast-enhanced magnetic resonance imaging in predicting tumour radiation response

Hallac, R. R., Zhou, H., Pidikiti, R., Song, K., Solberg, T., Kodibagkar, V. D., Peschke, P. & Mason, R. P., May 3 2016, (Accepted/In press) In : British Journal of Cancer.

Research output: Contribution to journalArticle

3 Scopus citations

Carbon ion radiotherapy decreases the impact of tumor heterogeneity on radiation response in experimental prostate tumors

Glowa, C., Karger, C. P., Brons, S., Zhao, D., Mason, R. P., Huber, P. E., Debus, J. & Peschke, P., Aug 10 2016, In : Cancer Letters. 378, 2, p. 97-103 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents

Devkota, L., Lin, C. M., Strecker, T. E., Wang, Y., Tidmore, J. K., Chen, Z., Guddneppanavar, R., Jelinek, C. J., Lopez, R., Liu, L., Hamel, E., Mason, R. P., Chaplin, D. J., Trawick, M. L. & Pinney, K. G., Mar 1 2016, In : Bioorganic and Medicinal Chemistry. 24, 5, p. 938-956 19 p.

Research output: Contribution to journalArticle

23 Scopus citations

Developing oxygen-enhanced magnetic resonance imaging as a prognostic biomarker of radiation response

White, D. A., Zhang, Z., Li, L., Gerberich, J., Stojadinovic, S., Peschke, P. & Mason, R. P., Sep 28 2016, In : Cancer Letters. 380, 1, p. 69-77 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Effective Rat Lung Tumor Model for Stereotactic Body Radiation Therapy

Zhang, Z., Wodzak, M., Belzile, O., Zhou, H., Sishc, B., Yan, H., Stojadinovic, S., Mason, R. P., Brekken, R. A., Chopra, R., Story, M. D., Timmerman, R. & Saha, D., Jun 1 2016, In : Radiation Research. 185, 6, p. 616-622 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells

Yan, Y., Liu, L., Xiong, H., Miller, J. B., Zhou, K., Kos, P., Huffman, K. E., Elkassih, S., Norman, J. W., Carstens, R., Kim, J., Minna, J. D. & Siegwart, D. J., Sep 27 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 39, p. E5702-E5710

Research output: Contribution to journalArticle

39 Scopus citations

Inorganic phosphate-triggered release of anti-cancer arsenic trioxide from a self-delivery system: An in vitro and in vivo study

Chen, F. Y., Yi, J. W., Gu, Z. J., Tang, B. B., Li, J. Q., Li, L., Kulkarni, P., Liu, L., Mason, R. P. & Tang, Q., Mar 21 2016, In : Nanoscale. 8, 11, p. 6094-6100 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Investigation of the strategies for targeting of the afterglow nanoparticles to tumor cells

Rashidi, L. H., Homayoni, H., Zou, X., Liu, L. & Chen, W., Mar 1 2016, In : Photodiagnosis and Photodynamic Therapy. 13, p. 244-254 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

In Vivo Chemiluminescent Imaging Agents for Nitroreductase and Tissue Oxygenation

Cao, J., Campbell, J., Liu, L., Mason, R. P. & Lippert, A. R., May 3 2016, In : Analytical Chemistry. 88, 9, p. 4995-5002 8 p.

Research output: Contribution to journalArticle

51 Scopus citations

Latex carrier for improving protoporphyrin IX for photodynamic therapy

Bui, B., Liu, L. & Chen, W., Jun 1 2016, In : Photodiagnosis and Photodynamic Therapy. 14, p. 159-165 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Synthesis and biological evaluation of benzocyclooctene-based and indene-based anticancer agents that function as inhibitors of tubulin polymerization

Herdman, C. A., Strecker, T. E., Tanpure, R. P., Chen, Z., Winters, A., Gerberich, J., Liu, L., Hamel, E., Mason, R. P., Chaplin, D. J., Trawick, M. L. & Pinney, K. G., 2016, In : MedChemComm. 7, 12, p. 2418-2427 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

The evaluation of lanthanum trapped prussian blue as a phosphate binding agent with reduced bone uptake

Chen, F. Y., Gu, Z. J., Yi, J. W., Xu, X. Z., Kulkarni, P. & Tang, Q., 2016, In : New Journal of Chemistry. 40, 3, p. 2644-2648 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Tumor radio-sensitivity assessment by means of volume data and magnetic resonance indices measured on prostate tumor bearing rats

Belfatto, A., White, D. A., Mason, R. P., Zhang, Z., Stojadinovic, S., Baroni, G. & Cerveri, P., Mar 1 2016, In : Medical physics. 43, 3, p. 1275-1284 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Wavelength shifting of chemiluminescence using quantum dots to enhance tissue light penetration

Mason, E. A., Lopez, R. & Mason, R. P., Apr 1 2016, In : Optical Materials Express. 6, 4, p. 1384-1392 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015

Acquisition, preprocessing, and reconstruction of ultralow dose volumetric CT scout for organ-based CT scan planning

Yin, Z., Yao, Y., Montillo, A., Wu, M., Edic, P. M., Kalra, M. & De Man, B., May 1 2015, In : Medical Physics. 42, 5, p. 2730-2739 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Assessment of tumor response to oxygen challenge using quantitative diffusion MRI in an animal model

Zhang, Z., Yuan, Q., Zhou, H., Zhao, D., Li, L., Gerberich, J. L. & Mason, R. P., Nov 1 2015, In : Journal of Magnetic Resonance Imaging. 42, 5, p. 1450-1457 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Chemiluminescent probes for imaging H2S in living animals

Cao, J., Lopez, R., Thacker, J. M., Moon, J. Y., Jiang, C., Morris, S. N. S., Bauer, J. H., Tao, P., Mason, R. P. & Lippert, A. R., Mar 1 2015, In : Chemical Science. 6, 3, p. 1979-1985 7 p.

Research output: Contribution to journalArticle

70 Scopus citations

Click-chemistry strategy for labeling antibodies with copper-64 via a cross-bridged tetraazamacrocyclic chelator scaffold

Kumar, A., Hao, G., Liu, L., Ramezani, S., Hsieh, J. T., Öz, O. K. & Sun, X., Apr 15 2015, In : Bioconjugate Chemistry. 26, 4, p. 782-789 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Commentary on photoacoustic tomography

Mason, R. P., Dec 1 2015, In : Journal of Nuclear Medicine. 56, 12, p. 1815-1816 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Convertible MRI contrast: Sensing the delivery and release of anti-glioma nano-drugs

Zhang, L., Zhang, Z., Mason, R. P., Sarkaria, J. N. & Zhao, D., May 12 2015, In : Scientific reports. 5, 9874.

Research output: Contribution to journalArticle

24 Scopus citations
21 Scopus citations

Dynamic oxygen challenge evaluated by NMR T1 and T2* - insights into tumor oxygenation

Zhao, D., Pacheco-Torres, J., Hallac, R. R., White, D., Peschke, P., Cerdán, S. & Mason, R. P., Aug 1 2015, In : NMR in biomedicine. 28, 8, p. 937-947 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

One-pot synthesis of functional poly(amino ester sulfide)s and utility in delivering pDNA and siRNA

Yan, Y., Xue, L., Miller, J. B., Zhou, K., Kos, P., Elkassih, S., Liu, L., Nagai, A., Xiong, H. & Siegwart, D. J., Jan 3 2015, In : Polymer (United Kingdom). 72, p. 271-280 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Structural interrogation of benzosuberene-based inhibitors of tubulin polymerization

Herdman, C. A., Devkota, L., Lin, C. M., Niu, H., Strecker, T. E., Lopez, R., Liu, L., George, C. S., Tanpure, R. P., Hamel, E., Chaplin, D. J., Mason, R. P., Trawick, M. L. & Pinney, K. G., Dec 15 2015, In : Bioorganic and Medicinal Chemistry. 23, 24, p. 7497-7520 24 p.

Research output: Contribution to journalArticle

13 Scopus citations

The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts

Strecker, T. E., Odutola, S. O., Lopez, R., Cooper, M. S., Tidmore, J. K., Charlton-Sevcik, A. K., Li, L., MacDonough, M. T., Hadimani, M. B., Ghatak, A., Liu, L., Chaplin, D. J., Mason, R. P., Pinney, K. G. & Trawick, M. L., Dec 1 2015, In : Cancer Letters. 369, 1, p. 229-241 13 p.

Research output: Contribution to journalArticle

16 Scopus citations
2014

A noninvasive tumor oxygenation imaging strategy using magnetic resonance imaging of endogenous blood and tissue water

Zhang, Z., Hallac, R. R., Peschke, P. & Mason, R. P., Feb 1 2014, In : Magnetic resonance in medicine. 71, 2, p. 561-569 9 p.

Research output: Contribution to journalArticle

19 Scopus citations