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insulin Physics & Astronomy
Insulin Receptor Medicine & Life Sciences
Insulin Medicine & Life Sciences
Chemical activation Chemical Compounds
Dual Specificity Phosphatase 1 Medicine & Life Sciences
Protein Subunits Medicine & Life Sciences
Carbamyl Phosphate Medicine & Life Sciences
Dimerization Medicine & Life Sciences

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Profiles

Research Output 2019 2019

2 Citations (Scopus)

Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex

Uchikawa, E., Choi, E., Shang, G., Yu, H. & Bai, X. C., Aug 22 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Insulin Receptor
Insulins
Chemical activation
Ligands
Dimers

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & DeBerardinis, R. J., May 16 2019, In : Nature. 569, 7756, p. E4

Research output: Contribution to journalComment/debate

Open Access
Carbamyl Phosphate
Lung Neoplasms
DNA
pyrimidine
phosphorylethanolamine
4 Citations (Scopus)

Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling

Choi, E., Kikuchi, S., Gao, H., Brodzik, K., Nassour, I., Yopp, A., Singal, A. G., Zhu, H. & Yu, H., Dec 1 2019, In : Nature communications. 10, 1, 1473.

Research output: Contribution to journalArticle

Open Access
Dual Specificity Phosphatase 1
insulin
phosphatases
regulators
Insulin Receptor