Research Output

2019

Dual-targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma

Kim, K. W., Kim, J. Y., Qiao, J., Clark, R. A., Powers, C. M., Correa, H. & Chung, D. H., Sep 1 2019, In : Oncotarget. 10, 54, p. 5645-5659 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Identification of α-N-catenin as a novel tumor suppressor in neuroblastoma

Qiao, J., Rellinger, E. J., Kim, K. W., Powers, C. M., Lee, S., Correa, H. & Chung, D. H., Jan 1 2019, In : Oncotarget. 10, 49, p. 5028-5040 13 p.

Research output: Contribution to journalArticle

Methionine triggers Ppz-mediated dephosphorylation of Art1 to promote cargo-specific endocytosis

Lee, S., Ho, H. C., Tumolo, J. M., Hsu, P. C. & MacGurn, J. A., Mar 1 2019, In : Journal of Cell Biology. 218, 3, p. 977-992 16 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2017

Elevated TIMP-1 expression is associated with a prometastatic phenotype, disease relapse, and poor survival in neuroblastoma

Paul, P., Rellinger, E. J., Qiao, J., Lee, S., Volny, N., Padmanabhan, C., Romain, C. V., Mobley, B., Correa, H. & Chung, D. H., Jan 1 2017, In : Oncotarget. 8, 47, p. 82609-82620 12 p.

Research output: Contribution to journalArticle

Open Access

Isoxazole compound ML327 blocks MYC expression and tumor formation in neuroblastoma

Rellinger, E. J., Padmanabhan, C., Qiao, J., Craig, B. T., An, H., Zhu, J., Correa, H., Waterson, A. G., Lindsley, C. W., Beauchamp, R. D. & Chung, D. H., Jan 1 2017, In : Oncotarget. 8, 53, p. 91040-91051 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

ML327 induces apoptosis and sensitizes Ewing sarcoma cells to TNF-related apoptosis-inducing ligand

Rellinger, E. J., Padmanabhan, C., Qiao, J., Appert, A., Waterson, A. G., Lindsley, C. W., Beauchamp, R. D. & Chung, D. H., Sep 16 2017, In : Biochemical and Biophysical Research Communications. 491, 2, p. 463-468 6 p.

Research output: Contribution to journalArticle

2016

Activation of GRP/GRP-R signaling contributes to castrationresistant prostate cancer progression

Qiao, J., Grabowska, M. M., Forestier-Roman, I. S., Mirosevich, J., Case, T. C., Chung, D. H., Cates, J. M. M., Matusik, R. J., Manning, H. C. & Jin, R., Jan 1 2016, In : Oncotarget. 7, 38, p. 61955-61969 15 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2015

Expression of MYCN in multipotent sympathoadrenal progenitors induces proliferation and neural differentiation, but is not sufficient for tumorigenesis

Mobley, B. C., Kwon, M., Kraemer, B. R., Hickman, F. E., Qiao, J., Chung, D. H. & Carter, B. D., Jul 29 2015, In : PloS one. 10, 7, e0133897.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Silencing gastrin-releasing peptide receptor suppresses key regulators of aerobic glycolysis in neuroblastoma cells

Rellinger, E. J., Romain, C., Choi, S., Qiao, J. & Chung, D. H., Apr 1 2015, In : Pediatric Blood and Cancer. 62, 4, p. 581-586 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

Silencing of CDC42 inhibits neuroblastoma cell proliferation and transformation

Lee, S., Craig, B. T., Romain, C. V., Qiao, J. & Chung, D. H., Dec 28 2014, In : Cancer Letters. 355, 2, p. 210-216 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Targeting Aurora kinase-A downregulates cell proliferation and angiogenesis in neuroblastoma

Romain, C., Paul, P., Kim, K. W., Lee, S., Qiao, J. & Chung, D. H., Jan 1 2014, In : Journal of Pediatric Surgery. 49, 1, p. 159-165 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Targeting aurora kinase a inhibits hypoxia-mediated neuroblastoma cell tumorigenesis

Romain, C. V., Paul, P., Lee, S., Qiao, J. & Chung, D. H., May 1 2014, In : Anticancer Research. 34, 5, p. 2269-2274 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
2013

Akt2 Regulates Metastatic Potential in Neuroblastoma

Qiao, J., Lee, S., Paul, P., Qiao, L., Taylor, C. J., Schlegel, C., Colon, N. C. & Chung, D. H., Feb 26 2013, In : PloS one. 8, 2, e56382.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Autophagy mediates paracrine regulation of vascular endothelial cells

Woon Kim, K., Paul, P., Qiao, J. & Chung, D. H., Jun 1 2013, In : Laboratory Investigation. 93, 6, p. 639-645 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Differential regulation of cyclin-dependent kinase inhibitors in neuroblastoma cells

Qiao, L., Paul, P., Lee, S., Qiao, J., Wang, Y. & Chung, D. H., May 31 2013, In : Biochemical and Biophysical Research Communications. 435, 2, p. 295-299 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Enhanced autophagy blocks angiogenesis via degradation of gastrin-releasing peptide in neuroblastoma cells

Kim, K. W., Paul, P., Qiao, J., Lee, S. & Chung, D. H., Oct 2013, In : Autophagy. 9, 10, p. 1579-1590 12 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations

Gli1 transcriptional activity is negatively regulated by AKT2 in neuroblastoma

Paul, P., Volny, N., Lee, S., Qiao, J. & Chung, D. H., 2013, In : Oncotarget. 4, 8, p. 1149-1157 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Integrin β1 is critical for gastrin-releasing peptide receptor-mediated neuroblastoma cell migration and invasion

Lee, S., Qiao, J., Paul, P. & Chung, D. H., Aug 1 2013, In : Surgery (United States). 154, 2, p. 369-375 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Magneto-fluorescent carbon nanotube-mediated siRNA for gastrin-releasing peptide receptor silencing in neuroblastoma

Qiao, J., Hong, T., Triana, T. S., Guo, H., Chung, D. H. & Xu, Y. Q., Apr 14 2013, In : RSC Advances. 3, 14, p. 4544-4551 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

MiR-335 and miR-363 regulation of neuroblastoma tumorigenesis and metastasis

Qiao, J., Lee, S., Paul, P., Theiss, L., Tiao, J., Qiao, L., Kong, A. & Chung, D. H., Aug 1 2013, In : Surgery (United States). 154, 2, p. 226-233 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Single-walled carbon nanotube-mediated small interfering RNA delivery for Gastrin-releasing peptide receptor silencing in human neuroblastoma

Qiao, J., Hong, T., Guo, H., Xu, Y. Q. & Chung, D. H., Sep 3 2013, NanoBiotechnology Protocols. p. 137-147 11 p. (Methods in Molecular Biology; vol. 1026).

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Scopus citations

Targeting Gastrin-Releasing Peptide Suppresses Neuroblastoma Progression via Upregulation of PTEN Signaling

Paul, P., Qiao, J., Kim, K. W., Romain, C., Lee, S., Volny, N., Mobley, B., Correa, H. & Chung, D. H., Sep 9 2013, In : PloS one. 8, 9, e72570.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2012

Fak is a critical regulator of neuroblastoma liver metastasis

Lee, S., Qiao, J., Paul, P., O'connor, K. L., Evers, M. B. & Chung, D. H., Dec 2012, In : Oncotarget. 3, 12, p. 1576-1587 12 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

PI3K/AKT and ERK regulate retinoic acid-induced neuroblastoma cellular differentiation

Qiao, J., Paul, P., Lee, S., Qiao, L., Josifi, E., Tiao, J. R. & Chung, D. H., Aug 3 2012, In : Biochemical and Biophysical Research Communications. 424, 3, p. 421-426 6 p.

Research output: Contribution to journalArticle

58 Scopus citations

Protein kinase C regulates bombesin-induced rapid VEGF secretion in neuroblastoma cells

Schlegel, C., Paul, P., Lee, S., Kim, K. W., Colon, N., Qiao, J. & Chung, D. H., Nov 1 2012, In : Anticancer Research. 32, 11, p. 4691-4696 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
2011

Integrin-linked kinase regulates phosphatase and tensin homologue activity to promote tumorigenesis in neuroblastoma cells

Taylor, C. J., Qiao, J., Colon, N. C., Schlegel, C., Josifi, E. & Chung, D. H., Aug 1 2011, In : Surgery. 150, 2, p. 162-168 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Targeting gastrin-releasing peptide as a new approach to treat aggressive refractory neuroblastomas

Paul, P., Gillory, L. A., Kang, J., Qiao, J. & Chung, D. H., Mar 1 2011, In : Surgery. 149, 3, p. 425-432 8 p.

Research output: Contribution to journalArticle

5 Scopus citations
2009

PKD prevents H2O2-induced apoptosis via NF-κB and p38 MAPK in RIE-1 cells

Song, J., Li, J., Qiao, J., Jain, S., Mark Evers, B. & Chung, D. H., Jan 16 2009, In : Biochemical and Biophysical Research Communications. 378, 3, p. 610-614 5 p.

Research output: Contribution to journalArticle

36 Scopus citations
2008

Gastrin-releasing peptide receptor silencing suppresses the tumorigenesis and metastatic potential of neuroblastoma

Qiao, J., Kang, J., Ishola, T. A., Rychahou, P. G., Evers, B. M. & Chung, D. H., Sep 2 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 35, p. 12891-12896 6 p.

Research output: Contribution to journalArticle

52 Scopus citations
2007

Ets1 transcription factor mediates gastrin-releasing peptide-induced IL-8 regulation in neuroblastoma cells

Qiao, J., Kang, J. H., Cree, J., Evers, B. M. & Chung, D. H., Mar 2007, In : Neoplasia. 9, 3, p. 184-191 8 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Phosphatidylinositol 3-kinase regulation of gastrin-releasing peptide-induced cell cycle progression in neuroblastoma cells

Ishola, T. A., Kang, J. H., Qiao, J., Evers, B. M. & Chung, D. H., Jun 1 2007, In : Biochimica et Biophysica Acta - General Subjects. 1770, 6, p. 927-932 6 p.

Research output: Contribution to journalArticle

34 Scopus citations
2006

Inhibition of transforming growth factor-β/Smad signaling by phosphatidylinositol 3-kinase pathway

Qiao, J., Kang, J., Ko, T. C., Evers, B. M. & Chung, D. H., Oct 28 2006, In : Cancer Letters. 242, 2, p. 207-214 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

MYCN silencing induces differentiation and apoptosis in human neuroblastoma cells

Kang, J. H., Rychahou, P. G., Ishola, T. A., Qiao, J., Evers, B. M. & Chung, D. H., Dec 8 2006, In : Biochemical and Biophysical Research Communications. 351, 1, p. 192-197 6 p.

Research output: Contribution to journalArticle

79 Scopus citations
2005

Gastrin-releasing peptide-induced down-regulation of tumor suppressor protein PTEN (phosphatase and tensin homolog deleted on chromosome ten) in neuroblastomas

Qiao, J., Kang, J., Cree, J., Evers, B. M., Chung, D. H., Lally, K. P., Langham, M. R. & Tepas, J. J., May 1 2005, In : Annals of surgery. 241, 5, p. 684-692 9 p.

Research output: Contribution to journalArticle

31 Scopus citations
2004

Ets transcriptional regulation of gastrin-releasing peptide receptor in neuroblastomas

Qiao, J., Cree, J., Kang, J., Kim, S., Evers, B. M. & Chung, D. H., Aug 1 2004, In : Surgery. 136, 2, p. 489-494 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Phosphatidylinositol 3-Kinase Inhibition Down-Regulates Survivin and Facilitates TRAIL-Mediated Apoptosis in Neuroblastomas

Kim, S., Kang, J., Qiao, J., Thomas, R. P., Evers, B. M. & Chung, D. H., Apr 2004, In : Journal of Pediatric Surgery. 39, 4, p. 516-521 6 p.

Research output: Contribution to journalArticle

64 Scopus citations
2003

Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis

Chiang, C. W., Kanies, C., Kim, K. W., Fang, W. B., Parkhurst, C., Xie, M., Henry, T. & Yang, E., Sep 1 2003, In : Molecular and cellular biology. 23, 18, p. 6350-6362 13 p.

Research output: Contribution to journalArticle

Open Access
125 Scopus citations
2002

Cell cycle-dependent subcellular localization of exchange factor directly activated by cAMP

Qiao, J., Mei, F. C., Popov, V. L., Vergara, L. A. & Cheng, X., Jul 19 2002, In : Journal of Biological Chemistry. 277, 29, p. 26581-26586 6 p.

Research output: Contribution to journalArticle

Open Access
131 Scopus citations

Differential signaling of cyclic AMP. Opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation

Mei, F. C., Qiao, J., Tsygankova, O. M., Meinkoth, J. L., Quilliam, L. A. & Cheng, X., Mar 29 2002, In : Journal of Biological Chemistry. 277, 13, p. 11497-11504 8 p.

Research output: Contribution to journalArticle

Open Access
226 Scopus citations

Enhanced resistance to salt, cold and wound stresses by overproduction of animal cell death suppressors Bcl-xL and Ced-9 in tobacco cells - Their possible contribution through improved function of organella

Qiao, J., Mitsuhara, I., Yazaki, Y., Sakano, K., Gotoh, Y., Miura, M. & Ohashi, Y., Sep 1 2002, In : Plant and Cell Physiology. 43, 9, p. 992-1005 14 p.

Research output: Contribution to journalArticle

Open Access
44 Scopus citations