SY-Lab Tang Kang

Research output

Research output per year 2018 2020 2021 2022 2023 2024

• 97 Article
• 66 Review article
• 10 Chapter
• 10 Comment/debate
• 11 More
  • 8 Editorial
  • 1 Book
  • 1 Letter
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2024

  Ferroptosis in immunostimulation and immunosuppression

  Tang, D., Kroemer, G. & Kang, R., Jan 2024, In: Immunological Reviews. 321, 1, p. 199-210 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Ferroptosis 100%
  • Immunosuppression 57%
  • Immunization 53%
  • Regulated Cell Death 19%
  • Immune Tolerance 15%
  8 Scopus citations

• HMGB1 in the interplay between autophagy and apoptosis in cancer

  Chen, R., Zou, J., Zhong, X., Li, J., Kang, R. & Tang, D., Jan 28 2024, In: Cancer Letters. 581, 216494.

  Research output: Contribution to journal › Article › peer-review

  • Autophagy 100%
  • Apoptosis 63%
  • Non Histone Chromosomal Proteins 43%
  • Neoplasms 33%
  • Lysosomes 26%

• Targeting paraptosis in cancer: opportunities and challenges

  Chen, F., Tang, H., Cai, X., Lin, J., Xiang, L., Kang, R., Liu, J. & Tang, D., Mar 2024, In: Cancer Gene Therapy. 31, 3, p. 349-363 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Regulated Cell Death 100%
  • Cell Death 65%
  • Neoplasms 27%
  • DNA Fragmentation 22%
  • Heat-Shock Proteins 22%

• The lipid basis of cell death and autophagy

  Lin, Z., Long, F., Kang, R., Klionsky, D. J., Yang, M. & Tang, D., 2024, In: Autophagy. 20, 3, p. 469-488 20 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Regulated Cell Death 100%
  • Autophagy 61%
  • Cell Death 48%
  • Lipids 42%
  • Unsaturated Fatty Acids 27%
  7 Scopus citations
• 2023

  ACSS2-mediated NF-κB activation promotes alkaliptosis in human pancreatic cancer cells

  Que, D., Kuang, F., Kang, R., Tang, D. & Liu, J., Dec 2023, In: Scientific reports. 13, 1, 1483.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Acetyl Coenzyme A 100%
  • Pancreatic Neoplasms 71%
  • N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl)benzamide 62%
  • Adenocarcinoma 47%
  • Cell Death 23%
  8 Scopus citations

• Activating an Adaptive Immune Response with a Telomerase-Mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma

  Mender, I., Siteni, S., Barron, S., Flusche, A. M., Kubota, N., Yu, C., Cornelius, C., Tedone, E., Maziveyi, M., Grichuk, A., Venkateswaran, N., Conacci-Sorrell, M., Hoshida, Y., Kang, R., Tang, D., Gryaznov, S. & Shay, J. W., Jun 1 2023, In: Molecular Cancer Therapeutics. 22, 6, p. 737-750 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Telomerase 100%
  • Telomere 96%
  • Adaptive Immunity 89%
  • Hepatocellular Carcinoma 70%
  • HMGB1 Protein 23%
  2 Scopus citations

• Apoptotic cell death in disease—Current understanding of the NCCD 2023

  Vitale, I., Pietrocola, F., Guilbaud, E., Aaronson, S. A., Abrams, J. M., Adam, D., Agostini, M., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Aqeilan, R. I., Arama, E., Baehrecke, E. H., Balachandran, S., Bano, D., Barlev, N. A., Bartek, J., Bazan, N. G., & 208 othersBecker, C., Bernassola, F., Bertrand, M. J. M., Bianchi, M. E., Blagosklonny, M. V., Blander, J. M., Blandino, G., Blomgren, K., Borner, C., Bortner, C. D., Bove, P., Boya, P., Brenner, C., Broz, P., Brunner, T., Damgaard, R. B., Calin, G. A., Campanella, M., Candi, E., Carbone, M., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chen, G. Q., Chen, Q., Chen, Y. H., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Ciliberto, G., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D’Angiolella, V., Daugaard, M., Dawson, T. M., Dawson, V. L., De Maria, R., De Strooper, B., Debatin, K. M., Deberardinis, R. J., Degterev, A., Del Sal, G., Deshmukh, M., Di Virgilio, F., Diederich, M., Dixon, S. J., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Engeland, K., Fimia, G. M., Galassi, C., Ganini, C., Garcia-Saez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Gerlic, M., Ghosh, S., Green, D. R., Greene, L. A., Gronemeyer, H., Häcker, G., Hajnóczky, G., Hardwick, J. M., Haupt, Y., He, S., Heery, D. M., Hengartner, M. O., Hetz, C., Hildeman, D. A., Ichijo, H., Inoue, S., Jäättelä, M., Janic, A., Joseph, B., Jost, P. J., Kanneganti, T. D., Karin, M., Kashkar, H., Kaufmann, T., Kelly, G. L., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Kluck, R., Krysko, D. V., Kulms, D., Kumar, S., Lavandero, S., Lavrik, I. N., Lemasters, J. J., Liccardi, G., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Luedde, T., MacFarlane, M., Madeo, F., Malorni, W., Manic, G., Mantovani, R., Marchi, S., Marine, J. C., Martin, S. J., Martinou, J. C., Mastroberardino, P. G., Medema, J. P., Mehlen, P., Meier, P., Melino, G., Melino, S., Miao, E. A., Moll, U. M., Muñoz-Pinedo, C., Murphy, D. J., Niklison-Chirou, M. V., Novelli, F., Núñez, G., Oberst, A., Ofengeim, D., Opferman, J. T., Oren, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pentimalli, F., Pereira, D. M., Pervaiz, S., Peter, M. E., Pinton, P., Porta, G., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rajalingam, K., Ravichandran, K. S., Rehm, M., Ricci, J. E., Rizzuto, R., Robinson, N., Rodrigues, C. M. P., Rotblat, B., Rothlin, C. V., Rubinsztein, D. C., Rudel, T., Rufini, A., Ryan, K. M., Sarosiek, K. A., Sawa, A., Sayan, E., Schroder, K., Scorrano, L., Sesti, F., Shao, F., Shi, Y., Sica, G. S., Silke, J., Simon, H. U., Sistigu, A., Stephanou, A., Stockwell, B. R., Strapazzon, F., Strasser, A., Sun, L., Sun, E., Sun, Q., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Troy, C. M., Turk, B., Urbano, N., Vandenabeele, P., Vanden Berghe, T., Vander Heiden, M. G., Vanderluit, J. L., Verkhratsky, A., Villunger, A., von Karstedt, S., Voss, A. K., Vousden, K. H., Vucic, D., Vuri, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, R., Wang, Y., Weber, A., Wood, W., Yamazaki, T., Yang, H. T., Zakeri, Z., Zawacka-Pankau, J. E., Zhang, L., Zhang, H., Zhivotovsky, B., Zhou, W., Piacentini, M., Kroemer, G. & Galluzzi, L., May 2023, In: Cell Death and Differentiation. 30, 5, p. 1097-1154 58 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Terminology 100%
  • Cell Death 75%
  • Apoptosis 60%
  • Regulated Cell Death 51%
  • Homeostasis 48%
  66 Scopus citations

• ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis

  Chen, F., Zhu, S., Kang, R., Tang, D. & Liu, J., Jan 31 2023, In: Cell Reports. 42, 1, 111911.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Opioid Analgesic 100%
  • N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl)benzamide 84%
  • Drug Target 62%
  • Cell Death 58%
  • Mutation 46%
  13 Scopus citations

• Autophagy-dependent ferroptosis as a potential treatment for glioblastoma

  Xie, Y., Hou, T., Liu, J., Zhang, H., Liu, X., Kang, R. & Tang, D., Feb 10 2023, In: Frontiers in Oncology. 13, 1091118.

  Research output: Contribution to journal › Short survey › peer-review

  Open Access

  • Ferroptosis 100%
  • Glioblastoma 62%
  • Autophagy 60%
  • Cell Death 12%
  • Therapeutics 10%
  6 Scopus citations

• Autophagy-Dependent Ferroptosis in Cancer

  Chen, F., Cai, X., Kang, R., Liu, J. & Tang, D., Jul 1 2023, In: Antioxidants and Redox Signaling. 39, 1-3, p. 79-101 23 p.

  Research output: Contribution to journal › Review article › peer-review

  • Ferroptosis 100%
  • Cell Death 67%
  • Autophagy 60%
  • Lipid 32%
  • Neoplasms 20%
  27 Scopus citations

• Bilirubin inhibits lung carcinogenesis by up-regulating cystatin A expression in tumor-infiltrating macrophages

  Huang, Q., Zhang, N., Wang, J., Xu, H., Yao, L., Yang, Q., Yan, D., Chen, X., Xue, Q., Xiao, M., Wu, J., Wu, X., Liu, Q., Tang, D., Chen, X., Li, X. & Liu, J., Nov 2023, In: Genes and Diseases. 10, 6, p. 2222-2225 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Cell type-specific induction of ferroptosis to boost antitumor immunity

  Liu, J., Li, J., Kang, R. & Tang, D., 2023, In: OncoImmunology. 12, 1, 2282252.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  • Ferroptosis 100%
  • Immunity 51%
  • Neoplasms 6%
  3 Scopus citations

• Cholesterol Metabolism in Cancer and Cell Death

  Chen, F., Lu, Y., Lin, J., Kang, R. & Liu, J., Jul 1 2023, In: Antioxidants and Redox Signaling. 39, 1-3, p. 102-140 39 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cell Death 100%
  • Cholesterol 83%
  • Pharmacological Metabolism 72%
  • Neoplasms 30%
  • Entosis 20%
  3 Scopus citations

• Copper-dependent autophagic degradation of GPX4 drives ferroptosis

  Xue, Q., Yan, D., Chen, X., Li, X., Kang, R., Klionsky, D. J., Kroemer, G., Chen, X., Tang, D. & Liu, J., 2023, In: Autophagy. 19, 7, p. 1982-1996 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phospholipid Hydroperoxide Glutathione Peroxidase 100%
  • Ferroptosis 97%
  • Drive 63%
  • Copper 61%
  • Carrier Proteins 15%
  79 Scopus citations

• Copper metabolism in cell death and autophagy

  Xue, Q., Kang, R., Klionsky, D. J., Tang, D., Liu, J. & Chen, X., 2023, In: Autophagy. 19, 8, p. 2175-2195 21 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Copper 100%
  • Autophagy 96%
  • Cell Death 75%
  • Electron Transport Complex IV 58%
  • Autophagy-Related Protein-1 Homolog 34%
  58 Scopus citations

• Correction: The KRAS-G12C inhibitor: activity and resistance (Cancer Gene Therapy, (2022), 29, 7, (875-878), 10.1038/s41417-021-00383-9)

  Liu, J., Kang, R. & Tang, D., Dec 2023, In: Cancer Gene Therapy. 30, 12, p. 1715 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Guanine 100%
  • Neoplasm Genes 91%
  • Genetic Therapy 78%
  • Mutation 47%
  • Guanosine Triphosphate 44%

• EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer

  Wang, Y., Liu, Y., Wang, C., Kang, R., Tang, D. & Liu, J., Dec 2023, In: Scientific reports. 13, 1, 15004.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ferroptosis 100%
  • Acetylation 66%
  • Pancreatic Neoplasms 59%
  • Adenocarcinoma 21%
  • Histone Deacetylase 6 14%
  1 Scopus citations

• Extracellular SQSTM1 exacerbates acute pancreatitis by activating autophagy-dependent ferroptosis

  Yang, L., Ye, F., Liu, J., Klionsky, D. J., Tang, D. & Kang, R., 2023, In: Autophagy. 19, 6, p. 1733-1744 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ferroptosis 100%
  • Pancreatitis 61%
  • Autophagy 60%
  • Receptor for Advanced Glycation End Products 27%
  • 5-hydroxy-6,8,11,14-eicosatetraenoic acid 22%
  13 Scopus citations

• Ferroptosis in gastrointestinal cancer: from mechanisms to implications

  Zhang, R., Kang, R. & Tang, D., May 1 2023, In: Cancer Letters. 561, 216147.

  Research output: Contribution to journal › Review article › peer-review

  • Ferroptosis 100%
  • Gastrointestinal Neoplasms 75%
  • Regulated Cell Death 49%
  • Anal Canal 17%
  • Biliary Tract 17%
  13 Scopus citations

• Ferroptosis in hepatocellular carcinoma: mechanisms and targeted therapy

  Ajoolabady, A., Tang, D., Kroemer, G. & Ren, J., Jan 19 2023, In: British journal of cancer. 128, 2, p. 190-205 16 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Ferroptosis 100%
  • Hepatocellular Carcinoma 50%
  • Cell Death 38%
  • Behavioral Genetics 17%
  • Iron Overload 15%
  22 Scopus citations

• Fluorogenic Probes for Intracellular Iron Detection

  Wu, R., Tang, D. & Kang, R., 2023, Methods in Molecular Biology. Humana Press Inc., p. 1-8 8 p. (Methods in Molecular Biology; vol. 2712).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Iron 100%
  • Ferroptosis 37%
  • calcein AM 18%
  • Iron Overload 14%
  • Electron Transport 13%

• From Oxytosis to Ferroptosis: 10 Years of Research on Oxidative Cell Death

  Tang, D. & Kang, R., Jul 1 2023, In: Antioxidants and Redox Signaling. 39, 1-3, p. 162-165 4 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Ferroptosis 100%
  • Cell Death 67%
  • Cystine 23%
  • Glutathione 22%
  • erastin 16%
  3 Scopus citations

• Glimmers of hope for targeting oncogenic KRAS-G12D

  Tang, D. & Kang, R., Mar 2023, In: Cancer Gene Therapy. 30, 3, p. 391-393 3 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

  • Lung Neoplasms 100%
  • Drug Design 72%
  • Mutant Proteins 67%
  • Point Mutation 61%
  • Pancreatic Neoplasms 59%
  9 Scopus citations

• GPX4 in cell death, autophagy, and disease

  Xie, Y., Kang, R., Klionsky, D. J. & Tang, D., 2023, In: Autophagy. 19, 10, p. 2621-2638 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Phospholipid Hydroperoxide Glutathione Peroxidase 100%
  • Autophagy 59%
  • Cell Death 46%
  • Sedaghatian type Spondylometaphyseal dysplasia 11%
  • Parthanatos 9%
  37 Scopus citations

• Identification and characterization of the CDK1-BMAL1-UHRF1 pathway driving tumor progression

  Wang, D., Wang, F., Wang, S., Chu, L., Tang, D., Chen, P. & Yang, M., Apr 21 2023, In: iScience. 26, 4, 106544.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neoplasms 100%
  • Circadian Clocks 42%
  • Lung Transplantation 40%
  • Growth 34%
  • Transfection 29%
  1 Scopus citations

• Identification of HPCAL1 as a specific autophagy receptor involved in ferroptosis

  Chen, X., Song, X., Li, J., Zhang, R., Yu, C., Zhou, Z., Liu, J., Liao, S., Klionsky, D. J., Kroemer, G., Liu, J., Tang, D. & Kang, R., 2023, In: Autophagy. 19, 1, p. 54-74 21 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hippocalcin 100%
  • Ferroptosis 83%
  • Autophagy 50%
  • Cadherins 38%
  • Protein Kinase C-theta 24%
  41 Scopus citations

• Inhibition of the SLC35B2–TPST2 Axis of Tyrosine Sulfation Attenuates the Growth and Metastasis of Pancreatic Ductal Adenocarcinom

  Cai, X., Li, S., Zeng, X., Xu, M., Wang, Z., Singhi, A. D., Tang, D., Li, S., Yates, N. A., Yang, D. & Xie, W., Jan 2023, In: CMGH. 16, 3, p. 473-495 23 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • protein-tyrosine sulfotransferase 100%
  • Tyrosine 63%
  • Psychological Inhibition 56%
  • Adenocarcinoma 53%
  • Neoplasm Metastasis 42%
  2 Scopus citations

• Liver in infections: a single-cell and spatial transcriptomics perspective

  Zou, J., Li, J., Zhong, X., Tang, D., Fan, X. & Chen, R., Dec 2023, In: Journal of biomedical science. 30, 1, 53.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Clearance 64%
  • Heterogeneity 54%
  • Communication 54%
  • Antigen 49%
  • Liver 30%
  1 Scopus citations

• Mechanisms of alkaliptosis

  Chen, F., Kang, R., Liu, J. & Tang, D., 2023, In: Frontiers in Cell and Developmental Biology. 11, 1213995.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl)benzamide 100%
  • Regulated Cell Death 75%
  • Cell Death 73%
  • Neoplasms 62%
  • Combination Drug Therapy 49%
  1 Scopus citations

• Monitoring Lysosome Function in Ferroptosis

  Chen, F., Kang, R., Tang, D. & Liu, J., 2023, Methods in Molecular Biology. Humana Press Inc., p. 91-102 12 p. (Methods in Molecular Biology; vol. 2712).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Ferroptosis 100%
  • Lysosomes 64%
  • Iron 31%
  • Membrane Lipids 28%
  • Regulated Cell Death 19%
  1 Scopus citations

• Monitoring Mitochondria Function in Ferroptosis

  Chen, F., Liu, J., Tang, D. & Kang, R., 2023, Methods in Molecular Biology. Humana Press Inc., p. 103-115 13 p. (Methods in Molecular Biology; vol. 2712).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Ferroptosis 100%
  • Mitochondria 52%
  • dihydroorotate dehydrogenase 26%
  • Mitophagy 21%
  • Lipid Peroxides 18%

• Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression

  Xia, X., Hu, T., He, X., Liu, Y., Yu, C., Kong, W., Liao, Y., Tang, D., Liu, J. & Huang, H., 2023, In: International Journal of Biological Sciences. 19, 2, p. 377-392 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • neoplasm progression 100%
  • breast neoplasms 76%
  • protein degradation 70%
  • Proteolysis 62%
  • cancer 62%
  2 Scopus citations

• Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis

  Zhang, R., Yu, C., Zeh, H. J., Wang, H., Kroemer, G., Klionsky, D. J., Billiar, T. R., Kang, R. & Tang, D., Dec 12 2023, In: Immunity. 56, 12, p. 2736-2754.e8

  Research output: Contribution to journal › Article › peer-review

  • Aryl Hydrocarbon Receptors 100%
  • Homeostasis 57%
  • Dysbiosis 24%
  • Cyclic GMP 22%
  • DNA 21%
  1 Scopus citations

• Organoids Models of Pancreatic Duct Adenocarcinoma

  Yu, C., Kang, R. & Tang, D., 2023, Methods in Molecular Biology. Humana Press Inc., p. 45-60 16 p. (Methods in Molecular Biology; vol. 2712).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Organoids 100%
  • Pancreatic Ducts 87%
  • Adenocarcinoma 59%
  • Ferroptosis 24%
  • Cell Death 23%
  2 Scopus citations

• Plumbagin is a novel GPX4 protein degrader that induces apoptosis in hepatocellular carcinoma cells

  Yao, L., Yan, D., Jiang, B., Xue, Q., Chen, X., Huang, Q., Qi, L., Tang, D., Chen, X. & Liu, J., Jul 2023, In: Free Radical Biology and Medicine. 203, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • plumbagin 100%
  • Plumbagin 98%
  • Deubiquitinating Enzymes 50%
  • Hepatocellular Carcinoma 48%
  • Apoptosis 36%
  10 Scopus citations

• Preface

  Tang, D. & Kroemer, G., 2023, In: Methods in Molecular Biology. 2712, p. v

  Research output: Contribution to journal › Editorial › peer-review

• Reductive cell death: the other side of the coin

  Zhang, R., Kang, R. & Tang, D., Jul 2023, In: Cancer Gene Therapy. 30, 7, p. 929-931 3 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access
  4 Scopus citations

• SLC25A22 as a Key Mitochondrial Transporter Against Ferroptosis by Producing Glutathione and Monounsaturated Fatty Acids

  Liu, Y., Wang, Y., Lin, Z., Kang, R., Tang, D. & Liu, J., Jul 1 2023, In: Antioxidants and Redox Signaling. 39, 1-3, p. 166-185 20 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ferroptosis 100%
  • Monounsaturated Fatty Acid 90%
  • Monounsaturated Fatty Acids 86%
  • Cell Death 67%
  • Glutathione 57%
  7 Scopus citations

• SQSTM1 is a therapeutic target for infection and sterile inflammation

  Tang, D. & Kang, R., Sep 2023, In: Cytokine. 169, 156317.

  Research output: Contribution to journal › Article › peer-review

  • Inflammation 100%
  • Infections 81%
  • P62 70%
  • Protein 70%
  • Post Translational Protein Processing 58%
  1 Scopus citations

• Targeting deubiquitinases for cancer therapy

  Xue, Q., Tang, D., Chen, X. & Liu, J., Oct 2023, In: Clinical and Translational Discovery. 3, 5, e242.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Deubiquitinating Enzymes 100%
  • Cysteine 62%
  • Neoplasms 23%
  • Application 22%
  • Therapeutics 11%

• Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells

  Ding, W., Wang, J. X., Wu, J. Z., Liu, A. C., Jiang, L. L., Zhang, H. C., Meng, Y., Liu, B. Y., Peng, G. J., Lou, E. Z., Mao, Q., Zhou, H., Tang, D. L., Chen, X., Liu, J. B. & Shi, X. P., Dec 2023, In: Acta Pharmacologica Sinica. 44, 12, p. 2537-2548 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Deubiquitinating Enzymes 100%
  • Fluorouracil 68%
  • Colorectal Neoplasms 57%
  • Cell Proliferation 7%
  • Proteasome Endopeptidase Complex 6%

• Tarlatamab: the promising immunotherapy on its way from the lab to the clinic

  Tang, D. & Kang, R., Jun 30 2023, In: Translational Lung Cancer Research. 12, 6, p. 1335-1357 23 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• The ACSL4 Network Regulates Cell Death and Autophagy in Diseases

  Chen, F., Kang, R., Liu, J. & Tang, D., Jun 2023, In: Biology. 12, 6, 864.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Ferroptosis 100%
  • autophagy 75%
  • Cell Death 67%
  • Autophagy 60%
  • cell death 58%
  6 Scopus citations

• The Dual Role of ACOD1 in Inflammation

  Wu, R., Liu, J., Tang, D. & Kang, R., Aug 2023, In: Journal of Immunology. 211, 4, p. 518-526 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • itaconic acid 100%
  • aconitate decarboxylase 60%
  • Mitochondrial Genes 35%
  • Immune Tolerance 33%
  • Inflammasomes 33%
  2 Scopus citations

• The multifunctional protein HMGB1: 50 years of discovery

  Tang, D., Kang, R., Zeh, H. J. & Lotze, M. T., Dec 2023, In: Nature Reviews Immunology. 23, 12, p. 824-841 18 p.

  Research output: Contribution to journal › Review article › peer-review

  • HMGB1 Protein 100%
  • Nucleic Acids 14%
  • Autoimmunity 14%
  • Biological Phenomena 14%
  • Cytosol 14%
  33 Scopus citations

• The Redox Protein High-Mobility Group Box 1 in Cell Death and Cancer

  Chen, R., Zou, J., Kang, R. & Tang, D., Sep 1 2023, In: Antioxidants and Redox Signaling. 39, 7-9, p. 569-590 22 p.

  Research output: Contribution to journal › Review article › peer-review

  • HMGB1 Protein 100%
  • Cell Death 80%
  • Oxidation-Reduction 72%
  • Protein 31%
  • Subcellular Localization 25%
  3 Scopus citations

• TMEM164 is a new determinant of autophagy-dependent ferroptosis

  Liu, J., Liu, Y., Wang, Y., Li, C., Xie, Y., Klionsky, D. J., Kang, R. & Tang, D., 2023, In: Autophagy. 19, 3, p. 945-956 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ferroptosis 100%
  • Autophagy 60%
  • Autophagosomes 25%
  • Proteins 23%
  • Starvation 22%
  41 Scopus citations

• Tumor-specific GPX4 degradation enhances ferroptosis-initiated antitumor immune response in mouse models of pancreatic cancer

  Li, J., Liu, J., Zhou, Z., Wu, R., Chen, X., Yu, C., Stockwell, B., Kroemer, G., Kang, R. & Tang, D., Nov 1 2023, In: Science translational medicine. 15, 720, eadg3049.

  Research output: Contribution to journal › Article › peer-review

  • Phospholipid Hydroperoxide Glutathione Peroxidase 100%
  • Ferroptosis 97%
  • Pancreatic Neoplasms 58%
  • Immunity 25%
  • Neoplasms 19%
  16 Scopus citations

• TXNDC12 inhibits lipid peroxidation and ferroptosis

  Tang, L., Yu, Y., Deng, W., Liu, J., Wang, Y., Ye, F., Kang, R., Tang, D. & He, Q., Dec 15 2023, In: iScience. 26, 12, 108393.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ferroptosis 100%
  • Endoplasmic Reticulum 17%
  • Regulated Cell Death 14%
  • Activating Transcription Factor 4 13%
  • Thioredoxins 11%
  5 Scopus citations

• Upstream open reading frames mediate autophagy-related protein translation

  Yang, Y., Gatica, D., Liu, X., Wu, R., Kang, R., Tang, D. & Klionsky, D. J., 2023, In: Autophagy. 19, 2, p. 457-473 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Autophagy-Related Proteins 100%
  • Protein Biosynthesis 74%
  • Open Reading Frames 66%
  • Autophagy 66%
  • 5' Untranslated Regions 26%
  3 Scopus citations