The Advanced Imaging Research Center

Research Output

2014

Acetate is a bioenergetic substrate for human glioblastoma and brain metastases

Mashimo, T., Pichumani, K., Vemireddy, V., Hatanpaa, K. J., Singh, D. K., Sirasanagandla, S., Nannepaga, S., Piccirillo, S. G., Kovacs, Z., Foong, C., Huang, Z., Barnett, S., Mickey, B. E., Deberardinis, R. J., Tu, B. P., Maher, E. A. & Bachoo, R. M., Dec 18 2014, In : Cell. 159, 7, p. 1603-1614 12 p.

Research output: Contribution to journalArticle

303 Scopus citations
3 Scopus citations

Active MR-temperature feedback control of dynamic interstitial ultrasound therapy in brain: In vivo experiments and modeling in native and coagulated tissues

N'Djin, W. A., Burtnyk, M., Lipsman, N., Bronskill, M., Kucharczyk, W., Schwartz, M. L. & Chopra, R., Sep 2014, In : Medical physics. 41, 9, 093301.

Research output: Contribution to journalArticle

11 Scopus citations

A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice

Duarte, J. A. G., Carvalho, F., Pearson, M., Horton, J. D., Browning, J. D., Jones, J. G. & Burgess, S. C., Jan 1 2014, In : Journal of lipid research. 55, 12, p. 2541-2553 13 p., A11.

Research output: Contribution to journalArticle

63 Scopus citations

Amide proton transfer imaging of adult diffuse gliomas: Correlation with histopathological grades

Togao, O., Yoshiura, T., Keupp, J., Hiwatashi, A., Yamashita, K., Kikuchi, K., Suzuki, Y., Suzuki, S. O., Iwaki, T., Hata, N., Mizoguchi, M., Yoshimoto, K., Sagiyama, K., Takahashi, M. & Honda, H., Mar 2014, In : Neuro-oncology. 16, 3, p. 441-448 8 p.

Research output: Contribution to journalArticle

160 Scopus citations

A prognostic volumetric threshold of gross tumor volume in head and neck cancer patients treated with radiotherapy

Romesser, P. B., Qureshi, M. M., Subramaniam, R. M., Sakai, O., Jalisi, S. & Truong, M. T., Apr 2014, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 37, 2, p. 154-161 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Arcuate AgRP neurons mediate orexigenic and glucoregulatory actions of ghrelin

Wang, Q., Liu, C., Uchida, A., Chuang, J. C., Walker, A., Liu, T., Osborne-Lawrence, S., Mason, B. L., Mosher, C., Berglund, E. D., Elmquist, J. K. & Zigman, J. M., Feb 1 2014, In : Molecular Metabolism. 3, 1, p. 64-72 9 p.

Research output: Contribution to journalArticle

123 Scopus citations

A self-tuning adaptive controller for 3-D image-guided ultrasound cancer therapy

Goharrizi, A. Y., Kwong, R. H. & Chopra, R., Mar 1 2014, In : IEEE Transactions on Biomedical Engineering. 61, 3, p. 911-919 9 p., 6674991.

Research output: Contribution to journalArticle

3 Scopus citations

Assessment of irradiated brain metastases using dynamic contrast-enhanced magnetic resonance imaging

Almeida-Freitas, D. B., Pinho, M. C., Otaduy, M. C. G., Braga, H. F., Meira-Freitas, D. & Da Costa Leite, C., Jun 2014, In : Neuroradiology. 56, 6, p. 437-443 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Brain PET in the diagnosis of Alzheimer's disease

Marcus, C., Mena, E. & Subramaniam, R. M., Oct 1 2014, In : Clinical nuclear medicine. 39, 10, p. e413-e426

Research output: Contribution to journalReview article

79 Scopus citations

CEST and PARACEST Agents for Molecular Imaging

Evbuomwan, O. M., Terreno, E., Aime, S. & Sherry, A. D., Dec 22 2014, The Chemistry of Molecular Imaging. Wiley-Blackwell, Vol. 9781118093276. p. 225-243 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Clinical/scientific notes

Sakaie, K., Takahashi, M., Sagiyama, K., Dimitrov, I., Frohman, T., Remington, G., Frohman, E. & Fox, R. J., Jan 14 2014, In : Neurology. 82, 2, p. 182-183 2 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

Clinical proton MR spectroscopy in central nervous system disorders

Öz, G., Alger, J. R., Barker, P. B., Bartha, R., Bizzi, A., Boesch, C., Bolan, P. J., Brindle, K. M., Cudalbu, C., Dinçer, A., Dydak, U., Emir, U. E., Frahm, J., Gilberto González, R., Gruber, S., Gruetter, R., Gupta, R. K., Heerschap, A., Henning, A., Hetherington, H. P. & 31 others, Howe, F. A., Hüppi, P. S., Hurd, R. E., Kantarci, K., Klomp, D. W. J., Kreis, R., Kruiskamp, M. J., Leach, M. O., Lin, A. P., Luijten, P. R., Marjańska, M., Maudsley, A. A., Meyerhoff, D. J., Mountford, C. E., Nelson, S. J., Pamir, N., Pan, J. W., Peet, A. C., Poptani, H., Poptani, H., Posse, S., Pouwels, P. J. W., Ratai, E. M., Ross, B. D., Scheenen, T. W. J., Schuster, C., Smith, I. C. P., Soher, B. J., Tkáč, I., Vigneron, D. B. & Kauppinen, R. A., Mar 5 2014, In : RADIOLOGY. 270, 3, p. 658-679 22 p.

Research output: Contribution to journalReview article

255 Scopus citations

Development of robust/predictive control strategies for image-guided ablative treatments using a minimally invasive ultrasound applicator

Goharrizi, A. Y., Kwong, R. & Chopra, R., Nov 1 2014, In : International Journal of Hyperthermia. 30, 7, p. 438-446 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Dynamic metabolic imaging of hyperpolarized [2-13C]pyruvate using spiral chemical shift imaging with alternating spectral band excitation

Josan, S., Hurd, R., Park, J. M., Yen, Y. F., Watkins, R., Pfefferbaum, A., Spielman, D. & Mayer, D., Jun 2014, In : Magnetic resonance in medicine. 71, 6, p. 2051-2058 8 p.

Research output: Contribution to journalArticle

23 Scopus citations
3 Scopus citations

Fat and iron quantification in the liver: Past, present, and future

Yokoo, T. & Browning, J. D., Apr 2014, In : Topics in Magnetic Resonance Imaging. 23, 2, p. 129-150 22 p.

Research output: Contribution to journalArticle

8 Scopus citations

Fat and iron quantification in the liver: past, present, and future.

Yokoo, T. & Browning, J. D., Apr 2014, In : Topics in magnetic resonance imaging : TMRI. 23, 2, p. 73-94 22 p.

Research output: Contribution to journalReview article

18 Scopus citations

FDG PET/CT imaging of oropharyngeal squamous cell carcinoma: Characteristics of human papillomavirus-positive and -negative tumors

Tahari, A. K., Alluri, K. C., Quon, H., Koch, W., Wahl, R. L. & Subramaniam, R. M., Mar 2014, In : Clinical nuclear medicine. 39, 3, p. 225-231 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

FDG-PET/CT in the evaluation of paraneoplastic neurologic syndromes

Sherry, S. J., Tahari, A. K., Mirpour, S., Colucci, A. & Subramaniam, R. M., Feb 1 2014, In : Imaging in Medicine. 6, 1, p. 117-126 10 p.

Research output: Contribution to journalReview article

1 Scopus citations

FDG PET/CT in the management of colorectal and anal cancers

Agarwa, A., Marcus, C., Xiao, J., Nene, P., Kachnic, L. A. & Subramaniam, R. M., Nov 1 2014, In : American Journal of Roentgenology. 203, 5, p. 1109-1119 11 p.

Research output: Contribution to journalReview article

30 Scopus citations

FDG PET/CT in the management of nasopharyngeal carcinoma

Mohandas, A., Marcus, C., Kang, H., Truong, M. T. & Subramaniam, R. M., Aug 2014, In : American Journal of Roentgenology. 203, 2, p. W146-W157

Research output: Contribution to journalReview article

18 Scopus citations

FDG PET metabolic tumor volume segmentation and pathologic volume of primary human solid tumors

Sridhar, P., Mercier, G., Tan, J., Truong, M. T., Daly, B. & Subramaniam, R. M., May 2014, In : American Journal of Roentgenology. 202, 5, p. 1114-1119 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

FDG volumetric parameters and survival outcomes after definitive chemoradiotherapy in patients with recurrent head and neck squamous cell carcinoma

Paidpally, V., Chirindel, A., Chung, C. H., Richmon, J., Koch, W., Quon, H. & Subramaniam, R. M., Aug 2014, In : American Journal of Roentgenology. 203, 2, p. W139-W145

Research output: Contribution to journalArticle

31 Scopus citations

Follow-up or surveillance 18F-FDG PET/CT and survival outcome in lung cancer patients

Antoniou, A. J., Marcus, C., Tahari, A. K., Wahl, R. L. & Subramaniam, R. M., Jul 1 2014, In : Journal of Nuclear Medicine. 55, 7, p. 1062-1068 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Funding resources for junior radiology clinical scientists: where to look?

Subramaniam, R. M., Jan 1 2014, In : Pediatric Radiology. 44, 11, p. 1339-1341 3 p.

Research output: Contribution to journalReview article

22 Scopus citations

Geometric Distortion in Diffusion-weighted MR Imaging of the Prostate-Contributing Factors and Strategies for Improvement

Donato, F., Costa, D. N., Yuan, Q., Rofsky, N. M., Lenkinski, R. E. & Pedrosa, I., Jun 2014, In : Academic radiology. 21, 6, p. 817-823 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Head and neck PET/CT: Therapy response interpretation criteria (Hopkins criteria) - Interreader reliability, accuracy, and survival outcomes

Marcus, C., Ciarallo, A., Tahari, A. K., Mena, E., Koch, W., Wahl, R. L., Kiess, A. P., Kang, H. & Subramaniam, R. M., Sep 1 2014, In : Journal of Nuclear Medicine. 55, 9, p. 1411-1416 6 p.

Research output: Contribution to journalArticle

82 Scopus citations

Head and neck squamous cell cancer (stages III and IV) induction chemotherapy assessment: Value of FDG volumetric imaging parameters

Yu, J., Cooley, T., Truong, M. T., Mercier, G. & Subramaniam, R. M., Feb 1 2014, In : Journal of Medical Imaging and Radiation Oncology. 58, 1, p. 18-24 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Hepatocyte toll-like receptor 4 regulates obesity-induced inflammation and insulin resistance

Jia, L., Vianna, C. R., Fukuda, M., Berglund, E. D., Liu, C., Tao, C., Sun, K., Liu, T., Harper, M. J., Lee, C. E., Lee, S., Scherer, P. E. & Elmquist, J. K., May 12 2014, In : Nature communications. 5, 3878.

Research output: Contribution to journalArticle

127 Scopus citations
49 Scopus citations

Increased de novo lipogenesis is a distinct characteristic of individuals with nonalcoholic fatty liver disease

Lambert, J. E., Ramos-Roman, M. A., Browning, J. D. & Parks, E. J., Mar 2014, In : Gastroenterology. 146, 3, p. 726-735 10 p.

Research output: Contribution to journalArticle

322 Scopus citations
18 Scopus citations

Interreader agreement and variability of FDG PET volumetric parameters in human solid tumors

Paidpally, V., Mercier, G., Shah, B. A., Senthamizhchelvan, S. & Subramaniam, R. M., Feb 1 2014, In : American Journal of Roentgenology. 202, 2, p. 406-412 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
110 Scopus citations

In vivo detection of citrate in brain tumors by 1H magnetic resonance spectroscopy at 3T

Choi, C., Ganji, S. K., Madan, A., Hulsey, K. M., An, Z., Zhang, S., Pinho, M. C., Deberardinis, R. J., Bachoo, R. M. & Maher, E. A., Aug 2014, In : Magnetic resonance in medicine. 72, 2, p. 316-323 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

In vivo imaging of paraCEST agents using frequency labeled exchange transfer MRI

Lin, C. Y., Yadav, N. N., Ratnakar, J., Sherry, A. D. & Van Zijl, P. C. M., Jan 2014, In : Magnetic resonance in medicine. 71, 1, p. 286-293 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treatedwith cediranib in combinationwith chemoradiation

Pinho, M. C., Polaskova, P., Kalpathy-Cramer, J., Jennings, D., Emblem, K. E., Jain, R. K., Rosen, B. R., Wen, P. Y., Sorensen, A. G., Batchelor, T. T. & Gerstner, E. R., 2014, In : Oncologist. 19, 1, p. 75-81 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Machine learning in preoperative glioma MRI: Survival associations by perfusion-based support vector machine outperforms traditional MRI

Emblem, K. E., Due-Tonnessen, P., Hald, J. K., Bjornerud, A., Pinho, M. C., Scheie, D., Schad, L. R., Meling, T. R. & Zoellner, F. G., Jul 2014, In : Journal of Magnetic Resonance Imaging. 40, 1, p. 47-54 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Maximizing T2-exchange in Dy3+DOTA-(amide) X chelates: Fine-tuning the water molecule exchange rate for enhanced T2 contrast in MRI

Soesbe, T. C., Ratnakar, S. J., Milne, M., Zhang, S., Do, Q. N., Kovacs, Z. & Sherry, A. D., Mar 2014, In : Magnetic resonance in medicine. 71, 3, p. 1179-1185 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver

Baskin, K. K., Grueter, C. E., Kusminski, C. M., Holland, W. L., Bookout, A. L., Satapati, S., Kong, Y. M., Burgess, S. C., Malloy, C. R., Scherer, P. E., Newgard, C. B., Bassel-Duby, R. & Olson, E. N., Dec 1 2014, In : EMBO Molecular Medicine. 6, 12, p. 1610-1621 12 p.

Research output: Contribution to journalArticle

40 Scopus citations

Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia

Berglund, E. D., Liu, T., Kong, X., Sohn, J. W., Vong, L., Deng, Z., Lee, C. E., Lee, S., Williams, K. W., Olson, D. P., Scherer, P. E., Lowell, B. B. & Elmquist, J. K., Jul 2014, In : Nature neuroscience. 17, 7, p. 911-913 3 p.

Research output: Contribution to journalArticle

73 Scopus citations

Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion

Vigueira, P. A., McCommis, K. S., Schweitzer, G. G., Remedi, M. S., Chambers, K. T., Fu, X., McDonald, W. G., Cole, S. L., Colca, J. R., Kletzien, R. F., Burgess, S. C. & Finck, B. N., Jun 26 2014, In : Cell Reports. 7, 6, p. 2042-2053 12 p.

Research output: Contribution to journalArticle

47 Scopus citations
8 Scopus citations

Multi-temporal radar backscattering measurements and modelling of rice fields using a multi-frequency (L, S, C, and X) scatterometer

Jia, M., Tong, L., Zhang, Y., Chen, Y. & Chopra, R., Feb 2014, In : International Journal of Remote Sensing. 35, 4, p. 1253-1271 19 p.

Research output: Contribution to journalArticle

8 Scopus citations

Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects

Mullen, A. R., Hu, Z., Shi, X., Jiang, L., Boroughs, L. K., Kovacs, Z., Boriack, R., Rakheja, D., Sullivan, L. B., Linehan, W. M., Chandel, N. S. & DeBerardinis, R. J., Jun 12 2014, In : Cell Reports. 7, 5, p. 1679-1690 12 p.

Research output: Contribution to journalArticle

153 Scopus citations

Perceived misinterpretation rates in oncologic 18F-FDG PET/CT studies: A survey of referring physicians

Karantanis, D., Kalkanis, D., Czernin, J., Herrmann, K., Pomykala, K. L., Bogsrud, T. V., Subramaniam, R. M., Lowe, V. J. & Allen-Auerbach, M. S., Dec 1 2014, In : Journal of Nuclear Medicine. 55, 12, p. 1925-1929 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

PET/CT imaging and human papilloma virus-positive oropharyngeal squamous cell cancer: Evolving clinical imaging paradigm

Subramaniam, R. M., Alluri, K. C., Tahari, A. K., Aygun, N. & Quon, H., Mar 1 2014, In : Journal of Nuclear Medicine. 55, 3, p. 431-438 8 p.

Research output: Contribution to journalArticle

24 Scopus citations