Research output per year
Research output per year
- 1 - 50 out of 246 results
Search results
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2024
Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability
Deja, S., Fletcher, J., Kim, C-W., Kucejova, B., Fu, X., Mizerska, M., Villegas, M., Pudelko-Malik, N., Browder, N., Inigo-Vollmer, M., Menezes, C. J., Mishra, P., Berglund, E. D., Browning, J. D., Thyfault, J. P., Young, J. D., Horton, J. D. & Burgess, S. C., 2024, (Accepted/In press) In: Cell Metabolism.Research output: Contribution to journal › Article › peer-review
Open Access -
Impact of Pretreatment Weight Loss on Radiotherapy Utilization and Clinical Outcomes in Non–Small Cell Lung Cancer
Alvarez, C. M., Aliru, M., Gannavarapu, B. S., Song, T., Gilmore, L. A., Olaechea, S., Gomez, D. R., Ahn, C., Infante, R. E. & Iyengar, P., Feb 1 2024, In: American Journal of Clinical Oncology: Cancer Clinical Trials. 47, 2, p. 49-55 7 p.Research output: Contribution to journal › Article › peer-review
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2023
25-Hydroxycholesterol exacerbates vascular leak during acute lung injury
Madenspacher, J. H., Morrell, E. D., McDonald, J. G., Thompson, B. M., Li, Y., Birukov, K. G., Birukova, A. A., Stapleton, R. D., Alejo, A., Karmaus, P. W., Meacham, J. M., Rai, P., Mikacenic, C., Wurfel, M. M. & Fessler, M. B., Apr 10 2023, In: JCI Insight. 8, 7, e155448.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
A Concerted Mechanism Involving ACAT and SREBPs By which Oxysterols Deplete Accessible Cholesterol To Restrict Microbial Infection
Heisler, D. B., Johnson, K. A., Ma, D., Ohlson, M. B., Zhang, L., Tran, M., Corley, C. D., Abrams, M. E., McDonald, J. G., Schoggins, J. W., Alto, N. M. & Radhakrishnan, A., Jan 2023, In: eLife. 12, e83534.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Association of Vaginal Progesterone Treatment With Prevention of Recurrent Preterm Birth
Nelson, D. B., Lafferty, A., Venkatraman, C., Mcdonald, J. G., Eckert, K. M., Mcintire, D. D. & Spong, C. Y., Apr 1 2023, In: Obstetrical and Gynecological Survey. 78, 4, p. 201-203 3 p.Research output: Contribution to journal › Comment/debate › peer-review
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Cutaneous Hormone Production Is Distinct between Anatomical Sites and between Males and Females
Pineider, J., Eckert, K. M., McDonald, J. G. & Harris-Tryon, T., Apr 2023, In: Journal of Investigative Dermatology. 143, 4, p. 596-601 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice
Yiew, N. K. H., Deja, S., Ferguson, D., Cho, K., Jarasvaraparn, C., Jacome-Sosa, M., Lutkewitte, A. J., Mukherjee, S., Fu, X., Singer, J. M., Patti, G. J., Burgess, S. C. & Finck, B. N., Nov 17 2023, In: iScience. 26, 11, 108196.Research output: Contribution to journal › Article › peer-review
Open Access -
Endogenous and Therapeutic 25-Hydroxycholesterols May Worsen Early SARS-CoV-2 Pathogenesis in Mice
Fessler, M. B., Madenspacher, J. H., Baker, P. J., Hilligan, K. L., Bohrer, A. C., Castro, E., Meacham, J., Chen, S. H., Johnson, R. F., McDonald, J. G., Martin, N. P., Tucker, C. J., Mahapatra, D., Cesta, M. & Mayer-Barber, K. D., Dec 2023, In: American journal of respiratory cell and molecular biology. 69, 6, p. 638-648 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization
Onodera, T., Wang, M. Y., Rutkowski, J. M., Deja, S., Chen, S., Balzer, M. S., Kim, D. S., Sun, X., An, Y. A., Field, B. C., Lee, C., Matsuo, E. I., Mizerska, M., Sanjana, I., Fujiwara, N., Kusminski, C. M., Gordillo, R., Gautron, L., Marciano, D. K., Hu, M. C., & 4 others, Dec 2023, In: Nature communications. 14, 1, 6531.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Limiting mitochondrial plasticity by targeting DRP1 induces metabolic reprogramming and reduces breast cancer brain metastases
Parida, P. K., Marquez-Palencia, M., Ghosh, S., Khandelwal, N., Kim, K., Nair, V., Liu, X. Z., Vu, H. S., Zacharias, L. G., Gonzalez-Ericsson, P. I., Sanders, M. E., Mobley, B. C., McDonald, J. G., Lemoff, A., Peng, Y., Lewis, C., Vale, G., Halberg, N., Arteaga, C. L., Hanker, A. B., & 2 others, Jun 2023, In: Nature Cancer. 4, 6, p. 893-907 15 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice
Rome, F. I., Shobert, G. L., Voigt, W. C., Stagg, D. B., Puchalska, P., Burgess, S. C., Crawford, P. A. & Hughey, C. C., Jan 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 324, 1, p. E9-E23Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Macrophage-Derived 25-Hydroxycholesterol Promotes Vascular Inflammation, Atherogenesis, and Lesion Remodeling
Canfrán-Duque, A., Rotllan, N., Zhang, X., Andrés-Blasco, I., Thompson, B. M., Sun, J., Price, N. L., Fernández-Fuertes, M., Fowler, J. W., Gómez-Coronado, D., Sessa, W. C., Giannarelli, C., Schneider, R. J., Tellides, G., McDonald, J. G., Fernández-Hernando, C. & Suárez, Y., Jan 31 2023, In: Circulation. 147, 5, p. 388-408 21 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Myocardial steatosis impairs left ventricular diastolic–systolic coupling in healthy humans
Oneglia, A. P., Szczepaniak, L. S., Jaffery, M. F., Cipher, D. J., McDonald, J. G., Haykowsky, M. J., Moreau, K. L., Clegg, D. J., Zaha, V. & Nelson, M. D., Apr 15 2023, In: Journal of Physiology. 601, 8, p. 1371-1382 12 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Persistent fasting lipogenesis links impaired ketogenesis with citrate synthesis in humans with nonalcoholic fatty liver
Fu, X., Fletcher, J. A., Deja, S., Inigo-Vollmer, M., Burgess, S. C. & Browning, J. D., May 1 2023, In: Journal of Clinical Investigation. 133, 9, e167442.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Preanalytics for Lipidomics Analysis
Vale, G. & McDonald, J. G., Jan 1 2023, Mass Spectrometry for Lipidomics: Methods and Applications. wiley, p. 15-40 26 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Race, Ethnicity, and Socioeconomic Factors as Determinants of Cachexia Incidence and Outcomes in a Retrospective Cohort of Patients with Gastrointestinal Tract Cancer
Olaechea, S., Sarver, B., Liu, A., Gilmore, L. A., Alvarez, C., Iyengar, P. & Infante, R., Jul 1 2023, In: JCO Oncology Practice. 19, 7, p. 493-500 8 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Racial, Ethnic, and Socioeconomic Characteristics Independently Predict for Cachexia Risk and Associated Survival Outcomes in Stage IV NSCLC: A Brief Report
Olaechea, S., Liu, A., Sarver, B., Gilmore, L. A., Alvarez, C., Yazdanbakhsh, K., Infante, R. & Iyengar, P., Apr 2023, In: JTO Clinical and Research Reports. 4, 4, 100496.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Regulated adipose tissue-specific expression of human AGPAT2 in lipodystrophic Agpat2-null mice results in regeneration of adipose tissue
Agarwal, A. K., Tunison, K., Vale, G., McDonald, J. G., Li, X., Scherer, P. E., Horton, J. D. & Garg, A., Oct 20 2023, In: iScience. 26, 10, 107806.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Risk Enhancing Factors and Coronary Artery Calcium Strengthen Atherosclerotic Cardiovascular Disease Risk Estimation
Saleh, D., Grundy, S. M. & Stone, N. J., Feb 15 2023, In: American Journal of Cardiology. 189, p. 38-40 3 p.Research output: Contribution to journal › Editorial › peer-review
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Selective and brain-penetrant lanosterol synthase inhibitors target glioma stem-like cells by inducing 24(S),25-epoxycholesterol production
Nguyen, T. P., Wang, W., Sternisha, A. C., Corley, C. D., Wang, H. Y. L., Wang, X., Ortiz, F., Lim, S. K., Abdullah, K. G., Parada, L. F., Williams, N. S., McBrayer, S. K., McDonald, J. G., De Brabander, J. K. & Nijhawan, D., Feb 16 2023, In: Cell Chemical Biology. 30, 2, p. 214-229.e18Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Statin therapy for primary prevention in men: What is the role for coronary artery calcium?
Grundy, S. M., Wang, J. & Vega, G. L., Jan 1 2023, In: Journal of Clinical Lipidology. 17, 1, p. 12-18 7 p.Research output: Contribution to journal › Editorial › peer-review
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Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate
Chen, H., Ahmed, S., Zhao, H., Elghobashi-Meinhardt, N., Dai, Y., Kim, J. H., McDonald, J. G., Li, X. & Lee, C. H., Jun 8 2023, In: Cell. 186, 12, p. 2644-2655.e16Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Tumor loss-of-function mutations in STK11/LKB1 induce cachexia
Iyengar, P., Gandhi, A. Y., Granados, J., Guo, T., Gupta, A., Yu, J., Llano, E. M., Zhang, F., Gao, A., Kandathil, A., Williams, D., Gao, B., Girard, L., Malladi, V. S., Shelton, J. M., Evers, B. M., Hannan, R., Ahn, C., Minna, J. D. & Infante, R. E., 2023, In: JCI Insight. 8, 8, e165419.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2022
A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience
Wang, C., Wang, B., Pandey, T., Long, Y., Zhang, J., Oh, F., Sima, J., Guo, R., Liu, Y., Zhang, C., Mukherjee, S., Bassik, M., Lin, W., Deng, H., Vale, G., McDonald, J. G., Shen, K. & Ma, D. K., Dec 2022, In: Nature communications. 13, 1, 6805.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
A preponderance of gastrointestinal cancer patients transition into cachexia syndrome
Gilmore, L. A., Olaechea, S., Gilmore, B. W., Gannavarapu, B. S., Alvarez, C. M., Ahn, C., Iyengar, P. & Infante, R. E., Dec 2022, In: Journal of Cachexia, Sarcopenia and Muscle. 13, 6, p. 2920-2931 12 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Association of demographic and health characteristics with circulating oxysterol concentrations
Passarelli, M. N., McDonald, J. G., Thompson, B. M., Arega, E. A., Palys, T. J., Rees, J. R., Barry, E. L. & Baron, J. A., May 1 2022, In: Journal of Clinical Lipidology. 16, 3, p. 345-355 11 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Association of Vaginal Progesterone Treatment With Prevention of Recurrent Preterm Birth
Nelson, D. B., Lafferty, A., Venkatraman, C., McDonald, J. G., Eckert, K. M., McIntire, D. D. & Spong, C. Y., Oct 3 2022, In: JAMA Network Open. 5, 10, p. e2237600Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Associations of Prior Chronic Use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Glucocorticoids With Cachexia Incidence and Survival
Olaechea, S., Gilmore, A., Alvarez, C., Gannavarapu, B. S., Infante, R. & Iyengar, P., Jun 7 2022, In: Frontiers in Oncology. 12, 922418.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Author Correction: Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer (Nature Communications, (2022), 13, 1, (4327), 10.1038/s41467-022-31963-4)
Bartolacci, C., Andreani, C., Vale, G., Berto, S., Melegari, M., Crouch, A. C., Baluya, D. L., Kemble, G., Hodges, K., Starrett, J., Politi, K., Starnes, S. L., Lorenzini, D., Raso, M. G., Solis Soto, L. M., Behrens, C., Kadara, H., Gao, B., Wistuba, I. I., Minna, J. D., & 2 others, Dec 2022, In: Nature communications. 13, 1, 4640.Research output: Contribution to journal › Comment/debate › peer-review
Open Access3 Scopus citations -
Cachexia is Prevalent in Patients With Hepatocellular Carcinoma and Associated With Worse Prognosis
Rich, N. E., Phen, S., Desai, N., Mittal, S., Yopp, A. C., Yang, J. D., Marrero, J. A., Iyengar, P., Infante, R. E. & Singal, A. G., May 2022, In: Clinical Gastroenterology and Hepatology. 20, 5, p. e1157-e1169Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Cytokine-Mediated STAT3 Transcription Supports ATGL/CGI-58-Dependent Adipocyte Lipolysis in Cancer Cachexia
Gandhi, A. Y., Yu, J., Gupta, A., Guo, T., Iyengar, P. & Infante, R. E., Jun 15 2022, In: Frontiers in Oncology. 12, 841758.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Desmosterol and 7-dehydrocholesterol concentrations in post mortem brains of depressed people: The role of trazodone
Cenik, B., Palka, J. M., Thompson, B. M., McDonald, J. G., Tamminga, C. A., Cenik, C. & Brown, E. S., Dec 2022, In: Translational psychiatry. 12, 1, 139.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Erratum: Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids (Cell Reports (2022) 39(4), (S2211124722004946), (10.1016/j.celrep.2022.110733))
Martino, M. R., Gutiérrez-Aguilar, M., Yiew, N. K. H., Lutkewitte, A. J., Singer, J. M., McCommis, K. S., Ferguson, D., Liss, K. H. H., Yoshino, J., Renkemeyer, M. K., Smith, G. I., Cho, K., Fletcher, J. A., Klein, S., Patti, G. J., Burgess, S. C. & Finck, B. N., Nov 15 2022, In: Cell Reports. 41, 7, 111633.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
FAF1 blocks ferroptosis by inhibiting peroxidation of polyunsaturated fatty acids
Cui, S., Simmons, G., Vale, G., Deng, Y., Kim, J., Kim, H., Zhang, R., McDonald, J. G. & Ye, J., Apr 26 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 17, 2107189119.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Guidelines for the management of hyperlipidemia: How can clinicians effectively implement them?
Dembowski, E., Freedman, I., Grundy, S. M. & Stone, N. J., Nov 1 2022, In: Progress in Cardiovascular Diseases. 75, p. 4-11 8 p.Research output: Contribution to journal › Review article › peer-review
8 Scopus citations -
Hepatic TM6SF2 Is Required for Lipidation of VLDL in a Pre-Golgi Compartment in Mice and Rats
Luo, F., Smagris, E., Martin, S. A., Vale, G., McDonald, J. G., Fletcher, J. A., Burgess, S. C., Hobbs, H. H. & Cohen, J. C., Jan 2022, In: CMGH. 13, 3, p. 879-899 21 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
INCA 2.0: A tool for integrated, dynamic modeling of NMR- and MS-based isotopomer measurements and rigorous metabolic flux analysis
Rahim, M., Ragavan, M., Deja, S., Merritt, M. E., Burgess, S. C. & Young, J. D., Jan 2022, In: Metabolic Engineering. 69, p. 275-285 11 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol
Trinh, M. N., Brown, M. S., Seemann, J., Vale, G., McDonald, J. G., Goldstein, J. L. & Lu, F., Jan 11 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 2, e2120411119.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Intracellular lipid surveillance by small G protein geranylgeranylation
Watterson, A., Tatge, L., Wajahat, N., Arneaud, S. L. B., Solano Fonseca, R., Beheshti, S. T., Metang, P., Mihelakis, M., Zuurbier, K. R., Corley, C. D., Dehghan, I., McDonald, J. G. & Douglas, P. M., May 26 2022, In: Nature. 605, 7911, p. 736-740 5 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Introducing the Lipidomics Minimal Reporting Checklist
McDonald, J. G., Ejsing, C. S., Kopczynski, D., Holčapek, M., Aoki, J., Arita, M., Arita, M., Baker, E. S., Bertrand-Michel, J., Bowden, J. A., Brügger, B., Ellis, S. R., Fedorova, M., Griffiths, W. J., Han, X., Hartler, J., Hoffmann, N., Koelmel, J. P., Köfeler, H. C., Mitchell, T. W., & 12 others, Sep 2022, In: Nature Metabolism. 4, 9, p. 1086-1088 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access31 Scopus citations -
Krebs takes a turn at cell differentiation
Deja, S., Crawford, P. A. & Burgess, S. C., May 3 2022, In: Cell Metabolism. 34, 5, p. 658-660 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access6 Scopus citations -
Loss of heat shock factor initiates intracellular lipid surveillance by actin destabilization
Watterson, A., Arneaud, S. L. B., Wajahat, N., Wall, J. M., Tatge, L., Beheshti, S. T., Mihelakis, M., Cheatwood, N. Y., McClendon, J., Ghorashi, A., Dehghan, I., Corley, C. D., McDonald, J. G. & Douglas, P. M., Oct 18 2022, In: Cell Reports. 41, 3, 111493.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity
Zhang, Z., Xun, Y., Rong, S., Yan, L., SoRelle, J. A., Li, X., Tang, M., Keller, K., Ludwig, S., Moresco, E. M. Y. & Beutler, B., Dec 2022, In: Nature communications. 13, 1, 4136.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Managing Atherosclerotic Cardiovascular Risk in Young Adults: JACC State-of-the-Art Review
Stone, N. J., Smith, S. C., Orringer, C. E., Rigotti, N. A., Navar, A. M., Khan, S. S., Jones, D. W., Goldberg, R., Mora, S., Blaha, M., Pencina, M. J. & Grundy, S. M., Mar 1 2022, In: Journal of the American College of Cardiology. 79, 8, p. 819-836 18 p.Research output: Contribution to journal › Review article › peer-review
Open Access67 Scopus citations -
Prevalence and significance of risk enhancing biomarkers in the United States population at intermediate risk for atherosclerotic disease
Vega, G. L., Wang, J. & Grundy, S. M., Jan 1 2022, In: Journal of Clinical Lipidology. 16, 1, p. 66-74 9 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Primary Tumor Fluorine‐18 Fluorodeoxydglucose (18F‐FDG) Is Associated With Cancer-Associated Weight Loss in Non-Small Cell Lung Cancer (NSCLC) and Portends Worse Survival
Olaechea, S., Gannavarapu, B. S., Alvarez, C., Gilmore, A., Sarver, B., Xie, D., Infante, R. & Iyengar, P., Jun 24 2022, In: Frontiers in Oncology. 12, 900712.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Repeated trans-arterial treatments of LDL-DHA nanoparticles induce multiple pathways of tumor cell death in hepatocellular carcinoma bearing rats
Wang, Y., Li, J., Vale, G. D. D., Chaudhary, J., Anwar, A., McDonald, J. G., Qin, T., Zhang, H. & Corbin, I. R., Nov 24 2022, In: Frontiers in Oncology. 12, 1052221.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids
Martino, M. R., Gutiérrez-Aguilar, M., Yiew, N. K. H., Lutkewitte, A. J., Singer, J. M., McCommis, K. S., Ferguson, D., Liss, K. H. H., Yoshino, J., Renkemeyer, M. K., Smith, G. I., Cho, K., Fletcher, J. A., Klein, S., Patti, G. J., Burgess, S. C. & Finck, B. N., Apr 26 2022, In: Cell Reports. 39, 4, 110733.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Statin Intolerance and Noncompliance: An Empiric Approach
Grundy, S. M. & Vega, G. L., Mar 2022, In: American Journal of Medicine. 135, 3, p. 318-323 6 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access6 Scopus citations -
Statin therapy for primary prevention in women: What is the role for coronary artery calcium?
Grundy, S. M. & Vega, G. L., 2022, (Accepted/In press) In: Journal of Clinical Lipidology.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations