The Nancy B. and Jake L. Hamon Center for Therapeutic Oncology Research

Research Output

2020

A Proteomic Connectivity Map for Characterizing the Tumor Adaptive Response to Small Molecule Chemical Perturbagens

Zi, Z., Zhang, Y., Zhang, P., Ding, Q., Chu, M., Chen, Y., Minna, J. D. & Yu, Y., Jan 17 2020, In : ACS chemical biology. 15, 1, p. 140-150 11 p.

Research output: Contribution to journalArticle

AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells

Lotsberg, M. L., Wnuk-Lipinska, K., Terry, S., Tan, T. Z., Lu, N., Trachsel-Moncho, L., Røsland, G. V., Siraji, M. I., Hellesøy, M., Rayford, A., Jacobsen, K., Ditzel, H. J., Vintermyr, O. K., Bivona, T. G., Minna, J., Brekken, R. A., Baguley, B., Micklem, D., Akslen, L. A., Gausdal, G. & 5 others, Simonsen, A., Thiery, J. P., Chouaib, S., Lorens, J. B. & Engelsen, A. S. T., Jan 1 2020, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Open Access

RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

Yenerall, P., Das, A. K., Wang, S., Kollipara, R. K., Li, L. S., Villalobos, P., Flaming, J., Lin, Y. F., Huffman, K., Timmons, B. C., Gilbreath, C., Sonavane, R., Kinch, L. N., Rodriguez-Canales, J., Moran, C., Behrens, C., Hirasawa, M., Takata, T., Murakami, R., Iwanaga, K. & 6 others, Chen, B. P. C., Grishin, N. V., Raj, G. V., Wistuba, I. I., Minna, J. D. & Kittler, R., Jan 16 2020, In : Cell Chemical Biology. 27, 1, p. 105-121.e14

Research output: Contribution to journalArticle

1 Scopus citations

SLC43A3 is a biomarker of sensitivity to the telomeric DNA damage mediator 6-thio-2′-deoxyguanosine

Mender, I., Batten, K., Peyton, M., Vemula, A., Cornelius, C., Girard, L., Gao, B., Minna, J. D. & Shay, J. W., Mar 1 2020, In : Cancer research. 80, 5, p. 929-936 8 p.

Research output: Contribution to journalArticle

Ubiquitin C-terminal hydrolase-L1 has prognostic relevance and is a therapeutic target for high-grade neuroendocrine lung cancers

Shimada, Y., Kudo, Y., Maehara, S., Matsubayashi, J., Otaki, Y., Kajiwara, N., Ohira, T., Minna, J. D. & Ikeda, N., Feb 1 2020, In : Cancer Science. 111, 2, p. 610-620 11 p.

Research output: Contribution to journalArticle

Open Access
2019

AIF: an acquired metabolic liability in lung cancer

Faubert, B., DeBerardinis, R. J. & Minna, J. D., Aug 1 2019, In : Cell Research. 29, 8, p. 607-608 2 p.

Research output: Contribution to journalArticle

Open Access

Artificial intelligence in lung cancer pathology image analysis

Wang, S., Yang, D. M., Rong, R., Zhan, X., Fujimoto, J., Liu, H., Minna, J., Wistuba, I. I., Xie, Y. & Xiao, G., Nov 2019, In : Cancers. 11, 11, 1673.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data (Nature Reviews Cancer, (2019), 19, 5, (289-297), 10.1038/s41568-019-0133-9)

Rudin, C. M., Poirier, J. T., Byers, L. A., Dive, C., Dowlati, A., George, J., Heymach, J. V., Johnson, J. E., Lehman, J. M., MacPherson, D., Massion, P. P., Minna, J. D., Oliver, T. G., Quaranta, V., Sage, J., Thomas, R. K., Vakoc, C. R. & Gazdar, A. F., Jan 1 2019, In : Nature Reviews Cancer.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & DeBerardinis, R. J., May 16 2019, In : Nature. 569, 7756, p. E4

Research output: Contribution to journalComment/debate

Open Access

Checkpoint Inhibitor Pneumonitis: Too Clinically Serious For Benefit?

Le, T., Minna, J. D. & Gerber, D. E., Mar 1 2019, In : Journal of Thoracic Oncology. 14, 3, p. 332-335 4 p.

Research output: Contribution to journalEditorial

2 Scopus citations

ClickGene: An open cloud-based platform for big pan-cancer data genome-wide association study, visualization and exploration

Bi, J. H., Tong, Y. F., Qiu, Z. W., Yang, X. F., Minna, J., Gazdar, A. F. & Song, K., Jun 26 2019, In : BioData Mining. 12, 1, 12.

Research output: Contribution to journalArticle

Open Access

ConvPath: A software tool for lung adenocarcinoma digital pathological image analysis aided by a convolutional neural network

Wang, S., Wang, T., Yang, L., Yang, D. M., Fujimoto, J., Yi, F., Luo, X., Yang, Y., Yao, B., Lin, S. Y., Moran, C., Kalhor, N., Weissferdt, A., Minna, J., Xie, Y., Wistuba, I. I., Mao, Y. & Xiao, G., Dec 2019, In : EBioMedicine. 50, p. 103-110 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Correction: LCE: an open web portal to explore gene expression and clinical associations in lung cancer (Oncogene, (2019), 38, 14, (2551-2564), 10.1038/s41388-018-0588-2)

Cai, L., Lin, S. Y., Girard, L., Zhou, Y., Yang, L., Ci, B., Zhou, Q., Luo, D., Yao, B., Tang, H., Allen, J., Huffman, K., Gazdar, A. F., Heymach, J., Wistuba, I., Xiao, G., Minna, J. & Xie, Y., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalComment/debate

Development and Validation of a Pathology Image Analysis-based Predictive Model for Lung Adenocarcinoma Prognosis - A Multi-cohort Study

Luo, X., Yin, S., Yang, L., Fujimoto, J., Yang, Y., Moran, C., Kalhor, N., Weissferdt, A., Xie, Y., Gazdar, A., Minna, J., Wistuba, I. I., Mao, Y. & Xiao, G., Dec 1 2019, In : Scientific reports. 9, 1, 6886.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

Bansal, M., He, J., Peyton, M., Kustagi, M., Iyer, A., Comb, M., White, M. A., Minna, J. D. & Califano, A., Jan 1 2019, In : PLoS One. 14, 1, e0208646.

Research output: Contribution to journalArticle

From clinical specimens to human cancer preclinical models—a journey the NCI-cell line database—25 years later

Mulshine, J. L., Ujhazy, P., Antman, M., Burgess, C. M., Kuzmin, I., Bunn, P. A., Johnson, B. E., Roth, J. A., Pass, H. I., Ross, S. M., Aldige, C. R., Wistuba, I. I. & Minna, J. D., Jan 1 2019, (Accepted/In press) In : Journal of Cellular Biochemistry.

Research output: Contribution to journalArticle

Open Access

Inhibition of thioredoxin/thioredoxin reductase induces synthetic lethality in lung cancers with compromised glutathione homeostasis

Yan, X., Zhang, X., Wang, L., Zhang, R., Pu, X., Wu, S., Li, L., Tong, P., Wang, J., Meng, Q. H., Jensen, V. B., Girard, L., Minna, J. D., Roth, J. A., Swisher, S. G., Heymach, J. V. & Fang, B., Jan 1 2019, In : Cancer Research. 79, 1, p. 125-132 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

LCE: an open web portal to explore gene expression and clinical associations in lung cancer

Cai, L., Lin, S. Y., Girard, L., Zhou, Y., Yang, L., Ci, B., Zhou, Q., Luo, D., Yao, B., Tang, H., Allen, J., Huffman, K., Gazdar, A. F., Heymach, J., Wistuba, I., Xiao, G., Minna, J. D. & Xie, Y., Apr 4 2019, In : Oncogene. 38, 14, p. 2551-2564 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

LKB1 and KEAP1/NRF2 pathways cooperatively promote metabolic reprogramming with enhanced glutamine dependence inKRAS-mutant lung adenocarcinoma

Galan-Cobo, A., Sitthideatphaiboon, P., Qu, X., Poteete, A., Pisegna, M. A., Tong, P., Chen, P. H., Boroughs, L. K., Rodriguez, M. L. M., Zhang, W., Parlati, F., Wang, J., Gandhi, V., Skoulidis, F., DeBerardinis, R. J., Minna, J. D. & Heymach, J. V., Jan 1 2019, In : Cancer research. 79, 13, p. 3251-3267 17 p.

Research output: Contribution to journalArticle

12 Scopus citations

Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells

Chen, P. H., Cai, L., Huffman, K., Yang, C., Kim, J., Faubert, B., Boroughs, L., Ko, B., Sudderth, J., McMillan, E. A., Girard, L., Chen, D., Peyton, M., Shields, M. D., Yao, B., Shames, D. S., Kim, H. S., Timmons, B., Sekine, I., Britt, R. & 8 others, Weber, S., Byers, L. A., Heymach, J. V., Chen, J., White, M. A., Minna, J. D., Xiao, G. & DeBerardinis, R. J., Dec 5 2019, In : Molecular cell. 76, 5, p. 838-851.e5

Research output: Contribution to journalArticle

5 Scopus citations

Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

Rudin, C. M., Poirier, J. T., Byers, L. A., Dive, C., Dowlati, A., George, J., Heymach, J. V., Johnson, J. E., Lehman, J. M., MacPherson, D., Massion, P. P., Minna, J. D., Oliver, T. G., Quaranta, V., Sage, J., Thomas, R. K., Vakoc, C. R. & Gazdar, A. F., Jan 1 2019, In : Nature Reviews Cancer.

Research output: Contribution to journalArticle

30 Scopus citations

p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas

Hsieh, M. H., Choe, J. H., Gadhvi, J., Kim, Y. J., Arguez, M. A., Palmer, M., Gerold, H., Nowak, C., Do, H., Mazambani, S., Knighton, J. K., Cha, M., Goodwin, J., Kang, M. K., Jeong, J. Y., Lee, S. Y., Faubert, B., Xuan, Z., Abel, E. D., Scafoglio, C. & 11 others, Shackelford, D. B., Minna, J. D., Singh, P. K., Shulaev, V., Bleris, L., Hoyt, K., Kim, J., Inoue, M., DeBerardinis, R. J., Kim, T. H. & Kim, J. W., Aug 13 2019, In : Cell Reports. 28, 7, p. 1860-1878.e9

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Small cell lung cancers made from scratch

Gazdar, A. F. & Minna, J. D., Mar 1 2019, In : Journal of Experimental Medicine. 216, 3, p. 476-478 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells

Wang, X. D., Hu, R., Ding, Q., Savage, T. K., Huffman, K. E., Williams, N. S., Cobb, M. H., Minna, J. D., Johnson, J. E. & Yu, Y., Dec 1 2019, In : Nature communications. 10, 1, 3201.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Systematic analysis of gene expression in lung adenocarcinoma and squamous cell carcinoma with a case study of FAM83A and FAM83B

Cai, L., Luo, D., Yao, B., Yang, D. M., Lin, S., Girard, L., Deberardinis, R. J., Minna, J. D., Xie, Y. & Xiao, G., Jun 1 2019, In : Cancers. 11, 6, 886.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Unbiased peptoid combinatorial cell screen identifies plectin protein as a potential biomarker for lung cancer stem cells

Raymond, A. C., Gao, B., Girard, L., Minna, J. D. & Gomika Udugamasooriya, D., Dec 1 2019, In : Scientific reports. 9, 1, 14954.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Validation of the 12-gene predictive signature for adjuvant chemotherapy response in lung cancer

Xie, Y., Lu, W., Wang, S., Tang, X., Tang, H., Zhou, Y., Moran, C., Behrens, C., Roth, J. A., Zhou, Q., Johnson, D. H., Swisher, S. G., Heymach, J. V., Papadimitrakopoulou, V. A., Xiao, G., Minna, J. D. & Wistuba, I. I., Jan 1 2019, In : Clinical Cancer Research. 25, 1, p. 150-157 8 p.

Research output: Contribution to journalArticle

2018

A quantitative method for assessing smoke associated molecular damage in lung cancers

Song, K., Bi, J. H., Qiu, Z. W., Felizardo, R., Girard, L., Minna, J. D. & Gazdar, A. F., Jan 1 2018, In : Translational Lung Cancer Research. 7, 4, p. 439-449 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer

McMillan, E. A., Ryu, M. J., Diep, C. H., Mendiratta, S., Clemenceau, J. R., Vaden, R. M., Kim, J. H., Motoyaji, T., Covington, K. R., Peyton, M., Huffman, K., Wu, X., Girard, L., Sung, Y., Chen, P. H., Mallipeddi, P. L., Lee, J. Y., Hanson, J., Voruganti, S., Yu, Y. & 20 others, Park, S., Sudderth, J., DeSevo, C., Muzny, D. M., Doddapaneni, H. V., Gazdar, A., Gibbs, R. A., Hwang, T. H., Heymach, J. V., Wistuba, I., Coombes, K. R., Williams, N. S., Wheeler, D. A., MacMillan, J. B., Deberardinis, R. J., Roth, M. G., Posner, B. A., Minna, J. D., Kim, H. S. & White, M. A., May 3 2018, In : Cell. 173, 4, p. 864-878.e29

Research output: Contribution to journalArticle

20 Scopus citations

Concomitant targeting of the mTOR/MAPK pathways: Novel therapeutic strategy in subsets of RICTOR/KRAS-altered non-small cell lung cancer

Ruder, D., Papadimitrakopoulou, V., Shien, K., Behrens, C., Kalhor, N., Chen, H., Shen, L., Jack Lee, J., Hong, W. K., Tang, X., Girard, L., Minna, J. D., Diao, L., Wang, J., Mino, B., Villalobos, P., Rodriguez-Canales, J., Hanson, N. E., Sun, J., Miller, V. & 6 others, Greenbowe, J., Frampton, G., Herbst, R. S., Baladandayuthapani, V., Wistuba, I. I. & Izzo, J. G., Sep 1 2018, In : Oncotarget. 9, 74, p. 33995-34008 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Diagnosis and management of pulmonary toxicity associated with cancer immunotherapy

Rashdan, S., Minna, J. D. & Gerber, D. E., Jun 1 2018, In : The Lancet Respiratory Medicine. 6, 6, p. 472-478 7 p.

Research output: Contribution to journalComment/debate

10 Scopus citations

Different originating cells underlie intertumoral heterogeneity in lung neuroendocrine tumors

Pozo, K., Kelenis, D. P., Minna, J. D. & Johnson, J. E., Oct 1 2018, In : Cancer Discovery. 8, 10, p. 1216-1218 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

eIF2β, a subunit of translation-initiation factor EIF2, is a potential therapeutic target for non-small cell lung cancer

Tanaka, I., Sato, M., Kato, T., Goto, D., Kakumu, T., Miyazawa, A., Yogo, N., Hase, T., Morise, M., Sekido, Y., Girard, L., Minna, J. D., Byers, L. A., Heymach, J. V., Coombes, K. R., Kondo, M. & Hasegawa, Y., Jun 2018, In : Cancer Science. 109, 6, p. 1843-1852 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Estrogen receptor beta-mediated modulation of lung cancer cell proliferation by 27-hydroxycholesterol

Hiramitsu, S., Ishikawa, T., Lee, W. R., Khan, T., Crumbley, C., Khwaja, N., Zamanian, F., Asghari, A., Sen, M., Zhang, Y., Hawse, J. R., Minna, J. D. & Umetani, M., Aug 23 2018, In : Frontiers in Endocrinology. 9, AUG, 470.

Research output: Contribution to journalArticle

5 Scopus citations

Evaluating tumor-suppressor gene combinations news-and-views

Kim, J. & Minna, J. D., Apr 1 2018, In : Nature Genetics. 50, 4, p. 480-482 3 p.

Research output: Contribution to journalShort survey

HORMAD1 is a negative prognostic indicator in lung adenocarcinoma and specifies resistance to oxidative and genotoxic stress

Nichols, B. A., Oswald, N. W., McMillan, E. A., McGlynn, K., Yan, J., Kim, M. S., Saha, J., Mallipeddi, P. L., LaDuke, S. A., Villalobos, P. A., Rodriguez-Canales, J., Wistuba, I. I., Posner, B. A., Davis, A. J., Minna, J. D., MacMillan, J. B. & Whitehurst, A. W., Nov 1 2018, In : Cancer research. 78, 21, p. 6196-6208 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Identifying a missing lineage driver in a subset of lung neuroendocrine tumors

Pozo, K., Minna, J. D. & Johnson, J. E., Jul 1 2018, In : Genes and Development. 32, 13-14, p. 865-867 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers

Huang, F., Ni, M., Chalishazar, M. D., Huffman, K. E., Kim, J., Cai, L., Shi, X., Cai, F., Zacharias, L. G., Ireland, A. S., Li, K., Gu, W., Kaushik, A. K., Liu, X., Gazdar, A. F., Oliver, T. G., Minna, J. D., Hu, Z. & DeBerardinis, R. J., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

22 Scopus citations

Kub5-HeraRPRD1B Deficiency Promotes "BRCAness" and Vulnerability to PARP Inhibition in BRCA-proficient Breast Cancers

Motea, E. A., Fattah, F. J., Xiao, L., Girard, L., Rommel, A., Morales, J. C., Patidar, P., Zhou, Y., Porter, A., Xie, Y., Minna, J. D. & Boothman, D. A., Dec 15 2018, In : Clinical Cancer Research. 24, 24, p. 6459-6470 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer

Du, L., Zhao, Z., Suraokar, M., Shelton, S. S., Ma, X., Hsiao, T. H., Minna, J. D., Wistuba, I. & Pertsemlidis, A., Jul 1 2018, In : Oncotarget. 9, 51, p. 29601-29618 18 p.

Research output: Contribution to journalArticle

2 Scopus citations

Retraction notice to “Sun exposure related methylation in malignant and non-malignant skin lesions” [Cancer Letters 245/1-2 (2007) 112-120] (S0304383506000036) (10.1016/j.canlet.2005.12.042))

Sathyanarayana, U. G., Moore, A. Y., Li, L., Padar, A., Majmudar, K., Stastny, V., Makarla, P., Suzuki, M., Minna, J. D., Feng, Z. & Gazdar, A. F., Sep 28 2018, In : Cancer Letters. 432, 1 p.

Research output: Contribution to journalComment/debate

Silencing the snail-dependent RNA splice regulator ESRP1 drives malignant transformation of human pulmonary epithelial cells

Walser, T. C., Jing, Z., Tran, L. M., Lin, Y. Q., Yakobian, N., Wang, G., Krysan, K., Zhu, L. X., Sharma, S., Lee, M. H., Belperio, J. A., Ooi, A. T., Gomperts, B. N., Shay, J. W., Larsen, J. E., Minna, J. D., Hong, L. S., Fishbein, M. C. & Dubinett, S. M., Apr 15 2018, In : Cancer Research. 78, 8, p. 1986-1999 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

Small cell lung cancer tumors and preclinical models display heterogeneity of neuroendocrine phenotypes

Zhang, W., Girard, L., Zhang, Y. A., Haruki, T., Papari-Zareei, M., Stastny, V., Ghayee, H. K., Pacak, K., Oliver, T. G., Minna, J. D. & Gazdar, A. F., Feb 1 2018, In : Translational Lung Cancer Research. 7, 1, p. 32-49 18 p.

Research output: Contribution to journalArticle

19 Scopus citations

Telomerase-Mediated Strategy for Overcoming Non–Small Cell Lung Cancer Targeted Therapy and Chemotherapy Resistance

Mender, I., LaRanger, R., Luitel, K., Peyton, M., Girard, L., Lai, T. P., Batten, K., Cornelius, C., Dalvi, M. P., Ramirez, M., Du, W., Wu, L. F., Altschuler, S. J., Brekken, R., Martinez, E. D., Minna, J. D., Wright, W. E. & Shay, J. W., Aug 1 2018, In : Neoplasia (United States). 20, 8, p. 826-837 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

The Epithelial Sodium Channel (αENaC) Is a Downstream Therapeutic Target of ASCL1 in Pulmonary Neuroendocrine Tumors

He, M., Liu, S., Gallolu Kankanamalage, S., Borromeo, M. D., Girard, L., Gazdar, A. F., Minna, J. D., Johnson, J. E. & Cobb, M. H., Apr 1 2018, In : Translational Oncology. 11, 2, p. 292-299 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

The impact of smoking and tp53 mutations in lung adenocarcinoma patients with targetable mutations—the lung cancer mutation consortium (LCMC2)

Aisner, D. L., Sholl, L. M., Berry, L. D., Rossi, M. R., Chen, H., Fujimoto, J., Moreira, A. L., Ramalingam, S. S., Villaruz, L. C., Otterson, G. A., Haura, E., Politi, K., Glisson, B., Cetnar, J., Garon, E. B., Schiller, J., Waqar, S. N., Sequist, L. V., Brahmer, J., Shyr, Y. & 7 others, Kugler, K., Wistuba, I. I., Johnson, B. E., Minna, J. D., Kris, M. G., Bunn, P. A. & Kwiatkowski, D. J., Mar 1 2018, In : Clinical Cancer Research. 24, 5, p. 1038-1047 10 p.

Research output: Contribution to journalArticle

58 Scopus citations

The molecular biology of lung cancer

Larsen, J. E. & Minna, J. D., Nov 16 2018, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 607-618 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer

Gong, K., Guo, G., Gerber, D. E., Gao, B., Peyton, M., Huang, C., Minna, J. D., Hatanpaa, K. J., Kernstine, K., Cai, L., Xie, Y., Zhu, H., Fattah, F. J., Zhang, S., Takahashi, M., Mukherjee, B., Burma, S., Dowell, J., Dao, K., Papadimitrakopoulou, V. A. & 4 others, Olivas, V., Bivona, T. G., Zhao, D. & Habib, A. A., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2500-2518 19 p.

Research output: Contribution to journalArticle

14 Scopus citations

Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism

Updegraff, B. L., Zhou, X., Guo, Y., Padanad, M. S., Chen, P. H., Yang, C., Sudderth, J., Rodriguez-Tirado, C., Girard, L., Minna, J. D., Mishra, P., DeBerardinis, R. J. & O'Donnell-Mendell, K. A., Jan 1 2018, (Accepted/In press) In : Cell Reports.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

Li, J., Zhao, W., Akbani, R., Liu, W., Ju, Z., Ling, S., Vellano, C. P., Roebuck, P., Yu, Q., Eterovic, A. K., Byers, L. A., Davies, M. A., Deng, W., Gopal, Y. N. V., Chen, G., von Euw, E. M., Slamon, D., Conklin, D., Heymach, J. V., Gazdar, A. F. & 5 others, Minna, J. D., Myers, J. N., Lu, Y., Mills, G. B. & Liang, H., Feb 13 2017, In : Cancer Cell. 31, 2, p. 225-239 15 p.

Research output: Contribution to journalArticle

68 Scopus citations