Research output per year
Research output per year
- 1 - 50 out of 993 results
Search results
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2024
A telomere-targeting drug depletes cancer initiating cells and promotes anti-tumor immunity in small cell lung cancer
Eglenen-Polat, B., Kowash, R. R., Huang, H. C., Siteni, S., Zhu, M., Chen, K., Bender, M. E., Mender, I., Stastny, V., Drapkin, B. J., Raj, P., Minna, J. D., Xu, L., Shay, J. W. & Akbay, E. A., Dec 2024, In: Nature communications. 15, 1, 672.Research output: Contribution to journal › Article › peer-review
Open Access -
Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors
Kim, C., Wang, X. D., Liu, Z., Hao, J., Wang, S., Li, P., Zi, Z., Ding, Q., Jang, S., Kim, J., Luo, Y., Huffman, K. E., Choudhuri, S. P., del Rio, S., Cai, L., Liang, H., Drapkin, B. J., Minna, J. D. & Yu, Y., Jan 2024, In: Science Advances. 10, 3Research output: Contribution to journal › Article › peer-review
Open Access -
Proteomics: A new dimension to decode small cell lung cancer
Chen, H., Drapkin, B. J. & Minna, J. D., Jan 4 2024, In: Cell. 187, 1, p. 14-16 3 p.Research output: Contribution to journal › Comment/debate › peer-review
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The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β-catenin signaling in lung cancer
Sunaga, N., Kaira, K., Shimizu, K., Tanaka, I., Miura, Y., Nakazawa, S., Ohtaki, Y., Kawabata-Iwakawa, R., Sato, M., Girard, L., Minna, J. D. & Hisada, T., Jan 2024, In: Thoracic Cancer. 15, 2, p. 131-141 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
A comparative study of neuroendocrine heterogeneity in small cell lung cancer and neuroblastoma
Cai, L., De Berardinis, R. J., Xie, Y., Minna, J. D. & Xiao, G., Aug 1 2023, In: Molecular Cancer Research. 21, 8, p. 795-807 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance
Nilsson, M. B., Yang, Y., Heeke, S., Patel, S. A., Poteete, A., Udagawa, H., Elamin, Y. Y., Moran, C. A., Kashima, Y., Arumugam, T., Yu, X., Ren, X., Diao, L., Shen, L., Wang, Q., Zhang, M., Robichaux, J. P., Shi, C., Pfeil, A. N., Tran, H., & 7 others, Feb 13 2023, In: Cancer Cell. 41, 2, p. 340-355.e6Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Deep learning of cell spatial organizations identifies clinically relevant insights in tissue images
Wang, S., Rong, R., Zhou, Q., Yang, D. M., Zhang, X., Zhan, X., Bishop, J., Chi, Z., Wilhelm, C. J., Zhang, S., Pickering, C. R., Kris, M. G., Minna, J., Xie, Y. & Xiao, G., Dec 2023, In: Nature communications. 14, 1, 7872.Research output: Contribution to journal › Article › peer-review
Open Access -
Dissecting molecular, pathological, and clinical features associated with tumor neural/neuroendocrine heterogeneity
Cai, L., DeBerardinis, R. J., Xiao, G., Minna, J. D. & Xie, Y., Jun 16 2023, In: iScience. 26, 6, 106983.Research output: Contribution to journal › Article › peer-review
Open Access -
Features of tumor-microenvironment images predict targeted therapy survival benefit in patients with EGFR-mutant lung cancer
Wang, S., Rong, R., Yang, D. M., Fujimoto, J., Bishop, J. A., Yan, S., Cai, L., Behrens, C., Berry, L. D., Wilhelm, C., Aisner, D., Sholl, L., Johnson, B. E., Kwiatkowski, D. J., Wistuba, I. I., Bunn, P. A., Minna, J., Xiao, G., Kris, M. G. & Xie, Y., Jan 17 2023, In: Journal of Clinical Investigation. 133, 2, e160330.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers
Huffman, K. E., Li, L. S., Carstens, R., Park, H., Girard, L., Avila, K., Wei, S., Kollipara, R., Timmons, B., Sudderth, J., Bendris, N., Kim, J., Villalobos, P., Fujimoto, J., Schmid, S., Deberardinis, R. J., Wistuba, I., Heymach, J., Kittler, R., Akbay, E. A., & 6 others, 2023, In: Frontiers in Oncology. 13, 1025443.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
IL-1β mediates the induction of immune checkpoint regulators IDO1 and PD-L1 in lung adenocarcinoma cells
Nawas, A. F., Solmonson, A., Gao, B., DeBerardinis, R. J., Minna, J. D., Conacci-Sorrell, M. & Mendelson, C. R., Dec 2023, In: Cell Communication and Signaling. 21, 1, 331.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer
Rodilla, A. M., Valanparambil, R. M., Mack, P. C., Hsu, C. Y., Cagan, J., Tavolacci, S. C., Carreño, J. M., Brody, R., Moore, A., King, J. C., Gomez, J. E., Rohs, N., Rolfo, C., Bunn, P. A., Gerber, D. E., Minna, J. D., Krammer, F., Ramalingam, S. S., García-Sastre, A., Shyr, Y., & 2 others, Nov 13 2023, In: Cancer Cell. 41, 11, p. 1838-1840 3 p.Research output: Contribution to journal › Letter › peer-review
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Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden
Zhu, M., Kim, J., Deng, Q., Ricciuti, B., Alessi, J. V., Eglenen-Polat, B., Bender, M. E., Huang, H. C., Kowash, R. R., Cuevas, I., Bennett, Z. T., Gao, J., Minna, J. D., Castrillon, D. H., Awad, M. M., Xu, L. & Akbay, E. A., Oct 9 2023, In: Cancer Cell. 41, 10, p. 1731-1748.e8Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma
Qian, Y., Galan-Cobo, A., Guijarro, I., Dang, M., Molkentine, D., Poteete, A., Zhang, F., Wang, Q., Wang, J., Parra, E., Panda, A., Fang, J., Skoulidis, F., Wistuba, I. I., Verma, S., Merghoub, T., Wolchok, J. D., Wong, K. K., DeBerardinis, R. J., Minna, J. D., & 6 others, Jul 10 2023, In: Cancer Cell. 41, 7, p. 1363-1380.e7Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Moving toward precision medicine with lung cancer organoids
Kim, J. & Minna, J. D., Feb 21 2023, In: Cell Reports Medicine. 4, 2, 100952.Research output: Contribution to journal › Comment/debate › peer-review
Open Access2 Scopus citations -
Silencing of GRHL2 induces epithelial-to-mesenchymal transition in lung cancer cell lines with different effects on proliferation and clonogenic growth
Kawabe, N., Matsuoka, K., Komeda, K., Muraki, N., Takaba, M., Togami, Y., Ito, Y., Yamada, M., Sunaga, N., Girard, L., Minna, J. D., Cai, L., Xie, Y., Tanaka, I., Morise, M. & Sato, M., Oct 2023, In: Oncology Letters. 26, 3, 391.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Single-cell transcriptomic analysis uncovers intratumoral heterogeneity and drug-tolerant persister in ALK-rearranged lung adenocarcinoma
Kwok, H. H., Li, H., Yang, J., Deng, J., Lee, N. C. M., Au, T. W. K., Sit, A. K. Y., Hsin, M. K. Y., Ma, S. K. Y., Cheung, L. W. T., Girard, L., Fujimoto, J., Wistuba, I. I., Gao, B., Minna, J. D. & Lam, D. C. L., Aug 2023, In: Cancer Communications. 43, 8, p. 951-955 5 p.Research output: Contribution to journal › Letter › peer-review
Open Access1 Scopus citations -
Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer
Malchers, F., Nogova, L., van Attekum, M. H. A., Maas, L., Brägelmann, J., Bartenhagen, C., Girard, L., Bosco, G., Dahmen, I., Michels, S., Weeden, C. E., Scheel, A. H., Meder, L., Golfmann, K., Schuldt, P., Siemanowski, J., Rehker, J., Merkelbach-Bruse, S., Menon, R., Gautschi, O., & 14 others, Nov 1 2023, In: Journal of Clinical Investigation. 133, 21, e174171.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Systematic investigation of mitochondrial transfer between cancer cells and T cells at single-cell resolution
Zhang, H., Yu, X., Ye, J., Li, H., Hu, J., Tan, Y., Fang, Y., Akbay, E., Yu, F., Weng, C., Sankaran, V. G., Bachoo, R. M., Maher, E., Minna, J., Zhang, A. & Li, B., Oct 9 2023, In: Cancer Cell. 41, 10, p. 1788-1802.e10Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Tumor loss-of-function mutations in STK11/LKB1 induce cachexia
Iyengar, P., Gandhi, A. Y., Granados, J., Guo, T., Gupta, A., Yu, J., Llano, E. M., Zhang, F., Gao, A., Kandathil, A., Williams, D., Gao, B., Girard, L., Malladi, V. S., Shelton, J. M., Evers, B. M., Hannan, R., Ahn, C., Minna, J. D. & Infante, R. E., 2023, In: JCI Insight. 8, 8, e165419.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2022
A Method for Orthotopic Transplantation of Lung Cancer in Mice
Wilson, A. N., Chen, B., Liu, X., Kurie, J. M. & Kim, J., 2022, Methods in Molecular Biology. Humana Press Inc., p. 231-242 12 p. (Methods in Molecular Biology; vol. 2374).Research output: Chapter in Book/Report/Conference proceeding › Chapter
3 Scopus citations -
AP-1 leads the way in lung cancer transformation
Kim, J. & Minna, J. D., Feb 7 2022, In: Developmental cell. 57, 3, p. 292-294 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access3 Scopus citations -
A Pan-Cancer Assessment of RB1/TP53 Co-Mutations
Cai, L., DeBerardinis, R. J., Xiao, G., Minna, J. D. & Xie, Y., Sep 2022, In: Cancers. 14, 17, 4199.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Author Correction: Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment (Nature Communications, (2021), 12, 1, (5086), 10.1038/s41467-021-25177-3)
The NCI PDXNet Consortium, Dec 2022, In: Nature communications. 13, 1, 294.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
Author Correction: Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer (Nature Communications, (2022), 13, 1, (4327), 10.1038/s41467-022-31963-4)
Bartolacci, C., Andreani, C., Vale, G., Berto, S., Melegari, M., Crouch, A. C., Baluya, D. L., Kemble, G., Hodges, K., Starrett, J., Politi, K., Starnes, S. L., Lorenzini, D., Raso, M. G., Solis Soto, L. M., Behrens, C., Kadara, H., Gao, B., Wistuba, I. I., Minna, J. D., & 2 others, Dec 2022, In: Nature communications. 13, 1, 4640.Research output: Contribution to journal › Comment/debate › peer-review
Open Access3 Scopus citations -
AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
Li, H., Liu, Z., Liu, L., Zhang, H., Han, C., Girard, L., Park, H., Zhang, A., Dong, C., Ye, J., Rayford, A., Peyton, M., Li, X., Avila, K., Cao, X., Hu, S., Alam, M. M., Akbay, E. A., Solis, L. M., Behrens, C., & 13 others, Mar 15 2022, In: Cell Reports Medicine. 3, 3, 100554.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
Canonical Hedgehog Pathway and Noncanonical GLI Transcription Factor Activation in Cancer
Suchors, C. & Kim, J., Aug 2022, In: Cells. 11, 16, 2523.Research output: Contribution to journal › Review article › peer-review
Open Access9 Scopus citations -
Cellular senescence and lung cancer prognosis
Asaithamby, A., Shay, J. W. & Minna, J. D., Oct 2022, In: Translational Lung Cancer Research. 11, 10, p. 1982-1987 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
Circulating mitochondrial DNA as a biomarker for lung cancer screening
von Itzstein, M. S., Gerber, D. E. & Minna, J. D., Aug 2022, In: Translational Lung Cancer Research. 11, 8, p. 1522-1525 4 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Enhanced Vulnerability of LKB1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado
Galan-Cobo, A., Stellrecht, C. M., Yilmaz, E., Yang, C., Qian, Y., Qu, X., Akhter, I., Ayres, M. L., Fan, Y., Tong, P., Diao, L., Ding, J., Giri, U., Gudikote, J., Nilsson, M., Wierda, W. G., Wang, J., Skoulidis, F., Minna, J. D., Gandhi, V., & 1 others, Feb 2022, In: Molecular Cancer Research. 20, 2, p. 280-292 13 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Establishment of reference standards for multifaceted mosaic variant analysis
Ha, Y. J., Oh, M. J., Kim, J., Kim, J., Kang, S., Minna, J. D., Kim, H. S. & Kim, S., Dec 2022, In: Scientific Data. 9, 1, 35.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
High-throughput functional evaluation of human cancer-associated mutations using base editors
Kim, Y., Lee, S., Cho, S., Park, J., Chae, D., Park, T., Minna, J. D. & Kim, H. H., Jun 2022, In: Nature biotechnology. 40, 6, p. 874-884 11 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Integrative epigenomic analyses of small cell lung cancer cells demonstrates the clinical translational relevance of gene body methylation
Pongor, L. S., Tlemsani, C., Elloumi, F., Arakawa, Y., Jo, U., Gross, J. M., Mosavarpour, S., Varma, S., Kollipara, R. K., Roper, N., Teicher, B. A., Aladjem, M. I., Reinhold, W., Thomas, A., Minna, J. D., Johnson, J. E. & Pommier, Y., Nov 18 2022, In: iScience. 25, 11, 105338.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Longitudinal Analyses of COVID-19 Vaccination in Patients with Lung Cancer: Antibody Responses and Variant-Specific Neutralization
Mack, P. C., Hirsch, F. R., Bunn, P. A. & Minna, J. D., Nov 20 2022, In: Journal of Clinical Oncology. 40, 33, p. 3787-3789 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Longitudinal COVID-19-vaccination-induced antibody responses and Omicron neutralization in patients with lung cancer
PARIS/PSP study group, Jun 13 2022, In: Cancer Cell. 40, 6, p. 575-577 3 p.Research output: Contribution to journal › Letter › peer-review
Open Access10 Scopus citations -
Lung Cancer and Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Identifying Important Knowledge Gaps for Investigation
Rolfo, C., Meshulami, N., Russo, A., Krammer, F., García-Sastre, A., Mack, P. C., Gomez, J. E., Bhardwaj, N., Benyounes, A., Sirera, R., Moore, A., Rohs, N., Henschke, C. I., Yankelevitz, D., King, J., Shyr, Y., Bunn, P. A., Minna, J. D. & Hirsch, F. R., Feb 2022, In: Journal of Thoracic Oncology. 17, 2, p. 214-227 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access24 Scopus citations -
Lung Cancer Cell of Origin: Controversy and Clinical Translational Implications
Osborne, J. K. & Minna, J. D., Mar 15 2022, In: Cancer research. 82, 6, p. 972-973 2 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Lung Cancer Computational Biology and Resources
Cai, L., Xiao, G., Gerber, D., Minna, J. D. & Xie, Y., Feb 2022, In: Cold Spring Harbor Perspectives in Biology. 12, 2, a038273.Research output: Contribution to journal › Article › peer-review
Open Access -
Rare solid and cystic presentation of hemangiopericytoma/ solitary fibrous tumor: A case report
Hayenga, H. N., Cai, C., Fetzer, D., White, S., Kuban, J., Wardak, Z., Benjamin, R. S., Pan, E., Strauss, J., Gao, B., Minna, J., Martin-Broto, J. & Hinshaw, J. L., Jun 2022, In: Current Problems in Cancer: Case Reports. 6, 100149.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Resistance to mutant KRASV12-induced senescence in an hTERT/Cdk4-immortalized normal human bronchial epithelial cell line
Muraki, N., Yamada, M., Doki, H., Nakai, R., Komeda, K., Goto, D., Kawabe, N., Matsuoka, K., Matsushima, M., Kawabe, T., Tanaka, I., Morise, M., Shay, J. W., Minna, J. D. & Sato, M., May 1 2022, In: Experimental Cell Research. 414, 1, 113053.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
Han, J. H., Kim, Y. K., Kim, H., Lee, J., Oh, M. J., Kim, S. B., Kim, M., Kim, K. H., Yoon, H. J., Lee, M. S., Minna, J. D., White, M. A. & Kim, H. S., Aug 2022, In: Cancer Communications. 42, 8, p. 716-749 34 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer
Bartolacci, C., Andreani, C., Vale, G., Berto, S., Melegari, M., Crouch, A. C., Baluya, D. L., Kemble, G., Hodges, K., Starrett, J., Politi, K., Starnes, S. L., Lorenzini, D., Raso, M. G., Solis Soto, L. M., Behrens, C., Kadara, H., Gao, B., Wistuba, I. I., Minna, J. D., & 2 others, Dec 2022, In: Nature communications. 13, 1, 4327.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
Tumor Cells Modulate Macrophage Phenotype in a Novel In Vitro Co-Culture Model of the NSCLC Tumor Microenvironment
Park, J. V., Chandra, R., Cai, L., Ganguly, D., Li, H., Toombs, J. E., Girard, L., Brekken, R. A. & Minna, J. D., Oct 2022, In: Journal of Thoracic Oncology. 17, 10, p. 1178-1191 14 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Unbiased peptoid cell screen identifies a peptoid targeting newly appeared cell surface vimentin on tumor transformed early lung cancer cells
Shukla, S. P., Zhang, H., Fang, B., Minna, J. D. & Gomika Udugamasooriya, D., Mar 15 2022, In: Bioorganic and Medicinal Chemistry. 58, 116673.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2021
A call to action: Dismantling racial injustices in preclinical research and clinical care of black patients living with small cell lung cancer
Thomas, P. L., Madubata, C. J., Aldrich, M. C., Lee, M. M., Owonikoko, T. K., Minna, J. D., Rudin, C. M., Sage, J. & Lovly, C. M., Feb 2021, In: Cancer discovery. 11, 2, p. 240-244 5 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Altered Regulation of HIF-1α in Naive- and Drug-Resistant EGFR-Mutant NSCLC: Implications for a Vascular Endothelial Growth Factor-Dependent Phenotype
Nilsson, M. B., Robichaux, J., Herynk, M. H., Cascone, T., Le, X., Elamin, Y., Patel, S., Zhang, F., Xu, L., Hu, L., Diao, L., Shen, L., He, J., Yu, X., Nikolinakos, P., Saintigny, P., Fang, B., Girard, L., Wang, J., Minna, J. D., & 2 others, Mar 2021, In: Journal of Thoracic Oncology. 16, 3, p. 439-451 13 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
A rational targeted therapy for platinum-resistant small-cell lung cancer
Drapkin, B. J. & Minna, J. D., Apr 12 2021, In: Cancer Cell. 39, 4, p. 453-456 4 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
ASCL1, NKX2-1, and PROX1 co-regulate subtype-specific genes in small-cell lung cancer
Pozo, K., Kollipara, R. K., Kelenis, D. P., Rodarte, K. E., Ullrich, M. S., Zhang, X., Minna, J. D. & Johnson, J. E., Sep 24 2021, In: iScience. 24, 9, 102953.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Assessing consistency across functional screening datasets in cancer cells
Cai, L., Liu, H., Minna, J. D., Deberardinis, R. J., Xiao, G. & Xie, Y., Dec 1 2021, In: Bioinformatics. 37, 23, p. 4540-4547 8 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts (Nature Genetics, (2021), 53, 1, (86-99), 10.1038/s41588-020-00750-6)
PDXNET consortium & EurOPDX consortium, May 2021, In: Nature genetics. 53, 5, p. 761 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access4 Scopus citations