The Nancy B. and Jake L. Hamon Center for Therapeutic Oncology Research

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2017

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & Deberardinis, R. J., Jun 1 2017, In : Nature. 546, 7656, p. 168-172 5 p.

Research output: Contribution to journalArticle

71 Scopus citations

Genetic variations in cancer-related significantly mutated genes and lung cancer susceptibility

Zhang, Y., Zhang, L., Li, R., Chang, D. W., Ye, Y., Minna, J. D., Roth, J. A., Han, B. & Wu, X., Jul 1 2017, In : Annals of oncology : official journal of the European Society for Medical Oncology. 28, 7, p. 1625-1630 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of a human airway epithelial cell subpopulation with altered biophysical, molecular, and metastatic properties

Pagano, P. C., Tran, L. M., Bendris, N., O'Byrne, S., Tse, H. T., Sharma, S., Hoech, J. W., Park, S. J., Liclican, E. L., Jing, Z., Li, R., Krysan, K., Paul, M. K., Fontebasso, Y., Larsen, J. E., Hakimi, S., Seki, A., Fishbein, M. C., Gimzewski, J. K., Di Carlo, D. & 3 others, Minna, J. D., Walser, T. C. & Dubinett, S. M., Sep 1 2017, In : Cancer Prevention Research. 10, 9, p. 514-524 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Identification of proteasomal catalytic subunit PSMA6 as a therapeutic target for lung cancer

Kakumu, T., Sato, M., Goto, D., Kato, T., Yogo, N., Hase, T., Morise, M., Fukui, T., Yokoi, K., Sekido, Y., Girard, L., Minna, J. D., Byers, L. A., Heymach, J. V., Coombes, K. R., Kondo, M. & Hasegawa, Y., Apr 2017, In : Cancer Science. 108, 4, p. 732-743 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

JAK1/STAT3 activation through a proinflammatory cytokine pathway leads to resistance to molecularly targeted therapy in non–small cell lung cancer

Shien, K., Papadimitrakopoulou, V. A., Ruder, D., Behrens, C., Shen, L., Kalhor, N., Song, J., Lee, J. J., Wang, J., Tang, X., Herbst, R. S., Toyooka, S., Girard, L., Minna, J. D., Kurie, J. M., Wistuba, I. I. & Izzo, J. G., Oct 2017, In : Molecular Cancer Therapeutics. 16, 10, p. 2234-2245 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Non-malignant respiratory epithelial cells preferentially proliferate from resected non-small cell lung cancer specimens cultured under conditionally reprogrammed conditions

Gao, B., Huang, C., Kernstine, K., Pelekanou, V., Kluger, Y., Jiang, T., Peters-Hall, J. R., Coquelin, M., Girard, L., Zhang, W., Huffman, K., Oliver, D., Kinose, F., Haura, E., Teer, J. K., Rix, U., Le, A. T., Aisner, D. L., Varella-Garcia, M., Doebele, R. C. & 10 others, Covington, K. R., Hampton, O. A., Doddapaneni, H. V., Jayaseelan, J. C., Hu, J., Wheeler, D. A., Shay, J. W., Rimm, D. L., Gazdar, A. & Minna, J. D., 2017, In : Oncotarget. 8, 7, p. 11114-11126 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Proportion of Never-Smoker Non-Small Cell Lung Cancer Patients at Three Diverse Institutions

Pelosof, L., Ahn, C., Gao, A., Horn, L., Madrigales, A., Cox, J., McGavic, D., Minna, J. D., Gazdar, A. F. & Schiller, J., Jul 1 2017, In : Journal of the National Cancer Institute. 109, 7, djw295.

Research output: Contribution to journalArticle

35 Scopus citations

PROTOCADHERIN 7 acts through SET and PP2A to potentiate MAPK signaling by EGFR and KRAS during lung tumorigenesis

Zhou, X., Updegraff, B. L., Guo, Y., Peyton, M., Girard, L., Larsen, J. E., Xie, X-J., Zhou, Y., Hwang, T. H., Xie, Y., Rodriguez-Canales, J., Villalobos, P., Behrens, C., Wistuba, I. I., Minna, J. D. & O'Donnell-Mendell, K. A., Jan 1 2017, In : Cancer research. 77, 1, p. 187-197 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Quantitative Proteomic Analysis of Optimal Cutting Temperature (OCT) Embedded Core-Needle Biopsy of Lung Cancer

Zhao, X., Huffman, K. E., Fujimoto, J., Canales, J. R., Girard, L., Nie, G., Heymach, J. V., Wistuba, I. I., Minna, J. D. & Yu, Y., Oct 1 2017, In : Journal of the American Society for Mass Spectrometry. 28, 10, p. 2078-2089 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers

Tagal, V., Wei, S., Zhang, W., Brekken, R. A., Posner, B. A., Peyton, M., Girard, L., Hwang, T., Wheeler, D. A., Minna, J. D., White, M. A., Gazdar, A. F. & Roth, M. G., Jan 19 2017, In : Nature Communications. 8, 14098.

Research output: Contribution to journalArticle

30 Scopus citations

Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors

Dalvi, M. P., Wang, L., Zhong, R., Kollipara, R. K., Park, H., Bayo, J., Yenerall, P., Zhou, Y., Timmons, B. C., Rodriguez-Canales, J., Behrens, C., Mino, B., Villalobos, P., Parra, E. R., Suraokar, M., Pataer, A., Swisher, S. G., Kalhor, N., Bhanu, N. V., Garcia, B. A. & 9 others, Heymach, J. V., Coombes, K., Xie, Y., Girard, L., Gazdar, A. F., Kittler, R., Wistuba, I. I., Minna, J. D. & Martinez, E. D., May 23 2017, In : Cell Reports. 19, 8, p. 1669-1684 16 p.

Research output: Contribution to journalArticle

35 Scopus citations

The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition

Goodwin, J., Neugent, M. L., Lee, S. Y., Choe, J. H., Choi, H., Enkins, D. M. R. J., Ruthenborg, R. J., Robinson, M. W., Jeong, J. Y., Wake, M., Abe, H., Takeda, N., Endo, H., Inoue, M., Xuan, Z., Yoo, H., Chen, M., Ahn, J. M., Minna, J. D., Helke, K. L. & 3 others, Singh, P. K., Shackelford, D. B. & Kim, J. W., May 26 2017, In : Nature communications. 8, 15503.

Research output: Contribution to journalArticle

55 Scopus citations
2016

An expression signature as an aid to the histologic classification of non-small cell lung cancer

Girard, L., Rodriguez-Canales, J., Behrens, C., Thompson, D. M., Botros, I. W., Tang, H., Xie, Y., Rekhtman, N., Travis, W. D., Wistuba, I. I., Minna, J. D. & Gazdar, A. F., Oct 1 2016, In : Clinical Cancer Research. 22, 19, p. 4880-4889 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs

Borromeo, M. D., Savage, T. K., Kollipara, R. K., He, M., Augustyn, A., Osborne, J. K., Girard, L., Minna, J. D., Gazdar, A. F., Cobb, M. H. & Johnson, J. E., Aug 2 2016, In : Cell Reports. 16, 5, p. 1259-1272 14 p.

Research output: Contribution to journalArticle

97 Scopus citations

A statistical method for detecting differentially expressed SNVs based on next-generation RNA-seq data

Fu, R., Wang, P., Ma, W., Taguchi, A., Wong, C. H., Zhang, Q., Gazdar, A., Hanash, S. M., Zhou, Q., Zhong, H. & Feng, Z., 2016, (Accepted/In press) In : Biometrics.

Research output: Contribution to journalArticle

Auranofin-mediated inhibition of PI3K/AKT/mTOR axis and anticancer activity in non-small cell lung cancer cells

Li, H., Hu, J., Wu, S., Wang, L., Cao, X., Zhang, X., Dai, B., Cao, M., Shao, R., Zhang, R., Majidi, M., Ji, L., Heymach, J. V., Wang, M., Pan, S., Minna, J., Mehran, R. J., Swisher, S. G., Roth, J. A. & Fang, B., 2016, In : Oncotarget. 7, 3, p. 3548-3558 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Cancer-specific production of n-acetylaspartate via nat8l overexpression in non-small cell lung cancer and its potential as a circulating biomarker

Lou, T. F., Sethuraman, D., Dospoy, P., Srivastva, P., Kim, H. S., Kim, J., Ma, X., Chen, P. H., Huffman, K. E., Frink, R. E., Larsen, J. E., Lewis, C., Um, S. W., Kim, D. H., Ahn, J. M., DeBerardinis, R. J., White, M. A., Minna, J. D. & Yoo, H., Jan 1 2016, In : Cancer Prevention Research. 9, 1, p. 43-52 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Computational discovery of pathway-level genetic vulnerabilities in non-small-cell lung cancer

Young, J. H., Peyton, M., Seok Kim, H., Mcmillan, E., Minna, J. D., White, M. A. & Marcotte, E. M., May 1 2016, In : Bioinformatics. 32, 9, p. 1373-1379 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Developing EZH2-targeted therapy for lung cancer

Frankel, A. E., Liu, X. & Minna, J. D., Sep 2016, In : Cancer discovery. 6, 9, p. 949-952 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Epithelial-mesenchymal transition predicts polo-like kinase 1 inhibitor-mediated apoptosis in non-small cell lung cancer

Ferrarotto, R., Goonatilake, R., Yoo, S. Y., Tong, P., Giri, U., Peng, S., Minna, J., Girard, L., Wang, Y., Wang, L., Li, L., Diao, L., Peng, D. H., Gibbons, D. L., Glisson, B. S., Heymach, J. V., Wang, J., Byers, L. A. & Johnson, F. M., Apr 1 2016, In : Clinical Cancer Research. 22, 7, p. 1674-1686 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis

Padanad, M. S., Konstantinidou, G., Venkateswaran, N., Melegari, M., Rindhe, S., Mitsche, M., Yang, C., Batten, K., Huffman, K. E., Liu, J., Tang, X., Rodriguez-Canales, J., Kalhor, N., Shay, J. W., Minna, J. D., McDonald, J., Wistuba, I. I., DeBerardinis, R. J. & Scaglioni, P. P., Aug 9 2016, In : Cell Reports. 16, 6, p. 1614-1628 15 p.

Research output: Contribution to journalArticle

52 Scopus citations

Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells

Yan, Y., Liu, L., Xiong, H., Miller, J. B., Zhou, K., Kos, P., Huffman, K. E., Elkassih, S., Norman, J. W., Carstens, R., Kim, J., Minna, J. D. & Siegwart, D. J., Sep 27 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 39, p. E5702-E5710

Research output: Contribution to journalArticle

39 Scopus citations

Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer

Kim, D. W., Wu, N., Kim, Y. C., Cheng, P. F., Basom, R., Kim, D., Dunn, C. T., Lee, A. Y., Kim, K., Lee, C. S., Singh, A., Gazdar, A. F., Harris, C. R., Eisenman, R. N., Park, K. S. & MacPherson, D., Jun 1 2016, In : Genes and Development. 30, 11, p. 1289-1299 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Identification of gene expression differences between lymphangiogenic and non-lymphangiogenic non-small cell lung cancer cell lines

Regan, E., Sibley, R. C., Cenik, B. K., Silva, A., Girard, L., Minna, J. D. & Dellinger, M. T., Mar 1 2016, In : PLoS One. 11, 3, e150963.

Research output: Contribution to journalArticle

7 Scopus citations

Identification of lipid-phosphatidylserine (PS) as the target of unbiasedly selected cancer specific peptide-peptoid hybrid PPS1

Desai, T. J., Toombs, J. E., Minna, J. D., Brekken, R. A. & Udugamasooriya, D. G., May 24 2016, In : Oncotarget. 7, 21, p. 30678-30690 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Inhibiting the Jumonji family: A potential new clinical approach to targeting aberrant epigenetic mechanisms

Martinez, E. D. & Gazdar, A. F., Mar 1 2016, In : Epigenomics. 8, 3, p. 313-316 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

ITPKA gene body methylation regulates gene expression and serves as an early diagnostic marker in lung and other cancers

Wang, Y. W., Ma, X., Zhang, Y. A., Wang, M. J., Yatabe, Y., Lam, S., Girard, L., Chen, J. Y. & Gazdar, A. F., Jan 1 2016, In : Journal of Thoracic Oncology. 11, 9, p. 1469-1481 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors

Huang, X., Motea, E. A., Moore, Z. R., Yao, J., Dong, Y., Chakrabarti, G., Kilgore, J. A., Silvers, M. A., Patidar, P. L., Cholka, A., Fattah, F., Cha, Y., Anderson, G. G., Kusko, R., Peyton, M., Yan, J., Xie, X. J., Sarode, V., Williams, N. S., Minna, J. D. & 4 others, Beg, M., Gerber, D. E., Bey, E. A. & Boothman, D. A., Dec 12 2016, In : Cancer Cell. 30, 6, p. 940-952 13 p.

Research output: Contribution to journalArticle

39 Scopus citations

LZTFL1 suppresses lung tumorigenesis by maintaining differentiation of lung epithelial cells

Wei, Q., Chen, Z. H., Wang, L., Zhang, T., Duan, L., Behrens, C., Wistuba, I. I., Minna, J. D., Gao, B., Luo, J. H. & Liu, Z. P., May 19 2016, In : Oncogene. 35, 20, p. 2655-2663 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

MiRNA-related genetic variations associated with radiotherapy-induced toxicities in patients with locally advanced non-small cell lung cancer

Li, R., Pu, X., Chang, J. Y., Ye, Y., Komaki, R., Minna, J. D., Roth, J. A., Han, B. & Wu, X., Mar 1 2016, In : PLoS One. 11, 3, e0150467.

Research output: Contribution to journalArticle

6 Scopus citations

Modulation of EZH2 expression by MEK-ERK or PI3K-AKT signaling in lung cancer is dictated by different KRAS oncogene mutations

Riquelme, E., Behrens, C., Lin, H. Y., Simon, G., Papadimitrakopoulou, V., Izzo, J., Moran, C., Kalhor, N., Jack Lee, J., Minna, J. D. & Wistuba, I. I., Feb 1 2016, In : Cancer research. 76, 3, p. 675-685 11 p.

Research output: Contribution to journalArticle

54 Scopus citations

Monitoring drug induced apoptosis and treatment sensitivity in non-small cell lung carcinoma using dielectrophoresis

Taruvai Kalyana Kumar, R., Liu, S., Minna, J. D. & Prasad, S., Sep 1 2016, In : Biochimica et Biophysica Acta - General Subjects. 1860, 9, p. 1877-1883 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Nicotinic acetylcholine receptor expression in human airway correlates with lung function

Lam, D. C. L., Luo, S. Y., Fu, K. H., Lui, M. M. S., Chan, K. H., Wistuba, I. I., Gao, B., Tsao, S. W., Ip, M. S. M. & Minna, J. D., Feb 1 2016, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 310, 3, p. L232-L239

Research output: Contribution to journalArticle

17 Scopus citations

Quantitative Secretomic Analysis Identifies Extracellular Protein Factors That Modulate the Metastatic Phenotype of Non-Small Cell Lung Cancer

Hu, R., Huffman, K. E., Chu, M., Zhang, Y., Minna, J. D. & Yu, Y., Feb 5 2016, In : Journal of Proteome Research. 15, 2, p. 477-486 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Selecting reliable mRNA expression measurements across platforms improves downstream analysis

Tong, P., Diao, L., Shen, L., Li, L., Heymach, J. V., Girard, L., Minna, J. D., Coombes, K. R., Byers, L. A. & Wang, J., 2016, In : Cancer Informatics. 15, p. 81-89 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Telomerase inhibitor imetelstat has preclinical activity across the spectrum of non-small cell lung cancer oncogenotypes in a telomere length dependent manner

Frink, R. E., Peyton, M., Schiller, J. H., Gazdar, A. F., Shay, J. W. & Minna, J. D., May 31 2016, In : Oncotarget. 7, 22, p. 31639-31651 13 p.

Research output: Contribution to journalArticle

22 Scopus citations

Torin2 suppresses ionizing radiation-induced DNA damage repair

Udayakumar, D., Pandita, R. K., Horikoshi, N., Liu, Y., Liu, Q., Wong, K. K., Hunt, C. R., Gray, N. S., Minna, J. D., Pandita, T. K. & Westover, K. D., May 1 2016, In : Radiation Research. 185, 5, p. 527-538 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Validation of SCT methylation as a hallmark biomarker for lung cancers

Zhang, Y. A., Ma, X., Sathe, A., Fujimoto, J., Wistuba, I. I., Lam, S., Yatabe, Y., Wang, Y. W., Stastny, V., Gao, B., Larsen, J. E., Girard, L., Liu, X., Song, K., Behrens, C., Kalhor, N., Xie, Y., Zhang, M. Q., Minna, J. D. & Gazdar, A. F., Mar 23 2016, In : Journal of Thoracic Oncology. 11, 3, p. 346-360 15 p.

Research output: Contribution to journalArticle

9 Scopus citations

XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer

Kim, J., McMillan, E., Kim, H. S., Venkateswaran, N., Makkar, G., Rodriguez-Canales, A., Villalobos, P., Neggers, J. E., Mendiratta, S., Wei, S., Landesman, Y., Senapedis, W., Baloglu, E., Chow, C. W. B., Frink, R. E., Gao, B., Roth, M., Minna, J. D., Daelemans, D., Wistuba, I. I. & 3 others, Posner, B. A., Scaglioni, P. P. & White, M. A., Sep 28 2016, In : Nature. 538, 7623, p. 114-117 4 p.

Research output: Contribution to journalArticle

86 Scopus citations

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer

Larsen, J. E., Nathan, V., Osborne, J. K., Farrow, R. K., Deb, D., Sullivan, J. P., Dospoy, P. D., Augustyn, A., Hight, S. K., Sato, M., Girard, L., Behrens, C., Wistuba, I. I., Gazdar, A. F., Hayward, N. K. & Minna, J. D., Sep 1 2016, In : Journal of Clinical Investigation. 126, 9, p. 3219-3235 17 p.

Research output: Contribution to journalArticle

108 Scopus citations
2015

A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression

Shields, B. B., Pecot, C. V., Gao, H., McMillan, E., Potts, M., Nagel, C., Purinton, S., Wang, Y., Ivan, C., Kim, H. S., Borkowski, R. J., Khan, S., Rodriguez-Aguayo, C., Lopez-Berestein, G., Lea, J., Gazdar, A., Baggerly, K. A., Sood, A. K. & White, M. A., Dec 1 2015, In : Molecular Systems Biology. 11, 12, p. 1-17 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

An integrated molecular analysis of lung adenocarcinomas identifies potential therapeutic targets among TTF1-negative tumors, including DNA Repair Proteins and Nrf2

Cardnell, R. J. G., Behrens, C., Diao, L., Fan, Y. H., Tang, X., Tong, P., Minna, J. D., Mills, G. B., Heymach, J. V., Wistuba, I. I., Wang, J. & Byers, L. A., Aug 1 2015, In : Clinical Cancer Research. 21, 15, p. 3480-3491 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

A systematic analysis reveals heterogeneous changes in the endocytic activities of cancer cells

Elkin, S. R., Bendris, N., Reis, C. R., Zhou, Y., Xie, Y., Huffman, K. E., Minna, J. D. & Schmid, S. L., Nov 1 2015, In : Cancer Research. 75, 21, p. 4640-4650 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Clinicopathologic features and outcomes of patients with lung adenocarcinomas harboring BRAF mutations in the Lung Cancer Mutation Consortium

Villaruz, L. C., Socinski, M. A., Abberbock, S., Berry, L. D., Johnson, B. E., Kwiatkowski, D. J., John Iafrate, A., Varella-Garcia, M., Franklin, W. A., Camidge, D. R., Sequist, L. V., Haura, E. B., Ladanyi, M., Kurland, B. F., Kugler, K., Minna, J. D., Bunn, P. A. & Kris, M. G., Feb 1 2015, In : Cancer. 121, 3, p. 448-456 9 p.

Research output: Contribution to journalArticle

65 Scopus citations

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

Skoulidis, F., Byers, L. A., Diao, L., Papadimitrakopoulou, V. A., Tong, P., Izzo, J., Behrens, C., Kadara, H., Parra, E. R., Canales, J. R., Zhang, J., Giri, U., Gudikote, J., Cortez, M. A., Yang, C., Fan, Y., Peyton, M., Girard, L., Coombes, K. R., Toniatti, C. & 17 others, Heffernan, T. P., Choi, M., Frampton, G. M., Miller, V., Weinstein, J. N., Herbst, R. S., Wong, K. K., Zhang, J., Sharma, P., Mills, G. B., Hong, W. K., Minna, J. D., Allison, J. P., Futrea, A., Wang, J., Wistuba, I. I. & Heymach, J. V., Aug 1 2015, In : Cancer discovery. 5, 8, p. 861-878 18 p.

Research output: Contribution to journalArticle

272 Scopus citations

Corrigendum: A pan-cancer proteomic perspective on the Cancer Genome Atlas

Akbani, R., Ng, P. K. S., Werner, H. M. J., Shahmoradgoli, M., Zhang, F., Ju, Z., Liu, W., Yang, J. Y., Yoshihara, K., Li, J., Ling, S., Seviour, E. G., Ram, P. T., Minna, J. D., Diao, L., Tong, P., Heymach, J. V., Hill, S. M., Dondelinger, F., Städler, N. & 9 others, Byers, L. A., Meric-Bernstam, F., Weinstein, J. N., Broom, B. M., Verhaak, R. G. W., Liang, H., Mukherjee, S., Lu, Y. & Mills, G. B., Jan 28 2015, In : Nature Communications. 6, 4852.

Research output: Contribution to journalArticle

6 Scopus citations

Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis

Pozo, K., Hillmann, A., Augustyn, A., Plattner, F., Hai, T., Singh, T., Ramezani, S., Sun, X., Pfragner, R., Minna, J. D., Cote, G. J., Chen, H., Bibb, J. A. & Nwariaku, F. E., 2015, In : Oncotarget. 6, 14, p. 12080-12093 14 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations
6 Scopus citations

Erratum: MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors (International Journal of Cancer (2009) 124:8 (1778-1784) DOI: 10.1002/ijc.24150)

Kubo, T., Yamamoto, H., Lockwood, W. W., Valencia, I., Soh, J., Peyton, M., Jida, M., Otani, H., Fujii, T., Ouchida, M., Takigawa, N., Kiura, K., Shimizu, K., Date, H., Minna, J. D., Varella-Garcia, M., Lam, W. L., Gazdar, A. F. & Toyooka, S., Jan 15 2015, In : International Journal of Cancer. 136, 2, p. E1

Research output: Contribution to journalArticle

Ethnicity affects EGFR and KRAS gene alterations of lung adenocarcinoma

Soh, J., Toyooka, S., Matsuo, K., Yamamoto, H., Wistuba, I. I., Lam, S., Fong, K. M., Gazdar, A. F. & Miyoshi, S., Sep 1 2015, In : Oncology Letters. 10, 3, p. 1775-1782 8 p.

Research output: Contribution to journalArticle

13 Scopus citations