The Nancy B. and Jake L. Hamon Center for Therapeutic Oncology Research

Research Output

Filter
Review article
2019

Artificial intelligence in lung cancer pathology image analysis

Wang, S., Yang, D. M., Rong, R., Zhan, X., Fujimoto, J., Liu, H., Minna, J., Wistuba, I. I., Xie, Y. & Xiao, G., Nov 2019, In : Cancers. 11, 11, 1673.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations
2017

Comprehensive evaluation of published gene expression prognostic signatures for biomarker-based lung cancer clinical studies

Tang, H., Wang, S., Xiao, G., Schiller, J., Papadimitrakopoulou, V., Minna, J., Wistuba, I. I. & Xie, Y., Apr 1 2017, In : Annals of Oncology. 28, 4, p. 733-740 8 p., mdw683.

Research output: Contribution to journalReview article

20 Scopus citations

Small-cell lung cancer: What we know, what we need to know and the path forward

Gazdar, A. F., Bunn, P. A. & Minna, J. D., Dec 1 2017, In : Nature Reviews Cancer. 17, 12, p. 725-737 13 p.

Research output: Contribution to journalReview article

129 Scopus citations
2016

Small cell lung cancer: Can recent advances in biology and molecular biology be translated into improved outcomes?

Bunn, P. A., Minna, J. D., Augustyn, A., Gazdar, A. F., Ouadah, Y., Krasnow, M. A., Berns, A., Brambilla, E., Rekhtman, N., Massion, P. P., Niederst, M., Peifer, M., Yokota, J., Govindan, R., Poirier, J. T., Byers, L. A., Wynes, M. W., McFadden, D. G., MacPherson, D., Hann, C. L. & 34 others, Farago, A. F., Dive, C., Teicher, B. A., Peacock, C. D., Johnson, J. E., Cobb, M. H., Wendel, H. G., Spigel, D., Sage, J., Yang, P., Pietanza, M. C., Krug, L. M., Heymach, J., Ujhazy, P., Zhou, C., Goto, K., Dowlati, A., Christensen, C. L., Park, K., Einhorn, L. H., Edelman, M. J., Giaccone, G., Gerber, D. E., Salgia, R., Owonikoko, T., Malik, S., Karachaliou, N., Gandara, D. R., Slotman, B. J., Blackhall, F., Goss, G., Thomas, R., Rudin, C. M. & Hirsch, F. R., Jan 1 2016, In : Journal of Thoracic Oncology. 11, 4, p. 453-474 22 p.

Research output: Contribution to journalReview article

76 Scopus citations
2014

Analysis of TP53 mutation status in human cancer cell lines: A reassessment

Leroy, B., Girard, L., Hollestelle, A., Minna, J. D., Gazdar, A. F. & Soussi, T., Jun 2014, In : Human mutation. 35, 6, p. 756-765 10 p.

Research output: Contribution to journalReview article

62 Scopus citations
2013

Molecular biology of lung cancer

Cooper, W. A., Lam, D. C. L., O'Toole, S. A. & Minna, J. D., 2013, In : Journal of Thoracic Disease. 5, SUPPL.5, p. S479-S490

Research output: Contribution to journalReview article

172 Scopus citations
2011

How do we safely get people to stop smoking?

Lam, D. C. L. & Minna, J. D., Nov 1 2011, In : Cancer Prevention Research. 4, 11, p. 1724-1727 4 p.

Research output: Contribution to journalReview article

1 Scopus citations

Molecular Biology of Lung Cancer: Clinical Implications

Larsen, J. E. & Minna, J. D., Dec 1 2011, In : Clinics in Chest Medicine. 32, 4, p. 703-740 38 p.

Research output: Contribution to journalReview article

122 Scopus citations

Targeted therapies for lung cancer: Clinical experience and novel agents

Larsen, J. E., Cascone, T., Gerber, D. E., Heymach, J. V. & Minna, J. D., Nov 1 2011, In : Cancer Journal. 17, 6, p. 512-527 16 p.

Research output: Contribution to journalReview article

77 Scopus citations
2010

ALK Inhibition for Non-Small Cell Lung Cancer: From Discovery to Therapy in Record Time

Gerber, D. E. & Minna, J. D., Dec 14 2010, In : Cancer Cell. 18, 6, p. 548-551 4 p.

Research output: Contribution to journalReview article

175 Scopus citations

Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy

Sullivan, J. P., Minna, J. D. & Shay, J. W., Mar 1 2010, In : Cancer and Metastasis Reviews. 29, 1, p. 61-72 12 p.

Research output: Contribution to journalReview article

127 Scopus citations

Lung cancer cell lines: Useless artifacts or invaluable tools for medical science?

Gazdar, A. F., Gao, B. & Minna, J. D., Jun 1 2010, In : Lung Cancer. 68, 3, p. 309-318 10 p.

Research output: Contribution to journalReview article

65 Scopus citations

Lung cancer cell lines as tools for biomedical discovery and research

Gazdar, A. F., Girard, L., Lockwood, W. W., Lam, W. L. & Minna, J. D., Sep 8 2010, In : Journal of the National Cancer Institute. 102, 17, p. 1310-1321 12 p.

Research output: Contribution to journalReview article

114 Scopus citations

Radiogenomics predicting tumor responses to radiotherapy in lung cancer

Das, A. K., Bell, M. H., Nirodi, C. S., Story, M. D. & Minna, J. D., Jul 1 2010, In : Seminars in Radiation Oncology. 20, 3, p. 149-155 7 p.

Research output: Contribution to journalReview article

23 Scopus citations

Tobacco and cancer: An American Association for Cancer Research policy statement

Viswanath, K., Herbst, R. S., Land, S. R., Leischow, S. J., Shields, P. G., Brandon, T. H., Fiore, M. C., Gritz, E. R., Hecht, S. S., Lerman, C., Minna, J. D. & Sidransky, D., May 1 2010, In : Cancer research. 70, 9, p. 3419-3430 12 p.

Research output: Contribution to journalReview article

46 Scopus citations
2008

Deregulated EGFR signaling during lung cancer progression: Mutations, amplicons, and autocrine loops

Gazdar, A. F. & Minna, J. D., Aug 1 2008, In : Cancer Prevention Research. 1, 3, p. 156-160 5 p.

Research output: Contribution to journalReview article

62 Scopus citations

Small-cell lung cancer: Translational research enroute to therapeutic advances

Dowell, J. & Minna, J. D., Nov 30 2008, In : ONCOLOGY. 22, 13, p. 1493+1495

Research output: Contribution to journalReview article

2 Scopus citations
2007

DNA methylation in health, disease, and cancer

Shames, D. S., Minna, J. D. & Gazdar, A. F., Feb 1 2007, In : Current molecular medicine. 7, 1, p. 85-102 18 p.

Research output: Contribution to journalReview article

147 Scopus citations

Genes regulating the sensitivity of solid tumor cell lines to cytotoxic agents: A literature review

Sekine, I., Minna, J. D., Nishio, K., Saijo, N. & Tamura, T., May 1 2007, In : Japanese Journal of Clinical Oncology. 37, 5, p. 329-336 8 p.

Research output: Contribution to journalReview article

13 Scopus citations

New molecularly targeted therapies for lung cancer

Sun, S., Schiller, J. H., Spinola, M. & Minna, J. D., Oct 1 2007, In : Journal of Clinical Investigation. 117, 10, p. 2740-2750 11 p.

Research output: Contribution to journalReview article

166 Scopus citations
2006

A literature review of molecular markers predictive of clinical response to cytotoxic chemotherapy in patients with lung cancer

Sekine, I., Minna, J. D., Nishio, K., Tamura, T. & Saijo, N., Jan 1 2006, In : Journal of Thoracic Oncology. 1, 1, p. 31-37 7 p.

Research output: Contribution to journalReview article

18 Scopus citations

EGFR mutations and molecularly targeted therapy: A new era in the treatment of lung cancer

Dowell, J. E. & Minna, J. D., Apr 1 2006, In : Nature Clinical Practice Oncology. 3, 4, p. 170-171 2 p.

Research output: Contribution to journalReview article

13 Scopus citations
2005

3p21.3 tumor suppressor cluster: Prospects for translational applications

Ji, L., Minna, J. D. & Roth, J. A., Jan 1 2005, In : Future Oncology. 1, 1, p. 79-92 14 p.

Research output: Contribution to journalReview article

72 Scopus citations
2004

A bull's eye for targeted lung cancer therapy

Minna, J. D., Gazdar, A. F., Sprang, S. R. & Herz, J., Jun 4 2004, In : Science. 304, 5676, p. 1458-1461 4 p.

Research output: Contribution to journalReview article

63 Scopus citations
11 Scopus citations
2003

A big step in the study of small cell lung cancer

Minna, J. D., Kurie, J. M. & Jacks, T., Sep 1 2003, In : Cancer Cell. 4, 3, p. 163-166 4 p.

Research output: Contribution to journalReview article

42 Scopus citations

Lung cancer · 9: Molecular biology of lung cancer: Clinical implications

Fong, K. M., Sekido, Y., Gazdar, A. F. & Minna, J. D., Oct 1 2003, In : Thorax. 58, 10, p. 892-900 9 p.

Research output: Contribution to journalReview article

107 Scopus citations

Molecular Genetics of Lung Cancer

Sekido, Y., Fong, K. M. & Minna, J. D., Nov 19 2003, In : Annual review of medicine. 54, p. 73-87 15 p.

Research output: Contribution to journalReview article

255 Scopus citations
2002

Focus on lung cancer

Minna, J. D., Roth, J. A. & Gazdar, A. F., Feb 2002, In : Cancer Cell. 1, 1, p. 49-52 4 p.

Research output: Contribution to journalReview article

335 Scopus citations

Molecular biology of lung cancer: Clinical implications

Fong, K. M. & Minna, J. D., Mar 2002, In : Clinics in Chest Medicine. 23, 1, p. 83-101 19 p.

Research output: Contribution to journalReview article

26 Scopus citations

Molecular pathogenesis of lung cancer

Zöchbauer-Müller, S., Gazdar, A. F. & Minna, J. D., Apr 9 2002, In : Annual review of physiology. 64, p. 681-708 28 p.

Research output: Contribution to journalReview article

165 Scopus citations

Molecular pathogenesis of lung cancer and potential translational applications.

Minna, J. D., Fong, K., Zöchbauer-Müller, S. & Gazdar, A. F., Jan 1 2002, In : Cancer journal (Sudbury, Mass.). 8 Suppl 1, p. S41-46

Research output: Contribution to journalReview article

55 Scopus citations

Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers

Zabarovsky, E. R., Lerman, M. I. & Minna, J. D., Jan 1 2002, In : Oncogene. 21-45, 5, p. 6915-6935 21 p.

Research output: Contribution to journalReview article

306 Scopus citations
2001

Molecular genetic abnormalities in the pathogenesis of human lung cancer

Forgacs, E., Zöchbauer-Müller, S., Oláh, E. & Minna, J. D., Jan 1 2001, In : Pathology and Oncology Research. 7, 1, p. 6-13 8 p.

Research output: Contribution to journalReview article

61 Scopus citations

Molecular genetics of small cell lung carcinoma

Wistuba, I. I., Gazdar, A. F. & Minna, J. D., Jan 1 2001, In : Seminars in oncology. 28, 2 SUPPL. 4, p. 3-13 11 p.

Research output: Contribution to journalReview article

297 Scopus citations
2000

The biology of lung cancer including potential clinical applications

Zochbauer-Muller, S. & Minna, J. D., Nov 22 2000, In : Chest surgery clinics of North America. 10, 4, p. 691-708 18 p.

Research output: Contribution to journalReview article

12 Scopus citations
1999

Enrichment of epithelial cells for molecular studies

Maitra, A., Wistuba, I. I., Virmani, A. K., Sakaguchi, M., Park, I., Stucky, A., Milchgrub, S., Gibbons, D., Minna, J. D. & Gazdar, A. F., Apr 1 1999, In : Nature medicine. 5, 4, p. 459-463 5 p.

Research output: Contribution to journalReview article

56 Scopus citations

Prevention of cancer in the next millennium: Report of the Chemoprevention Working Group to the American Association for Cancer Research

Alberts, D. S., Colvin, O. M., Conney, A. H., Ernster, V. L., Garber, J. E., Greenwald, P., Gudas, L. J., Waun Ki Hong, K. H., Kelloff, G. J., Kramer, R. A., Lerman, C. E., Mangelsdorf, D. J., Matter, A., Minna, J. D., Nelson V, W. G., Pezzuto, J. M., Prendergast, F., Rusch, V. W., Sporn, M. B., Wattenberg, L. W. & 1 others, Weinstein, I. B., Oct 1 1999, In : Cancer research. 59, 19, p. 4743-4758 16 p.

Research output: Contribution to journalReview article

162 Scopus citations
1997

Neuroendocrine tumors of the lung: Pathology and molecular biology

Vuitch, F., Sekido, Y., Fong, K., Mackay, B., Minna, J. D. & Gazdar, A. F., Jan 22 1997, In : Chest surgery clinics of North America. 7, 1, p. 21-47 27 p.

Research output: Contribution to journalReview article

28 Scopus citations
1993

Antioncogenes and human cancer

Carbone, D. P. & Minna, J. D., Jan 1 1993, In : Annual review of medicine. 44, p. 451-464 14 p.

Research output: Contribution to journalReview article

9 Scopus citations
1992

The molecular genetics of lung cancer.

Carbone, D. P. & Minna, J. D., 1992, In : Advances in internal medicine. 37, p. 153-171 19 p.

Research output: Contribution to journalReview article

57 Scopus citations
1990

Dominant oncogenes and tumor suppressor genes in the pathogenesis of lung cancer.

Viallet, J. & Minna, J. D., Mar 1990, In : American journal of respiratory cell and molecular biology. 2, 3, p. 225-232 8 p.

Research output: Contribution to journalReview article

62 Scopus citations
1989

Genetic changes in the pathogenesis of lung cancer

Birrer, M. J. & Minna, J. D., Jan 1 1989, In : Annual review of medicine. 40, p. 305-317 13 p.

Research output: Contribution to journalReview article

19 Scopus citations

Genetic events in the pathogenesis of lung cancer

Minna, J. D., Jan 1 1989, In : CHEST. 96, 1 SUPPL., p. 17S-23S

Research output: Contribution to journalReview article

18 Scopus citations
1988

Gastrin-releasing peptide and other autocrine growth factors in lung cancer: pathogenetic and treatment implications.

Minna, J. D., Cuttitta, F., Battey, J. F., Mulshine, J. L., Linnoila, I., Gazdar, A. F., Trepel, J. & Sausville, E. A., Jan 1 1988, In : Important advances in oncology. p. 55-64 10 p.

Research output: Contribution to journalReview article

11 Scopus citations
1986

Chromosomal deletion, gene amplification, alternative processing, and autocrine growth factor production in the pathogenesis of human lung cancer.

Minna, J. D., Battey, J. F., Birrer, M., Brooks, B. J., Cuttitta, F., DeGreve, J., Gazdar, A. F., Johnson, B. E., Nau, M. M. & Sausville, E. A., 1986, In : Princess Takamatsu symposia. 17, p. 109-122 14 p.

Research output: Contribution to journalReview article

3 Scopus citations
1985

Autocrine growth factors in human small cell lung cancer.

Cuttitta, F., Carney, D. N., Mulshine, J., Moody, T. W., Fedorko, J., Fischler, A. & Minna, J. D., 1985, In : Cancer surveys. 4, 4, p. 707-727 21 p.

Research output: Contribution to journalReview article

32 Scopus citations
1982

Small cell cancer of the lung

Carney, D. N. & Minna, J. D., Dec 1 1982, In : Clinics in Chest Medicine. 3, 2, p. 389-398 10 p.

Research output: Contribution to journalReview article

15 Scopus citations

The use of experimental systems in the therapeutic research of small cell lung cancer.

Carney, D. N., Gazdar, A. F. & Minna, J. D., Dec 1 1982, In : Pathobiology annual. 12, p. 115-136 22 p.

Research output: Contribution to journalReview article

1 Scopus citations
1980

Individual differences in cancer susceptibility

Harris, C. C., Mulvihill, J. J., Thorgeirsson, S. S. & Minna, J. D., Jan 1 1980, In : Annals of internal medicine. 92, 6, p. 809-825 17 p.

Research output: Contribution to journalReview article

48 Scopus citations