• 8086 Citations
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1976 …2020

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1976

Elimination of the sarcoma genome from murine sarcoma virus transformed cat cells

Frankel, A. E., Haapala, D. K., Neubauer, R. L. & Fischinger, P. J., Jan 1 1976, In : Science. 191, 4233, p. 1264-1266 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

Fractionation of DNA nucleotide transcripts from Moloney sarcoma virus and isolation of sarcoma virus specific complementary DNA

Frankel, A. E., Neubauer, R. L. & Fischinger, P. J., Dec 1 1976, In : Journal of virology. 18, 2, p. 481-490 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Nucleotide sequences in mouse DNA and RNA specific for Moloney sarcoma virus

Frankel, A. E. & Fischinger, P. J., Jan 1 1976, In : Proceedings of the National Academy of Sciences of the United States of America. 73, 10, p. 3705-3709 5 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations
1977

Effect of helper virus on the number of murine sarcoma virus DNA copies in infected mammalian cells

Frankel, A. E., Gilbert, J. H. & Fischinger, P. J., Dec 1 1977, In : Journal of virology. 23, 3, p. 492-502 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Rate of divergence of cellular sequences homologous to segments of Moloney sarcoma virus

Frankel, A. E. & Fischinger, P. J., Jan 1 1977, In : Journal of virology. 21, 1, p. 153-160 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
1978

Biological, immunological, and biochemical evidence that HIX virus is a recombinant between moloney leukemia virus and a murine xenotropic C type virus

Fischinger, P. J., Frankel, A. E., Elder, J. H., Lerner, R. A., Ihle, J. N. & Bolognesi, D. P., Oct 15 1978, In : Virology. 90, 2, p. 241-254 14 p.

Research output: Contribution to journalArticle

33 Scopus citations
1979

Nature and distribution of feline sarcoma virus nucleotide sequences

Frankel, A. E., Gilbert, J. H., Porzig, K. J., Scolnick, E. M. & Aaronson, S. A., Jan 1 1979, In : Unknown Journal. 30, 3, p. 821-827 7 p.

Research output: Contribution to journalArticle

Open Access
55 Scopus citations
1980

Differentiating hepatic abscess from tumor: Combined 111In white blood cell and 99mTc liver scans

Fawcett, H. D., Lantieri, R. L., Frankel, A. & McDougall, I. R., Jan 1 1980, In : American Journal of Roentgenology. 135, 1, p. 53-56 4 p.

Research output: Contribution to journalArticle

14 Scopus citations
1981

Biological, Immunological, and Molecular Properties of Revertants of Cat Cells Transformed by Murine Sarcoma Virus

Fischinger, P. J., Blevins, C. S., Frankel, A. E., Tuttle-Fuller, N., Haapala, D. K., Nomura, S. & Robey, W. G., Mar 1 1981, In : Cancer research. 41, 3, p. 958-965 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

The role of in-111 leukocyte scanning in pyoderma gangrenosum

Johnson, M. A., Wells, J., Frankel, A., Goris, M. L. & McDougall, I. R., Jan 1 1981, In : Unknown Journal. 6, 10, p. 491-494 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Thrombotic thrombocytopenic purpura: Prolonged coma with recovery of neurologic function with intensive plasma exchange

Frankel, A. E., Rubenstein, M. D. & Wall, R. T., Jun 1981, In : American Journal of Hematology. 10, 4, p. 387-390 4 p.

Research output: Contribution to journalArticle

11 Scopus citations
1982

Human prostate specific and shared differentiation antigens defined by monoclonal antibodies

Frankel, A. E., Rouse, R. V. & Herzenberg, L. A., Jan 1 1982, In : Proceedings of the National Academy of Sciences of the United States of America. 79, 3 I, p. 903-907 5 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Monoclonal Antibodies to a Human Prostate Antigen

Frankel, A. E., Rouse, R. V., Wang, M. C., Chu, T. M. & Herzenberg, L. A., Sep 1 1982, In : Cancer research. 42, 9, p. 3714-3718 5 p.

Research output: Contribution to journalArticle

40 Scopus citations
1983

A model scheme for human hematopoietic cell differentiation as determined by multiple markers of leukemia-lymphomas.

Minowada, J., Minato, K., Tatsumi, E., Sugimoto, T., Nakazawa, S., Ohnuma, T., Kubonishi, I., Miyoshi, I., Frankel, A. & Gallo, R. C., Jan 1 1983, In : Hamatologie und Bluttransfusion. 28, p. 348-350 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

IgA and IgM rheumatoid factors in serum, saliva and other secretions: Relationship to immunoglobulin ratios in systemic sicca syndrome and rheumatoid arthritis

Elkon, K. B., Gharavi, A. E., Patel, B. M., Hughes, G. R. & Frankel, A., Jun 2 1983, In : Clinical and Experimental Immunology. 52, 1, p. 75-84 10 p.

Research output: Contribution to journalArticle

52 Scopus citations
1984

Selection of monoclonal antibodies for the development of breast cancer selective immunotoxins

Frankel, A., Ring, D., Kaplan, D. & Bjorn, M., Jan 1 1984, In : Federation Proceedings. 43, 6, p. no. 11

Research output: Contribution to journalArticle

1985

Antibody-toxin hybrids: A clinical review of their use

Frankel, A. E., Oct 1985, In : Journal of Biological Response Modifiers. 4, 5, p. 437-446 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Breast cancer immunotoxins

Winkelhake, J., Frankel, A. E. & Ring, D., Jan 1 1985, In : Federation Proceedings. 44, 5, p. No. 7443

Research output: Contribution to journalArticle

1 Scopus citations

Characterization of immunotoxins active against ovarian cancer cell lines

Pirker, R., FitzGerald, D. J. P., Hamilton, T. C., Ozols, R. F., Laird, W., Frankel, A. E., Willingham, M. C. & Pastan, I., Jan 1 1985, In : Journal of Clinical Investigation. 76, 3, p. 1261-1267 7 p.

Research output: Contribution to journalArticle

Open Access
70 Scopus citations

Evaluation off Monoclonal Antibodies for the Development off Breast Cancer Immunotoxins

Bjorn, M. J., Ring, D. & Frankel, A., Mar 1 1985, In : Cancer Research. 45, 3, p. 1214-1221 8 p.

Research output: Contribution to journalArticle

101 Scopus citations

Monoclonal antobodies, benign breast disease, and breast cancer. A panel discussion

McGuire, W. L., Ceriani, R. L., Schlom, J. & Frankel, A. E., Jan 1 1985, In : Breast Cancer Research and Treatment. 6, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Tissue distribution of breast cancer-associated antigens defined by monoclonal antibodies

Frankel, A. E., Ring, D. B., Tringale, F. & Hsieh-Ma, S. T., Jun 1985, In : Journal of Biological Response Modifiers. 4, 3, p. 273-286 14 p.

Research output: Contribution to journalArticle

95 Scopus citations
1987

Antitumor Activity of an Immunotoxin in a Nude Mouse Model of Human Ovarian Cancer

Fitzgerald, D. J., Bjorn, M. J., Ferris, R. J., Winkelhake, J. L., Frankel, A. E., Hamilton, T. C., Ozols, R. F., Willingham, M. C. & Pastan, I., Mar 1987, In : Cancer Research. 47, 5, p. 1407-1410 4 p.

Research output: Contribution to journalArticle

55 Scopus citations

Humoral Immune Response to a Ricin A Chain Immunotoxin in Patients with Metastatic Melanoma

Herlter, A. A., Spitler, L. E. & Frankel, A. E., Jan 1 1987, In : Cancer Drug Delivery. 4, 4, p. 245-253 9 p.

Research output: Contribution to journalArticle

37 Scopus citations
1988

A phase I study of T101-ricin a chain immunotoxin in refractory chronic lymphocytic leukemia

Hertler, A. A., Schlossman, D. M., Borowitz, M. J., Laurent, G., Jansen, F. K., Schmidt, C. & Frankel, A. E., Feb 1988, In : Journal of Biological Response Modifiers. 7, 1, p. 97-113 17 p.

Research output: Contribution to journalArticle

71 Scopus citations

Treatment of leukemia patients with T101 ricin A chain immunotoxins.

Laurent, G., Frankel, A. E., Hertler, A. A., Schlossman, D. M., Casellas, P. & Jansen, F. K., Dec 1 1988, In : Cancer treatment and research. 37, p. 483-491 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
1989

An anti‐CD5 immunotoxin for chronic lymphocytic leukemia: Enhancement of cytotoxicity with human serum albumin‐monensin

Hertler, A. A., Schlossman, D. M., Borowitz, M. J., Blythman, H. E., Casellas, P. & Frankel, A. E., Feb 15 1989, In : International Journal of Cancer. 43, 2, p. 215-219 5 p.

Research output: Contribution to journalArticle

53 Scopus citations

An immunotoxin for the treatment of T-acute lymphoblastic leukemic meningitis: studies in rhesus monkeys

Hertler, A. A., Schlossman, D. M., Borowitz, M. J., Poplack, D. G. & Frankel, A. E., Jan 1 1989, In : Cancer Immunology Immunotherapy. 28, 1, p. 59-66 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Distribution and Physical Properties of BCA200, a Mr 200,000 Glycoprotein Selectively Associated with Human Breast Cancer

Ring, D. B., Kassel, J. A., Hsieh-Ma, S. T., Bjorn, M. J., Tringale, F., Eaton, A. M., Reid, S. A., Frankel, A. E. & Nadji, M., Jun 1 1989, In : Cancer research. 49, 11, p. 3070-3080 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Phase I Evaluation of an Anti-Breast Carcinoma Monoclonal Antibody 260F9-Recombinant Ricin A Chain Immunoconjugate

Weiner, L. M., O'Dwyer, J., Kitson, J., Comis, R. L., Frankel, A. E., Bauer, R. J., Konrad, M. S. & Groves, E. S., Jul 15 1989, In : Cancer Research. 49, 14, p. 4062-4067 6 p.

Research output: Contribution to journalArticle

109 Scopus citations

Phase I study of an anti-breast cancer immunotoxin by continuous infusion: Report of a targeted toxic effect not predicted by animal studies

Gould, B. J., Borowitz, M. J., Groves, E. S., Carter, P. W., Anthony, D., Weiner, L. M. & Frankel, A. E., May 22 1989, In : Journal of the National Cancer Institute. 81, 10, p. 775-781 7 p.

Research output: Contribution to journalArticle

98 Scopus citations

Role of glutamic acid 177 of the ricin toxin A chain in enzymatic inactivation of ribosomes.

Schlossman, D., Withers, D., Welsh, P., Alexander, A., Robertus, J. & Frankel, A., Nov 1989, In : Molecular and cellular biology. 9, 11, p. 5012-5021 10 p.

Research output: Contribution to journalArticle

Open Access
72 Scopus citations

Selection and characterization of ricin toxin A-chain mutations in Saccharomyces cerevisiae.

Frankel, A., Schlossman, D., Welsh, P., Hertler, A., Withers, D. & Johnston, S., Feb 1989, In : Molecular and cellular biology. 9, 2, p. 415-420 6 p.

Research output: Contribution to journalArticle

Open Access
40 Scopus citations
1990

Role of arginine 180 and glutamic acid 177 of ricin toxin a chain in enzymatic inactivation of ribosomes

Frankel, A., Welsh, P., Richardson, J. & Robertus, J. D., Jan 1 1990, In : Molecular and cellular biology. 10, 12, p. 6257-6263 7 p.

Research output: Contribution to journalArticle

Open Access
90 Scopus citations
1991

Advances in immunotoxins

Oeltmann, T. N. & Frankel, A. E., Sep 4 1991, In : FASEB Journal. 5, 10, p. 2334-2337 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

Alteration of an amino acid residue outside the active site of the ricin A chain reduces its toxicity towards yeast ribosomes

Gould, J. H., Hartley, M. R., Welsh, P. C., Hoshizaki, D. K., Frankel, A., Roberts, L. M. & Lord, J. M., Nov 1 1991, In : MGG Molecular & General Genetics. 230, 1-2, p. 81-90 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Clinical evaluation of intraperitoneal Pseudomonas exotoxin immunoconjugate OVB3-PE in patients with ovarian cancer

Pai, L. H., Bookman, M. A., Ozols, R. F., Young, R. C., Smith, J. W., Longo, D. L., Gould, B., Frankel, A., McClay, E. F., Howell, S., Reed, E., Willingham, M. C., FitzGerald, D. J. & Pastan, I., Jan 1 1991, In : Journal of Clinical Oncology. 9, 12, p. 2095-2103 9 p.

Research output: Contribution to journalArticle

98 Scopus citations

Immunotoxins in the therapy of leukemias and lymphomas

Hertler, A. A. & Frankel, A. E., Jan 1 1991, In : Cancer Investigation. 9, 2, p. 211-219 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Phase I trial of H65-RTA immunoconjugate in patients with cutaneous T-cell lymphoma

LeMaistre, C. F., Rosen, S., Frankel, A., Kornfeld, S., Saria, E., Meneghetti, C., Drajesk, J., Fishwild, D., Scannon, P. & Byers, V., Jan 1 1991, In : Blood. 78, 5, p. 1173-1182 10 p.

Research output: Contribution to journalArticle

90 Scopus citations
1992

High-level expression and simplified purification of recombinant ricin A chain

Li, B. Y., Frankel, A. E. & Ramakrishnan, S., Oct 1992, In : Protein Expression and Purification. 3, 5, p. 386-394 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Structure of a Ricin Mutant Showing Rescue of Activity by a Noncatalytic Residue

Kim, Y., Mlsna, D., Monzingo, A. F., Ready, M. P., Frankel, A. & Robertus, J. D., Jan 1 1992, In : Biochemistry. 31, 12, p. 3294-3296 3 p.

Research output: Contribution to journalArticle

55 Scopus citations
1994

Expression of active, processed ricin in transgenic tobacco

Sehnke, P. C., Pedrosa, L., Paul, A. L., Frankel, A. E. & Ferl, R. J., Sep 9 1994, In : Journal of Biological Chemistry. 269, 36, p. 22473-22476 4 p.

Research output: Contribution to journalArticle

25 Scopus citations

Expression of Oligohistidine-Tagged Ricin B Chain in Spodoptera frugiperda

Afrin, L. B., Gulick, H., Vesely, J., Willingham, M. & Frankel, A. E., Nov 1 1994, In : Bioconjugate Chemistry. 5, 6, p. 539-546 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Expression of ricin B chain in Spodoptera frugiperda

Frankel, A., Roberts, H., Afrin, L., Vesely, J. & Willingham, M., Jan 1 1994, In : Biochemical Journal. 303, 3, p. 787-794 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Renaturated ricin toxin B chain made in Escherichia coli is soluble, stable, and biologically active

Tonevitsky, A., Toptygin, A., Agapov, I., Pfueller, U. & Frankel, A., Jan 1 1994, In : Biochemistry and Molecular Biology International. 32, 6, p. 1139-1146 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Vliianie glikozilirovaniia na strukturu, stabil'nost' i biologicheskuiu aktivnost' B-sub''edinitsy ritsina.

Translated title of the contribution: The effect of glycosylation on the structure, stability, and biological activity of the ricin B-subunitTonevitskiǐ, A. G., Toptygin, A. I., Agapov, I. I., Bushueva, T. L., Shamshnev, A. T., Frankel', A. & Debabov, V. G., Jun 1 1994, In : Doklady Akademii nauk / [Rossiiskaia akademii nauk]. 336, 5, p. 700-703 4 p.

Research output: Contribution to journalArticle

1995

Characterization of an Ovarian Cancer Activating Factor in Ascites From Ovarian Cancer Patients

Xu, Y., Gaudette, D. C., Boynton, J. D., Frankel, A., Fang, X. J., Sharma, A., Hurteau, J., Casey, G., Goodbody, A., Mellors, A., Holub, B. J. & Mills, G. B., Oct 1 1995, In : Clinical Cancer Research. 1, 10, p. 1223-1232 10 p.

Research output: Contribution to journalArticle

284 Scopus citations

Clinical trials of targeted toxins

Frankel, A. E., Tagge, E. P. & Willingham, M. C., Jan 1 1995, In : Seminars in Cancer Biology. 6, 5, p. 307-317 11 p.

Research output: Contribution to journalArticle

60 Scopus citations

IL2-Ricin Fusion Toxin is Selectively Cytotoxic in Vitro to IL2 Receptor-Bearing Tumor Cells

Frankel, A., Tagge, E., Chandler, J., Burbage, C., Hancock, G., Vesely, J. & Willingham, M., Jan 1 1995, In : Bioconjugate Chemistry. 6, 6, p. 666-672 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Recombinant ricin B chain produced in Escherichia coli is biologically active

Tonevitsky, A. G., Toptygin Yu., A., Agapov, I. I., Rakhmanova, V. A., Shamshiev, A. T., Alekseev Yu., O., Pfuller, U. & Frankel, A., Jan 1 1995, In : Molekulyarnaya Biologiya. 29, 2, p. 398-406 9 p.

Research output: Contribution to journalArticle