• 8086 Citations
  • 47 h-Index
1976 …2020

Research output per year

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Research Output

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Review article
2020

The human microbiota in multiple myeloma and proteasome inhibitors

Alkharabsheh, O., Sidiqi, M. H., Aljama, M. A., Gertz, M. A. & Frankel, A. E., Mar 1 2020, In : Acta Haematologica. 143, 2, p. 118-123 6 p.

Research output: Contribution to journalReview article

Open Access
2019

Cancer Immune Checkpoint Inhibitor Therapy and the Gut Microbiota

Frankel, A. E., Deshmukh, S., Reddy, A., Lightcap, J., Hayes, M., McClellan, S., Singh, S., Rabideau, B., Glover, T. G., Roberts, B. & Koh, A., Apr 1 2019, In : Integrative Cancer Therapies. 18

Research output: Contribution to journalReview article

Open Access
3 Scopus citations
Open Access
7 Scopus citations

Roles of the cGAS-STING pathway in cancer immunosurveillance and immunotherapy

Yum, S., Li, M., Frankel, A. E. & Chen, Z. J., Jan 1 2019, In : Annual Review of Cancer Biology. 3, 1, p. 323-344 22 p.

Research output: Contribution to journalReview article

2014

CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies

Testa, U., Pelosi, E. & Frankel, A., Feb 10 2014, In : Biomarker Research. 2, 1, 4.

Research output: Contribution to journalReview article

Open Access
94 Scopus citations
2013

Red blood cell-encapsulated L-asparaginase: Potential therapy of patients with asparagine synthetase deficient acute myeloid leukemia

Agrawal, V., Woo, J. H., Borthakur, G., Kantarjian, H. & Frankel, A. E., Apr 1 2013, In : Protein and Peptide Letters. 20, 4, p. 392-402 11 p.

Research output: Contribution to journalReview article

32 Scopus citations
2012

Arginine deprivation therapy for malignant melanoma

Yoon, J. K., Frankel, A. E., Feun, L. G., Ekmekcioglu, S. & Kim, K. B., Dec 21 2012, In : Clinical Pharmacology: Advances and Applications. 5, 1, p. 11-19 9 p.

Research output: Contribution to journalReview article

19 Scopus citations

Targeting methionine auxotrophy in cancer: Discovery & exploration

Agrawal, V., Alpini, S. E. J., Stone, E. M., Frenkel, E. P. & Frankel, A. E., Jan 1 2012, In : Expert Opinion on Biological Therapy. 12, 1, p. 53-61 9 p.

Research output: Contribution to journalReview article

17 Scopus citations
2010

Cytotoxic therapy with diphtheria toxin fusion proteins

Woo, J. H., Frankel, A. & Neville, D. M., Oct 1 2010, In : Drugs of the Future. 35, 10, p. 823-831 9 p.

Research output: Contribution to journalReview article

2 Scopus citations
2009

Anti-CD3 recombinant diphtheria immunotoxin therapy of cutaneous T cell lymphoma

Frankel, A. E., Zuckero, S. L., Mankin, A. A., Grable, M., Mitchell, K., Lee, Y. J., Neville, D. M. & Woo, J. H., May 18 2009, In : Current Drug Targets. 10, 2, p. 104-109 6 p.

Research output: Contribution to journalReview article

41 Scopus citations
2008

c-Met targeted therapy of cholangiocarcinoma

Socoteanu, M. P., Mott, F., Alpini, G. & Frankel, A. E., May 21 2008, In : World Journal of Gastroenterology. 14, 19, p. 2990-2994 5 p.

Research output: Contribution to journalReview article

24 Scopus citations

Potent inhibition of tumor angiogenesis by the matrix metalloproteinase- activated anthrax lethal toxin: Implications for broad anti-tumor efficacy

Alfano, R. W., Leppla, S. H., Liu, S., Bugge, T. H., Duesbery, N. S. & Frankel, A. E., Mar 15 2008, In : Cell Cycle. 7, 6, p. 745-749 5 p.

Research output: Contribution to journalReview article

Open Access
23 Scopus citations
2007

Hormono- et immunotoxines pour détruire les cellules cancéreuses

Translated title of the contribution: Hormone and immunotoxins to destroy cancer cellsFrankel, A. E. & Gillet, D., Apr 1 2007, In : Biofutur. 276, p. 31-34 4 p.

Research output: Contribution to journalReview article

2004

Induction of apoptosis by tumor cell-targeted toxins

Thorburn, A., Thorburn, J. & Frankel, A. E., Jan 1 2004, In : Apoptosis. 9, 1, p. 19-25 7 p.

Research output: Contribution to journalReview article

23 Scopus citations
2003

DAB389EGF fusion protein therapy of refractory glioblastoma multiforme

Cohen, K. A., Liu, T., Bissonette, R., Puri, R. K. & Frankel, A. E., Feb 1 2003, In : Current Pharmaceutical Biotechnology. 4, 1, p. 39-49 11 p.

Research output: Contribution to journalReview article

39 Scopus citations

DAB389IL2 (ONTAK®) fusion protein therapy of chronic lymphocytic leukaemia

Frankel, A. E., Fleming, D. R., Powell, B. L. & Gartenhaus, R., Feb 1 2003, In : Expert Opinion on Biological Therapy. 3, 1, p. 179-186 8 p.

Research output: Contribution to journalReview article

32 Scopus citations

Metastatic melanoma and matrix metalloproteinases

Riedlinger, G., Kridel, S., Al-Housseini, A. M., Brow, J. M., Bugge, T. H., Leppla, S. H., Duesbery, N., Vande Woude, G. & Frankel, A., Sep 1 2003, In : Drugs of the Future. 28, 9, p. 897-904 8 p.

Research output: Contribution to journalReview article

2 Scopus citations

Novel protein targeted therapy of metastatic melanoma

Frankel, A. E., Koo, H. M., Leppla, S. H., Duesbery, N. S. & Vande Woude, G. F., Sep 29 2003, In : Current Pharmaceutical Design. 9, 25, p. 2060-2066 7 p.

Research output: Contribution to journalReview article

18 Scopus citations

Recombinant toxin DAB389EGF is cytotoxic to human pancreatic cancer cells

Mishra, G., Lu, T. F. & Frankel, A. E., Oct 1 2003, In : Expert Opinion on Biological Therapy. 3, 7, p. 1173-1180 8 p.

Research output: Contribution to journalReview article

11 Scopus citations
2002

Anthrax fusion protein therapy of cancer

Frankel, A. E., Powell, B. L., Duesbery, N. S., Vande Woude, G. F. & Leppla, S. H., Jul 27 2002, In : Current Protein and Peptide Science. 3, 4, p. 399-407 9 p.

Research output: Contribution to journalReview article

18 Scopus citations

Diphtheria fusion protein therapy of chemoresistant malignancies

Frankel, A. E., Rossi, P., Kuzel, T. M. & Foss, F., Jun 24 2002, In : Current Cancer Drug Targets. 2, 1, p. 19-36 18 p.

Research output: Contribution to journalReview article

35 Scopus citations

Diphtheria toxin conjugate therapy of cancer.

Frankel, A. E., Powell, B. L. & Lilly, M. B., 2002, In : Cancer chemotherapy and biological response modifiers. 20, p. 301-313 13 p.

Research output: Contribution to journalReview article

41 Scopus citations
2001

Chimeric fusion proteins - Diphtheria toxin-based

Frankel, A. E., Powell, B. L., Vallera, D. A. & Neville D.M., J., Oct 1 2001, In : Current Opinion in Investigational Drugs. 2, 9, p. 1294-1301 8 p.

Research output: Contribution to journalReview article

10 Scopus citations

Novel therapeutics for chemotherapy-resistant acute myeloid leukaemia

Frankel, A. E., Schuster, M. W. & Jurcic, J. G., Jan 1 2001, In : BioDrugs. 15, 1, p. 55-71 17 p.

Research output: Contribution to journalReview article

3 Scopus citations
2000

Cell surface receptor-targeted therapy of acute myeloid leukemia: A review

Frankel, A. E., Sievers, E. L. & Scheinberg, D. A., Jan 1 2000, In : Cancer Biotherapy and Radiopharmaceuticals. 15, 5, p. 459-476 18 p.

Research output: Contribution to journalReview article

15 Scopus citations
1998

Conclusions

Frankel, A. E. & Willingham, M. C., Jun 4 1998, In : Current topics in microbiology and immunology. 234, p. 115-120 6 p.

Research output: Contribution to journalReview article

3 Scopus citations
1996

Genetic engineering of immunotoxins

Chandler, J. C., Frankel, A. E. & Tagge, E. P., Aug 27 1996, In : Seminars in Pediatric Surgery. 5, 3, p. 206-211 6 p.

Research output: Contribution to journalReview article

2 Scopus citations

Molecular biology and the pediatric surgeon: Definitions and basic methodology

Tagge, E. P., Tagge, D. U., Chandler, J. C., Pitre, B. R., Haddad, G., Frankel, A. E., Willingham, M. C., Garvin, A. J. & Papas, T. S., Aug 27 1996, In : Seminars in Pediatric Surgery. 5, 3, p. 139-148 10 p.

Research output: Contribution to journalReview article

1993

Immunotoxin therapy of cancer

Frankel, A. E., Jan 1 1993, In : ONCOLOGY. 7, 5, p. 69-78 10 p.

Research output: Contribution to journalReview article

21 Scopus citations
1992

Genetically engineered toxins in perspective.

Olsnes, S. & Frankel, A. E., 1992, In : Targeted diagnosis and therapy. 7, p. 465-477 13 p.

Research output: Contribution to journalReview article

1989

Immunotoxins: a clinical review of their use in the treatment of malignancies

Hertler, A. A. & Frankel, A. E., Jan 1 1989, In : Journal of Clinical Oncology. 7, 12, p. 1932-1942 11 p.

Research output: Contribution to journalReview article

91 Scopus citations
1988

Immunotoxin preparation and testing in vitro.

Frankel, A. E., Welsh, P. C., Withers, D. I. & Schlossman, D. M., 1988, In : Targeted diagnosis and therapy. 1, p. 225-244 20 p.

Research output: Contribution to journalReview article

5 Scopus citations
1986

Prospects for immunotoxin therapy in cancer.

Frankel, A. E., Houston, L. L., Issell, B. F. & Fathman, G., 1986, In : Annual review of medicine. 37, p. 125-142 18 p.

Research output: Contribution to journalReview article

51 Scopus citations