Audrey N Chang

  • 562 Citations
  • 13 h-Index
20052018
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2005 2018

  • 562 Citations
  • 13 h-Index
  • 21 Article
Filter
Article
2018
2 Citations (Scopus)

Similar biophysical abnormalities in glomeruli and podocytes from two distinct models

Embry, A. E., Liu, Z., Henderson, J. M., Byfield, F. J., Liu, L., Yoon, J., Wu, Z., Cruz, K., Moradi, S., Gillombardo, C. B., Hussain, R. Z., Doelger, R., Stuve, O., Chang, A. N., Janmey, P. A., Bruggeman, L. A. & Miller, R. T., May 1 2018, In : Journal of the American Society of Nephrology. 29, 5, p. 1501-1512 12 p.

Research output: Contribution to journalArticle

Podocytes
Protamines
Collagen
Wounds and Injuries
Hemodynamics
1 Citation (Scopus)

The dominant protein phosphatase PP1c isoform in smooth muscle cells, PP1cβ, is essential for smooth muscle contraction

Chang, A. N., Gao, N., Liu, Z., Huang, J., Nairn, A. C., Kamm, K. E. & Stull, J. T., Jan 1 2018, In : Journal of Biological Chemistry. 293, 43, p. 16677-16686 10 p.

Research output: Contribution to journalArticle

Protein Phosphatase 1
Muscle Proteins
Phosphoprotein Phosphatases
Muscle Contraction
Smooth Muscle Myocytes
2017
7 Citations (Scopus)

Physiological vs. pharmacological signalling to myosin phosphorylation in airway smooth muscle

Gao, N., Tsai, M. H., Chang, A. N., He, W., Chen, C. P., Zhu, M., Kamm, K. E. & Stull, J. T., Oct 1 2017, In : Journal of Physiology. 595, 19, p. 6231-6247 17 p.

Research output: Contribution to journalArticle

Myosins
Smooth Muscle
Phosphorylation
Pharmacology
Myosin-Light-Chain Phosphatase
2 Citations (Scopus)
Vascular Diseases
Smooth Muscle
Actins
Fibroblasts
Mutation
2016
13 Citations (Scopus)

Cardiac myosin light chain is phosphorylated by Ca2+/calmodulin-dependent and -independent kinase activities

Chang, A. N., Mahajan, P., Knapp, S., Barton, H., Sweeney, H. L., Kamm, K. E. & Stull, J. T., Jul 5 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 27, p. E3824-E3833

Research output: Contribution to journalArticle

Cardiac Myosins
Myosin-Light-Chain Kinase
Myosin Light Chains
Calmodulin
Phosphotransferases
13 Citations (Scopus)

Physiological signalling to myosin phosphatase targeting subunit-1 phosphorylation in ileal smooth muscle

Gao, N., Chang, A. N., He, W., Chen, C. P., Qiao, Y. N., Zhu, M., Kamm, K. E. & Stull, J. T., Jun 15 2016, In : Journal of Physiology. 594, 12, p. 3209-3225 17 p.

Research output: Contribution to journalArticle

Myosin-Light-Chain Phosphatase
Smooth Muscle
Phosphorylation
Myosin-Light-Chain Kinase
Light
7 Citations (Scopus)
Myosin-Light-Chain Phosphatase
Phosphorylation
Cardiac Myosins
Light
Heart Failure
2015
29 Citations (Scopus)

Constitutive phosphorylation of cardiac myosin regulatory light chain in vivo

Chang, A. N., Battiprolu, P. K., Cowley, P. M., Chen, G., Gerard, R. D., Pinto, J. R., Hill, J. A., Baker, A. J., Kamm, K. E. & Stull, J. T., Apr 24 2015, In : Journal of Biological Chemistry. 290, 17, p. 10703-10716 14 p.

Research output: Contribution to journalArticle

Cardiac Myosins
Myosin Light Chains
Phosphorylation
Myosin-Light-Chain Phosphatase
Myosin-Light-Chain Kinase
10 Citations (Scopus)

The α<inf>1</inf>A-adrenergic receptor subtype mediates increased contraction of failing right ventricular myocardium

Cowley, P. M., Wang, G., Chang, A. N., Makwana, O., Swigart, P. M., Lovett, D. H., Stull, J. T., Simpson, P. C. & Baker, A. J., Sep 3 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 309, 5, p. H888-H896

Research output: Contribution to journalArticle

Adrenergic Receptors
Heart Ventricles
Myocardium
Phenylephrine
A 61603
2014
19 Citations (Scopus)

Constitutive phosphorylation of myosin phosphatase targeting subunit-1 in smooth muscle

Tsai, M. H., Chang, A. N., Huang, J., He, W., Sweeney, H. L., Zhu, M., Kamm, K. E. & Stull, J. T., Jul 15 2014, In : Journal of Physiology. 592, 14, p. 3031-3051 21 p.

Research output: Contribution to journalArticle

Myosin-Light-Chain Phosphatase
Smooth Muscle
Phosphorylation
Myosin-Light-Chain Kinase
Carbachol
15 Citations (Scopus)

Long term ablation of protein Kinase a (PKA)-mediated cardiac troponin I phosphorylation leads to excitation-contraction uncoupling and diastolic dysfunction in a knock-in mouse model of hypertrophic cardiomyopathy

Dweck, D., Sanchez-Gonzalez, M. A., Chang, A. N., Dulce, R. A., Badger, C. D., Koutnik, A. P., Ruiz, E. L., Griffin, B., Liang, J., Kabbaj, M., Fincham, F. D., Hare, J. M., Michael Overton, J. & Pinto, J. R., Aug 15 2014, In : Journal of Biological Chemistry. 289, 33, p. 23097-23111 15 p.

Research output: Contribution to journalArticle

Phosphorylation
Troponin I
Hypertrophic Cardiomyopathy
Ablation
Protein Kinases
33 Citations (Scopus)

Recombinant neuregulin 1 does not activate cardiomyocyte DNA synthesis in normal or infarcted adult mice

Reuter, S., Soonpaa, M. H., Firulli, A. B., Chang, A. N. & Field, L. J., Dec 29 2014, In : PLoS One. 9, 12, e115871.

Research output: Contribution to journalArticle

Neuregulins
Neuregulin-1
Cardiac Myocytes
synthesis
DNA
8 Citations (Scopus)

Structural and protein interaction effects of hypertrophic and dilated cardiomyopathic mutations in alpha-tropomyosin

Chang, A. N., Greenfield, N. J., Singh, A., Potter, J. D. & Pinto, J. R., 2014, In : Frontiers in Physiology. 5, DEC, 460.

Research output: Contribution to journalArticle

Tropomyosin
Myosins
Hypertrophic Cardiomyopathy
Dilated Cardiomyopathy
Mutation
2013
9 Citations (Scopus)

The Effects of Neuregulin on Cardiac Myosin Light Chain Kinase Gene-Ablated Hearts

Chang, A. N., Huang, J., Battiprolu, P. K., Hill, J. A., Kamm, K. E. & Stull, J. T., Jun 11 2013, In : PLoS One. 8, 6, e66720.

Research output: Contribution to journalArticle

Neuregulins
myosin light chain kinase
Cardiac Myosins
Myosin-Light-Chain Kinase
Phosphorylation
15 Citations (Scopus)

Top-down mass spectrometry on tissue extracts and biofluids with isoelectric focusing and superficially porous silica liquid chromatography

Zhang, J., Roth, M. J., Chang, A. N., Plymire, D. A., Corbett, J. R., Greenberg, B. M. & Patrie, S. M., Nov 5 2013, In : Analytical Chemistry. 85, 21, p. 10377-10384 8 p.

Research output: Contribution to journalArticle

Tissue Extracts
Liquid chromatography
Silicon Dioxide
Mass spectrometry
Proteins
2011
28 Citations (Scopus)

Sensitive and reproducible intact mass analysis of complex protein mixtures with superficially porous capillary reversed-phase liquid chromatography mass spectrometry

Roth, M. J., Plymire, D. A., Chang, A. N., Kim, J., Maresh, E. M., Larson, S. E. & Patrie, S. M., Dec 15 2011, In : Analytical Chemistry. 83, 24, p. 9586-9592 7 p.

Research output: Contribution to journalArticle

Liquid chromatography
Mass spectrometry
Proteins
Histones
Labels
2010
21 Citations (Scopus)

Cardiac myosin is a substrate for Zipper-interacting Protein Kinase (ZIPK)

Chang, A. N., Chen, G., Gerard, R. D., Kamm, K. E. & Stull, J. T., Feb 19 2010, In : Journal of Biological Chemistry. 285, 8, p. 5122-5126 5 p.

Research output: Contribution to journalArticle

Cardiac Myosins
Fasteners
Protein Kinases
Light
Substrates
134 Citations (Scopus)

Mutations in Troponin that cause HCM, DCM AND RCM: What can we learn about thin filament function?

Willott, R. H., Gomes, A. V., Chang, A. N., Parvatiyar, M. S., Pinto, J. R. & Potter, J. D., May 2010, In : Journal of Molecular and Cellular Cardiology. 48, 5, p. 882-892 11 p.

Research output: Contribution to journalArticle

Troponin
Mutation
Restrictive Cardiomyopathy
Hypertrophic Cardiomyopathy
Dilated Cardiomyopathy
2008
28 Citations (Scopus)

Troponin and cardiomyopathy

Chang, A. N., Parvatiyar, M. S. & Potter, J. D., Apr 25 2008, In : Biochemical and Biophysical Research Communications. 369, 1, p. 74-81 8 p.

Research output: Contribution to journalArticle

Troponin
Cardiomyopathies
Mutation
Restrictive Cardiomyopathy
Muscle
2005
69 Citations (Scopus)

Functional consequences of hypertrophic and dilated cardiomyopathy-causing mutations in α-tropomyosin

Chang, A. N., Harada, K., Ackerman, M. J. & Potter, J. D., Oct 7 2005, In : Journal of Biological Chemistry. 280, 40, p. 34343-34349 7 p.

Research output: Contribution to journalArticle

Tropomyosin
Hypertrophic Cardiomyopathy
Dilated Cardiomyopathy
Adenosine Triphosphatases
Mutation
99 Citations (Scopus)

Sarcomeric protein mutations in dilated cardiomyopathy

Chang, A. N. & Potter, J. D., Sep 2005, In : Heart Failure Reviews. 10, 3, p. 225-235 11 p.

Research output: Contribution to journalArticle

Dilated Cardiomyopathy
Sarcomeres
Mutation
Cytoskeleton
Proteins