Audrey N Chang

  • 570 Citations
  • 13 h-Index
20052018

Research output per year

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Research Output

  • 570 Citations
  • 13 h-Index
  • 21 Article
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Article
2005

Functional consequences of hypertrophic and dilated cardiomyopathy-causing mutations in α-tropomyosin

Chang, A. N., Harada, K., Ackerman, M. J. & Potter, J. D., Oct 7 2005, In : Journal of Biological Chemistry. 280, 40, p. 34343-34349 7 p.

Research output: Contribution to journalArticle

69 Scopus citations

Sarcomeric protein mutations in dilated cardiomyopathy

Chang, A. N. & Potter, J. D., Sep 2005, In : Heart Failure Reviews. 10, 3, p. 225-235 11 p.

Research output: Contribution to journalArticle

99 Scopus citations
2008

Troponin and cardiomyopathy

Chang, A. N., Parvatiyar, M. S. & Potter, J. D., Apr 25 2008, In : Biochemical and Biophysical Research Communications. 369, 1, p. 74-81 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2010

Cardiac myosin is a substrate for Zipper-interacting Protein Kinase (ZIPK)

Chang, A. N., Chen, G., Gerard, R. D., Kamm, K. E. & Stull, J. T., Feb 19 2010, In : Journal of Biological Chemistry. 285, 8, p. 5122-5126 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Mutations in Troponin that cause HCM, DCM AND RCM: What can we learn about thin filament function?

Willott, R. H., Gomes, A. V., Chang, A. N., Parvatiyar, M. S., Pinto, J. R. & Potter, J. D., May 2010, In : Journal of Molecular and Cellular Cardiology. 48, 5, p. 882-892 11 p.

Research output: Contribution to journalArticle

135 Scopus citations
2011

Sensitive and reproducible intact mass analysis of complex protein mixtures with superficially porous capillary reversed-phase liquid chromatography mass spectrometry

Roth, M. J., Plymire, D. A., Chang, A. N., Kim, J., Maresh, E. M., Larson, S. E. & Patrie, S. M., Dec 15 2011, In : Analytical Chemistry. 83, 24, p. 9586-9592 7 p.

Research output: Contribution to journalArticle

28 Scopus citations
2013

The Effects of Neuregulin on Cardiac Myosin Light Chain Kinase Gene-Ablated Hearts

Chang, A. N., Huang, J., Battiprolu, P. K., Hill, J. A., Kamm, K. E. & Stull, J. T., Jun 11 2013, In : PLoS One. 8, 6, e66720.

Research output: Contribution to journalArticle

9 Scopus citations

Top-down mass spectrometry on tissue extracts and biofluids with isoelectric focusing and superficially porous silica liquid chromatography

Zhang, J., Roth, M. J., Chang, A. N., Plymire, D. A., Corbett, J. R., Greenberg, B. M. & Patrie, S. M., Nov 5 2013, In : Analytical Chemistry. 85, 21, p. 10377-10384 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
2014

Constitutive phosphorylation of myosin phosphatase targeting subunit-1 in smooth muscle

Tsai, M. H., Chang, A. N., Huang, J., He, W., Sweeney, H. L., Zhu, M., Kamm, K. E. & Stull, J. T., Jul 15 2014, In : Journal of Physiology. 592, 14, p. 3031-3051 21 p.

Research output: Contribution to journalArticle

19 Scopus citations

Long term ablation of protein Kinase a (PKA)-mediated cardiac troponin I phosphorylation leads to excitation-contraction uncoupling and diastolic dysfunction in a knock-in mouse model of hypertrophic cardiomyopathy

Dweck, D., Sanchez-Gonzalez, M. A., Chang, A. N., Dulce, R. A., Badger, C. D., Koutnik, A. P., Ruiz, E. L., Griffin, B., Liang, J., Kabbaj, M., Fincham, F. D., Hare, J. M., Michael Overton, J. & Pinto, J. R., Aug 15 2014, In : Journal of Biological Chemistry. 289, 33, p. 23097-23111 15 p.

Research output: Contribution to journalArticle

16 Scopus citations

Recombinant neuregulin 1 does not activate cardiomyocyte DNA synthesis in normal or infarcted adult mice

Reuter, S., Soonpaa, M. H., Firulli, A. B., Chang, A. N. & Field, L. J., Dec 29 2014, In : PLoS One. 9, 12, e115871.

Research output: Contribution to journalArticle

35 Scopus citations

Structural and protein interaction effects of hypertrophic and dilated cardiomyopathic mutations in alpha-tropomyosin

Chang, A. N., Greenfield, N. J., Singh, A., Potter, J. D. & Pinto, J. R., 2014, In : Frontiers in Physiology. 5, DEC, 460.

Research output: Contribution to journalArticle

8 Scopus citations
2015

Constitutive phosphorylation of cardiac myosin regulatory light chain in vivo

Chang, A. N., Battiprolu, P. K., Cowley, P. M., Chen, G., Gerard, R. D., Pinto, J. R., Hill, J. A., Baker, A. J., Kamm, K. E. & Stull, J. T., Apr 24 2015, In : Journal of Biological Chemistry. 290, 17, p. 10703-10716 14 p.

Research output: Contribution to journalArticle

30 Scopus citations

The α<inf>1</inf>A-adrenergic receptor subtype mediates increased contraction of failing right ventricular myocardium

Cowley, P. M., Wang, G., Chang, A. N., Makwana, O., Swigart, P. M., Lovett, D. H., Stull, J. T., Simpson, P. C. & Baker, A. J., Sep 3 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 309, 5, p. H888-H896

Research output: Contribution to journalArticle

12 Scopus citations
2016

Cardiac myosin light chain is phosphorylated by Ca2+/calmodulin-dependent and -independent kinase activities

Chang, A. N., Mahajan, P., Knapp, S., Barton, H., Sweeney, H. L., Kamm, K. E. & Stull, J. T., Jul 5 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 27, p. E3824-E3833

Research output: Contribution to journalArticle

14 Scopus citations

Physiological signalling to myosin phosphatase targeting subunit-1 phosphorylation in ileal smooth muscle

Gao, N., Chang, A. N., He, W., Chen, C. P., Qiao, Y. N., Zhu, M., Kamm, K. E. & Stull, J. T., Jun 15 2016, In : Journal of Physiology. 594, 12, p. 3209-3225 17 p.

Research output: Contribution to journalArticle

13 Scopus citations
7 Scopus citations
2017

Physiological vs. pharmacological signalling to myosin phosphorylation in airway smooth muscle

Gao, N., Tsai, M. H., Chang, A. N., He, W., Chen, C. P., Zhu, M., Kamm, K. E. & Stull, J. T., Oct 1 2017, In : Journal of Physiology. 595, 19, p. 6231-6247 17 p.

Research output: Contribution to journalArticle

7 Scopus citations
2 Scopus citations
2018

Similar biophysical abnormalities in glomeruli and podocytes from two distinct models

Embry, A. E., Liu, Z., Henderson, J. M., Byfield, F. J., Liu, L., Yoon, J., Wu, Z., Cruz, K., Moradi, S., Gillombardo, C. B., Hussain, R. Z., Doelger, R., Stuve, O., Chang, A. N., Janmey, P. A., Bruggeman, L. A. & Miller, R. T., May 1 2018, In : Journal of the American Society of Nephrology. 29, 5, p. 1501-1512 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

The dominant protein phosphatase PP1c isoform in smooth muscle cells, PP1cβ, is essential for smooth muscle contraction

Chang, A. N., Gao, N., Liu, Z., Huang, J., Nairn, A. C., Kamm, K. E. & Stull, J. T., Jan 1 2018, In : Journal of Biological Chemistry. 293, 43, p. 16677-16686 10 p.

Research output: Contribution to journalArticle

1 Scopus citations