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Research Output 1982 2019

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Comment/debate
2019

Author Correction: Drug response in organoids generated from frozen primary tumor tissues (Scientific Reports, (2016), 6, 1, (18889), 10.1038/srep18889)

Walsh, A. J., Cook, R. S., Sanders, M. E., Arteaga, C. L. & Skala, M. C., Dec 1 2019, In : Scientific Reports. 9, 1, 6517.

Research output: Contribution to journalComment/debate

Open Access
Organoids
Pharmaceutical Preparations
Neoplasms
2 Citations (Scopus)

Author Correction: HER kinase inhibition in patients with HER2- and HER3-mutant cancers (Nature, (2018), 554, 7691, (189-194), 10.1038/nature25475)

Hyman, D. M., Piha-Paul, S. A., Won, H., Rodon, J., Saura, C., Shapiro, G. I., Juric, D., Quinn, D. I., Moreno, V., Doger, B., Mayer, I. A., Boni, V., Calvo, E., Loi, S., Lockhart, A. C., Erinjeri, J. P., Scaltriti, M., Ulaner, G. A., Patel, J., Tang, J. & 27 others, Beer, H., Selcuklu, S. D., Hanrahan, A. J., Bouvier, N., Melcer, M., Murali, R., Schram, A. M., Smyth, L. M., Jhaveri, K., Li, B. T., Drilon, A., Harding, J. J., Iyer, G., Taylor, B. S., Berger, M. F., Cutler, R. E., Xu, F., Butturini, A., Eli, L. D., Mann, G., Farrell, C., Lalani, A. S., Bryce, R. P., Arteaga, C. L., Meric-Bernstam, F., Baselga, J. & Solit, D. B., Feb 28 2019, In : Nature. 566, 7745, p. E11-E12

Research output: Contribution to journalComment/debate

Open Access
Phosphotransferases
Neoplasms

Correction: ER+ breast cancers resistant to prolonged neoadjuvant letrozole exhibit an E2F4 transcriptional program sensitive to CDK4/6 inhibitors (Clinical Cancer Research (2018) 24 (2517–29) DOI: 10.1158/1078-0432.CCR-17-2904)

Guerrero-Zotano, A. L., Stricker, T. P., Formisano, L., Hutchinson, K. E., Stover, D. G., Lee, K. M., Schwarz, L. J., Giltnane, J. M., Estrada, M. V., Jansen, V. M., Servetto, A., Gavila, J. J., Perez-Fidalgo, A., Lluch, A., Llombart-Cussac, A., Bayar, M. A., Michiels, S., Andre, F., Arnedos, M., Guillem, V. & 2 others, Ruiz-Simon, A. & Arteaga, C. L., Feb 15 2019, In : Clinical Cancer Research. 25, 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access
letrozole
Disclosure
Emotions
Breast Neoplasms
Research

Correction: Extracellular matrix/integrin signaling promotes resistance to combined inhibition of HER2 and PI3K in HER2 þ breast cancer (Cancer Research (2017) 77 (3280–3292) DOI: 10.1158/0008-5472.CAN-16-2808)

Hanker, A. B., Estrada, M. V., Bianchini, G., Moore, P. D., Zhao, J., Cheng, F., Koch, J. P., Gianni, L., Tyson, D. R., Sánchez, V., Rexer, B. N., Sanders, M. E., Zhao, Z., Stricker, T. P. & Arteaga, C. L., Feb 15 2019, In : Cancer Research. 79, 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Disclosure
Phosphatidylinositol 3-Kinases
Integrins
Extracellular Matrix
Emotions

Correction: 18 F-fluoroestradiol PET/CT measurement of estrogen receptor suppression during a phase I trial of the novel estrogen receptor-targeted therapeutic GDC-0810: Using an imaging biomarker to guide drug dosage in subsequent trials(Clin Cancer Res. (2017) 3:12 (3053-3060) DOI: 10.1158/1078-0432.CCR-16-219)

Wang, Y., Ayres, K. L., Goldman, D. A., Dickler, M. N., Bardia, A., Mayer, I. A., Winer, E., Fredrickson, J., Arteaga, C. L., Baselga, J., Manning, H. C., Mahmood, U. & Ulaner, G. A., Feb 15 2019, In : Clinical Cancer Research. 25, 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Disclosure
Estrogen Receptors
Emotions
Biomarkers
Pharmaceutical Preparations
Open Access
Disclosure
Emotions
Breast Neoplasms
Neoplasms
N-(4-(3-chloro-4-(2-pyridinylmethoxy)anilino)-3-cyano-7-ethoxy-6-quinolyl)-4-(dimethylamino)-2-butenamide

Correction: HER2-overexpressing breast cancers amplify FGFR signaling upon acquisition of resistance to dual therapeutic blockade of HER2(Clin Cancer Res. (2017) 23:15 (4323-4334) DOI: 10.1158/1078-0432.CCR-16-2287)

Hanker, A. B., Garrett, J. T., Valeria Estrada, M., Moore, P. D., Ericsson, P. G., Koch, J. P., Langley, E., Singh, S., Kim, P. S., Frampton, G. M., Sanford, E., Owens, P., Becker, J., Groseclose, M. R., Castellino, S., Joensuu, H., Huober, J., Brase, J. C., Majjaj, S., Brohee, S. & 6 others, Venet, D., Brown, D., Baselga, J., Piccart, M., Sotiriou, C. & Arteaga, C. L., Feb 15 2019, In : Clinical Cancer Research. 25, 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Disclosure
Emotions
Breast Neoplasms
Neoplasms
Therapeutics
Open Access
Disclosure
Emotions
Research
Neoplasms

Correction: Treatment of triple-negative breast cancer with TORC1/2 inhibitors sustains a drug-resistant and Notch-dependent cancer stem cell population (Cancer Research (2016) 76 (440–452) DOI: 10.1158/0008-5472.CAN-15-1640-T)

Bhola, N. E., Jansen, V. M., Koch, J. P., Li, H., Formisano, L., Williams, J. A., Grandis, J. R. & Arteaga, C. L., Feb 15 2019, In : Cancer Research. 79, 4, 1 p.

Research output: Contribution to journalComment/debate

Triple Negative Breast Neoplasms
Neoplastic Stem Cells
Disclosure
Emotions
Research

Correction: Association of FGFR1 with ERA maintains ligand-independent ER transcription and mediates resistance to estrogen deprivation in ER þ breast cancer (Clinical Cancer Research (2019)23 (6138–6150) Doi:10.1158/1078-0432.CCR-17-1232)

Formisano, L., Stauffer, K. M., Young, C. D., Bhola, N. E., Angel, L. G. Z., Jansen, V. M., Estrada, M. M., Hutchinson, K. E., Giltnane, J. M., Schwarz, L. J., Lu, Y., Balko, J. M., Deas, O., Cairo, S., Judde, J. G., Mayer, I. A., Sanders, M., Dugger, T. C., Bianco, R., Stricker, T. & 1 others, Arteaga, C. L., Feb 15 2019, In : Clinical Cancer Research. 25, 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Disclosure
Emotions
Estrogens
Breast Neoplasms
Ligands

Correction: Kinome-wide functional screen identifies role of PLK1 in hormone-independent, ER-positive breast cancer (Cancer Research (2015) 75 (405–414) DOI: 10.1158/0008-5472.CAN-14-2475)

Bhola, N. E., Jansen, V. M., Bafna, S., Giltnane, J. M., Balko, J. M., Estrada, M. V., Meszoely, I., Mayer, I., Abramson, V., Ye, F., Sanders, M., Dugger, T. C., Allen, E. V. & Arteaga, C. L., Feb 15 2019, In : Cancer Research. 79, 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Disclosure
Emotions
Hormones
Breast Neoplasms
Research

Correction: Pik3ca c2 domain deletions hyperactivate phosphoinositide 3-kinase (pi3k), generate oncogene dependence, and are exquisitely sensitive to pi3ka inhibitors(Clin Cancer Res (2018) 24 (1426–35)DOI: 10.1158/1078-0432.CCR-17-2141)

Croessmann, S., Sheehan, J. H., Lee, K. M., Sliwoski, G., He, J., Nagy, R., Riddle, D., Mayer, I. A., Balko, J. M., Lanman, R., Miller, V. A., Cantley, L. C., Meiler, J. & Arteaga, C. L., Feb 15 2019, In : Clinical Cancer Research. 25, 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access
1-Phosphatidylinositol 4-Kinase
Disclosure
Oncogenes
Emotions
Neoplasms

Correction: RAS/MAPK activation is associated with reduced tumor-infiltrating lymphocytes in triple-negative breast cancer: Therapeutic cooperation between MEK and PD-1/PD-L1 immune checkpoint inhibitors(Clin Cancer Res. (2016)22:6 (1499-509) DOI: 10.1158/1078-0432.CCR-15-1125)

Loi, S., Dushyanthen, S., Beavis, P. A., Salgado, R., Denkert, C., Savas, P., Combs, S., Rimm, D. L., Giltnane, J. M., Estrada, M. V., Sanchez, V., Sanders, M. E., Cook, R. S., Pilkinton, M. A., Mallal, S. A., Wang, K., Miller, V. A., Stephens, P. J., Yelensky, R., Doimi, F. D. & 5 others, Gomez, H., Ryzhov, S. V., Darcy, P. K., Arteaga, C. L. & Balko, J. M., Feb 15 2019, In : Clinical Cancer Research. 25, 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Triple Negative Breast Neoplasms
Tumor-Infiltrating Lymphocytes
Mitogen-Activated Protein Kinase Kinases
Disclosure
Emotions

Erratum: Correction: The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer (eLife (2016) 5 PII: e44851)

Joseph, J. D., Darimont, B., Zhou, W., Arrazate, A., Young, A., Ingalla, E., Walter, K., Blake, R. A., Nonomiya, J., Guan, Z., Kategaya, L., Govek, S. P., Lai, A. G., Kahraman, M., Brigham, D., Sensintaffar, J., Lu, N., Shao, G., Qian, J., Grillot, K. & 26 others, Moon, M., Prudente, R., Bischoff, E., Lee, K. J., Bonnefous, C., Douglas, K. L., Julien, J. D., Nagasawa, J. Y., Aparicio, A., Kaufman, J., Haley, B., Giltnane, J. M., Wertz, I. E., Lackner, M. R., Nannini, M. A., Sampath, D., Schwarz, L., Manning, H. C., Tantawy, M. N., Arteaga, C. L., Heyman, R. A., Rix, P. J., Friedman, L., Smith, N. D., Metcalfe, C. & Hager, J. H., Jan 7 2019, In : eLife. 8

Research output: Contribution to journalComment/debate

Estrogen Receptors
Medicine
Breast Neoplasms
3-(4-(2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-en-1-yl)phenyl)acrylic acid

Erratum for the research article: Genomic proling of ER + breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance (Science Translational Medicine DOI: 10.1126/scitranslmed.aai7993)

Giltnane, J. M., Hutchinson, K. E., Stricker, T. P., Formisano, L., Young, C. D., Estrada, M. V., Nixon, M. J., Du, L., Sanchez, V., Ericsson, P. G., Kuba, M. G., Sanders, M. E., Mu, X. J., Van Allen, E. M., Wagle, N., Mayer, I. A., Abramson, V., Gόmez, H., Rizzo, M., Toy, W. & 15 others, Chandarlapaty, S., Mayer, E. L., Christiansen, J., Murphy, D., Fitzgerald, K., Wang, K., Ross, J. S., Miller, V. A., Stephens, P. J., Yelensky, R., Garraway, L., Shyr, Y., Meszoely, I., Balko, J. M. & Arteaga, C. L., Feb 13 2019, In : Science Translational Medicine. 11, 479, eaaw7620.

Research output: Contribution to journalComment/debate

Translational Medical Research
Estrogens
Breast Neoplasms
Research

Erratum for The research article: The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation (Science Translational Medicine DOI: 10.1126/scitranslmed.aal4682)

Kodack, D. P., Askoxylakis, V., Ferraro, G. B., Sheng, Q., Badeaux, M., Goel, S., Qi, X., Shankaraiah, R., Cao, Z. A., Ramjiawan, R. R., Bezwada, D., Patel, B., Song, Y., Costa, C., Naxerova, K., Wong, C. S. F., Kloepper, J., Das, R., Tam, A., Tanboon, J. & 13 others, Duda, D. G., Miller, C. R., Siegel, M. B., Anders, C. K., Sanders, M., Estrada, M. V., Schlegel, R., Arteaga, C. L., Brachtel, E., Huang, A., Fukumura, D., Engelman, J. A. & Jain, R. K., Jan 30 2019, In : Science Translational Medicine. 11, 477, aaw6935.

Research output: Contribution to journalComment/debate

Translational Medical Research
Phosphatidylinositol 3-Kinases
Breast Neoplasms
Brain
Research
2018

Correction: Kinome-wide RNA interference screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition in ER-positive breast cancer (Cancer Research (2017) 77 (2488-2499) DOI: 10.1158/0008-5472)

Jansen, V. M., Bhola, N. E., Bauer, J. A., Formisano, L., Lee, K. M., Hutchinson, K. E., Witkiewicz, A., Moore, P. D., Estrada, M. V., Sánchez, V., Ericsson, P. G., Sanders, M. E., Pohlmann, P. R., Pishvaian, M. J., Riddle, D. A., Dugger, T. C., Wei, W., Knudsen, E. S. & Arteaga, C. L., Feb 15 2018, In : Cancer Research. 79, 4, 1 p.

Research output: Contribution to journalComment/debate

Disclosure
RNA Interference
Emotions
Breast Neoplasms
Research

Correction: Will PI3K pathway inhibitors be effective as single agents in patients with cancer? [Oncotarget. 2, (2011), 1314-1321]doi 10.18632/oncotarget.409

Garrett, J. T., Chakrabarty, A. & Arteaga, C. L., Aug 17 2018, In : Oncotarget. 9, 64, p. 32400 1 p.

Research output: Contribution to journalComment/debate

Proxy
Phosphatidylinositol 3-Kinases
Neoplasms
2013
1 Citation (Scopus)

Mouse models and anti-HER2 therapies

Hanker, A. B., Cook, R. S. & Arteaga, C. L., Nov 1 2013, In : Oncotarget. 4, 11, p. 1866-1867 2 p.

Research output: Contribution to journalComment/debate

Experimental Mammary Neoplasms
ErbB-2 Receptor
Molecular Targeted Therapy
Animal Disease Models
Phenotype
2011
10 Citations (Scopus)

Dead-box or black-box: Is DDX1 a potential biomarker in breast cancer?

Balko, J. M. & Arteaga, C. L., May 1 2011, In : Breast Cancer Research and Treatment. 127, 1, p. 65-67 3 p.

Research output: Contribution to journalComment/debate

DEAD-box RNA Helicases
Survival Analysis
Tumor Biomarkers
Biomarkers
Breast Neoplasms
Phosphatidylinositol 3-Kinases
Breast Neoplasms
Mutation
Neoplasms
2010
14 Citations (Scopus)

Does lapatinib work against HER2-negative breast cancers?

Mayer, I. A. & Arteaga, C. L., Mar 1 2010, In : Clinical Cancer Research. 16, 5, p. 1355-1357 3 p.

Research output: Contribution to journalComment/debate

Estrogen Receptors
Breast Neoplasms
Estrogens
Receptor Cross-Talk
Growth Factor Receptors
2009
33 Citations (Scopus)

Inhibition of PI3K and MEK: It is all about combinations and biomarkers

Rexer, B. N., Ghosh, R. & Arteaga, C. L., Jul 15 2009, In : Clinical Cancer Research. 15, 14, p. 4518-4520 3 p.

Research output: Contribution to journalComment/debate

Phosphatidylinositol 3-Kinase
Mitogen-Activated Protein Kinase Kinases
Biomarkers
PTEN Phosphohydrolase
Breast Neoplasms
1998
5 Citations (Scopus)

Erratum: Growth retardation and tumour inhibition by BRCA1 (Nature Genetics (1996) 12 (pp. 298-302))

Holt, J. T., Thompson, M. E., Szabo, C., Robinson-Benion, C., Arteaga, C. L., King, M. C. & Jensen, R. A., Jan 1 1998, In : Nature Genetics. 19, 1, 1 p.

Research output: Contribution to journalComment/debate

Growth
Neoplasms
1997
Transforming Growth Factor beta1
Biosynthesis
Ligands
Processing
transforming growth factor-beta type II receptor