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Research Output 2004 2019

  • 2395 Citations
  • 15 h-Index
  • 32 Article
  • 3 Conference contribution
2019
2 Citations (Scopus)

Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency

Jakkamsetti, V., Marin-Valencia, I., Ma, Q., Good, L. B., Terrill, T., Rajasekaran, K., Pichumani, K., Khemtong, C., Hooshyar, M. A., Sundarrajan, C., Patel, M. S., Bachoo, R., Malloy, C. R. & Pascual, J. M., Jan 1 2019, In : Science Translational Medicine. 11, 480, aan0457.

Research output: Contribution to journalArticle

Pyruvate Dehydrogenase Complex Deficiency Disease
Citric Acid Cycle
Brain
Glutamic Acid
Pyruvic Acid
1 Citation (Scopus)

Effects of deuteration on transamination and oxidation of hyperpolarized 13 C-Pyruvate in the isolated heart

Funk, A. M., Wen, X., Hever, T., Maptue, N. R., Khemtong, C., Sherry, D. & Malloy, C. R., Apr 1 2019, In : Journal of Magnetic Resonance. 301, p. 102-108 7 p.

Research output: Contribution to journalArticle

pyruvates
Pyruvic Acid
alanine
Oxidation
oxidation
1 Citation (Scopus)
Hydroxybutyrates
Metabolism
Oxidation-Reduction
Tissue
NAD
Open Access
Pyruvate Dehydrogenase Complex
Pyruvic Acid
Knockout Mice
Magnetic Resonance Spectroscopy
Liver
2018
3 Citations (Scopus)

A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity

Wu, C. Y., Satapati, S., Gui, W., Max Wynn, R., Sharma, G., Lou, M., Qi, X., Burgess, S. C., Malloy, C., Khemtong, C., Dean Sherry, A., Chuang, D. T. & Merritt, M. E., Jan 1 2018, In : Journal of Biological Chemistry. 293, 25, p. 9604-9613 10 p.

Research output: Contribution to journalArticle

Pyruvate Dehydrogenase Complex
Obese Mice
Protein-Serine-Threonine Kinases
Protein Kinase Inhibitors
Pyruvic Acid
2 Citations (Scopus)

Esterase-Catalyzed Production of Hyperpolarized 13C-Enriched Carbon Dioxide in Tissues for Measuring pH

Maptue, N., Jiang, W., Harrison, C., Funk, A. M., Sharma, G., Malloy, C. R., Sherry, D. & Khemtong, C., Nov 26 2018, In : ACS Sensors. 3, 11, p. 2232-2236 5 p.

Research output: Contribution to journalArticle

Carbonates
Esterases
Carbon Dioxide
carbon dioxide
carbonates
12 Citations (Scopus)

MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation

Makarewich, C. A., Baskin, K. K., Munir, A. Z., Bezprozvannaya, S., Sharma, G., Khemtong, C., Shah, A. M., McAnally, J. R., Malloy, C. R., Szweda, L. I., Bassel-Duby, R. & Olson, E. N., Jun 26 2018, In : Cell Reports. 23, 13, p. 3701-3709 9 p.

Research output: Contribution to journalArticle

Mitochondrial Membranes
Fatty Acids
RNA
Muscles
Oxidation

Probing carbohydrate metabolism using hyperpolarized 13C-labeled molecules

Singh, J., Suh, E. H., Sharma, G., Khemtong, C., Sherry, D. & Kovacs, Z., Jan 1 2018, (Accepted/In press) In : NMR in Biomedicine. e4018.

Research output: Contribution to journalArticle

Carbohydrate Metabolism
Glycolysis
Molecules
Pyruvic Acid
Glucose
1 Citation (Scopus)

Rational Design of [13C,D14]Tert-butylbenzene as a Scaffold Structure for Designing Long-lived Hyperpolarized 13C Probes

Imakura, Y., Nonaka, H., Takakusagi, Y., Ichikawa, K., Maptue, N. R., Funk, A. M., Khemtong, C. & Sando, S., Feb 2 2018, In : Chemistry - An Asian Journal. 13, 3, p. 280-283 4 p.

Research output: Contribution to journalArticle

Spin-lattice relaxation
Scaffolds
Hot Temperature
Nuclear magnetic resonance
Water
9 Citations (Scopus)

Targeting hepatic pyruvate dehydrogenase kinases restores insulin signaling and mitigates ChREBP-mediated lipogenesis in diet-induced obese mice

Wu, C. Y., Tso, S. C., Chuang, J. L., Gui, W. J., Lou, M., Sharma, G., Khemtong, C., Qi, X., Wynn, R. M. & Chuang, D. T., Jan 1 2018, (Accepted/In press) In : Molecular Metabolism.

Research output: Contribution to journalArticle

Obese Mice
Lipogenesis
Carrier Proteins
Knockout Mice
Carbohydrates
2017
13 Citations (Scopus)

Influence of Dy3+ and Tb3+ doping on 13C dynamic nuclear polarization

Niedbalski, P., Parish, C., Kiswandhi, A., Fidelino, L., Khemtong, C., Hayati, Z., Song, L., Martins, A., Sherry, A. D. & Lumata, L., Jan 7 2017, In : Journal of Chemical Physics. 146, 1, 014303.

Research output: Contribution to journalArticle

Doping (additives)
Polarization
polarization
Lanthanoid Series Elements
dissolving
7 Citations (Scopus)

In vivo assessment of intracellular redox state in rat liver using hyperpolarized [1-13C]Alanine

Park, J. M., Khemtong, C., Liu, S. C., Hurd, R. E. & Spielman, D. M., 2017, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Alanine
Oxidation-Reduction
Ethanol
Pyruvic Acid
Lactic Acid

Synthesis of PAA-PAMPS-PNaSS terpolymers as ultraviolet-tagged scale inhibitor for industrial water cooling system

Jitreewas, P., Saengvattanarat, S., Tansiri, P., Pranee, S., Chuayprakong, S., Khemtong, C. & Seeyangnok, S., Jan 1 2017, Green Convergence on Materials Frontiers - 11th Pure and Applied Chemistry International Conference, PACCON 2017. Trans Tech Publications Ltd, Vol. 757 KEM. p. 68-72 5 p. (Key Engineering Materials; vol. 757 KEM).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Water cooling systems
Terpolymers
carbopol 940
Polymers
Acrylics
3 Citations (Scopus)

The rate of lactate production from glucose in hearts is not altered by per-deuteration of glucose

Funk, A. M., Anderson, B. L., Wen, X., Hever, T., Khemtong, C., Kovacs, Z., Sherry, A. D. & Malloy, C. R., Nov 1 2017, In : Journal of Magnetic Resonance. 284, p. 86-93 8 p.

Research output: Contribution to journalArticle

lactates
glucose
Lactic Acid
Glucose
alanine
2016
14 Citations (Scopus)

Impact of Ho3+-doping on 13C dynamic nuclear polarization using trityl OX063 free radical

Kiswandhi, A., Niedbalski, P., Parish, C., Kaur, P., Martins, A., Fidelino, L., Khemtong, C., Song, L., Sherry, A. D. & Lumata, L., 2016, In : Physical Chemistry Chemical Physics. 18, 31, p. 21351-21359 9 p.

Research output: Contribution to journalArticle

free radicals
Free Radicals
Doping (additives)
Polarization
polarization
2015
23 Citations (Scopus)

Hyperpolarized <sup>13</sup>C NMR detects rapid drug-induced changes in cardiac metabolism

Khemtong, C., Carpenter, N. R., Lumata, L. L., Merritt, M. E., Moreno, K. X., Kovacs, Z., Malloy, C. R. & Sherry, A. D., Aug 1 2015, In : Magnetic Resonance in Medicine. 74, 2, p. 312-319 8 p.

Research output: Contribution to journalArticle

Pyruvic Acid
Isoproterenol
Lactic Acid
Pharmaceutical Preparations
Glycogen
56 Citations (Scopus)

Hyperpolarized 15 N-pyridine Derivatives as pH-Sensitive MRI Agents

Jiang, W., Lumata, L., Chen, W., Zhang, S., Kovacs, Z., Sherry, A. D. & Khemtong, C., Mar 16 2015, In : Scientific Reports. 5, 9104.

Research output: Contribution to journalArticle

pyridine
2012
33 Citations (Scopus)

The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy

Lumata, L., Merritt, M., Khemtong, C., Ratnakar, S. J., Van Tol, J., Yu, L., Song, L. & Kovacs, Z., Dec 21 2012, In : RSC Advances. 2, 33, p. 12812-12817 6 p.

Research output: Contribution to journalArticle

Nuclear magnetic resonance spectroscopy
Polarization
Dissolution
Free radicals
Paramagnetic resonance
2011
371 Citations (Scopus)

Nanonization strategies for poorly water-soluble drugs

Chen, H., Khemtong, C., Yang, X., Chang, X. & Gao, J., Apr 2011, In : Drug Discovery Today. 16, 7-8, p. 354-360 7 p.

Research output: Contribution to journalArticle

Water
Pharmaceutical Preparations
Solubility
Micelles
Nanoparticles
12 Citations (Scopus)

Off-resonance saturation MRI of superparamagnetic nanoprobes: Theoretical models and experimental validations

Khemtong, C., Togao, O., Ren, J., Kessinger, C. W., Takahashi, M., Sherry, A. D. & Gao, J., Mar 2011, In : Journal of Magnetic Resonance. 209, 1, p. 53-60 8 p.

Research output: Contribution to journalArticle

Nanoprobes
Micelles
Magnetic resonance
magnetic resonance
micelles
2010
24 Citations (Scopus)

In vivo angiogenesis imaging of solid tumors by αvβ 3-targeted, dual-modality micellar nanoprobes

Kessinger, C. W., Khemtong, C., Togao, O., Takahashi, M., Sumer, B. D. & Gao, J., Aug 2010, In : Experimental Biology and Medicine. 235, 8, p. 957-965 9 p.

Research output: Contribution to journalArticle

Nanoprobes
Micelles
Tumors
Imaging techniques
Neoplasms
134 Citations (Scopus)

MRI-visible micellar nanomedicine for targeted drug delivery to lung cancer cells

Guthi, J. S., Yang, S. G., Huang, G., Li, S., Khemtong, C., Kessinger, C. W., Peyton, M., Minna, J. D., Brown, K. C. & Gao, J., Feb 1 2010, In : Molecular Pharmaceutics. 7, 1, p. 32-40 9 p.

Research output: Contribution to journalArticle

Nanomedicine
Micelles
Lung Neoplasms
Pharmaceutical Preparations
Peptides
38 Citations (Scopus)

Polymeric micelle nanoparticles for photodynamic treatment of head and neck cancer cells

Cohen, E. M., Ding, H., Kessinger, C. W., Khemtong, C., Gao, J. & Sumer, B. D., Jul 2010, In : Otolaryngology - Head and Neck Surgery. 143, 1, p. 109-115 7 p.

Research output: Contribution to journalArticle

Micelles
Head and Neck Neoplasms
Nanoparticles
Photochemotherapy
Therapeutics
83 Citations (Scopus)

β-lapachone micellar nanotherapeutics for non-small cell lung cancer therapy

Blanco, E., Bey, E. A., Khemtong, C., Yang, S. G., Setti-Guthi, J., Chen, H., Kessinger, C. W., Carnevale, K. A., Bornmann, W. G., Boothman, D. A. & Gao, J., May 15 2010, In : Cancer Research. 70, 10, p. 3896-3904 9 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Neoplasms
Micelles
Therapeutics
Pharmacokinetics
2009
71 Citations (Scopus)

A novel strategy for surface modification of superparamagnetic iron oxide nanoparticles for lung cancer imaging

Huang, G., Zhang, C., Li, S., Khemtong, C., Yang, S. G., Tian, R., Minna, J. D., Brown, K. C. & Gao, J., 2009, In : Journal of Materials Chemistry. 19, 35, p. 6367-6372 6 p.

Research output: Contribution to journalArticle

Iron oxides
Surface treatment
Nanoparticles
Imaging techniques
Nanoprobes
79 Citations (Scopus)

In vivo off-resonance saturation magnetic resonance imaging of α vβ 3-targeted superparamagnetic nanoparticles

Khemtong, C., Kessinger, C. W., Ren, J., Bey, E. A., Yang, S. G., Guthi, J. S., Boothman, D. A., Sherry, A. D. & Gao, J., Feb 15 2009, In : Cancer Research. 69, 4, p. 1651-1658 8 p.

Research output: Contribution to journalArticle

Nanoparticles
Micelles
Magnetic Resonance Imaging
Molecular Imaging
Neoplasms
3 Citations (Scopus)

Off-resonance saturation magnetic resonance imaging of superparamagnetic polymeric micelles

Khemtong, C., Kessinger, C. W., Togao, O., Ren, J., Takahashi, M., Sherry, A. D. & Gao, J., 2009, Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. p. 4095-4097 3 p. 5334550

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Micelles
Magnetic resonance
Magnetic Resonance Imaging
Imaging techniques
Magnetic resonance imaging
146 Citations (Scopus)

Polymeric nanomedicine for cancer MR imaging and drug delivery

Khemtong, C., Kessinger, C. W. & Gao, J., 2009, In : Chemical Communications. 24, p. 3497-3510 14 p.

Research output: Contribution to journalArticle

Medical nanotechnology
Drug delivery
Nanocomposites
Polymers
Imaging techniques
2008
113 Citations (Scopus)

Zinc ferrite nanoparticles as MRI contrast agents

Bárcena, C., Sra, A. K., Chaubey, G. S., Khemtong, C., Liu, J. P. & Gao, J., 2008, In : Chemical Communications. 19, p. 2224-2226 3 p.

Research output: Contribution to journalArticle

Micelles
Magnetic resonance imaging
Contrast Media
Ferrite
Zinc
2007

Zinc superparamagnetic iron oxide nanoparticles for use as MRI contrast agents

Barcena, C., Khemtong, C., Chaubey, G. S., Kessinger, C. W., Liu, J. P. & Gao, J., 2007, Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007. p. 49-50 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zinc oxide
Magnetic resonance imaging
Contrast Media
Nanoparticles
ferric oxide
2006
1026 Citations (Scopus)

Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems

Nasongkla, N., Bey, E., Ren, J., Ai, H., Khemtong, C., Guthi, J. S., Chin, S. F., Sherry, A. D., Boothman, D. A. & Gao, J., Nov 2006, In : Nano Letters. 6, 11, p. 2427-2430 4 p.

Research output: Contribution to journalArticle

Micelles
Magnetic resonance
magnetic resonance
delivery
micelles
2005
5 Citations (Scopus)

Formation of an inclusion complex of a new transition metal ligand in β-cyclodextrin

Khemtong, C., Banerjee, D., Liu, Y., El Khoury, J. M., Rinaldi, P. L. & Hu, J., Jun 2005, In : Supramolecular Chemistry. 17, 4, p. 335-341 7 p.

Research output: Contribution to journalArticle

Cyclodextrins
Transition metals
Nuclear magnetic resonance
Carboxylic Acids
Ligands
1 Citation (Scopus)

Preparation of 7-azidocarbonyl-2,4,9-trithiaadamantane by a new thioacetal crown synthetic method

Khemtong, C. & Hu, J., Apr 2005, In : Journal of Sulfur Chemistry. 26, 2, p. 105-109 5 p.

Research output: Contribution to journalArticle

Self assembled monolayers
Gold
2004
24 Citations (Scopus)

Photochemical patterning of a self-assembled monolayer of 7-diazomethylcarbonyl-2,4,9-trithiaadmantane on gold films via wolff rearrangement

Hu, J., Liu, Y., Khemtong, C., El Khoury, J. M., McAfoos, T. J. & Taschner, I. S., Jun 8 2004, In : Langmuir. 20, 12, p. 4933-4938 6 p.

Research output: Contribution to journalArticle

Self assembled monolayers
Gold
gold
Anchors
reactivity
85 Citations (Scopus)
Palladium
Catalyst activity
Ligands
Microwaves
Nanoparticles