• 3460 Citations
  • 35 h-Index
1979 …2019
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Research Output 1979 2019

  • 3460 Citations
  • 35 h-Index
  • 101 Article
  • 2 Chapter
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Article
2019
Acute Kidney Injury
Sepsis
Inflammation
Kidney
Lipopolysaccharides
2016
15 Citations (Scopus)
Graft Rejection
Tacrolimus
Steroids
Tissue Donors
Kidney
7 Citations (Scopus)

Biochemical and cellular determinants of renal glomerular elasticity

Embry, A. E., Mohammadi, H., Niu, X., Liu, L., Moe, B., Miller-Little, W. A., Lu, C. Y., Bruggeman, L. A., McCulloch, C. A., Janmey, P. A. & Miller, R. T., Dec 1 2016, In : PLoS One. 11, 12, e0167924.

Research output: Contribution to journalArticle

Podocytes
Elasticity
elasticity (mechanics)
actin
Actins
2015
27 Citations (Scopus)

Induction therapies in live donor kidney transplantation on tacrolimus and mycophenolate with or without steroid maintenance

Tanriover, B., Zhang, S., MacConmara, M., Gao, A., Sandikci, B., Ayvaci, M. U. S., Mete, M., Tsapepas, D., Rajora, N., Mohan, P., Lakhia, R., Lu, C. Y. & Vazquez, M., 2015, In : Clinical Journal of the American Society of Nephrology. 10, 6, p. 1041-1049 9 p.

Research output: Contribution to journalArticle

Tacrolimus
Kidney Transplantation
Interleukin-2
Steroids
Maintenance
2 Citations (Scopus)

Management of steroid-resistant late acute cellular rejection following face transplantation: A case report

Janis, J. E., MacKenzie, K. D., Wright, S. E., Pomahac, B., Lu, C., Susa, J., Wada, S., Vazquez, M. A., Chong, T. & Tullius, S. G., Jan 1 2015, In : Transplantation Proceedings. 47, 1, p. 223-225 3 p.

Research output: Contribution to journalArticle

Facial Transplantation
Steroids
Transplants
NF-E2-Related Factor 2
Regulatory T-Lymphocytes
Acute Kidney Injury
Oxidative Stress
Kelch-Like ECH-Associated Protein 1
2014
5 Citations (Scopus)
NAD
Cisplatin
Inflammation
Wounds and Injuries
Acute Kidney Injury
2013
2 Citations (Scopus)

Deficits in serum amyloid A contribute to increased neonatal mortality during murine listeriosis

Seth Hawkins, J., Wu, Q., Wang, Y. & Lu, C. Y., Dec 2013, In : Pediatric Research. 74, 6, p. 668-674 7 p.

Research output: Contribution to journalArticle

Serum Amyloid A Protein
Listeriosis
Infant Mortality
Real-Time Polymerase Chain Reaction
Listeria
14 Citations (Scopus)

Reactive oxygen species and IRF1 stimulate IFNα production by proximal tubules during ischemic AKI

Winterberg, P. D., Wang, Y., Lin, K. M., Hartono, J. R., Nagami, G. T., Zhou, X. J., Shelton, J. M., Richardson, J. A. & Lu, C. Y., Jul 15 2013, In : American Journal of Physiology - Renal Physiology. 305, 2

Research output: Contribution to journalArticle

Interferon Regulatory Factor-1
Acute Kidney Injury
Interferons
Reactive Oxygen Species
Kidney
2012
19 Citations (Scopus)

Acute kidney injury: A conspiracy of toll-like receptor 4 on endothelia, leukocytes, and tubules

Lu, C. Y., Winterberg, P. D., Chen, J. & Hartono, J. R., Oct 2012, In : Pediatric Nephrology. 27, 10, p. 1847-1854 8 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Acute Kidney Injury
Endothelium
Leukocytes
HMGB1 Protein
9 Citations (Scopus)

Acute kidney injury: The beginning of the end of the dark ages

Winterberg, P. D. & Lu, C. Y., Oct 2012, In : American Journal of the Medical Sciences. 344, 4, p. 318-325 8 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Mortality
Chronic Renal Insufficiency
Early Diagnosis
Creatinine
29 Citations (Scopus)

Endothelial pentraxin 3 contributes to murine ischemic acute kidney injury

Chen, J., Matzuk, M. M., Zhou, X. J. & Lu, C. Y., Dec 1 2012, In : Kidney International. 82, 11, p. 1195-1207 13 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Toll-Like Receptor 4
Kidney
Endothelial Cells
Knockout Mice
2011
110 Citations (Scopus)

Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1

Wu, Q. Q., Wang, Y., Senitko, M., Meyer, C., Wigley, W. C., Ferguson, D. A., Grossman, E., Chen, J., Zhou, X. J., Hartono, J., Winterberg, P., Chen, B., Agarwal, A. & Lu, C. Y., May 2011, In : American Journal of Physiology - Renal Physiology. 300, 5, p. 1180-1192 13 p.

Research output: Contribution to journalArticle

NF-E2-Related Factor 2
Peroxisome Proliferator-Activated Receptors
Heme Oxygenase-1
Acute Kidney Injury
Gene Expression
39 Citations (Scopus)

Early interleukin 6 production by leukocytes during ischemic acute kidney injury is regulated by TLR4

Chen, J., Hartono, J. R., John, R., Bennett, M., Zhou, X. J., Wang, Y., Wu, Q., Winterberg, P. D., Nagami, G. T. & Lu, C. Y., Sep 1 2011, In : Kidney International. 80, 5, p. 504-515 12 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Acute Kidney Injury
Interleukin-6
Leukocytes
Kidney
92 Citations (Scopus)

Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury

Chen, J., John, R., Richardson, J. A., Shelton, J. M., Zhou, X. J., Wang, Y., Wu, Q. Q., Hartono, J. R., Winterberg, P. D. & Lu, C. Y., Feb 2011, In : Kidney International. 79, 3, p. 288-299 12 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Acute Kidney Injury
Endothelial Cells
Knockout Mice
Reperfusion
2010
1 Citation (Scopus)

Letter to the editor murine fetoplacental infection models

Redline, R. W., Han, Y. W. & Lu, C. Y., Nov 2010, In : Infection and Immunity. 78, 11, p. 4965 1 p.

Research output: Contribution to journalArticle

Infection
2009

Erratum: Essential and unique roles of PIP5Kand -α in Fc receptor-mediated phagocytosis (The Journal of General Physiology (February 23, 2009) Vol. 133: No. 3 (i3) 10.1085/JGP1333OIA3)

Mao, Y. S., Yamaga, M., Zhu, X., Wei, Y., Sun, H. Q., Wang, J., Yun, M., Wang, Y., Paolo, G. D., Bennett, M., Mellman, I., Abrams, C. S., Camilli, P. D., Lu, C. Y. & Yin, H. L., Mar 2009, In : Journal of General Physiology. 133, 3, p. 345-347 3 p.

Research output: Contribution to journalArticle

Phagocytosis
Fc(alpha) receptor
73 Citations (Scopus)

Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis.

Mao, Y. S., Yamaga, M., Zhu, X., Wei, Y., Sun, H. Q., Wang, J., Yun, M., Wang, Y., Di Paolo, G., Bennett, M., Mellman, I., Abrams, C. S., De Camilli, P., Lu, C. Y. & Yin, H. L., Jan 26 2009, In : The Journal of cell biology. 184, 2, p. 281-296 16 p.

Research output: Contribution to journalArticle

Actin Cytoskeleton
Phagocytosis
Eating
Wiskott-Aldrich Syndrome Protein
Macrophages
4 Citations (Scopus)

Inferior vena cava (IVC) filter thrombosis in a renal transplant recipient

Senitko, M., Sims, R., Dolmatch, B., Vazquez, M. A. & Lu, C. Y., 2009, In : Clinical Nephrology. 71, 4, p. 456-459 4 p.

Research output: Contribution to journalArticle

Vena Cava Filters
Allografts
Thrombosis
Kidney
Renal Veins
36 Citations (Scopus)

IRF-1 promotes inflammation early after ischemic acute kidney injury

Wang, Y., John, R., Chen, J., Richardson, J. A., Shelton, J. M., Bennett, M., Zhou, X. J., Nagami, G. T., Zhang, Y., Qing, Q. W. & Lu, C. Y., Jul 2009, In : Journal of the American Society of Nephrology. 20, 7, p. 1544-1555 12 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Inflammation
Kidney
Wounds and Injuries
Reactive Oxygen Species
29 Citations (Scopus)

Renal transplantation in the elderly

Saxena, R., Yu, X., Giraldo, M., Arenas, J., Vazquez, M., Lu, C. Y., Vaziri, N. D., Silva, F. G. & Zhou, X. J., Mar 2009, In : International Urology and Nephrology. 41, 1, p. 195-210 16 p.

Research output: Contribution to journalArticle

Kidney Transplantation
Tissue Donors
Immunosuppressive Agents
Transplants
Kidney
41 Citations (Scopus)

Role of immunoglobulin (Ig)-G and IgM antibodies against donor human leukocyte antigens in organ transplant recipients

Stastny, P., Ring, S., Lu, C., Arenas, J., Han, M. & Lavingia, B., Aug 2009, In : Human Immunology. 70, 8, p. 600-604 5 p.

Research output: Contribution to journalArticle

HLA Antigens
Immunoglobulin M
Immunoglobulin G
Transplants
Antibodies
2 Citations (Scopus)
HLA Antigens
Kidney Transplantation
Anti-Idiotypic Antibodies
Tissue Donors
Antibodies
2007
45 Citations (Scopus)

The inflammatory response to ischemic acute kidney injury: A result of the 'right stuff' in the 'wrong place'?

Lu, C. Y., Hartono, J., Senitko, M. & Chen, J., Mar 2007, In : Current Opinion in Nephrology and Hypertension. 16, 2, p. 83-89 7 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Inflammation
Wounds and Injuries
HMGB1 Protein
Poly(ADP-ribose) Polymerases
2006
5 Citations (Scopus)

Impact of bile duct obstruction on hepatic E. coli infection: Role of IL-10

Jeyarajah, D. R., Kielar, M. L., Saboorian, H., Karimi, P., Frantz, N. & Lu, C. Y., 2006, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 291, 1

Research output: Contribution to journalArticle

Escherichia coli Infections
Cholestasis
Interleukin-10
Liver
Bile Ducts
2005
163 Citations (Scopus)

Maladaptive role of IL-6 in ischemic acute renal failure

Kielar, M. L., John, R., Bennett, M., Richardson, J. A., Shelton, J. M., Chen, L., Jeyarajah, D. R., Zhou, X. J., Zhou, H., Chiquett, B., Nagami, G. T. & Lu, C. Y., 2005, In : Journal of the American Society of Nephrology. 16, 11, p. 3315-3325 11 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Interleukin-6
Kidney
Macrophages
Reperfusion
19 Citations (Scopus)

The lipopolysaccharide-triggered mesangial transcriptome: Evaluating the role of interferon regulatory factor-1

Fu, Y., Xie, C., Yan, M., Li, Q., Joh, J. W., Lu, C. & Mohan, C., Apr 2005, In : Kidney International. 67, 4, p. 1350-1361 12 p.

Research output: Contribution to journalArticle

Interferon Regulatory Factor-1
Mesangial Cells
Transcriptome
Lipopolysaccharides
Granulocyte-Macrophage Colony-Stimulating Factor
2004
112 Citations (Scopus)

Essential Role of STAT3 in Body Weight and Glucose Homeostasis

Cui, Y., Huang, L., Elefteriou, F., Yang, G., Shelton, J. M., Giles, J. E., Oz, O. K., Pourbahrami, T., Lu, C. Y. H., Richardson, J. A., Karsenty, G. & Li, C., Jan 2004, In : Molecular and Cellular Biology. 24, 1, p. 258-269 12 p.

Research output: Contribution to journalArticle

Homeostasis
Body Weight
Glucose
Leptin
Weaning
39 Citations (Scopus)

Ischemia-reperfusion induces G-CSF gene expression by renal medullary thick ascending limb cells in vivo and in vitro

Zhang, Y., Woodward, V. K., Shelton, J. M., Richardson, J. A., Zhou, X. J., Link, D., Kielar, M. L., Jeyarajah, D. R. & Lu, C. Y., Jun 2004, In : American Journal of Physiology - Renal Physiology. 286, 6 55-6

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
Reperfusion
Ischemia
Extremities
Kidney
2003
8 Citations (Scopus)

Acute bile duct ligation ameliorates ischemic renal failure

Jeyarajah, D. R., Kielar, M. L., Zhou, X. J., Zhang, Y. & Lu, C. Y., 2003, In : Nephron. 95, 2

Research output: Contribution to journalArticle

Bile Ducts
Acute Kidney Injury
Renal Insufficiency
Ligation
Kidney
52 Citations (Scopus)
Docosahexaenoic Acids
Nitric Oxide Synthase Type II
Acute Kidney Injury
Reperfusion
Creatinine
9 Citations (Scopus)

Fas deficiency exacerbates cerulein-induced pancreatitis

Jeyarajah, D. R., Kielar, M., Gokaslan, S. T., Lindberg, G. & Lu, C. Y., Nov 2003, In : Journal of Investigative Surgery. 16, 6, p. 325-333 9 p.

Research output: Contribution to journalArticle

Ceruletide
Pancreatitis
Necrosis
Amylases
Edema
2 Citations (Scopus)

Infection by gram-negative organisms via the biliary route results in greater mortality than portal venous infection

Jeyarajah, D. R., Kielar, M. L., Frantz, N., Lindberg, G. & Lu, C. Y., Jul 2003, In : Clinical and Diagnostic Laboratory Immunology. 10, 4, p. 664-669 6 p.

Research output: Contribution to journalArticle

Portal Vein
Bile Ducts
Ducts
Mortality
Liver
2002

BK nephropathy: Clinical Decision making in the face of uncertainty

Lu, C. Y., Dec 2002, In : Graft. 5, SUPPL.

Research output: Contribution to journalArticle

Uncertainty
Clinical Decision-Making
37 Citations (Scopus)

Pancreas after kidney transplantation

Hariharan, S., Pirsch, J. D., Lu, C. Y., Chan, L., Pesavento, T. E., Alexander, S., Bumgardner, G. L., Baasadona, G., Hricik, D. E., Pescovitz, M. D., Rubin, N. T. & Stratta, R. J., 2002, In : Journal of the American Society of Nephrology. 13, 4, p. 1109-1118 10 p.

Research output: Contribution to journalArticle

Pancreas Transplantation
Kidney Transplantation
Immunosuppression
Patient Selection
Pancreas
39 Citations (Scopus)

The regulation of ischemic acute renal failure by extrarenal organs

Kielar, M. L., Jeyarajah, D. R. & Lu, C. Y., 2002, In : Current Opinion in Nephrology and Hypertension. 11, 4, p. 451-457 7 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Kidney
Interleukin-6
Ischemia
Interleukin-10
2001
128 Citations (Scopus)

Epitope mapping of antibodies to the C-terminal region of the integrin β2 subunit reveals regions that become exposed upon receptor activation

Lu, C., Ferzly, M., Takagi, J. & Springer, T. A., May 1 2001, In : Journal of Immunology. 166, 9, p. 5629-5637 9 p.

Research output: Contribution to journalArticle

Epitope Mapping
Integrins
Lymphocyte Function-Associated Antigen-1
Cysteine
Epitopes
2000
18 Citations (Scopus)

Docosahexaenoic acid decreases IRF-1 MRNA and thus inhibits activation of both the IRF-E and NFκd response elements of the iNOS promoter

Kielar, M. L., Jeyarajah, D. R., Penfield, J. G. & Lu, C. Y., May 27 2000, In : Transplantation. 69, 10, p. 2131-2137 7 p.

Research output: Contribution to journalArticle

Docosahexaenoic Acids
Response Elements
Nitric Oxide Synthase Type II
Nuclear Proteins
Lipopolysaccharides
22 Citations (Scopus)
Isoantigens
Nephrons
Financial Management
Kidney Transplantation
Kidney
15 Citations (Scopus)

Nitric oxide inhibits IFNγ-induced increases in CIITA mRNA abundance and activation of CIITA dependent genesclass II MHC, Ii and H-2M

Kielar, M. L., Sicher, S. C., Penfield, J. G., Jeyarajah, D. R. & Lu, C. Y., 2000, In : Inflammation. 24, 5, p. 431-445 15 p.

Research output: Contribution to journalArticle

Nitric Oxide
Messenger RNA
Macrophages
MHC Class II Genes
Antigen Presentation
1999
18 Citations (Scopus)

Docosahexaenoic acid, a component of fish oil, inhibits nitric oxide production in vitro

Jeyarajah, D. R., Kielar, M., Penfield, J. & Lu, C. Y., May 15 1999, In : Journal of Surgical Research. 83, 2, p. 147-150 4 p.

Research output: Contribution to journalArticle

Docosahexaenoic Acids
Fish Oils
Nitric Oxide
Autoimmune Diseases
Macrophages
120 Citations (Scopus)

Hypothesis: Is renal allograft rejection initiated by the response to injury sustained during the transplant process

Lu, C. Y., Penfield, J. G., Kielar, M. L., Vazquez, M. A. & Jeyarajah, D. R., 1999, In : Kidney International. 55, 6, p. 2157-2168 12 p.

Research output: Contribution to journalArticle

Allografts
Transplants
Kidney
Wounds and Injuries
Brain Death
3 Citations (Scopus)

Management of the cadaveric donor of a renal transplant: More than optimizing renal perfusion?

Lu, C. Y., 1999, In : Kidney International. 56, 2, p. 756-757 2 p.

Research output: Contribution to journalArticle

Catecholamines
Perfusion
Transplants
Kidney
25 Citations (Scopus)

Syngeneic renal transplantation increases the number of renal dendritic cells in the rat

Penfield, J. G., Dawidson, I. A., Ar'Rajab, A., Kielar, M. A., Jeyarajah, D. R. & Lu, C. Y., Dec 1999, In : Transplant Immunology. 7, 4, p. 197-200 4 p.

Research output: Contribution to journalArticle

Isogeneic Transplantation
Kidney Transplantation
Dendritic Cells
Transplants
Kidney
63 Citations (Scopus)

Transplant surgery injury recruits recipient MHC class II-positive leukocytes into the kidney

Penfield, J. G., Wang, Y., Li, S., Kielar, M. A., Sicher, S. C., Rouan Jeyarajah, D. & Lu, C. Y., 1999, In : Kidney International. 56, 5, p. 1759-1769 11 p.

Research output: Contribution to journalArticle

Major Histocompatibility Complex
Leukocytes
Transplants
Kidney
Dendritic Cells
1998
19 Citations (Scopus)
Docosahexaenoic Acids
Listeria monocytogenes
Interferons
Lipopolysaccharides
Nitric Oxide

Renal immunology and pathology.

Lu, C. Y. & Salant, D. J., May 1998, In : Current Opinion in Nephrology and Hypertension. 7, 3, p. 279-280 2 p.

Research output: Contribution to journalArticle

Pancreas Transplantation
Nephritis
Kidney Diseases
Allergy and Immunology
Chemokines
1997

Inhibition of macrophage iNOS gene activation in the murine fetus, neonate, and placenta by docosahexaenoic acid (DHA)

Lu, C. Y., Kielar, M. L., Penfield, J. G., Sicher, S. C., Che, L. & Wall, A., 1997, In : Journal of Reproductive Immunology. 34, 1, p. 84 1 p.

Research output: Contribution to journalArticle

Docosahexaenoic Acids
Placenta
Transcriptional Activation
Fetus
Macrophages

Renal immunology and pathology

Lu, C. & Salant, D., 1997, In : Current Opinion in Nephrology and Hypertension. 6, 3, p. 257-258 2 p.

Research output: Contribution to journalArticle

Allergy and Immunology
Pathology
Kidney
1996
4 Citations (Scopus)

Differential regulation of Ia expression and antigen presentation by listeriolysin-producing versus non-producing strains of Listeria monocytogenes

Vazquez, M. A., Sicher, S. C., Proctor, M. L., Crowley, J. C. & Lu, C. Y., May 1996, In : Journal of Leukocyte Biology. 59, 5, p. 683-690 8 p.

Research output: Contribution to journalArticle

Histocompatibility Antigens Class II
Antigen Presentation
Listeria monocytogenes
Listeria
Macrophages