Daniel Nussenzveig

  • 2215 Citations
  • 22 h-Index
1987 …2019
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Research Output 1987 2019

  • 2215 Citations
  • 22 h-Index
  • 35 Article
2019
3 Citations (Scopus)

Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination

Liu, Z., Yan, M., Liang, Y., Liu, M., Zhang, K., Shao, D., Jiang, R., Li, L., Wang, C., Nussenzveig, D., Zhang, K., Chen, S., Zhong, C., Mo, W., Fontoura, B. M. & Zhang, L., May 8 2019, In : Neuron. 102, 3, p. 587-601.e7

Research output: Contribution to journalArticle

Nuclear Pore Complex Proteins
Oligodendroglia
Stem Cells
Wounds and Injuries
Myelin Sheath
2015
6 Citations (Scopus)

Sec13 Regulates Expression of Specific Immune Factors Involved in Inflammation In Vivo

Moreira, T. G., Zhang, L., Shaulov, L., Harel, A., Kuss, S. K., Williams, J., Shelton, J., Somatilaka, B., Seemann, J., Yang, J., Sakthivel, R., Nussenzveig, D. R., Faria, A. M. C. & Fontoura, B. M. A., Dec 3 2015, In : Scientific Reports. 5, 17655.

Research output: Contribution to journalArticle

Immunologic Factors
Inflammation
COP-Coated Vesicles
T-Lymphocytes
Nuclear Pore
2009
19 Citations (Scopus)

Vesicular stomatitis virus inhibits mitotic progression and triggers cell death

Chakraborty, P., Seemann, J., Mishra, R. K., Wei, J. H., Weil, L., Nussenzveig, D. R., Heiber, J., Barber, G. N., Dasso, M. & Fontoura, B. M. A., 2009, In : EMBO Reports. 10, 10, p. 1154-1160 7 p.

Research output: Contribution to journalArticle

Vesicular Stomatitis
Cell death
Viruses
Cell Death
Ribonucleoproteins
2008
45 Citations (Scopus)

NFAR-1 and -2 modulate translation and are required for efficient host defense

Pfeifer, I., Elsby, R., Fernandez, M., Faria, P. A., Nussenzveig, D. R., Lossos, I. S., Fontoura, B. M. A., Martin, W. D. & Barber, G. N., Mar 18 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 11, p. 4173-4178 6 p.

Research output: Contribution to journalArticle

Messenger RNA
Vesicular Stomatitis
Ribonucleoproteins
Double-Stranded RNA
Virus Diseases

Plasmodium Circumsporozoite Protein Promotes the Development of the Liver Stages of the Parasite (DOI: 10.1016/j.cell.2007.09.013)

Singh, A. P., Buscaglia, C. A., Wang, Q., Levay, A., Nussenzweig, D. R., Walker, J. R., Winzeler, E. A., Fujii, H., Fontoura, B. M. A. & Nussenzweig, V., Apr 18 2008, In : Cell. 133, 2, p. 375 1 p.

Research output: Contribution to journalArticle

Liver
Protozoan circumsporozoite protein
Parasites
2007
185 Citations (Scopus)

Influenza virus targets the mRNA export machinery and the nuclear pore complex

Satterly, N., Tsai, P. L., Van Deursen, J., Nussenzveig, D. R., Wang, Y., Faria, P. A., Levay, A., Levy, D. E. & Fontoura, B. M. A., Feb 6 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 6, p. 1853-1858 6 p.

Research output: Contribution to journalArticle

Nuclear Pore
Orthomyxoviridae
Messenger RNA
Virus Replication
Human Influenza
140 Citations (Scopus)

Plasmodium Circumsporozoite Protein Promotes the Development of the Liver Stages of the Parasite

Singh, A. P., Buscaglia, C. A., Wang, Q., Levay, A., Nussenzweig, D. R., Walker, J. R., Winzeler, E. A., Fujii, H., Fontoura, B. M. A. & Nussenzweig, V., Nov 2 2007, In : Cell. 131, 3, p. 492-504 13 p.

Research output: Contribution to journalArticle

Liver
Parasites
Hepatocytes
Plasmodium
Malaria
2006
65 Citations (Scopus)

The nucleoporin Nup96 is required for proper expression of interferon-regulated proteins and functions

Faria, A. M. C., Levay, A., Wang, Y., Kamphorst, A. O., Rosa, M. L. P., Nussenzveig, D. R., Balkan, W., Chook, Y. M., Levy, D. E. & Fontoura, B. M. A., Mar 2006, In : Immunity. 24, 3, p. 295-304 10 p.

Research output: Contribution to journalArticle

Interferons
Proteins
nuclear pore complex protein 96
T-Lymphocytes
Cell Nucleus Active Transport
2005
38 Citations (Scopus)

Viral interactions with the nuclear transport machinery: Discovering and disrupting pathways

Fontoura, B. M. A., Faria, P. A. & Nussenzveig, D. R., Feb 2005, In : IUBMB Life. 57, 2, p. 65-72 8 p.

Research output: Contribution to journalArticle

Cell Nucleus Active Transport
Viruses
Machinery
Messenger RNA
Nuclear Proteins
1999
38 Citations (Scopus)

Glycosylation is important for binding to human calcitonin receptors

Ho, H. H., Gilbert, M. T., Nussenzveig, D. R. & Gershengorn, M. C., Feb 9 1999, In : Biochemistry. 38, 6, p. 1866-1872 7 p.

Research output: Contribution to journalArticle

Calcitonin Receptors
Glycosylation
salmon calcitonin
Substitution reactions
Calcitonin
1998
44 Citations (Scopus)

A hydrophobic cluster between transmembrane helices 5 and 6 constrains the thyrotropin-releasing hormone receptor in an inactive conformation

Colson, A. O., Perlman, J. H., Jinsi-Parimoo, A., Nussenzveig, D. R., Osman, R. & Gershengorn, M. C., 1998, In : Molecular Pharmacology. 54, 6, p. 968-978 11 p.

Research output: Contribution to journalArticle

Thyrotropin Releasing Hormone Receptors
Thyrotropin-Releasing Hormone
Alanine
Phenylalanine
Midazolam
5 Citations (Scopus)
Calcitonin Receptors
Madin Darby Canine Kidney Cells
salmon calcitonin
Confocal microscopy
Biotinylation
1997
25 Citations (Scopus)

Human calcitonin receptors exhibit agonist-independent (constitutive) signaling activity

Cohen, D. P., Thaw, C. N., Varma, A., Gershengorn, M. C. & Nussenzveig, D. R., 1997, In : Endocrinology. 138, 4, p. 1400-1405 6 p.

Research output: Contribution to journalArticle

Calcitonin Receptors
G-Protein-Coupled Receptors
Protein Isoforms
Parathyroid Hormone Receptor Type 1
Parathyroid Hormone-Related Protein
1996
6 Citations (Scopus)

Intracellular retention and rapid degradation of human calcitonin receptors overexpressed in COS cells

Dermer, S. J., Cohen, D. P., Thaw, C. N., Nussenzveig, D. R. & Gershengorn, M. C., 1996, In : Endocrinology. 137, 12, p. 5502-5508 7 p.

Research output: Contribution to journalArticle

Calcitonin Receptors
COS Cells
Epitopes
salmon calcitonin
Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase
6 Citations (Scopus)

Iodocalcitonin binds to human calcitonin receptors with higher affinity than calcitonin

Cohen, D. P., Nussenzveig, D. R. & Gershengorn, M. C., 1996, In : Endocrinology. 137, 10, p. 4507-4510 4 p.

Research output: Contribution to journalArticle

salmon calcitonin
Calcitonin Receptors
Calcitonin
Madin Darby Canine Kidney Cells
1995
32 Citations (Scopus)

A constitutively active mutant thyrotropin-releasing hormone receptor is chronically down-regulated in pituitary cells: Evidence using chlordiazepoxide as a negative antagonist

Heinflink, M., Nussenzveig, D. R., Grimberg, H., Lupu-Meiri, M., Oron, Y. & Gershengorn, M. C., Nov 1995, In : Molecular Endocrinology. 9, 11, p. 1455-1460 6 p.

Research output: Contribution to journalArticle

Thyrotropin Releasing Hormone Receptors
Chlordiazepoxide
Bombesin
Inositol Phosphates
Guanine Nucleotides
63 Citations (Scopus)

A disulfide bond between conserved extracellular cysteines in the thyrotropin-releasing hormone receptor is critical for binding

Perlman, J. H., Wang, W., Nussenzveig, D. R. & Gershengorn, M. C., 1995, In : Journal of Biological Chemistry. 270, 42, p. 24682-24685 4 p.

Research output: Contribution to journalArticle

Thyrotropin Releasing Hormone Receptors
Thyrotropin-Releasing Hormone
Disulfides
Cysteine
Dithiothreitol
38 Citations (Scopus)

Alternative splicing of a 48-nucleotide exon generates two isoforms of the human calcitonin receptor

Nussenzveig, D. R., Mathew, S. & Gershengorn, M. C., 1995, In : Endocrinology. 136, 5, p. 2047-2051 5 p.

Research output: Contribution to journalArticle

Calcitonin Receptors
Alternative Splicing
Exons
Protein Isoforms
Nucleotides
11 Citations (Scopus)
Thyrotropin-Releasing Hormone
Xenopus
Protein Kinase C
Oocytes
Calcium
38 Citations (Scopus)
Thyrotropin Releasing Hormone Receptors
Thyrotropin-Releasing Hormone
Xenopus
Oocytes
Tail
1994
37 Citations (Scopus)

Expression of thyrotropin-releasing hormone receptors by adenovirus-mediated gene transfer reveals that thyrotropin-releasing hormone desensitization is cell specific

Falck-Pedersen, E., Heinflink, M., Alvira, M., Nussenzveig, D. R. & Gershengorn, M. C., Apr 1994, In : Molecular Pharmacology. 45, 4, p. 684-689 6 p.

Research output: Contribution to journalArticle

Thyrotropin Releasing Hormone Receptors
Thyrotropin-Releasing Hormone
Adenoviridae
Genes
Gene Transfer Techniques
78 Citations (Scopus)
Calcitonin Receptors
Artificial Receptors
Synthetic Genes
Inositol Phosphates
Second Messenger Systems
5 Citations (Scopus)

The hemispheric functional expression of the thyrotropin-releasing-hormone receptor is not determined by the receptors' physical distribution

Matus-Leibovitch, N., Nussenzveig, D. R., Gershengorn, M. C. & Oron, Y., 1994, In : Biochemical Journal. 303, 1, p. 129-134 6 p.

Research output: Contribution to journalArticle

Thyrotropin Releasing Hormone Receptors
Animals
Signal transduction
Antisense Oligonucleotides
Inositol
21 Citations (Scopus)
Thyrotropin Releasing Hormone Receptors
Gene transfer
Thyrotropin-Releasing Hormone
Phosphatidylinositols
Adenoviridae
11 Citations (Scopus)
Thyrotropin Releasing Hormone Receptors
Cyclic AMP
Chemical activation
Cells
Inositol Phosphates
1993
109 Citations (Scopus)

Agonist-stimulated internalization of the thyrotropin-releasing hormone receptor is dependent on two domains in the receptor carboxyl terminus

Nussenzveig, D. R., Heinflink, M. & Gershengorn, M. C., Feb 5 1993, In : Journal of Biological Chemistry. 268, 4, p. 2389-2392 4 p.

Research output: Contribution to journalArticle

Thyrotropin Releasing Hormone Receptors
Codon
Acids
Inositol Phosphates
Thyrotropin-Releasing Hormone
30 Citations (Scopus)
Thyrotropin Releasing Hormone Receptors
Guanine Nucleotides
Type C Phospholipases
Protein C
Carrier Proteins
1992
55 Citations (Scopus)

Dynamics of atrial natriuretic factor-guanylate cyclase receptors and receptor-ligand complexes in cultured glomerular mesangial and renomedullary interstitial cells

Koh, G. Y., Nussenzveig, D. R., Okolicany, J., Price, D. A. & Maack, T., Jun 15 1992, In : Journal of Biological Chemistry. 267, 17, p. 11987-11994 8 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor Receptors
Guanylate Cyclase
Atrial Natriuretic Factor
Ligands
Hydrolysis
39 Citations (Scopus)
Thyrotropin-Releasing Hormone
G-Protein-Coupled Receptors
Thyrotropin Releasing Hormone Receptors
Ligands
Peptides
1991
24 Citations (Scopus)
Losartan
Angiotensin Receptor Antagonists
Cultured Cells
Kidney
Angiotensin II
1990
42 Citations (Scopus)
Atrial Natriuretic Factor Receptors
Atrial Natriuretic Factor
Kidney
Guanylate Cyclase
Cyclic GMP
129 Citations (Scopus)

Cellular mechanisms of the clearance function of type C receptors of atrial natriuretic factor

Nussenzveig, D. R., Lewicki, J. A. & Maack, T., Dec 5 1990, In : Journal of Biological Chemistry. 265, 34, p. 20952-20958 7 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Ligands
Monoiodotyrosine
atrial natriuretic factor receptor C
Transition Temperature
1988
2 Citations (Scopus)

Clearance receptors of atrial natriuretic factor.

Maack, T., Almeida, F. A., Suzuki, M. & Nussenzveig, D. R., 1988, In : Contributions to Nephrology. 68, p. 58-65 8 p.

Research output: Contribution to journalArticle

Kidney Glomerulus
Atrial Natriuretic Factor Receptors
Cell Surface Receptors
Atrial Natriuretic Factor
Hydrolysis
1987
16 Citations (Scopus)

Binding and functional effects of atrial natriuretic factor in isolated rat kidney

Suzuki, M., Almeida, F. A., Nussenzveig, D. R., Sawyer, D. & Maack, T., 1987, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 253, 5

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Kidney
Binding Sites
Electrolytes
Hemodynamics
810 Citations (Scopus)

Physiological role of silent receptors of atrial natriuretic factor

Maack, T., Suzuki, M., Almeida, F. A., Nussenzveig, D., Scarborough, R. M., Mcenroe, G. A. & Lewicki, J. A., 1987, In : Science. 238, 4827, p. 675-678 4 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor Receptors
Atrial Natriuretic Factor
Kidney
Buffers
Hemodynamics