• 3747 Citations
  • 36 h-Index
1974 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

49th Forum in Immunology: Discussion

Labrecque, N., Thibodeau, J., Sekaly, R. P., Karp, D. R., Gascoigne, N. R. J., Fraser, J. D., Hudson, K. R., Simpson, E., Acha-Orbea, H., Woodland, D. L., Blackman, M. A., Huber, B. T. & Lafon, M., Jan 1 1993, In : Research in Immunology. 144, 3, p. 214-222 9 p.

Research output: Contribution to journalArticle

Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations

Kim-Howard, X., Sun, C., Molineros, J. E., Maiti, A. K., Chandru, H., Adler, A., Wiley, G. B., Kaufman, K. M., Kottyan, L., Guthridge, J. M., Rasmussen, A., Kelly, J., Sánchez, E., Raj, P., Li, Q. Z., Bang, S. Y., Lee, H. S., Kim, T. H., Kang, Y. M., Suh, C. H. & 35 others, Chung, W. T., Park, Y. B., Choe, J. Y., Shim, S. C., Lee Shin-Seok, S. S., Han, B. G., Olsen, N. J., Karp, D. R., Moser, K., Pons-Estel, B. A., Wakeland, E. K., James, J. A., Harley, J. B., Bae, S. C., Gaffney, P. M., Alarcón-Riquelme, M., Acevedo, E., La Torre, I. G. D., Maradiaga-Ceceña, M. A., Cardiel, M. H., Esquivel-Valerio, J. A., Rodriguez-Amado, J., Moctezuma, J. F., Miranda, P., Perandones, C., Castel, C., Laborde, H. A., Alba, P., Musuruana, J., Goecke, A., Foster, C., Orozco, L., Baca, V., Looger, L. L. & Nath, S. K., Mar 2014, In : Human molecular genetics. 23, 6, p. 1656-1668 13 p., ddt532.

Research output: Contribution to journalArticle

31 Scopus citations

Amino acid sequence homologies and glycosylation differences between the fourth component of murine complement and sex-limited protein

Karp, D. R., Parker, K. L., Shreffler, D. C., Slaughter, C. & Capra, J. D., 1982, In : Proceedings of the National Academy of Sciences of the United States of America. 79, 20 I, p. 6347-6349 3 p.

Research output: Contribution to journalArticle

17 Scopus citations

Analyses of the staphylococcal toxin binding sites on MHC class II molecules

Karp, D. R., 1993, In : Research in Immunology. 144, 3, p. 181-184 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

A new type of metal recognition by human T cells: Contact residues for peptide-independent bridging of T cell receptor and major histocompatibility complex by nickel

Gamerdinger, K., Moulon, C., Karp, D. R., Van Bergen, J., Koning, F., Wild, D., Pflugfelder, U. & Weltzien, H. U., May 19 2003, In : Journal of Experimental Medicine. 197, 10, p. 1345-1353 9 p.

Research output: Contribution to journalArticle

109 Scopus citations

Antinuclear Antibodies Are Associated With All-Cause Mortality and Cardiovascular Outcomes in the General Population

Solow, E. B., Vongpatanasin, W., Skaug, B., Karp, D. R., Ayers, C. & de Lemos, J. A., Jun 23 2015, In : Journal of the American College of Cardiology. 65, 24, p. 2669-2670 2 p., 21269.

Research output: Contribution to journalArticle

11 Scopus citations
4 Scopus citations

A search for blood biomarkers for autism: Peptoids

Zaman, S., Yazdani, U., Deng, Y., Li, W., Gadad, B. S., Hynan, L., Karp, D., Roatch, N., Schutte, C., Nathan Marti, C., Hewitson, L. & German, D. C., Jan 14 2016, In : Scientific Reports. 6, 19164.

Research output: Contribution to journalArticle

14 Scopus citations

Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals

Jog, N. R., Young, K. A., Munroe, M. E., Harmon, M. T., Guthridge, J. M., Kelly, J. A., Kamen, D. L., Gilkeson, G. S., Weisman, M. H., Karp, D. R., Gaffney, P. M., Harley, J. B., Wallace, D. J., Norris, J. M. & James, J. A., Jan 1 2019, In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

4 Scopus citations

A subset of CD163+ macrophages displays mixed polarizations in discoid lupus skin

Chong, B. F., Tseng, L. C., Hosler, G. A., Teske, N. M., Zhang, S., Karp, D. R., Olsen, N. J. & Mohan, C., Nov 13 2015, In : Arthritis Research and Therapy. 17, 1, 324.

Research output: Contribution to journalArticle

13 Scopus citations

Autoantibodies and SLE - The threshold for disease

Olsen, N. J. & Karp, D. R., Mar 1 2014, In : Nature Reviews Rheumatology. 10, 3, p. 181-186 6 p.

Research output: Contribution to journalReview article

57 Scopus citations

Autoantibody profiling to follow evolution of lupus syndromes

Olsen, N. J., Li, Q. Z., Quan, J., Wang, L., Mutwally, A. & Karp, D. R., Jul 27 2012, In : Arthritis Research and Therapy. 14, 4, R174.

Research output: Contribution to journalArticle

46 Scopus citations

Autoantibody profiling to identify individuals at risk for systemic lupus erythematosus

Wandstrat, A. E., Carr-Johnson, F., Branch, V., Gray, H., Fairhurst, A. M., Reimold, A., Karp, D., Wakeland, E. K. & Olsen, N. J., Nov 1 2006, In : Journal of Autoimmunity. 27, 3, p. 153-160 8 p.

Research output: Contribution to journalArticle

113 Scopus citations

Blood biomarker for Parkinson disease: peptoids

Yazdani, U., Zaman, S., Hynan, L. S., Brown, L. S., Dewey, R. B., Karp, D. & German, D. C., Dec 1 2016, In : npj Parkinson's Disease. 2, 1, 16012.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

CD21 augments antigen presentation in immune individuals

Boadde, S. A., Michael Holers, V. & Karp, D. R., Dec 1 1996, In : FASEB Journal. 10, 6, p. A1212

Research output: Contribution to journalArticle

CD21 augments antigen presentation in immune individuals

Boackle, S. A., Holers, V. M. & Karp, D. R., Jan 1 1997, In : European Journal of Immunology. 27, 1, p. 122-129 8 p.

Research output: Contribution to journalArticle

48 Scopus citations
Open Access
9 Scopus citations

Characterization of the murine C4 precursor (Pro-C4): Evidence that the carboxy-terminal subunit is the C4 γ-chain

Karp, D. R., Parker, K. L., Shreffler, D. C. & Capra, J. D., Jan 1 1981, In : Journal of Immunology. 126, 5, p. 2060-2061 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Class II MHC molecules and the HIV gp120 envelope protein interact with functionally distinct regions of the CD4 molecule

Lamarre, D., Capon, D. J., Karp, D. R., Gregory, T., Long, E. O. & Sekaly, R. P., Jan 1 1989, In : EMBO Journal. 8, 11, p. 3271-3277 7 p.

Research output: Contribution to journalArticle

62 Scopus citations

Clinical and Serologic Features in Patients With Incomplete Lupus Classification Versus Systemic Lupus Erythematosus Patients and Controls

Aberle, T., Bourn, R. L., Munroe, M. E., Chen, H., Roberts, V. C., Guthridge, J. M., Bean, K., Robertson, J. M., Sivils, K. L., Rasmussen, A., Liles, M., Merrill, J. T., Harley, J. B., Olsen, N. J., Karp, D. R. & James, J. A., Dec 2017, In : Arthritis Care and Research. 69, 12, p. 1780-1788 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus

Young, K. A., Munroe, M. E., Guthridge, J. M., Kamen, D. L., Niewold, T. B., Gilkeson, G. S., Weisman, M. H., Ishimori, M. L., Kelly, J., Gaffney, P. M., Sivils, K. H., Lu, R., Wallace, D. J., Karp, D. R., Harley, J. B., James, J. A. & Norris, J. M., Jun 9 2016, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

20 Scopus citations

Complement and systemic lupus erythematosus

Karp, D. R., Sep 1 2005, In : Current Opinion in Rheumatology. 17, 5, p. 538-542 5 p.

Research output: Contribution to journalReview article

25 Scopus citations

Complement component C3d-antigen complexes can either augment or inhibit B lymphocyte activation and humoral immunity in mice depending on the degree of CD21/CD19 complex engagement

Lee, Y., Haas, K. M., Gor, D. O., Ding, X., Karp, D. R., Greenspan, N. S., Poe, J. C. & Tedder, T. F., Dec 15 2005, In : Journal of Immunology. 175, 12, p. 8011-8023 13 p.

Research output: Contribution to journalArticle

Open Access
44 Scopus citations

Complement in Health and Disease

Karp, D. R. & Holers, V. M., Jul 2011, Goldman's Cecil Medicine: Twenty Fourth Edition. Elsevier Inc., Vol. 1. p. 239-244 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Complement opsonization is required for presentation of immune complexes by resting peripheral blood B cells

Boackle, S. A., Morris, M. A., Holers, V. M. & Karp, D. R., Dec 15 1998, In : Journal of Immunology. 161, 12, p. 6537-6543 7 p.

Research output: Contribution to journalArticle

62 Scopus citations

Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses

Haas, K. M., Hasegawa, M., Steeber, D. A., Poe, J. C., Zabel, M. D., Bock, C. B., Karp, D. R., Briles, D. E., Weis, J. H. & Tedder, T. F., Dec 1 2002, In : Immunity. 17, 6, p. 713-723 11 p.

Research output: Contribution to journalArticle

118 Scopus citations

Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein

Boackle, S. A., Holers, V. M., Chen, X., Szakonyi, G., Karp, D. R., Wakeland, E. K. & Morel, L., Jan 1 2001, In : Immunity. 15, 5, p. 775-785 11 p.

Research output: Contribution to journalArticle

175 Scopus citations

Cross-sectional imaging of adult crystal and inflammatory arthropathies

Soldatos, T., Pezeshk, P., Ezzati, F., Karp, D. R., Taurog, J. D. & Chhabra, A., May 21 2016, (Accepted/In press) In : Skeletal Radiology. p. 1-19 19 p.

Research output: Contribution to journalArticle

3 Scopus citations

Cutting Edge: C3d Functions as a Molecular Adjuvant in the Absence of CD21/35 Expression

Haas, K. M., Toapanta, F. R., Oliver, J. A., Poe, J. C., Weis, J. H., Karp, D. R., Bower, J. F., Ross, T. M. & Tedder, T. F., May 15 2004, In : Journal of Immunology. 172, 10, p. 5833-5837 5 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations

Development of risk profiles for systemic lupus erythematosus

Olsen, N. J., Wandstrat, A. E. & Karp, D. R., Oct 1 2007, In : Future Rheumatology. 2, 5, p. 507-514 8 p.

Research output: Contribution to journalReview article

Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features

Munroe, M. E., Young, K. A., Kamen, D. L., Guthridge, J. M., Niewold, T. B., Costenbader, K. H., Weisman, M. H., Ishimori, M. L., Wallace, D. J., Gilkeson, G. S., Karp, D. R., Harley, J. B., Norris, J. M. & James, J. A., Mar 1 2017, In : Arthritis and Rheumatology. 69, 3, p. 630-642 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Discovery of biomarkers for systemic lupus erythematosus using a library of synthetic autoantigen surrogates

Quan, J., Lakhanpal, A., Reddy, M. M., Zaman, S., Li, Q. Z., German, D. C., Olsen, N. J., Kodadek, T. & Karp, D. R., 2014, In : Journal of Immunological Methods. 402, 1-2, p. 23-34 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Discovery of biomarkers for systemic lupus erythematosus using a library of synthetic autoantigen surrogates.

Quan, J., Lakhanpal, A., Reddy, M. M., Zaman, S., Li, Q. Z., German, D. C., Olsen, N. J., Kodadek, T. & Karp, D. R., 2014, Journal of immunological methods. 1-2 ed. Vol. 402. p. 23-34 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Distinct binding sites on HLA-DR for invariant chain and staphylococcal enterotoxins

Karp, D. R., Jenkins, R. N. & Long, E. O., Oct 15 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 20, p. 9657-9661 5 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Efficient cDNA expression vectors for stable and transient expression of HLA-DR in transfected fibroblast and lymphoid cells

Long, E. O., Rosen-Bronson, S., Karp, D. R., Malnati, M., Sekaly, R. P. & Jaraquemada, D., Aug 1991, In : Human Immunology. 31, 4, p. 229-235 7 p.

Research output: Contribution to journalArticle

122 Scopus citations

Ethical and practical issues associated with aggregating databases

Karp, D. R., Carlin, S., Cook-Deegan, R., Ford, D. E., Geller, G., Glass, D. N., Greely, H., Guthridge, J., Kahn, J., Kaslow, R., Kraft, C., MacQueen, K., Malin, B., Scheuerman, R. H. & Sugarman, J., Sep 2008, In : PLoS Medicine. 5, 9, p. 1333-1337 5 p., e190.

Research output: Contribution to journalReview article

29 Scopus citations

Ethics of data sharing and handling of genetic information

Malin, B. A., Karp, D. & Scheuermann, R. H., Jan 1 2012, Clinical Research: From Proposal to Implementation. Wolters Kluwer Health Adis (ESP), p. 41-56 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Expression of γ-Glutamyl Transpeptidase Protects Ramos B Cells from Oxidation-induced Cell Death

Karp, D. R., Shimooku, K. & Lipsky, P. E., Feb 9 2001, In : Journal of Biological Chemistry. 276, 6, p. 3798-3804 7 p.

Research output: Contribution to journalArticle

146 Scopus citations

FcγRIIB mediates C-reactive protein inhibition of endothelial NO synthase

Mineo, C., Gormley, A. K., Yuhanna, I. S., Osborne-Lawrence, S., Gibson, L. L., Hahner, L., Shohet, R. V., Black, S., Salmon, J. E., Samols, D., Karp, D. R., Thomas, G. D. & Shaul, P. W., Nov 1 2005, In : Circulation research. 97, 11, p. 1124-1131 8 p.

Research output: Contribution to journalArticle

91 Scopus citations

Finding lupus in the ANA haystack

Olsen, N. J. & Karp, D. R., Feb 2 2020, In : Lupus Science and Medicine. 7, 1, e000384.

Research output: Contribution to journalReview article

Open Access

Functional activity of staphylococcal enterotoxin A requires interactions with both the alpha and beta chains of HLA-DR

Dowd, J. E., Karr, R. W. & Karp, D. R., Nov 1 1996, In : Molecular Immunology. 33, 16, p. 1267-1274 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Generation of recombinant human C3dg tetramers for the analysis of CD21 binding and function

Henson, S. E., Smith, D., Boackle, S. A., Holers, V. M. & Karp, D. R., Dec 1 2001, In : Journal of Immunological Methods. 258, 1-2, p. 97-109 13 p.

Research output: Contribution to journalArticle

37 Scopus citations

Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus

Sawalha, A. H., Kaufman, K. M., Kelly, J. A., Adler, A. J., Aberle, T., Kilpatrick, J., Wakeland, E. K., Li, Q. Z., Wandstrat, A. E., Karp, D. R., James, J. A., Merrill, J. T., Lipsky, P. & Harley, J. B., Apr 2008, In : Annals of the Rheumatic Diseases. 67, 4, p. 458-461 4 p.

Research output: Contribution to journalArticle

138 Scopus citations

Genetic variation in glycosylation of the fourth component of murine complement. Association with hemolytic activity

Karp, D. R., Atkinson, J. P. & Shreffler, D. C., Dec 1 1982, In : Journal of Biological Chemistry. 257, 13, p. 7330-7335 6 p.

Research output: Contribution to journalArticle

73 Scopus citations

H-2 S region determined polymorphic variants of the C4, Slp, C2, and B complement proteins: A compilation

Atkinson, J. P., Karp, D. R., Seeskin, E. P., Killion, C. C., Rosa, P. A., Newell, S. L. & Shreffler, D. C., Dec 1982, In : Immunogenetics. 16, 6, p. 617-623 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
Open Access
22 Scopus citations

Identification of HLA-DR1 β chain residues critical for binding staphylococcal enterotoxins A and E

Karp, D. R. & Long, E. O., Feb 1 1992, In : Journal of Experimental Medicine. 175, 2, p. 415-424 10 p.

Research output: Contribution to journalArticle

Open Access
106 Scopus citations
3 Scopus citations

IgG and IgM autoantibody differences in discoid and systemic lupus patients

Chong, B. F., Tseng, L. C., Lee, T., Vasquez, R., Li, Q. Z., Zhang, S., Karp, D. R., Olsen, N. J. & Mohan, C., Dec 2012, In : Journal of Investigative Dermatology. 132, 12, p. 2770-2779 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Increased prevalence of activated CD70+CD4+ T cells in the periphery of patients with systemic lupus erythematosus

Han, B. K., White, A. M., Dao, K. H., Karp, D. R., Wakeland, E. K. & Davis, L. S., Sep 22 2005, In : Lupus. 14, 8, p. 598-606 9 p.

Research output: Contribution to journalArticle

37 Scopus citations