• 11461 Citations
  • 49 h-Index
1989 …2018

Research output per year

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Research Output

Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration

Edwards, S., Whisler, K. N., Fuller, D. C., Orsulak, P. J. & Self, D. W., Feb 1 2007, In : Neuropsychopharmacology. 32, 2, p. 354-366 13 p.

Research output: Contribution to journalArticle

65 Scopus citations

Adenosine A 1 and dopamine D 1 receptor regulation of AMPA receptor phosphorylation and cocaine-seeking behavior

Hobson, B. D., O'Neill, C. E., Levis, S. C., Monteggia, L. M., Neve, R. L., Self, D. W. & Bachtell, R. K., Sep 1 2013, In : Neuropsychopharmacology. 38, 10, p. 1974-1983 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Anandamide: A candidate neurotransmitter heads for the big leagues

Self, D. W., Apr 1 1999, In : Nature neuroscience. 2, 4, p. 303-304 2 p.

Research output: Contribution to journalShort survey

20 Scopus citations

A neurobiological basis for substance abuse comorbidity in schizophrenia

Chambers, R. A., Krystal, J. H. & Self, D. W., Jul 15 2001, In : Biological Psychiatry. 50, 2, p. 71-83 13 p.

Research output: Contribution to journalReview article

395 Scopus citations

Antisense-induced reduction in nucleus accumbens cyclic AMP response element binding protein attenuates cocaine reinforcement

Choi, K. H., Whisler, K., Graham, D. L. & Self, D. W., Jan 9 2006, In : Neuroscience. 137, 2, p. 373-383 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

A paradigm to investigate the self-regulation of cocaine administration in humans

Sughondhabirom, A., Jain, D., Gueorguieva, R., Coric, V., Berman, R., Lynch, W. J., Self, D., Jatlow, P. & Malison, R. T., Jul 1 2005, In : Psychopharmacology. 180, 3, p. 436-446 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Applications of a rat multiple tissue gene expression data set

Walker, J. R., Su, A. I., Self, D. W., Hogenesch, J. B., Lapp, H., Maier, R., Hoyer, D. & Bilbe, G., Apr 1 2004, In : Genome Research. 14, 4, p. 742-749 8 p.

Research output: Contribution to journalArticle

73 Scopus citations

BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors

Anderson, E. M., Wissman, A. M., Chemplanikal, J., Buzin, N., Guzman, D., Larson, E. B., Neve, R. L., Nestler, E. J., Cowan, C. W. & Self, D. W., Aug 29 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 35, p. 9469-9474 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Biochemical adaptations in the mesolimbic dopamine system in response to heroin self‐administration

Self, D. W., McClenahan, A. W., Beitner-Johnson, D., Terwilliger, R. Z. & Nestler, E. J., Dec 1995, In : Synapse. 21, 4, p. 312-318 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum

Kumar, A., Choi, K. H., Renthal, W., Tsankova, N. M., Theobald, D. E. H., Truong, H. T., Russo, S. J., LaPlant, Q., Sasaki, T. S., Whistler, K. N., Neve, R. L., Self, D. W. & Nestler, E. J., Oct 20 2005, In : Neuron. 48, 2, p. 303-314 12 p.

Research output: Contribution to journalArticle

570 Scopus citations

Cocaine abuse takes a shot

Self, D. W., Dec 14 1995, In : Nature. 378, 6558, p. 666-667 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

Cocaine self-administration behaviors in ClockΔ19 mice

Ozburn, A. R., Larson, E. B., Self, D. W. & McClung, C. A., Sep 1 2012, In : Psychopharmacology. 223, 2, p. 169-177 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Comparison of transgenic strategies for behavioral neuroscience studies in rodents

Self, D. W., Dec 1 1999, In : Psychopharmacology. 147, 1, p. 35-37 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Coupling of subtypes of the muscarinic receptor to adenylate cyclase in the corpus striatum and heart

Ehlert, F. J., Delen, F. M., Yun, S. H., Friedman, D. J. & Self, D. W., Jan 1 1989, In : Journal of Pharmacology and Experimental Therapeutics. 251, 2, p. 660-671 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Differential ability of D1 and D2 dopamine receptor agonists to induce and modulate expression and reinstatement of cocaine place preference in rats

Graham, D. L., Hoppenot, R., Hendryx, A. & Self, D. W., Apr 1 2007, In : Psychopharmacology. 191, 3, p. 719-730 12 p.

Research output: Contribution to journalArticle

49 Scopus citations

Diminished role for dopamine D1 receptors in cocaine addiction?

Self, D. W., Jul 1 2014, In : Biological Psychiatry. 76, 1, p. 2-3 2 p.

Research output: Contribution to journalComment/debate

5 Scopus citations

Direct regulation of diurnal drd3 expression and cocaine reward by npas2

Ozburn, A. R., Falcon, E., Twaddle, A., Nugent, A. L., Gillman, A. G., Spencer, S. M., Arey, R. N., Mukherjee, S., Lyons-Weiler, J., Self, D. W. & McClung, C. A., Mar 1 2015, In : Biological Psychiatry. 77, 5, p. 425-433 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Distinct patterns of ΔFosB induction in brain by drugs of abuse

Perrotti, L. I., Weaver, R. R., Robison, B., Renthal, W., Maze, I., Yazdani, S., Elmore, R. G., Knapp, D. J., Selley, D. E., Martin, B. R., Sim-Selley, L., Bachtell, R. K., Self, D. W. & Nestler, E. J., May 1 2008, In : Synapse. 62, 5, p. 358-369 12 p.

Research output: Contribution to journalArticle

132 Scopus citations

Drug Dependence and Addiction: Neural Substrates

Self, D. & Tamminga, C. A., Feb 1 2004, In : American Journal of Psychiatry. 161, 2, 1 p.

Research output: Contribution to journalArticle

11 Scopus citations

Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse

Graham, D. L., Edwards, S., Bachtell, R. K., DiLeone, R. J., Rios, M. & Self, D. W., Aug 1 2007, In : Nature neuroscience. 10, 8, p. 1029-1037 9 p.

Research output: Contribution to journalArticle

289 Scopus citations

Effects of adenosine A2A receptor stimulation on cocaine-seeking behavior in rats

Bachtell, R. K. & Self, D. W., Jul 30 2009, In : Psychopharmacology. 206, 3, p. 469-478 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Effects of D1 and D2-selective antagonists on self-administration of the D1 agonist SKF 82958

Self, D. W., Lam, D. M., Kossuth, S. R. & Stein, L., Jan 1 1993, In : NIDA Research Monograph Series. 132, 1 p.

Research output: Contribution to journalArticle

4 Scopus citations

Effects of dopamine D2 receptor (DRD2) and transporter (SLC6A3) polymorphisms on smoking cue-induced cigarette craving among African-American smokers

Erblich, J., Lerman, C., Self, D. W., Diaz, G. A. & Bovbjerg, D. H., Apr 1 2005, In : Molecular psychiatry. 10, 4, p. 407-414 8 p.

Research output: Contribution to journalArticle

65 Scopus citations

Effects of intranucleus accumbens shell administration of dopamine agonists and antagonists on cocaine-taking and cocaine-seeking behaviors in the rat

Bachtell, R. K., Whisler, K., Karanian, D. & Self, D. W., Nov 1 2005, In : Psychopharmacology. 183, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

123 Scopus citations

Effects of the novel D1 dopamine receptor agonist ABT-431 on cocaine self-administration and reinstatement

Self, D. W., Karanian, D. A. & Spencer, J. J., Jan 1 2000, In : Annals of the New York Academy of Sciences. 909, p. 133-144 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

Emergence of context-associated GluR 1 and ERK phosphorylation in the nucleus accumbens core during withdrawal from cocaine self-administration

Edwards, S., Bachtell, R. K., Guzman, D., Whisler, K. N. & Self, D. W., Jul 1 2011, In : Addiction Biology. 16, 3, p. 450-457 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Enhanced acquisition of cocaine self-administration by increasing percentages of C57BL/6J genes in mice with a nonpreferring outbred background

Ruiz-Durántez, E., Hall, S. K., Steffen, C. & Self, D. W., Jul 1 2006, In : Psychopharmacology. 186, 4, p. 553-560 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Erratum: Applications of a rat multiple tissue gene expression data set (Genome Research (2004) vol. 14 (742-749))

Walker, J. R., Su, A. I., Self, D. W., Hogenesch, J. B., Lapp, H., Sturchler, C., Kinnunen, A., Maier, R., Hoyer, D. & Bilbe, G., Jul 1 2004, In : Genome Research. 14, 7, 1 p.

Research output: Contribution to journalComment/debate

Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress

Berton, O., McClung, C. A., DiLeone, R. J., Krishnan, V., Renthal, W., Russo, S. J., Graham, D., Tsankova, N. M., Bolanos, C. A., Rios, M., Monteggia, L. M., Self, D. W. & Nestler, E. J., Feb 10 2006, In : Science. 311, 5762, p. 864-868 5 p.

Research output: Contribution to journalArticle

1323 Scopus citations

Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine

Kelz, M. B., Chen, J., Carlezon, W. A., Whisler, K., Gilden, L., Beckmann, A. M., Steffen, C., Zhang, Y. J., Marotti, L., Self, D. W., Tkatch, T., Baranauskas, G., Surmeler, D. J., Neve, R. L., Duman, R. S., Picciotto, M. R. & Nestler, E. J., Sep 16 1999, In : Nature. 401, 6750, p. 272-276 5 p.

Research output: Contribution to journalArticle

491 Scopus citations

Extinction-induced neuroplasticity attenuates stress-induced cocaine seeking: A state-dependent learning hypothesis

Self, D. W. & Choi, K. H., Sep 1 2004, In : Stress. 7, 3, p. 145-155 11 p.

Research output: Contribution to journalReview article

27 Scopus citations

Extinction-induced upregulation in AMPA receptors reduces cocaine-seeking behaviour

Sutton, M. A., Schmidt, E. F., Choi, K. H., Schad, C. A., Whisler, K., Simmons, D., Karanian, D. A., Monteggia, L. M., Neve, R. L. & Self, D. W., Jan 2 2003, In : Nature. 421, 6918, p. 70-75 6 p.

Research output: Contribution to journalArticle

264 Scopus citations

Extinction training regulates neuroadaptive responses to withdrawal from chronic cocaine self-administration

Self, D. W., Choi, K. H., Simmons, D., Walker, J. R. & Smagula, C. S., Sep 1 2004, In : Learning and Memory. 11, 5, p. 648-657 10 p.

Research output: Contribution to journalReview article

95 Scopus citations

Extinction training regulates tyrosine hydroxylase during withdrawal from cocaine self-administration.

Schmidt, E. F., Sutton, M. A., Schad, C. A., Karanian, D. A., Brodkin, E. S. & Self, D. W., Apr 1 2001, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 21, 7, p. RC137

Research output: Contribution to journalArticle

47 Scopus citations

Factors that determine a propensity for cocaine-seeking behavior during abstinence in rats

Sutton, M. A., Kamnian, D. A. & Self, D. W., Jun 1 2000, In : Neuropsychopharmacology. 22, 6, p. 626-641 16 p.

Research output: Contribution to journalArticle

75 Scopus citations

HDAC5 and Its Target Gene, Npas4, Function in the Nucleus Accumbens to Regulate Cocaine-Conditioned Behaviors

Taniguchi, M., Carreira, M. B., Cooper, Y. A., Bobadilla, A. C., Heinsbroek, J. A., Koike, N., Larson, E. B., Balmuth, E. A., Hughes, B. W., Penrod, R. D., Kumar, J., Smith, L. N., Guzman, D., Takahashi, J. S., Kim, T. K., Kalivas, P. W., Self, D. W., Lin, Y. & Cowan, C. W., Sep 27 2017, In : Neuron. 96, 1, p. 130-144 15 p.

Research output: Contribution to journalArticle

29 Scopus citations

Inactivation of G(i) and G(o) proteins in nucleus accumbens reduces both cocaine and heroin reinforcement

Self, D. W., Terwilliger, R. Z., Nestler, E. J. & Stein, L., Jan 1 1994, In : Journal of Neuroscience. 14, 10, p. 6239-6247 9 p.

Research output: Contribution to journalArticle

90 Scopus citations

Inactivation of NMDA receptors in the ventral tegmental area during cocaine self-administration prevents GluA1 upregulation but with paradoxical increases in cocaine-seeking behavior

Guzman, D., Carreira, M. B., Friedman, A. K., Adachi, M., Neve, R. L., Monteggia, L. M., Han, M. H., Cowan, C. W. & Self, D. W., Jan 17 2018, In : Journal of Neuroscience. 38, 3, p. 575-585 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Increased impulsivity during withdrawal from cocaine self-administration: Role for ΔFosB in the orbitofrontal cortex

Winstanley, C. A., Bachtell, R. K., Theobald, D. E. H., Laali, S., Green, T. A., Kumar, A., Chakravarty, S., Self, D. W. & Nestler, E. J., Feb 1 2009, In : Cerebral Cortex. 19, 2, p. 435-444 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Incubation of cue-induced reinstatement of cocaine, but not sucrose, seeking in C57BL/6J mice

Nugent, A. L., Anderson, E. M., Larson, E. B. & Self, D. W., Aug 1 2017, In : Pharmacology Biochemistry and Behavior. 159, p. 12-17 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine

Peakman, M. C., Colby, C., Perrotti, L. I., Tekumalla, P., Carle, T., Ulery, P., Chao, J., Duman, C., Steffen, C., Monteggia, L. M., Allen, M. R., Stock, J. L., Duman, R. S., McNeish, J. D., Barrot, M., Self, D. W., Nestler, E. J. & Schaeffer, E., Apr 25 2003, In : Brain Research. 970, 1-2, p. 73-86 14 p.

Research output: Contribution to journalArticle

74 Scopus citations

Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments

Hope, B. T., Nye, H. E., Kelz, M. B., Self, D. W., Iadarola, M. J., Nakabeppu, Y., Duman, R. S. & Nestler, E. J., Nov 1994, In : Neuron. 13, 5, p. 1235-1244 10 p.

Research output: Contribution to journalArticle

462 Scopus citations

Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system

Berhow, M. T., Russell, D. S., Terwilliger, R. Z., Beitner-Johnson, D., Self, D. W., Lindsay, R. M. & Nestler, E. J., Oct 1995, In : Neuroscience. 68, 4, p. 969-979 11 p.

Research output: Contribution to journalArticle

149 Scopus citations

Integrating behavioral and molecular approaches in mouse: Self-administration studies

Graham, D. L. & Self, D. W., Jan 1 2010, Advances in the Neuroscience of Addiction. CRC Press, p. 163-192 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior

Self, D. W., Genova, L. M., Hope, B. T., Barnhart, W. J., Spencer, J. J. & Nestler, E. J., Mar 1 1998, In : Journal of Neuroscience. 18, 5, p. 1848-1859 12 p.

Research output: Contribution to journalArticle

267 Scopus citations

IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates

Russo, S. J., Bolanos, C. A., Theobald, D. E., DeCarolis, N. A., Renthal, W., Kumar, A., Winstanley, C. A., Renthal, N. E., Wiley, M. D., Self, D. W., Russell, D. S., Neve, R. L., Eisch, A. J. & Nestler, E. J., Jan 1 2007, In : Nature neuroscience. 10, 1, p. 93-99 7 p.

Research output: Contribution to journalArticle

143 Scopus citations

It's only a matter of time: longevity of cocaine-induced changes in dendritic spine density in the nucleus accumbens

Anderson, E. M. & Self, D. W., Feb 1 2017, In : Current Opinion in Behavioral Sciences. 13, p. 117-123 7 p.

Research output: Contribution to journalReview article

7 Scopus citations

Knockdown of the histone di-methyltransferase G9a in nucleus accumbens shell decreases cocaine self-administration, stress-induced reinstatement, and anxiety

Anderson, E. M., Sun, H., Guzman, D., Taniguchi, M., Cowan, C. W., Maze, I., Nestler, E. J. & Self, D. W., Jan 1 2018, (Accepted/In press) In : Neuropsychopharmacology.

Research output: Contribution to journalArticle

2 Scopus citations

Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions

Krishnan, V., Han, M. H., Graham, D. L., Berton, O., Renthal, W., Russo, S. J., LaPlant, Q., Graham, A., Lutter, M., Lagace, D. C., Ghose, S., Reister, R., Tannous, P., Green, T. A., Neve, R. L., Chakravarty, S., Kumar, A., Eisch, A. J., Self, D. W., Lee, F. S. & 4 others, Tamminga, C. A., Cooper, D. C., Gershenfeld, H. K. & Nestler, E. J., Oct 19 2007, In : Cell. 131, 2, p. 391-404 14 p.

Research output: Contribution to journalArticle

1105 Scopus citations

Molecular and genetic approaches for behavioral analysis of protein function

Self, D. W., Jun 15 2005, In : Biological Psychiatry. 57, 12, p. 1479-1484 6 p.

Research output: Contribution to journalReview article

4 Scopus citations