• 11461 Citations
  • 49 h-Index
1989 …2018

Research output per year

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Research Output

2004

Drug Dependence and Addiction: Neural Substrates

Self, D. & Tamminga, C. A., Feb 1 2004, In : American Journal of Psychiatry. 161, 2, 1 p.

Research output: Contribution to journalArticle

11 Scopus citations

Erratum: Applications of a rat multiple tissue gene expression data set (Genome Research (2004) vol. 14 (742-749))

Walker, J. R., Su, A. I., Self, D. W., Hogenesch, J. B., Lapp, H., Sturchler, C., Kinnunen, A., Maier, R., Hoyer, D. & Bilbe, G., Jul 1 2004, In : Genome Research. 14, 7, 1 p.

Research output: Contribution to journalComment/debate

Extinction-induced neuroplasticity attenuates stress-induced cocaine seeking: A state-dependent learning hypothesis

Self, D. W. & Choi, K. H., Sep 1 2004, In : Stress. 7, 3, p. 145-155 11 p.

Research output: Contribution to journalReview article

27 Scopus citations

Extinction training regulates neuroadaptive responses to withdrawal from chronic cocaine self-administration

Self, D. W., Choi, K. H., Simmons, D., Walker, J. R. & Smagula, C. S., Sep 1 2004, In : Learning and Memory. 11, 5, p. 648-657 10 p.

Research output: Contribution to journalReview article

95 Scopus citations

Regulation of drug-taking and -seeking behaviors by neuroadaptations in the mesolimbic dopamine system

Self, D. W., Jan 1 2004, In : Neuropharmacology. 47, SUPPL. 1, p. 242-255 14 p.

Research output: Contribution to journalArticle

145 Scopus citations

Stress-induced cigarette craving: Effect of the DRD2 Taql RFLP and SLC6A3 VNTR polymorphims

Erblich, J., Lerman, C., Self, D. W., Diaz, G. A. & Bovbjerg, D. H., Apr 29 2004, In : Pharmacogenomics Journal. 4, 2, p. 102-109 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Testosterone reinforcement: Intravenous and intracerebroventricular self-administration in male rats and hamsters

Wood, R. I., Johnson, L. R., Chu, L., Schad, C. & Self, D. W., Jan 1 2004, In : Psychopharmacology. 171, 3, p. 298-305 8 p.

Research output: Contribution to journalArticle

73 Scopus citations
2003

Extinction-induced upregulation in AMPA receptors reduces cocaine-seeking behaviour

Sutton, M. A., Schmidt, E. F., Choi, K. H., Schad, C. A., Whisler, K., Simmons, D., Karanian, D. A., Monteggia, L. M., Neve, R. L. & Self, D. W., Jan 2 2003, In : Nature. 421, 6918, p. 70-75 6 p.

Research output: Contribution to journalArticle

264 Scopus citations

Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine

Peakman, M. C., Colby, C., Perrotti, L. I., Tekumalla, P., Carle, T., Ulery, P., Chao, J., Duman, C., Steffen, C., Monteggia, L. M., Allen, M. R., Stock, J. L., Duman, R. S., McNeish, J. D., Barrot, M., Self, D. W., Nestler, E. J. & Schaeffer, E., Apr 25 2003, In : Brain Research. 970, 1-2, p. 73-86 14 p.

Research output: Contribution to journalArticle

74 Scopus citations

Neurobiology: Dopamine as chicken and egg

Self, D., Apr 10 2003, In : Nature. 422, 6932, p. 573-574 2 p.

Research output: Contribution to journalShort survey

9 Scopus citations

Opposite Effects of GluR1 and PKA-Resistant GluR1 Overexpression in the Ventral Tegmental Area on Cocaine Reinforcement

Choi, K. H., Rahman, Z., Edwards, S., Hall, S., Neve, R. L. & Self, D. W., Nov 2003, In : Annals of the New York Academy of Sciences. 1003, p. 372-374 3 p.

Research output: Contribution to journalArticle

8 Scopus citations

RGS9 modulates dopamine signaling in the basal ganglia

Rahman, Z., Schwarz, J., Gold, S. J., Zachariou, V., Wein, M. N., Choi, K. H., Kovoor, A., Chen, C. K., DiLeone, R. J., Schwarz, S. C., Selley, D. E., Sim-Selley, L. J., Barrot, M., Luedtke, R. R., Self, D., Neve, R. L., Lester, H. A., Simon, M. I. & Nestler, E. J., Jun 19 2003, In : Neuron. 38, 6, p. 941-952 12 p.

Research output: Contribution to journalArticle

214 Scopus citations

Striatal cell type-specific overexpression of ΔFosB enhances incentive for cocaine

Colby, C. R., Whisler, K., Steffen, C., Nestler, E. J. & Self, D. W., Mar 15 2003, In : Journal of Neuroscience. 23, 6, p. 2488-2493 6 p.

Research output: Contribution to journalArticle

163 Scopus citations
2002
86 Scopus citations

Where's the excitement in psychostimulant sensitization?

Self, D. W., Jan 29 2002, In : Neuropsychopharmacology. 26, 1, p. 14-17 4 p.

Research output: Contribution to journalComment/debate

7 Scopus citations
2001

A neurobiological basis for substance abuse comorbidity in schizophrenia

Chambers, R. A., Krystal, J. H. & Self, D. W., Jul 15 2001, In : Biological Psychiatry. 50, 2, p. 71-83 13 p.

Research output: Contribution to journalReview article

395 Scopus citations

Extinction training regulates tyrosine hydroxylase during withdrawal from cocaine self-administration.

Schmidt, E. F., Sutton, M. A., Schad, C. A., Karanian, D. A., Brodkin, E. S. & Self, D. W., Apr 1 2001, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 21, 7, p. RC137

Research output: Contribution to journalArticle

47 Scopus citations

ΔFosB: A sustained molecular switch for addiction

Nestler, E. J., Barrot, M. & Self, D. W., Sep 25 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 20, p. 11042-11046 5 p.

Research output: Contribution to journalArticle

399 Scopus citations
2000

Effects of the novel D1 dopamine receptor agonist ABT-431 on cocaine self-administration and reinstatement

Self, D. W., Karanian, D. A. & Spencer, J. J., Jan 1 2000, In : Annals of the New York Academy of Sciences. 909, p. 133-144 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

Factors that determine a propensity for cocaine-seeking behavior during abstinence in rats

Sutton, M. A., Kamnian, D. A. & Self, D. W., Jun 1 2000, In : Neuropsychopharmacology. 22, 6, p. 626-641 16 p.

Research output: Contribution to journalArticle

75 Scopus citations

Opiates inhibit neurogenesis in the adult rat hippocampus

Eisch, A. J., Barrot, M., Schad, C. A., Self, D. W. & Nestler, E. J., Jun 20 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 13, p. 7579-7584 6 p.

Research output: Contribution to journalArticle

476 Scopus citations
1999

Anandamide: A candidate neurotransmitter heads for the big leagues

Self, D. W., Apr 1 1999, In : Nature neuroscience. 2, 4, p. 303-304 2 p.

Research output: Contribution to journalShort survey

20 Scopus citations

Comparison of transgenic strategies for behavioral neuroscience studies in rodents

Self, D. W., Dec 1 1999, In : Psychopharmacology. 147, 1, p. 35-37 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine

Kelz, M. B., Chen, J., Carlezon, W. A., Whisler, K., Gilden, L., Beckmann, A. M., Steffen, C., Zhang, Y. J., Marotti, L., Self, D. W., Tkatch, T., Baranauskas, G., Surmeler, D. J., Neve, R. L., Duman, R. S., Picciotto, M. R. & Nestler, E. J., Sep 16 1999, In : Nature. 401, 6750, p. 272-276 5 p.

Research output: Contribution to journalArticle

491 Scopus citations

Testing the genetics of behavior in mice [3] (multiple letters)

Picciotto, M. R., Self, D. W., Pohorecky, L. A., Dawson, G. R., Flint, J., Wilkinson, L. S., Hen, R., Tordoff, M. G., Bachmanov, A. A., Friedman, M. I., Beauchamp, G. K., Wahlsten, D., Crabbe, J. & Dudek, B., Oct 5 1999, In : Science. 285, 5436, p. 2067-2070 4 p.

Research output: Contribution to journalLetter

2 Scopus citations
1998

Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior

Self, D. W., Genova, L. M., Hope, B. T., Barnhart, W. J., Spencer, J. J. & Nestler, E. J., Mar 1 1998, In : Journal of Neuroscience. 18, 5, p. 1848-1859 12 p.

Research output: Contribution to journalArticle

267 Scopus citations

Neural substrates of drug craving and relapse in drug addiction

Self, D. W., Jan 1 1998, In : Annals of Medicine. 30, 4, p. 379-389 11 p.

Research output: Contribution to journalReview article

105 Scopus citations

Relapse to drug-seeking: Neural and molecular mechanisms

Self, D. W. & Nestler, E. J., Jun 1 1998, In : Drug and Alcohol Dependence. 51, 1-2, p. 49-60 12 p.

Research output: Contribution to journalArticle

243 Scopus citations
1997

Opposite modulation of opiate withdrawal behaviors on microinfusion of a protein kinase A inhibitor versus activator into the locus coeruleus or periaqueductal gray

Punch, L. J., Self, D. W., Nestler, E. J. & Taylor, J. R., Nov 6 1997, In : Journal of Neuroscience. 17, 21, p. 8520-8527 8 p.

Research output: Contribution to journalArticle

112 Scopus citations
1996

Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonists

Self, D. W., Barnhart, W. J., Lehman, D. A. & Nestler, E. J., Jan 1 1996, In : Science. 271, 5255, p. 1586-1589 4 p.

Research output: Contribution to journalArticle

423 Scopus citations

Regulation of CREB expression: In vivo evidence for a functional role in morphine action in the nucleus accumbens

Widnell, K. L., Self, D. W., Lane, S. B., Russell, D. S., Vaidya, V. A., Miserendino, M. J. D., Rubin, C. S., Duman, R. S. & Nestler, E. J., Jan 1 1996, In : Journal of Pharmacology and Experimental Therapeutics. 276, 1, p. 306-315 10 p.

Research output: Contribution to journalArticle

137 Scopus citations

Self-administration of the D1 agonist SKF 82958 is mediated by D1, not D2, receptors

Self, D. W., Belluzzi, J. D., Kossuth, S. & Stein, L., Mar 11 1996, In : Psychopharmacology. 123, 4, p. 303-306 4 p.

Research output: Contribution to journalArticle

45 Scopus citations
1995

Biochemical adaptations in the mesolimbic dopamine system in response to heroin self‐administration

Self, D. W., McClenahan, A. W., Beitner-Johnson, D., Terwilliger, R. Z. & Nestler, E. J., Dec 1995, In : Synapse. 21, 4, p. 312-318 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Cocaine abuse takes a shot

Self, D. W., Dec 14 1995, In : Nature. 378, 6558, p. 666-667 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system

Berhow, M. T., Russell, D. S., Terwilliger, R. Z., Beitner-Johnson, D., Self, D. W., Lindsay, R. M. & Nestler, E. J., Oct 1995, In : Neuroscience. 68, 4, p. 969-979 11 p.

Research output: Contribution to journalArticle

149 Scopus citations

Molecular mechanisms of drug reinforcement and addiction

Self, D. W. & Nestler, E. J., Jan 1 1995, In : Annual Review of Neuroscience. 18, p. 463-495 33 p.

Research output: Contribution to journalReview article

470 Scopus citations
1994

Inactivation of G(i) and G(o) proteins in nucleus accumbens reduces both cocaine and heroin reinforcement

Self, D. W., Terwilliger, R. Z., Nestler, E. J. & Stein, L., Jan 1 1994, In : Journal of Neuroscience. 14, 10, p. 6239-6247 9 p.

Research output: Contribution to journalArticle

90 Scopus citations

Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments

Hope, B. T., Nye, H. E., Kelz, M. B., Self, D. W., Iadarola, M. J., Nakabeppu, Y., Duman, R. S. & Nestler, E. J., Nov 1994, In : Neuron. 13, 5, p. 1235-1244 10 p.

Research output: Contribution to journalArticle

462 Scopus citations
1993

Effects of D1 and D2-selective antagonists on self-administration of the D1 agonist SKF 82958

Self, D. W., Lam, D. M., Kossuth, S. R. & Stein, L., Jan 1 1993, In : NIDA Research Monograph Series. 132, 1 p.

Research output: Contribution to journalArticle

4 Scopus citations

Pertussis toxin attenuates intracranial morphine self-administration

Self, D. W. & Stein, L., Nov 1993, In : Pharmacology, Biochemistry and Behavior. 46, 3, p. 689-695 7 p.

Research output: Contribution to journalArticle

22 Scopus citations
1992

Receptor Subtypes in Opioid and Stimulant Reward

Self, D. W. & Stein, L., Feb 1992, In : Pharmacology & Toxicology. 70, 2, p. 87-94 8 p.

Research output: Contribution to journalArticle

64 Scopus citations

The D1 agonists SKF 82958 and SKF 77434 are self-administered by rats

Self, D. W. & Stein, L., Jun 12 1992, In : Brain Research. 582, 2, p. 349-352 4 p.

Research output: Contribution to journalArticle

121 Scopus citations
1989

Coupling of subtypes of the muscarinic receptor to adenylate cyclase in the corpus striatum and heart

Ehlert, F. J., Delen, F. M., Yun, S. H., Friedman, D. J. & Self, D. W., Jan 1 1989, In : Journal of Pharmacology and Experimental Therapeutics. 251, 2, p. 660-671 12 p.

Research output: Contribution to journalArticle

29 Scopus citations