• 11461 Citations
  • 49 h-Index
1989 …2018

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Molecular mechanisms of drug reinforcement and addiction

Self, D. W. & Nestler, E. J., Jan 1 1995, In : Annual Review of Neuroscience. 18, p. 463-495 33 p.

Research output: Contribution to journalReview article

470 Scopus citations

Monogamy: Dopamine ties the knot

Edwards, S. & Self, D. W., Jan 1 2006, In : Nature neuroscience. 9, 1, p. 7-8 2 p.

Research output: Contribution to journalShort survey

19 Scopus citations
86 Scopus citations

Neural substrates of drug craving and relapse in drug addiction

Self, D. W., Jan 1 1998, In : Annals of Medicine. 30, 4, p. 379-389 11 p.

Research output: Contribution to journalReview article

105 Scopus citations

Neurobiology: Dopamine as chicken and egg

Self, D., Apr 10 2003, In : Nature. 422, 6932, p. 573-574 2 p.

Research output: Contribution to journalShort survey

9 Scopus citations

Opiates inhibit neurogenesis in the adult rat hippocampus

Eisch, A. J., Barrot, M., Schad, C. A., Self, D. W. & Nestler, E. J., Jun 20 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 13, p. 7579-7584 6 p.

Research output: Contribution to journalArticle

476 Scopus citations

Opposite Effects of GluR1 and PKA-Resistant GluR1 Overexpression in the Ventral Tegmental Area on Cocaine Reinforcement

Choi, K. H., Rahman, Z., Edwards, S., Hall, S., Neve, R. L. & Self, D. W., Nov 2003, In : Annals of the New York Academy of Sciences. 1003, p. 372-374 3 p.

Research output: Contribution to journalArticle

8 Scopus citations

Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonists

Self, D. W., Barnhart, W. J., Lehman, D. A. & Nestler, E. J., Jan 1 1996, In : Science. 271, 5255, p. 1586-1589 4 p.

Research output: Contribution to journalArticle

423 Scopus citations

Opposite modulation of opiate withdrawal behaviors on microinfusion of a protein kinase A inhibitor versus activator into the locus coeruleus or periaqueductal gray

Punch, L. J., Self, D. W., Nestler, E. J. & Taylor, J. R., Nov 6 1997, In : Journal of Neuroscience. 17, 21, p. 8520-8527 8 p.

Research output: Contribution to journalArticle

112 Scopus citations

Optogenetic stimulation of accumbens shell or shell projections to lateral hypothalamus produce differential effects on the motivation for cocaine

Larson, E. B., Wissman, A. M., Loriaux, A. L., Kourrich, S. & Self, D. W., Jan 1 2015, In : Journal of Neuroscience. 35, 8, p. 3537-3543 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats

Larson, E. B., Graham, D. L., Arzaga, R. R., Buzin, N., Webb, J., Green, T. A., Bass, C. E., Neve, R. L., Terwilliger, E. F., Nestler, E. J. & Self, D. W., Nov 9 2011, In : Journal of Neuroscience. 31, 45, p. 16447-16457 11 p.

Research output: Contribution to journalArticle

70 Scopus citations

Overexpression of the histone dimethyltransferase G9a in nucleus accumbens shell increases cocaine self-administration, stress-induced reinstatement, and anxiety

Anderson, E. M., Larson, E. B., Guzman, D., Wissman, A. M., Neve, R. L., Nestler, E. J. & Self, D. W., Jan 24 2018, In : Journal of Neuroscience. 38, 4, p. 803-813 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Pertussis toxin attenuates intracranial morphine self-administration

Self, D. W. & Stein, L., Nov 1993, In : Pharmacology, Biochemistry and Behavior. 46, 3, p. 689-695 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Phosphorylation of GluR1, ERK, and CREB during spontaneous withdrawal from chronic heroin self-administration

Edwards, S., Graham, D. L., Whisler, K. N. & Self, D. W., Mar 2009, In : Synapse. 63, 3, p. 224-235 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Preface

Self, D. W. & Staley, J. K., 2010, In : Current Topics in Behavioral Neurosciences. 2010, 3, p. 5-6 2 p.

Research output: Contribution to journalArticle

Receptor Subtypes in Opioid and Stimulant Reward

Self, D. W. & Stein, L., Feb 1992, In : Pharmacology & Toxicology. 70, 2, p. 87-94 8 p.

Research output: Contribution to journalArticle

64 Scopus citations

Region-specific tolerance to cocaine-regulated cAMP-dependent protein phosphorylation following chronic self-administration

Edwards, S., Graham, D. L., Bachtell, R. K. & Self, D. W., Apr 1 2007, In : European Journal of Neuroscience. 25, 7, p. 2201-2213 13 p.

Research output: Contribution to journalArticle

54 Scopus citations

Regulation of CREB expression: In vivo evidence for a functional role in morphine action in the nucleus accumbens

Widnell, K. L., Self, D. W., Lane, S. B., Russell, D. S., Vaidya, V. A., Miserendino, M. J. D., Rubin, C. S., Duman, R. S. & Nestler, E. J., Jan 1 1996, In : Journal of Pharmacology and Experimental Therapeutics. 276, 1, p. 306-315 10 p.

Research output: Contribution to journalArticle

137 Scopus citations

Regulation of drug reward by cAMP response element-binding protein: Evidence for two functionally distinct subregions of the ventral tegmental area

Olson, V. G., Zabetian, C. P., Bolanos, C. A., Edwards, S., Barrot, M., Eisch, A. J., Hughes, T., Self, D. W., Neve, R. L. & Nestler, E. J., Jun 8 2005, In : Journal of Neuroscience. 25, 23, p. 5553-5562 10 p.

Research output: Contribution to journalArticle

159 Scopus citations

Regulation of drug-taking and -seeking behaviors by neuroadaptations in the mesolimbic dopamine system

Self, D. W., Jan 1 2004, In : Neuropharmacology. 47, SUPPL. 1, p. 242-255 14 p.

Research output: Contribution to journalArticle

145 Scopus citations

Reinforcement-related regulation of AMPA glutamate receptor subunits in the ventral tegmental area enhances motivation for cocaine

Choi, K. H., Edwards, S., Graham, D. L., Larson, E. B., Whisler, K. N., Simmons, D., Friedman, A. K., Walsh, J. J., Rahman, Z., Monteggia, L. M., Eisch, A. J., Neve, R. L., Nestler, E. J., Han, M. H. & Self, D. W., May 25 2011, In : Journal of Neuroscience. 31, 21, p. 7927-7937 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Relapse to drug-seeking: Neural and molecular mechanisms

Self, D. W. & Nestler, E. J., Jun 1 1998, In : Drug and Alcohol Dependence. 51, 1-2, p. 49-60 12 p.

Research output: Contribution to journalArticle

243 Scopus citations

Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA receptor-mediated behavior

Bachtell, R. K. & Self, D. W., Nov 26 2008, In : Journal of Neuroscience. 28, 48, p. 12808-12814 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

RGS9 modulates dopamine signaling in the basal ganglia

Rahman, Z., Schwarz, J., Gold, S. J., Zachariou, V., Wein, M. N., Choi, K. H., Kovoor, A., Chen, C. K., DiLeone, R. J., Schwarz, S. C., Selley, D. E., Sim-Selley, L. J., Barrot, M., Luedtke, R. R., Self, D., Neve, R. L., Lester, H. A., Simon, M. I. & Nestler, E. J., Jun 19 2003, In : Neuron. 38, 6, p. 941-952 12 p.

Research output: Contribution to journalArticle

214 Scopus citations

Role of GluR1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine-seeking behavior

Bachtell, R. K., Choi, K. H., Simmons, D. L., Falcon, E., Monteggia, L. M., Neve, R. L. & Self, D. W., May 1 2008, In : European Journal of Neuroscience. 27, 9, p. 2229-2240 12 p.

Research output: Contribution to journalArticle

60 Scopus citations

Role of Mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior

Simmons, D. & Self, D. W., Jul 1 2009, In : Neuropsychopharmacology. 34, 8, p. 1946-1957 12 p.

Research output: Contribution to journalArticle

56 Scopus citations

Self-administration of the D1 agonist SKF 82958 is mediated by D1, not D2, receptors

Self, D. W., Belluzzi, J. D., Kossuth, S. & Stein, L., Mar 11 1996, In : Psychopharmacology. 123, 4, p. 303-306 4 p.

Research output: Contribution to journalArticle

45 Scopus citations

Stress-induced cigarette craving: Effect of the DRD2 Taql RFLP and SLC6A3 VNTR polymorphims

Erblich, J., Lerman, C., Self, D. W., Diaz, G. A. & Bovbjerg, D. H., Apr 29 2004, In : Pharmacogenomics Journal. 4, 2, p. 102-109 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Stress-related receptor targets for cocaine addiction

Self, D. W., Aug 1 2010, In : Biological Psychiatry. 68, 3, p. 217-218 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Striatal cell type-specific overexpression of ΔFosB enhances incentive for cocaine

Colby, C. R., Whisler, K., Steffen, C., Nestler, E. J. & Self, D. W., Mar 15 2003, In : Journal of Neuroscience. 23, 6, p. 2488-2493 6 p.

Research output: Contribution to journalArticle

163 Scopus citations

Striatal regulation of ΔfosB, FosB, and cFos during cocaine self-administration and withdrawal

Larson, E. B., Akkentli, F., Edwards, S., Graham, D. L., Simmons, D. L., Alibhai, I. N., Nestler, E. J. & Self, D. W., Oct 1 2010, In : Journal of Neurochemistry. 115, 1, p. 112-122 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

Striatal signal transduction and drug addiction

Philibin, S. D., Hernandez, A., Self, D. W. & Bibb, J. A., Dec 1 2011, In : Frontiers in Neuroanatomy. SEP

Research output: Contribution to journalReview article

22 Scopus citations

Testing the genetics of behavior in mice [3] (multiple letters)

Picciotto, M. R., Self, D. W., Pohorecky, L. A., Dawson, G. R., Flint, J., Wilkinson, L. S., Hen, R., Tordoff, M. G., Bachmanov, A. A., Friedman, M. I., Beauchamp, G. K., Wahlsten, D., Crabbe, J. & Dudek, B., Oct 5 1999, In : Science. 285, 5436, p. 2067-2070 4 p.

Research output: Contribution to journalLetter

2 Scopus citations

Testosterone reinforcement: Intravenous and intracerebroventricular self-administration in male rats and hamsters

Wood, R. I., Johnson, L. R., Chu, L., Schad, C. & Self, D. W., Jan 1 2004, In : Psychopharmacology. 171, 3, p. 298-305 8 p.

Research output: Contribution to journalArticle

73 Scopus citations

The D1 agonists SKF 82958 and SKF 77434 are self-administered by rats

Self, D. W. & Stein, L., Jun 12 1992, In : Brain Research. 582, 2, p. 349-352 4 p.

Research output: Contribution to journalArticle

121 Scopus citations

Tropomyosin-Related Kinase B in the Mesolimbic Dopamine System: Region-Specific Effects on Cocaine Reward

Graham, D. L., Krishnan, V., Larson, E. B., Graham, A., Edwards, S., Bachtell, R. K., Simmons, D., Gent, L. M., Berton, O., Bolanos, C. A., DiLeone, R. J., Parada, L. F., Nestler, E. J. & Self, D. W., Apr 15 2009, In : Biological Psychiatry. 65, 8, p. 696-701 6 p.

Research output: Contribution to journalArticle

84 Scopus citations

Where's the excitement in psychostimulant sensitization?

Self, D. W., Jan 29 2002, In : Neuropsychopharmacology. 26, 1, p. 14-17 4 p.

Research output: Contribution to journalComment/debate

7 Scopus citations

Withdrawal from cocaine self-administration normalizes deficits in proliferation and enhances maturity of adult-generated hippocampal neurons

Noonan, M. A., Choi, K. H., Self, D. W. & Eisch, A. J., Mar 5 2008, In : Journal of Neuroscience. 28, 10, p. 2516-2526 11 p.

Research output: Contribution to journalArticle

84 Scopus citations

ΔFosB: A sustained molecular switch for addiction

Nestler, E. J., Barrot, M. & Self, D. W., Sep 25 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 20, p. 11042-11046 5 p.

Research output: Contribution to journalArticle

399 Scopus citations

ΔFosB accumulates in a GABAergic cell population in the posterior tail of the ventral tegmental area after psychostimulant treatment

Perrotti, L. I., Bolaños, C. A., Choi, K. H., Russo, S. J., Edwards, S., Ulery, P. G., Wallace, D. L., Self, D. W., Nestler, E. J. & Barrot, M., May 1 2005, In : European Journal of Neuroscience. 21, 10, p. 2817-2824 8 p.

Research output: Contribution to journalArticle

129 Scopus citations

ΔFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction

Winstanley, C. A., LaPlant, Q., Theobald, D. E. H., Green, T. A., Bachtell, R. K., Perrotti, L. I., DiLeone, R. J., Russo, S. J., Garth, W. J., Self, D. W. & Nestler, E. J., Sep 26 2007, In : Journal of Neuroscience. 27, 39, p. 10497-10507 11 p.

Research output: Contribution to journalArticle

105 Scopus citations

ΔFosB induction in striatal medium spiny neuron subtypes in response to chronic pharmacological, emotional, and optogenetic stimuli

Lobo, M. K., Zaman, S., Damez-Werno, D. M., Koo, J. W., Bagot, R. C., DiNieri, J. A., Nugent, A., Finkel, E., Chaudhury, D., Chandra, R., Riberio, E., Rabkin, J., Mouzon, E., Cachope, R., Cheer, J. F., Han, M. H., Dietz, D. M., Self, D. W., Hurd, Y. L., Vialou, V. & 1 others, Nestler, E. J., Nov 22 2013, In : Journal of Neuroscience. 33, 47, p. 18381-18395 15 p.

Research output: Contribution to journalArticle

121 Scopus citations