• 9195 Citations
  • 53 h-Index
1969 …2018

Research output per year

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Research Output

2018

Antibody biomarker for de novo Parkinson disease: attempted validation

Feng, N., Simanski, S., Islam, K., Hynan, L. S., Kodadek, T. & German, D. C., Dec 1 2018, In : npj Parkinson's Disease. 4, 1, 28.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2017

Parkinson's disease biomarkers: Perspective from the NINDS Parkinson's Disease Biomarkers Program

Gwinn, K., David, K. K., Swanson-Fischer, C., Albin, R., Hillaire-Clarke, C. S., Sieber, B. A., Lungu, C., Bowman, F. D., Alcalay, R. N., Babcock, D., Dawson, T. M., Dewey, R. B., Foroud, T., German, D., Huang, X., Petyuk, V., Potashkin, J. A., Saunders-Pullman, R., Sutherland, M., Walt, D. R. & 6 others, West, A. B., Zhang, J., Chen-Plotkin, A., Scherzer, C. R., Vaillancourt, D. E. & Rosenthal, L. S., Jun 1 2017, In : Biomarkers in Medicine. 11, 6, p. 451-473 23 p.

Research output: Contribution to journalReview article

18 Scopus citations

Serum thyroid-stimulating hormone and interleukin-8 levels in boys with autism spectrum disorder

Singh, S., Yazdani, U., Gadad, B., Zaman, S., Hynan, L. S., Roatch, N., Schutte, C., Marti, C. N., Hewitson, L. & German, D. C., Jun 2 2017, In : Journal of Neuroinflammation. 14, 1, 113.

Research output: Contribution to journalArticle

9 Scopus citations
2016

A search for blood biomarkers for autism: Peptoids

Zaman, S., Yazdani, U., Deng, Y., Li, W., Gadad, B. S., Hynan, L., Karp, D., Roatch, N., Schutte, C., Nathan Marti, C., Hewitson, L. & German, D. C., Jan 14 2016, In : Scientific Reports. 6, 19164.

Research output: Contribution to journalArticle

14 Scopus citations

Blood biomarker for Parkinson disease: peptoids

Yazdani, U., Zaman, S., Hynan, L. S., Brown, L. S., Dewey, R. B., Karp, D. & German, D. C., Dec 1 2016, In : npj Parkinson's Disease. 2, 1, 16012.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2015

Administration of thimerosal-containing vaccines to infant rhesus macaques does not result in autism-like behavior or neuropathology

Gadad, B. S., Li, W., Yazdani, U., Grady, S., Johnson, T., Hammond, J., Gunn, H., Curtis, B., English, C., Yutuc, V., Ferrier, C., Sackett, G. P., Marti, C. N., Young, K., Hewitson, L. & German, D. C., Oct 6 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 40, p. 12498-12503 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Erratum: Administration of thimerosal-containing vaccines to infant rhesus macaques does not result in autism-like behavior or neuropathology (Proceedings of the National Academy of Sciences of the United States of America (2015) 112: (12498-12503) DOI: 10.1073/pnas.1500968112)

Gadad, B. S., Li, W., Yazdani, U., Grady, S., Johnson, T., Hammond, J., Gunn, H., Curtis, B., English, C., Yutuc, V., Ferrier, C., Sackett, G. P., Marti, C. N., Young, K., Hewitson, L. & German, D. C., Dec 8 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 49, p. E6827

Research output: Contribution to journalArticle

Klotho protects dopaminergic neuron oxidant-induced degeneration by modulating ASK1 and p38 MAPK signaling pathways

Brobey, R. K., German, D., Sonsalla, P. K., Gurnani, P., Pastor, J., Hsieh, C. C., Papaconstantinou, J., Foster, P. P., Kuro-O, M. & Rosenblatt, K. P., Oct 9 2015, In : PloS one. 10, 10, e0139914.

Research output: Contribution to journalArticle

28 Scopus citations

The NINDS Parkinson's disease biomarkers program

Rosenthal, L. S., Drake, D., Alcalay, R. N., Babcock, D., Bowman, F. D., Chen-Plotkin, A., Dawson, T. M., Dewey, R. B., German, D. C., Huang, X., Landin, B., Mcauliffe, M., Petyuk, V. A., Scherzer, C. R., Hillaire-Clarke, C. S., Sieber, B. A., Sutherland, M., Tarn, C., West, A., Vaillancourt, D. & 2 others, Zhang, J. & Gwinn, K., 2015, (Accepted/In press) In : Movement Disorders.

Research output: Contribution to journalArticle

34 Scopus citations
2014

Alzheimer disease risk factors

Richardson, J. R., German, D. & Levey, A., Aug 2014, In : JAMA neurology. 71, 8, 1 p.

Research output: Contribution to journalLetter

3 Scopus citations

Beta-amyloid auto-antibodies are reduced in Alzheimer's disease

Qu, B. X., Gong, Y., Moore, C., Fu, M., German, D. C., Chang, L. Y., Rosenberg, R. & Diaz-Arrastia, R., Jan 1 2014, In : Journal of Neuroimmunology. 274, 1-2, p. 168-173 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Discovery of biomarkers for systemic lupus erythematosus using a library of synthetic autoantigen surrogates

Quan, J., Lakhanpal, A., Reddy, M. M., Zaman, S., Li, Q. Z., German, D. C., Olsen, N. J., Kodadek, T. & Karp, D. R., Jan 1 2014, In : Journal of Immunological Methods. 402, 1-2, p. 23-34 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Discovery of biomarkers for systemic lupus erythematosus using a library of synthetic autoantigen surrogates.

Quan, J., Lakhanpal, A., Reddy, M. M., Zaman, S., Li, Q. Z., German, D. C., Olsen, N. J., Kodadek, T. & Karp, D. R., 2014, Journal of immunological methods. 1-2 ed. Vol. 402. p. 23-34 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Elevated serum DDE and risk for Alzheimer disease: In reply

Richardson, J. R., Levey, A. I. & German, D. C., Aug 2014, In : JAMA neurology. 71, 8, 1 p.

Research output: Contribution to journalLetter

Elevated serum pesticide levels and risk for Alzheimer disease

Richardson, J. R., Roy, A., Shalat, S. L., Von Stein, R. T., Hossain, M. M., Buckley, B., Gearing, M., Levey, A. I. & German, D. C., Mar 2014, In : JAMA neurology. 71, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

103 Scopus citations

Validation of a serum screen for alzheimer's disease across assay platforms, species, and tissues

O'Bryant, S. E., Xiao, G., Zhang, F., Edwards, M., German, D. C., Yin, X., Como, T., Reisch, J., Huebinger, R. M., Graff-Radford, N., Dickson, D., Barber, R., Hall, J., O'Suilleabhain, P. & Grammas, P., Jan 1 2014, In : Journal of Alzheimer's Disease. 42, 4, p. 1325-1335 11 p.

Research output: Contribution to journalArticle

41 Scopus citations
2013

The angiotensin converting enzyme inhibitor captopril protects nigrostriatal dopamine neurons in animal models of parkinsonism

Sonsalla, P. K., Coleman, C., Wong, L. Y., Harris, S. L., Richardson, J. R., Gadad, B. S., Li, W. & German, D. C., Dec 1 2013, In : Experimental Neurology. 250, p. 376-383 8 p.

Research output: Contribution to journalArticle

40 Scopus citations
2012

Apoptosis signal-regulating kinase 1 mediates MPTP toxicity and regulates glial activation

Lee, K. W., Zhao, X., Im, J. Y., Grosso, H., Jang, W. H., Chan, T. W., Sonsalla, P. K., German, D. C., Ichijo, H., Junn, E. & Mouradian, M. M., Jan 10 2012, In : PloS one. 7, 1, e29935.

Research output: Contribution to journalArticle

47 Scopus citations

Delayed caffeine treatment prevents nigral dopamine neuron loss in a progressive rat model of Parkinson's disease

Sonsalla, P. K., Wong, L. Y., Harris, S. L., Richardson, J. R., Khobahy, I., Li, W., Gadad, B. S. & German, D. C., Apr 1 2012, In : Experimental Neurology. 234, 2, p. 482-487 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

Nuclear localization of Klotho in brain: An anti-aging protein

German, D. C., Khobahy, I., Pastor, J., Kuro-o, M. & Liu, X., Jul 2012, In : Neurobiology of Aging. 33, 7, p. 1483.e25-1483.e30

Research output: Contribution to journalArticle

41 Scopus citations

Parkinson's disease: A role for the immune system

German, D. C., Eagar, T. & Sonsalla, P. K., Dec 1 2012, In : Current Molecular Pharmacology. 5, 3, p. 340-349 10 p.

Research output: Contribution to journalReview article

3 Scopus citations
2011

Identification of candidate IgG biomarkers for alzheimer's disease via combinatorial library screening

Reddy, M. M., Wilson, R., Wilson, J., Connell, S., Gocke, A., Hynan, L., German, D. & Kodadek, T., Jan 7 2011, In : Cell. 144, 1, p. 132-142 11 p.

Research output: Contribution to journalArticle

150 Scopus citations

β-Hexachlorocyclohexane levels in serum and risk of Parkinson's disease

Richardson, J. R., Roy, A., Shalat, S. L., Buckley, B., Winnik, B., Gearing, M., Levey, A. I., Factor, S. A., O'Suilleabhain, P. & German, D. C., Oct 1 2011, In : NeuroToxicology. 32, 5, p. 640-645 6 p.

Research output: Contribution to journalArticle

34 Scopus citations
2009

A stereotactic near-infrared probe for localization during functional neurosurgical procedures: Further experience - Clinical article

Giller, C. A., Liu, H., German, D. C., Kashyap, D. & Dewey, R. B., Feb 1 2009, In : Journal of neurosurgery. 110, 2, p. 263-273 11 p.

Research output: Contribution to journalArticle

37 Scopus citations

Elevated serum pesticide levels and risk of Parkinson disease

Richardson, J. R., Shalat, S. L., Buckley, B., Winnik, B., O'Suilleabhain, P., Diaz-Arrastia, R., Reisch, J. & German, D. C., Jul 1 2009, In : Archives of neurology. 66, 7, p. 870-875 6 p.

Research output: Contribution to journalArticle

80 Scopus citations
2008

Acute and Chronic Administration of 1-Methyl-4-Phenylpyridinium

Sonsalla, P. K., Zeevalk, G. D. & German, D. C., Dec 1 2008, Parkinson's Disease. Elsevier Inc., p. 159-172 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Chronic intraventricular administration of 1-methyl-4-phenylpyridinium as a progressive model of Parkinson's disease

Sonsalla, P. K., Zeevalk, G. D. & German, D. C., Jul 1 2008, In : Parkinsonism and Related Disorders. 14, SUPPL.2, p. S116-S118

Research output: Contribution to journalReview article

13 Scopus citations

Major depression, 5HTTLPR genotype, suicide and antidepressant influences on thalamic volume

Young, K. A., Bonkale, W. L., Holcomb, L. A., Hicks, P. B. & German, D. C., Apr 1 2008, In : British Journal of Psychiatry. 192, 4, p. 285-289 5 p.

Research output: Contribution to journalArticle

32 Scopus citations
2007

5HTTLPR Polymorphism and Enlargement of the Pulvinar: Unlocking the Backdoor to the Limbic System

Young, K. A., Holcomb, L. A., Bonkale, W. L., Hicks, P. B., Yazdani, U. & German, D. C., Mar 15 2007, In : Biological Psychiatry. 61, 6, p. 813-818 6 p.

Research output: Contribution to journalArticle

49 Scopus citations

A robust biomarker discovery pipeline for high-performance mass spectrometry data

Fisher, W. G., Rosenblatt, K. P., Fishman, D. A., Whitteley, G. R., Mikulskis, A., Kuzdzal, S. A., Lopez, M. F., Tan, N. C., German, D. C. & Garner, H. R., Oct 1 2007, In : Journal of Bioinformatics and Computational Biology. 5, 5, p. 1023-1045 23 p.

Research output: Contribution to journalArticle

8 Scopus citations

Mitochondria mass is low in mouse substantia nigra dopamine neurons: Implications for Parkinson's disease

Liang, C. L., Wang, T. T., Luby-Phelps, K. & German, D. C., Feb 1 2007, In : Experimental Neurology. 203, 2, p. 370-380 11 p.

Research output: Contribution to journalArticle

127 Scopus citations

Mouse models of alzheimer's disease

German, D. C., Dec 1 2007, Abeta Peptide and Alzheimer's Disease: Celebrating a Century of Research. Springer London, p. 259-273 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Serum biomarkers for Alzheimer's disease: Proteomic discovery

German, D. C., Gurnani, P., Nandi, A., Garner, H. R., Fisher, W., Diaz-Arrastia, R., O'Suilleabhain, P. & Rosenblatt, K. P., Aug 1 2007, In : Biomedicine and Pharmacotherapy. 61, 7, p. 383-389 7 p.

Research output: Contribution to journalArticle

48 Scopus citations
2006

Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease

Donovan, M. H., Yazdani, U., Norris, R. D., Games, D., German, D. C. & Eisch, A. J., Mar 1 2006, In : Journal of Comparative Neurology. 495, 1, p. 70-83 14 p.

Research output: Contribution to journalArticle

287 Scopus citations

Rat model of Parkinson's disease: Chronic central delivery of 1-methyl-4-phenylpyridinium (MPP+)

Yazdani, U., German, D. C., Liang, C. L., Manzino, L., Sonsalla, P. K. & Zeevalk, G. D., Jul 1 2006, In : Experimental Neurology. 200, 1, p. 172-183 12 p.

Research output: Contribution to journalArticle

53 Scopus citations
2005

Determination of reduced scattering coefficient of biological tissue from a needle-like probe

Johns, M., Giller, C. A., German, D. C. & Liu, H., Jun 27 2005, In : Optics Express. 13, 13, p. 4828-4842 15 p.

Research output: Contribution to journalArticle

90 Scopus citations

Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease

Li, H., Repa, J. J., Valasek, M. A., Beltroy, E. P., Turley, S. D., German, D. C. & Dietschy, J. M., Apr 2005, In : Journal of neuropathology and experimental neurology. 64, 4, p. 323-333 11 p.

Research output: Contribution to journalArticle

Open Access
95 Scopus citations
2004

Double-knockout mice for α- and β-synucleins: Effect on synaptic functions

Chandra, S., Fornai, F., Kwon, H. B., Yazdani, U., Atasoy, D., Liu, X., Hammer, R. E., Battaglia, G., German, D. C., Castillo, P. E. & Südhof, T. C., Oct 12 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 41, p. 14966-14971 6 p.

Research output: Contribution to journalArticle

287 Scopus citations

Elevated neuron number in the limbic thalamus in major depression

Young, K. A., Holcomb, L. A., Yazdani, U., Hicks, P. B. & German, D. C., Jul 1 2004, In : American Journal of Psychiatry. 161, 7, p. 1270-1277 8 p.

Research output: Contribution to journalArticle

112 Scopus citations

Inverse Relationship between the Contents of Neuromelanin Pigment and the Vesicular Monoamine Transporter-2: Human Midbrain Dopamine Neurons

Liang, C. L., Nelson, O., Yazdani, U., Pasbakhsh, P. & German, D. C., May 17 2004, In : Journal of Comparative Neurology. 473, 1, p. 97-106 10 p.

Research output: Contribution to journalArticle

72 Scopus citations

Mouse models of Alzheimer's disease: Insight into treatment

German, D. C. & Eisch, A. J., Dec 2 2004, In : Reviews in the Neurosciences. 15, 5, p. 353-369 17 p.

Research output: Contribution to journalReview article

107 Scopus citations
2003

Cholinergic neuropathology in a mouse model of Alzheimer's disease

German, D. C., Yazdani, U., Speciale, S. G., Pasbakhsh, P., Games, D. & Liang, C. L., Jul 5 2003, In : Journal of Comparative Neurology. 462, 4, p. 371-381 11 p.

Research output: Contribution to journalArticle

87 Scopus citations

Validation of a near-infrared probe for detection of thin intracranial white matter structures

Giller, C. A., Liu, H., Gurnani, P., Victor, S., Yazdani, U. & German, D. C., Jun 1 2003, In : Journal of neurosurgery. 98, 6, p. 1299-1306 8 p.

Research output: Contribution to journalArticle

38 Scopus citations
2002

Neurodegeneration in the Niemann-Pick C mouse: Glial involvement

German, D. C., Liang, C. L., Song, T., Yazdani, U., Xie, C. & Dietschy, J. M., Feb 14 2002, In : Neuroscience. 109, 3, p. 437-450 14 p.

Research output: Contribution to journalArticle

144 Scopus citations
2001

Degeneration of neurons and glia in the Niemann-Pick C mouse is unrelated to the low-density lipoprotein receptor

German, D. C., Quintero, E. M., Liang, C. L., Xie, C. & Dietschy, J. M., Aug 22 2001, In : Neuroscience. 105, 4, p. 999-1005 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease

German, D. C., Matthew Quintero, E., Liang, C. L., Ng, B., Punia, S., Xie, C. & Dietschy, J. M., May 7 2001, In : Journal of Comparative Neurology. 433, 3, p. 415-425 11 p.

Research output: Contribution to journalArticle

96 Scopus citations
2000
53 Scopus citations
37 Scopus citations

Reduced number of mediodorsal and anterior thalamic neurons in schizophrenia

Young, K. A., Manaye, K. F., Liang, C. L., Hicks, P. B. & German, D. C., Jun 1 2000, In : Biological Psychiatry. 47, 11, p. 944-953 10 p.

Research output: Contribution to journalArticle

225 Scopus citations

Upregulation of estrogen receptors in the forebrain of aromatase knockout (ArKO) mice

Agarwal, V. R., Sinton, C. M., Liang, C. L., Fisher, C., German, D. C. & Simpson, E. R., Apr 25 2000, In : Molecular and Cellular Endocrinology. 162, 1-2, p. 9-16 8 p.

Research output: Contribution to journalArticle

38 Scopus citations