• 9036 Citations
  • 53 h-Index
1969 …2017
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Research Output 1969 2017

  • 9036 Citations
  • 53 h-Index
  • 135 Article
  • 3 Chapter
  • 1 Review article
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Article
2017
8 Citations (Scopus)

Serum thyroid-stimulating hormone and interleukin-8 levels in boys with autism spectrum disorder

Singh, S., Yazdani, U., Gadad, B., Zaman, S., Hynan, L. S., Roatch, N., Schutte, C., Marti, C. N., Hewitson, L. & German, D. C., Jun 2 2017, In : Journal of Neuroinflammation. 14, 1, 113.

Research output: Contribution to journalArticle

Thyrotropin
Interleukin-8
Serum
Proteins
Biomarkers
2016
10 Citations (Scopus)

A search for blood biomarkers for autism: Peptoids

Zaman, S., Yazdani, U., Deng, Y., Li, W., Gadad, B. S., Hynan, L., Karp, D., Roatch, N., Schutte, C., Nathan Marti, C., Hewitson, L. & German, D. C., Jan 14 2016, In : Scientific Reports. 6, 19164.

Research output: Contribution to journalArticle

Peptoids
Autistic Disorder
Biomarkers
Immunoglobulin G
N-substituted Glycines
2015
16 Citations (Scopus)

Administration of thimerosal-containing vaccines to infant rhesus macaques does not result in autism-like behavior or neuropathology

Gadad, B. S., Li, W., Yazdani, U., Grady, S., Johnson, T., Hammond, J., Gunn, H., Curtis, B., English, C., Yutuc, V., Ferrier, C., Sackett, G. P., Marti, C. N., Young, K., Hewitson, L. & German, D. C., Oct 6 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 40, p. 12498-12503 6 p.

Research output: Contribution to journalArticle

Thimerosal
Autistic Disorder
Macaca mulatta
Vaccines
Measles-Mumps-Rubella Vaccine

Erratum: Administration of thimerosal-containing vaccines to infant rhesus macaques does not result in autism-like behavior or neuropathology (Proceedings of the National Academy of Sciences of the United States of America (2015) 112: (12498-12503) DOI: 10.1073/pnas.1500968112)

Gadad, B. S., Li, W., Yazdani, U., Grady, S., Johnson, T., Hammond, J., Gunn, H., Curtis, B., English, C., Yutuc, V., Ferrier, C., Sackett, G. P., Marti, C. N., Young, K., Hewitson, L. & German, D. C., Dec 8 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 49, p. E6827

Research output: Contribution to journalArticle

27 Citations (Scopus)

Klotho protects dopaminergic neuron oxidant-induced degeneration by modulating ASK1 and p38 MAPK signaling pathways

Brobey, R. K., German, D., Sonsalla, P. K., Gurnani, P., Pastor, J., Hsieh, C. C., Papaconstantinou, J., Foster, P. P., Kuro-O, M. & Rosenblatt, K. P., Oct 9 2015, In : PLoS One. 10, 10, e0139914.

Research output: Contribution to journalArticle

MAP Kinase Kinase Kinase 5
Dopaminergic Neurons
p38 Mitogen-Activated Protein Kinases
mitogen-activated protein kinase
Oxidants
31 Citations (Scopus)

The NINDS Parkinson's disease biomarkers program

Rosenthal, L. S., Drake, D., Alcalay, R. N., Babcock, D., Bowman, F. D., Chen-Plotkin, A., Dawson, T. M., Dewey, R. B., German, D. C., Huang, X., Landin, B., Mcauliffe, M., Petyuk, V. A., Scherzer, C. R., Hillaire-Clarke, C. S., Sieber, B. A., Sutherland, M., Tarn, C., West, A., Vaillancourt, D. & 2 others, Zhang, J. & Gwinn, K., 2015, (Accepted/In press) In : Movement Disorders.

Research output: Contribution to journalArticle

National Institute of Neurological Disorders and Stroke
Parkinson Disease
Biomarkers
Cerebrospinal Fluid
Essential Tremor
2014
3 Citations (Scopus)

Alzheimer disease risk factors

Richardson, J. R., German, D. & Levey, A., 2014, In : JAMA Neurology. 71, 8, p. 1051 1 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Dichlorodiphenyl Dichloroethylene
Insecticides
Alzheimer Disease
14 Citations (Scopus)

Beta-amyloid auto-antibodies are reduced in Alzheimer's disease

Qu, B. X., Gong, Y., Moore, C., Fu, M., German, D. C., Chang, L. Y., Rosenberg, R. & Diaz-Arrastia, R., 2014, In : Journal of Neuroimmunology. 274, 1-2, p. 168-173 6 p.

Research output: Contribution to journalArticle

Amyloid
Alzheimer Disease
Antibodies
Epitopes
Enzyme-Linked Immunosorbent Assay

Elevated serum DDE and risk for Alzheimer disease: In reply

Richardson, J. R., Levey, A. I. & German, D. C., 2014, In : JAMA Neurology. 71, 8, p. 1056 1 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Dichlorodiphenyl Dichloroethylene
Insecticides
Alzheimer Disease
Serum
92 Citations (Scopus)

Elevated serum pesticide levels and risk for Alzheimer disease

Richardson, J. R., Roy, A., Shalat, S. L., Von Stein, R. T., Hossain, M. M., Buckley, B., Gearing, M., Levey, A. I. & German, D. C., Mar 2014, In : JAMA Neurology. 71, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

Pesticides
Alzheimer Disease
Serum
Alleles
Apolipoprotein E4
38 Citations (Scopus)

Validation of a serum screen for alzheimer's disease across assay platforms, species, and tissues

O'Bryant, S. E., Xiao, G., Zhang, F., Edwards, M., German, D. C., Yin, X., Como, T., Reisch, J., Huebinger, R. M., Graff-Radford, N., Dickson, D., Barber, R., Hall, J., O'Suilleabhain, P. & Grammas, P., 2014, In : Journal of Alzheimer's Disease. 42, 4, p. 1325-1335 11 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Serum
Parkinson Disease
Biomarkers
Microvessels
2013
12 Citations (Scopus)

Discovery of biomarkers for systemic lupus erythematosus using a library of synthetic autoantigen surrogates

Quan, J., Lakhanpal, A., Reddy, M. M., Zaman, S., Li, Q. Z., German, D. C., Olsen, N. J., Kodadek, T. & Karp, D. R., 2013, (Accepted/In press) In : Journal of Immunological Methods.

Research output: Contribution to journalArticle

Peptoids
Autoantigens
Systemic Lupus Erythematosus
Biomarkers
Immunoglobulin G
39 Citations (Scopus)

The angiotensin converting enzyme inhibitor captopril protects nigrostriatal dopamine neurons in animal models of parkinsonism

Sonsalla, P. K., Coleman, C., Wong, L. Y., Harris, S. L., Richardson, J. R., Gadad, B. S., Li, W. & German, D. C., Dec 2013, In : Experimental Neurology. 250, p. 376-383 8 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Captopril
Parkinsonian Disorders
Angiotensin-Converting Enzyme Inhibitors
Parkinson Disease
2012
45 Citations (Scopus)

Apoptosis signal-regulating kinase 1 mediates MPTP toxicity and regulates glial activation

Lee, K. W., Zhao, X., Im, J. Y., Grosso, H., Jang, W. H., Chan, T. W., Sonsalla, P. K., German, D. C., Ichijo, H., Junn, E. & Mouradian, M. M., Jan 10 2012, In : PLoS One. 7, 1, e29935.

Research output: Contribution to journalArticle

MAP Kinase Kinase Kinase 5
neuroglia
Neuroglia
Toxicity
phosphotransferases (kinases)
40 Citations (Scopus)

Delayed caffeine treatment prevents nigral dopamine neuron loss in a progressive rat model of Parkinson's disease

Sonsalla, P. K., Wong, L. Y., Harris, S. L., Richardson, J. R., Khobahy, I., Li, W., Gadad, B. S. & German, D. C., Apr 2012, In : Experimental Neurology. 234, 2, p. 482-487 6 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Substantia Nigra
Caffeine
Parkinson Disease
Dopamine
41 Citations (Scopus)

Nuclear localization of Klotho in brain: An anti-aging protein

German, D. C., Khobahy, I., Pastor, J., Kuro-o, M. & Liu, X., Jul 2012, In : Neurobiology of Aging. 33, 7

Research output: Contribution to journalArticle

Choroid Plexus
Purkinje Cells
Nuclear Envelope
Brain
Proteins
3 Citations (Scopus)

Parkinson's disease: A role for the immune system

German, D. C., Eagar, T. & Sonsalla, P. K., 2012, In : Current Molecular Pharmacology. 5, 3, p. 340-349 10 p.

Research output: Contribution to journalArticle

Parkinson Disease
Immune System
Animal Disease Models
Dopaminergic Neurons
Microglia
2011
146 Citations (Scopus)

Identification of candidate IgG biomarkers for alzheimer's disease via combinatorial library screening

Reddy, M. M., Wilson, R., Wilson, J., Connell, S., Gocke, A., Hynan, L., German, D. & Kodadek, T., Jan 7 2011, In : Cell. 144, 1, p. 132-142 11 p.

Research output: Contribution to journalArticle

Biomarkers
Alzheimer Disease
Screening
Immunoglobulin G
Antibodies
32 Citations (Scopus)

β-Hexachlorocyclohexane levels in serum and risk of Parkinson's disease

Richardson, J. R., Roy, A., Shalat, S. L., Buckley, B., Winnik, B., Gearing, M., Levey, A. I., Factor, S. A., O'Suilleabhain, P. & German, D. C., Oct 2011, In : NeuroToxicology. 32, 5, p. 640-645 6 p.

Research output: Contribution to journalArticle

Lindane
Parkinson Disease
Serum
Pesticides
Odds Ratio
2009
33 Citations (Scopus)

A stereotactic near-infrared probe for localization during functional neurosurgical procedures: Further experience - Clinical article

Giller, C. A., Liu, H., German, D. C., Kashyap, D. & Dewey, R. B., Feb 2009, In : Journal of Neurosurgery. 110, 2, p. 263-273 11 p.

Research output: Contribution to journalArticle

Neurosurgical Procedures
Microelectrodes
Subthalamic Nucleus
Deep Brain Stimulation
Electrodes
77 Citations (Scopus)

Elevated serum pesticide levels and risk of Parkinson disease

Richardson, J. R., Shalat, S. L., Buckley, B., Winnik, B., O'Suilleabhain, P., Diaz-Arrastia, R., Reisch, J. & German, D. C., Jul 2009, In : Archives of Neurology. 66, 7, p. 870-875 6 p.

Research output: Contribution to journalArticle

Pesticides
Parkinson Disease
Serum
Alzheimer Disease
Odds Ratio
2008
13 Citations (Scopus)

Chronic intraventricular administration of 1-methyl-4-phenylpyridinium as a progressive model of Parkinson's disease

Sonsalla, P. K., Zeevalk, G. D. & German, D. C., Jul 2008, In : Parkinsonism and Related Disorders. 14, SUPPL.2

Research output: Contribution to journalArticle

1-Methyl-4-phenylpyridinium
Parkinson Disease
Corpus Striatum
Cerebral Ventricles
Lateral Ventricles
32 Citations (Scopus)

Major depression, 5HTTLPR genotype, suicide and antidepressant influences on thalamic volume

Young, K. A., Bonkale, W. L., Holcomb, L. A., Hicks, P. B. & German, D. C., Apr 2008, In : British Journal of Psychiatry. 192, 4, p. 285-289 5 p.

Research output: Contribution to journalArticle

Thalamus
Suicide
Antidepressive Agents
Major Depressive Disorder
Genotype
2007
48 Citations (Scopus)

5HTTLPR Polymorphism and Enlargement of the Pulvinar: Unlocking the Backdoor to the Limbic System

Young, K. A., Holcomb, L. A., Bonkale, W. L., Hicks, P. B., Yazdani, U. & German, D. C., Mar 15 2007, In : Biological Psychiatry. 61, 6, p. 813-818 6 p.

Research output: Contribution to journalArticle

Pulvinar
Limbic System
Serotonin Plasma Membrane Transport Proteins
Neurons
Genotype
8 Citations (Scopus)

A robust biomarker discovery pipeline for high-performance mass spectrometry data

Fisher, W. G., Rosenblatt, K. P., Fishman, D. A., Whitteley, G. R., Mikulskis, A., Kuzdzal, S. A., Lopez, M. F., Tan, N. C., German, D. C. & Garner, H. R., Oct 2007, In : Journal of Bioinformatics and Computational Biology. 5, 5, p. 1023-1045 23 p.

Research output: Contribution to journalArticle

Biomarkers
Mass spectrometry
Mass Spectrometry
Pipelines
Ovarian Neoplasms
122 Citations (Scopus)

Mitochondria mass is low in mouse substantia nigra dopamine neurons: Implications for Parkinson's disease

Liang, C. L., Wang, T. T., Luby-Phelps, K. & German, D. C., Feb 2007, In : Experimental Neurology. 203, 2, p. 370-380 11 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Substantia Nigra
Parkinson Disease
Mitochondria
Neurons
48 Citations (Scopus)

Serum biomarkers for Alzheimer's disease: Proteomic discovery

German, D. C., Gurnani, P., Nandi, A., Garner, H. R., Fisher, W., Diaz-Arrastia, R., O'Suilleabhain, P. & Rosenblatt, K. P., Aug 2007, In : Biomedicine and Pharmacotherapy. 61, 7, p. 383-389 7 p.

Research output: Contribution to journalArticle

Proteomics
Alzheimer Disease
Biomarkers
Serum
Costs and Cost Analysis
2006
282 Citations (Scopus)

Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease

Donovan, M. H., Yazdani, U., Norris, R. D., Games, D., German, D. C. & Eisch, A. J., Mar 1 2006, In : Journal of Comparative Neurology. 495, 1, p. 70-83 14 p.

Research output: Contribution to journalArticle

Neurogenesis
Alzheimer Disease
Neurons
Parturition
Dentate Gyrus
52 Citations (Scopus)

Rat model of Parkinson's disease: Chronic central delivery of 1-methyl-4-phenylpyridinium (MPP+)

Yazdani, U., German, D. C., Liang, C. L., Manzino, L., Sonsalla, P. K. & Zeevalk, G. D., Jul 2006, In : Experimental Neurology. 200, 1, p. 172-183 12 p.

Research output: Contribution to journalArticle

1-Methyl-4-phenylpyridinium
Substantia Nigra
Parkinson Disease
Dopaminergic Neurons
Tyrosine 3-Monooxygenase
2005
90 Citations (Scopus)

Determination of reduced scattering coefficient of biological tissue from a needle-like probe

Johns, M., Giller, C. A., German, D. C. & Liu, H., Jun 27 2005, In : Optics Express. 13, 13, p. 4828-4842 15 p.

Research output: Contribution to journalArticle

scattering coefficients
needles
probes
reflectance
frequency standards
95 Citations (Scopus)

Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease

Li, H., Repa, J. J., Valasek, M. A., Beltroy, E. P., Turley, S. D., German, D. C. & Dietschy, J. M., Apr 2005, In : Journal of Neuropathology and Experimental Neurology. 64, 4, p. 323-333 11 p.

Research output: Contribution to journalArticle

Type C Niemann-Pick Disease
Apolipoproteins E
Cholesterol
Cerebellum
Caspase 1
2004
283 Citations (Scopus)

Double-knockout mice for α- and β-synucleins: Effect on synaptic functions

Chandra, S., Fornai, F., Kwon, H. B., Yazdani, U., Atasoy, D., Liu, X., Hammer, R. E., Battaglia, G., German, D. C., Castillo, P. E. & Südhof, T. C., Oct 12 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 41, p. 14966-14971 6 p.

Research output: Contribution to journalArticle

Synucleins
Knockout Mice
14-3-3 Proteins
Dopamine
Neuronal Plasticity
108 Citations (Scopus)

Elevated neuron number in the limbic thalamus in major depression

Young, K. A., Holcomb, L. A., Yazdani, U., Hicks, P. B. & German, D. C., Jul 2004, In : American Journal of Psychiatry. 161, 7, p. 1270-1277 8 p.

Research output: Contribution to journalArticle

Thalamus
Major Depressive Disorder
Anterior Thalamic Nuclei
Depression
Neurons
68 Citations (Scopus)

Inverse Relationship between the Contents of Neuromelanin Pigment and the Vesicular Monoamine Transporter-2: Human Midbrain Dopamine Neurons

Liang, C. L., Nelson, O., Yazdani, U., Pasbakhsh, P. & German, D. C., May 17 2004, In : Journal of Comparative Neurology. 473, 1, p. 97-106 10 p.

Research output: Contribution to journalArticle

Vesicular Monoamine Transport Proteins
Dopaminergic Neurons
Mesencephalon
Neurons
Substantia Nigra
107 Citations (Scopus)

Mouse models of Alzheimer's disease: Insight into treatment

German, D. C. & Eisch, A. J., 2004, In : Reviews in the Neurosciences. 15, 5, p. 353-369 17 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Alzheimer Disease
Neurofibrillary Tangles
Neurogenesis
Amyloid Plaques
2003
87 Citations (Scopus)

Cholinergic neuropathology in a mouse model of Alzheimer's disease

German, D. C., Yazdani, U., Speciale, S. G., Pasbakhsh, P., Games, D. & Liang, C. L., Jul 5 2003, In : Journal of Comparative Neurology. 462, 4, p. 371-381 11 p.

Research output: Contribution to journalArticle

Cholinergic Agents
Alzheimer Disease
Amyloid Plaques
Pathology
Amyloid beta-Protein Precursor
36 Citations (Scopus)

Validation of a near-infrared probe for detection of thin intracranial white matter structures

Giller, C. A., Liu, H., Gurnani, P., Victor, S., Yazdani, U. & German, D. C., Jun 1 2003, In : Journal of Neurosurgery. 98, 6, p. 1299-1306 8 p.

Research output: Contribution to journalArticle

Corpus Callosum
Computer Simulation
Rodentia
Supine Position
Gelatin
2002
141 Citations (Scopus)

Neurodegeneration in the Niemann-Pick C mouse: Glial involvement

German, D. C., Liang, C. L., Song, T., Yazdani, U., Xie, C. & Dietschy, J. M., Feb 14 2002, In : Neuroscience. 109, 3, p. 437-450 14 p.

Research output: Contribution to journalArticle

Cathepsin D
Neuroglia
Astrocytes
Corpus Callosum
Myelin Sheath
2001
37 Citations (Scopus)

Degeneration of neurons and glia in the Niemann-Pick C mouse is unrelated to the low-density lipoprotein receptor

German, D. C., Quintero, E. M., Liang, C. L., Xie, C. & Dietschy, J. M., Aug 22 2001, In : Neuroscience. 105, 4, p. 999-1005 7 p.

Research output: Contribution to journalArticle

Nerve Degeneration
LDL Receptors
Neuroglia
Purkinje Cells
Niemann-Pick Diseases
94 Citations (Scopus)

Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease

German, D. C., Matthew Quintero, E., Liang, C. L., Ng, B., Punia, S., Xie, C. & Dietschy, J. M., May 7 2001, In : Journal of Comparative Neurology. 433, 3, p. 415-425 11 p.

Research output: Contribution to journalArticle

Niemann-Pick Diseases
Neurofibrillary Tangles
Neurons
Neuroglia
Corpus Callosum
2000
52 Citations (Scopus)
Vesicular Monoamine Transport Proteins
1-Methyl-4-phenylpyridinium
Corpus Striatum
Dopaminergic Neurons
Dopamine
37 Citations (Scopus)
Vesicular Monoamine Transport Proteins
Adrenergic Neurons
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Locus Coeruleus
Dopaminergic Neurons
222 Citations (Scopus)

Reduced number of mediodorsal and anterior thalamic neurons in schizophrenia

Young, K. A., Manaye, K. F., Liang, C. L., Hicks, P. B. & German, D. C., Jun 2000, In : Biological Psychiatry. 47, 11, p. 944-953 10 p.

Research output: Contribution to journalArticle

Schizophrenia
Neurons
Thalamus
Anterior Thalamic Nuclei
Prefrontal Cortex
38 Citations (Scopus)

Upregulation of estrogen receptors in the forebrain of aromatase knockout (ArKO) mice

Agarwal, V. R., Sinton, C. M., Liang, C. L., Fisher, C., German, D. C. & Simpson, E. R., Apr 25 2000, In : Molecular and Cellular Endocrinology. 162, 1-2, p. 9-16 8 p.

Research output: Contribution to journalArticle

Aromatase
Prosencephalon
Knockout Mice
Estrogen Receptors
Up-Regulation
1999
107 Citations (Scopus)

Evidence for a deficit in cholinergic interneurons in the striatum in schizophrenia

Holt, D. J., Herman, M. M., Hyde, T. M., Kleinman, J. E., Sinton, C. M., German, D. C., Hersh, L. B., Graybiel, A. M. & Saper, C. B., Sep 1999, In : Neuroscience. 94, 1, p. 21-31 11 p.

Research output: Contribution to journalArticle

Interneurons
Cholinergic Agents
Choline O-Acetyltransferase
Schizophrenia
Calbindin 2
22 Citations (Scopus)

Mesopontine cholinergic and non-cholinergic neurons in schizophrenia

German, D. C., Manaye, K. F., Wu, D., Hersh, L. B. & Zweig, R. M., Sep 1999, In : Neuroscience. 94, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

Cholinergic Neurons
Cholinergic Agents
Schizophrenia
Neurons
Pedunculopontine Tegmental Nucleus
62 Citations (Scopus)

Quantification of cholinergic and select non-cholinergic mesopontine neuronal populations in the human brain

Manaye, K. F., Zweig, R., Wu, D., Hersh, L. B., De Lacalle, S., Saper, C. B. & German, D. C., Mar 1999, In : Neuroscience. 89, 3, p. 759-770 12 p.

Research output: Contribution to journalArticle

Cholinergic Neurons
Cholinergic Agents
Neurons
Brain
Population
1998
72 Citations (Scopus)

Calbindin-D(28k) buffers intracellular calcium and promotes resistance to degeneration in PC12 cells

McMahon, A., Wong, B. S., Iacopino, A. M., Ng, M. C., Chi, S. & German, D. C., Feb 1998, In : Molecular Brain Research. 54, 1, p. 56-63 8 p.

Research output: Contribution to journalArticle

Calbindins
PC12 Cells
Buffers
Calcium
1-Methyl-4-phenylpyridinium
56 Citations (Scopus)

The neurotoxin 1-methyl-4-phenylpyridinium is sequestered within neurons that contain the vesicular monoamine transporter

Speciale, S. G., Liang, C. L., Sonsalla, P. K., Edwards, R. H. & German, D. C., 1998, In : Neuroscience. 84, 4, p. 1177-1185 9 p.

Research output: Contribution to journalArticle

Vesicular Monoamine Transport Proteins
1-Methyl-4-phenylpyridinium
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Neurotoxins
Neurons
1997
44 Citations (Scopus)

Calbindin-D(28k) in nerve cell nuclei

German, D. C., Ng, M. C., Liang, C. L., McMahon, A. & Iacopino, A. M., Sep 26 1997, In : Neuroscience. 81, 3, p. 735-743 9 p.

Research output: Contribution to journalArticle

Calbindins
Cell Nucleus
Neurons
Cytoplasm
Calcium