• 17584 Citations
  • 71 h-Index
1960 …2016

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2016

A history of the DNA repair and mutagenesis field. The discovery of base excision repair.

Friedberg, E. C., Jan 1 2016, In : DNA Repair. 37, p. A35-A39

Research output: Contribution to journalArticle

16 Scopus citations

Editorial

Wilson, S. H. & Friedberg, E. C., Jan 1 2016, In : DNA Repair. 37, p. A1

Research output: Contribution to journalArticle

2015

A history of the DNA repair and mutagenesis field. I. The discovery of enzymatic photoreactivation.

Friedberg, E. C., Sep 1 2015, In : DNA Repair. 33, p. 35-42 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Editorial

Wilson, S. H. & Friedberg, E., Nov 1 2015, In : DNA Repair. 35, p. v

Research output: Contribution to journalArticle

1 Scopus citations

FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress

Yang, Y., Liu, Z., Wang, F., Temviriyanukul, P., Ma, X., Tu, Y., Lv, L., Lin, Y. F., Huang, M., Zhang, T., Pei, H., Chen, B. P. C., Jansen, J. G., De Wind, N., Fischhaber, P. L., Friedberg, E. C., Tang, T. S. & Guo, C., Sep 30 2015, In : Nucleic acids research. 43, 17, p. 8325-8339 15 p.

Research output: Contribution to journalArticle

21 Scopus citations
2014

Variants of mouse DNA polymerase κ reveal a mechanism of efficient and accurate translesion synthesis past a benzo[a]pyrene dG adduct

Liu, Y., Yang, Y., Tang, T. S., Zhang, H., Wang, Z., Friedberg, E., Yang, W. & Guo, C., Feb 4 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 5, p. 1789-1794 6 p.

Research output: Contribution to journalArticle

25 Scopus citations
2013

A life of fixing DNA.

Friedberg, E. C., Jun 1 2013, In : Unknown Journal. 12, 6, p. 389-393 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation

Bétous, R., Pillaire, M. J., Pierini, L., Van Der Laan, S., Recolin, B., Ohl-Séguy, E., Guo, C., Niimi, N., Grúz, P., Nohmi, T., Friedberg, E., Cazaux, C., Maiorano, D. & Hoffmann, J. S., Jul 31 2013, In : EMBO Journal. 32, 15, p. 2172-2185 14 p.

Research output: Contribution to journalArticle

41 Scopus citations

Increased dietary cholesterol promotes enhanced mutagenesis in DNA polymerase kappa-deficient mice

Singer, W. D., Osimiri, L. C. & Friedberg, E. C., Oct 1 2013, In : DNA repair. 12, 10, p. 817-823 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation

Lv, L., Wang, F., Ma, X., Yang, Y., Wang, Z., Liu, H., Li, X., Liu, Z., Zhang, T., Huang, M., Friedberg, E. C., Tang, T. S. & Guo, C., Dec 1 2013, In : Nucleic acids research. 41, 22, p. 10312-10322 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Mouse DNA polymerase kappa has a functional role in the repair of DNA strand breaks

Zhang, X., Lv, L., Chen, Q., Yuan, F., Zhang, T., Yang, Y., Zhang, H., Wang, Y., Jia, Y., Qian, L., Chen, B., Zhang, Y., Friedberg, E. C., Tang, T. S. & Guo, C., May 1 2013, In : DNA repair. 12, 5, p. 377-388 12 p.

Research output: Contribution to journalArticle

22 Scopus citations
2012

Foreword

Friedberg, E. C., 2012, In : Unknown Journal.

Research output: Contribution to journalArticle

Targeted detection of in vivo endogenous DNA base damage reveals preferential base excision repair in the transcribed strand

Reis, A. M. C., Mills, W. K., Ramachandran, I., Friedberg, E. C., Thompson, D. & Queimado, L., Jan 1 2012, In : Nucleic acids research. 40, 1, p. 206-219 14 p.

Research output: Contribution to journalArticle

12 Scopus citations
2011

Nucleotide excision repair of DNA: The very early history

Friedberg, E. C., Jul 15 2011, In : DNA repair. 10, 7, p. 668-672 5 p.

Research output: Contribution to journalArticle

11 Scopus citations
2010

A comprehensive catalogue of somatic mutations in cancer genomes

Friedberg, E. C., Apr 4 2010, In : DNA repair. 9, 4, p. 468-469 2 p.

Research output: Contribution to journalArticle

2 Scopus citations
2009

ABF1-binding sites promote efficient global genome nucleotide excision repair

Yu, S., Smirnova, J. B., Friedberg, E. C., Stillman, B., Akiyama, M., Owen-Hughes, T., Waters, R. & Reed, S. H., Jan 9 2009, In : Journal of Biological Chemistry. 284, 2, p. 966-973 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli

Galhardo, R. S., Do, R., Yamada, M., Friedberg, E. C., Hastings, P. J., Nohmi, T. & Rosenberg, S. M., May 1 2009, In : Genetics. 182, 1, p. 55-68 14 p.

Research output: Contribution to journalArticle

85 Scopus citations

Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes

Dragileva, E., Hendricks, A., Teed, A., Gillis, T., Lopez, E. T., Friedberg, E. C., Kucherlapati, R., Edelmann, W., Lunetta, K. L., MacDonald, M. E. & Wheeler, V. C., Jan 1 2009, In : Neurobiology of Disease. 33, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

106 Scopus citations

Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice

Unnikrishnan, A., Raffoul, J. J., Patel, H. V., Prychitko, T. M., Anyangwe, N., Meira, L. B., Friedberg, E. C., Cabelof, D. C. & Heydari, A. R., Jun 1 2009, In : Free Radical Biology and Medicine. 46, 11, p. 1488-1499 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Polk mutant mice have a spontaneous mutator phenotype

Stancel, J. N. K., McDaniel, L. D., Velasco, S., Richardson, J., Guo, C. & Friedberg, E. C., Dec 3 2009, In : DNA repair. 8, 12, p. 1355-1362 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Rad10 exhibits lesion-dependent genetic requirements for recruitment to DNA double-strand breaks in Saccharomyces cerevisiae

Moore, D. M., Karlin, J., González-Barrera, S., Mardiros, A., Lisby, M., Doughty, A., Gilley, J., Rothstein, R., Friedberg, E. C. & Fischhaber, P. L., Nov 16 2009, In : Nucleic acids research. 37, 19, p. 6429-6438 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Static electric fields interfere in the viability of cells exposed to ionising radiation

Arruda-Neto, J. D. T., Friedberg, E. C., Bittencourt-Oliveira, M. C., Cavalcante-Silva, E., Schenberg, A. C. G., Rodrigues, T. E., Garcia, F., Louvison, M., Paula, C. R., Mesa, J., Moron, M. M., Maria, D. A. & Genofre, G. C., Apr 1 2009, In : International Journal of Radiation Biology. 85, 4, p. 314-321 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals

Shachar, S., Ziv, O., Avkin, S., Adar, S., Wittschieben, J., Reißner, T., Chaney, S., Friedberg, E. C., Wang, Z., Carell, T., Geacintov, N. & Livneh, Z., Feb 18 2009, In : EMBO Journal. 28, 4, p. 383-393 11 p.

Research output: Contribution to journalArticle

194 Scopus citations
2008

A brief history of the DNA repair field

Friedberg, E. C., Jan 1 2008, In : Cell Research. 18, 1, p. 3-7 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

Comparative analysis of in vivo interactions between Rev1 protein and other Y-family DNA polymerases in animals and yeasts

Kosarek, J. N., Woodruff, R. V., Rivera-Begeman, A., Guo, C., D'Souza, S., Koonin, E. V., Walker, G. C. & Friedberg, E. C., Mar 1 2008, In : DNA repair. 7, 3, p. 439-451 13 p.

Research output: Contribution to journalArticle

35 Scopus citations

Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes

Melis, J. P. M., Wijnhoven, S. W. P., Beems, R. B., Roodbergen, M., Van Den Berg, J., Moon, H., Friedberg, E., Van Der Horst, G. T. J., Hoeijmakers, J. H. J., Vijg, J. & Van Steeg, H., Mar 1 2008, In : Cancer research. 68, 5, p. 1347-1353 7 p.

Research output: Contribution to journalArticle

52 Scopus citations

Obituary: Arthur Kornberg (1918-2007).

Friedberg, E. C., Feb 1 2008, In : DNA repair. 7, 2, 1 p.

Research output: Contribution to journalArticle

Requirements for the interaction of mouse Polκ with ubiquitin and its biological significance

Guo, C., Tang, T. S., Bienko, M., Dikic, I. & Friedberg, E. C., Feb 22 2008, In : Journal of Biological Chemistry. 283, 8, p. 4658-4664 7 p.

Research output: Contribution to journalArticle

53 Scopus citations
2007

Adventures in the golden age of molecular biology.

Friedberg, E. C., Dec 2007, In : Adler Museum bulletin. 33, 2, p. 33-37 5 p.

Research output: Contribution to journalArticle

A novel XPC pathogenic variant detected in archival material from a patient diagnosed with Xeroderma Pigmentosum: A case report and review of the genetic variants reported in XPC

Rivera-Begeman, A., McDaniel, L. D., Schultz, R. A. & Friedberg, E. C., Jan 4 2007, In : DNA repair. 6, 1, p. 100-114 15 p.

Research output: Contribution to journalArticle

13 Scopus citations

Detoxification of olefinic epoxides and nucleotide excision repair of epoxide-mediated DNA damage: Insights from animal models examining human sensitivity to 1,3-butadiene

Wickliffe, J. K., Herring, S. M., Hallberg, L. M., Galbert, L. A., Masters, O. E., Ammenheuser, M. M., Xie, J., Friedberg, E. C., Lloyd, R. S., Abdel-Rahman, S. Z. & Ward, J. B., Mar 20 2007, In : Chemico-Biological Interactions. 166, 1-3, p. 226-231 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with cockayne syndrome

Van Der Pluijm, I., Garinis, G. A., Brandt, R. M. C., Gorgels, T. G. M. F., Wijnhoven, S. W., Diderich, K. E. M., De Wit, J., Mitchell, J. R., Van Oostrom, C., Beems, R., Niedernhofer, L. J., Velasco, S., Friedberg, E. C., Tanaka, K., Van Steeg, H., Hoeijmakers, J. H. J. & Van Der Horst, G. T. J., Jan 2007, In : PLoS biology. 5, 1, p. 23-38 16 p.

Research output: Contribution to journalArticle

169 Scopus citations

Report of the Working Group on Integrated Translational Research in DNA Repair

Reinlib, L. & Friedberg, E. C., Jan 4 2007, In : DNA repair. 6, 1, p. 145-147 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

The 3rd Japan-US DNA Repair Meeting, Sendai, Japan, May 7-11, 2007

Friedberg, E. C., Hanaoka, F., Tanaka, K., Wilson, S. & Yasui, A., Oct 1 2007, In : DNA repair. 6, 10, p. 1545-1555 11 p.

Research output: Contribution to journalArticle

The combined effects of xeroderma pigmentosum C deficiency and mutagens on mutation rates in the mouse germ line

Miccoli, L., Burr, K. L. A., Hickenbotham, P., Friedberg, E. C., Angulo, J. F. & Dubrova, Y. E., May 15 2007, In : Cancer Research. 67, 10, p. 4695-4699 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

The writing life of James D. Watson: writing and publishing "The Double Helix".

Friedberg, E. C., Dec 2007, In : Adler Museum bulletin. 33, 2, p. 3-16 14 p.

Research output: Contribution to journalArticle

Validation of XP-C pathogenic variations in archival material from a live XP patient

McDaniel, L. D., Rivera-Begeman, A., Doughty, A. T., Schultz, R. A. & Friedberg, E. C., Jan 4 2007, In : DNA repair. 6, 1, p. 115-120 6 p.

Research output: Contribution to journalArticle

2006

3,4-Epoxy-1-butene, a reactive metabolite of 1,3-butadiene, induces somatic mutations in Xpc-null mice

Wickliffe, J. K., Galbert, L. A., Ammenheuser, M. M., Herring, S. M., Xie, J., Masters, O. E., Friedberg, E. C., Lloyd, R. S. & Ward, J. B., Jan 1 2006, In : Environmental and Molecular Mutagenesis. 47, 1, p. 67-70 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7

Friedberg, E. C. & Meira, L. B., Feb 3 2006, In : DNA repair. 5, 2, p. 189-209 21 p.

Research output: Contribution to journalArticle

80 Scopus citations

DNA repair: From molecular mechanism to human disease

Friedberg, E. C., Aguilera, A., Gellert, M., Hanawalt, P. C., Hays, J. B., Lehmann, A. R., Lindahl, T., Lowndes, N., Sarasin, A. & Wood, R. D., Aug 13 2006, In : DNA repair. 5, 8, p. 986-996 11 p.

Research output: Contribution to journalArticle

131 Scopus citations

Elevated mutation rates in the germline of Polκ mutant male mice

Burr, K. L. A., Velasco-Miguel, S., Duvvuri, V. S., McDaniel, L. D., Friedberg, E. C. & Dubrova, Y. E., Jul 13 2006, In : DNA repair. 5, 7, p. 860-862 3 p.

Research output: Contribution to journalArticle

27 Scopus citations

Identification of MMS19 domains with distinct functions in NER and transcription

Hatfield, M. D., Reis, A. M. C., Obeso, D., Cook, J. R., Thompson, D. M., Rao, M., Friedberg, E. C. & Queimado, L., Aug 13 2006, In : DNA repair. 5, 8, p. 914-924 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Involvement of vertebrate Polκ in translesion DNA synthesis across DNA monoalkylation damage

Takenaka, K., Ogi, T., Okada, T., Sonoda, E., Guo, C., Friedberg, E. C. & Takeda, S., Jan 27 2006, In : Journal of Biological Chemistry. 281, 4, p. 2000-2004 5 p.

Research output: Contribution to journalArticle

34 Scopus citations

REV1 Protein Interacts with PCNA: Significance of the REV1 BRCT Domain In Vitro and In Vivo

Guo, C., Sonoda, E., Tang, T. S., Parker, J. L., Bielen, A. B., Takeda, S., Ulrich, H. D. & Friedberg, E. C., Jul 21 2006, In : Molecular cell. 23, 2, p. 265-271 7 p.

Research output: Contribution to journalArticle

144 Scopus citations

TERF2-XPF: Caught in the middle; beginnings from the end

McDaniel, L. D., Schultz, R. A. & Friedberg, E. C., Jul 13 2006, In : DNA repair. 5, 7, p. 868-872 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damage

Guo, C., Tang, T. S., Bienko, M., Parker, J. L., Bielen, A. B., Sonoda, E., Takeda, S., Ulrich, H. D., Dikic, I. & Friedberg, E. C., Dec 1 2006, In : Molecular and cellular biology. 26, 23, p. 8892-8900 9 p.

Research output: Contribution to journalArticle

154 Scopus citations
2005

Defining the biochemistry of mismatch repair

Friedberg, E. C., Jan 2 2005, In : DNA repair. 4, 1, p. 133-139 7 p.

Research output: Contribution to journalArticle

Deletion of XPC leads to lung tumors in mice and is associated with early events in human lung carcinogenesis

Hollander, M. C., Philburn, R. T., Patterson, A. D., Velasco-Miguel, S., Friedberg, E. C., Linnoila, R. I. & Fornace, A. J., Sep 13 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 37, p. 13200-13205 6 p.

Research output: Contribution to journalArticle

97 Scopus citations
19 Scopus citations