• 17491 Citations
  • 71 h-Index
1960 …2016
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Research Output 1960 2016

  • 17491 Citations
  • 71 h-Index
  • 381 Article
  • 9 Chapter
  • 1 Book
  • 1 Foreword/postscript
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Article
2016
13 Citations (Scopus)

A history of the DNA repair and mutagenesis field. The discovery of base excision repair.

Friedberg, E. C., Jan 1 2016, In : DNA Repair. 37, p. A35-A39

Research output: Contribution to journalArticle

Mutagenesis
DNA Repair
Repair
DNA
Nucleotides

Editorial

Wilson, S. H. & Friedberg, E. C., Jan 1 2016, In : DNA Repair. 37, p. A1

Research output: Contribution to journalArticle

Biochemistry
2015
5 Citations (Scopus)

A history of the DNA repair and mutagenesis field. I. The discovery of enzymatic photoreactivation.

Friedberg, E. C., Sep 1 2015, In : DNA Repair. 33, p. 35-42 8 p.

Research output: Contribution to journalArticle

Mutagenesis
DNA Repair
Repair
Pyrimidine Dimers
DNA
1 Citation (Scopus)

Editorial

Wilson, S. H. & Friedberg, E., Nov 1 2015, In : DNA Repair. 35, p. v

Research output: Contribution to journalArticle

Nobel Prize
DNA Repair
21 Citations (Scopus)

FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress

Yang, Y., Liu, Z., Wang, F., Temviriyanukul, P., Ma, X., Tu, Y., Lv, L., Lin, Y. F., Huang, M., Zhang, T., Pei, H., Chen, B. P. C., Jansen, J. G., De Wind, N., Fischhaber, P. L., Friedberg, E. C., Tang, T. S. & Guo, C., Sep 30 2015, In : Nucleic Acids Research. 43, 17, p. 8325-8339 15 p.

Research output: Contribution to journalArticle

Homologous Recombination
DNA Damage
Lasers
Gene Conversion
Camptothecin
2014

Master molecule, heal thyself

Friedberg, E. C., May 16 2014, In : Journal of Biological Chemistry. 289, 20, p. 13691-13700 10 p.

Research output: Contribution to journalArticle

DNA Glycosylases
Molecular biology
Deoxyribonuclease I
Molecules
DNA
24 Citations (Scopus)

Variants of mouse DNA polymerase κ reveal a mechanism of efficient and accurate translesion synthesis past a benzo[a]pyrene dG adduct

Liu, Y., Yang, Y., Tang, T. S., Zhang, H., Wang, Z., Friedberg, E., Yang, W. & Guo, C., Feb 4 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 5, p. 1789-1794 6 p.

Research output: Contribution to journalArticle

Benzo(a)pyrene
Epoxy Compounds
DNA-Directed DNA Polymerase
DNA
Polymerization
2013
1 Citation (Scopus)

A life of fixing DNA.

Friedberg, E. C., Jun 1 2013, In : DNA Repair. 12, 6, p. 389-393 5 p.

Research output: Contribution to journalArticle

21st Century History
20th Century History
South Africa
DNA Repair
DNA
40 Citations (Scopus)

DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation

Bétous, R., Pillaire, M. J., Pierini, L., Van Der Laan, S., Recolin, B., Ohl-Séguy, E., Guo, C., Niimi, N., Grúz, P., Nohmi, T., Friedberg, E., Cazaux, C., Maiorano, D. & Hoffmann, J. S., Jul 31 2013, In : EMBO Journal. 32, 15, p. 2172-2185 14 p.

Research output: Contribution to journalArticle

Genomic Instability
DNA-Directed DNA Polymerase
Chemical activation
Cells
Phosphorylation
9 Citations (Scopus)

Increased dietary cholesterol promotes enhanced mutagenesis in DNA polymerase kappa-deficient mice

Singer, W. D., Osimiri, L. C. & Friedberg, E. C., Oct 2013, In : DNA Repair. 12, 10, p. 817-823 7 p.

Research output: Contribution to journalArticle

Dietary Cholesterol
Mutagenesis
Apolipoproteins E
DNA-Directed DNA Polymerase
Cholesterol
19 Citations (Scopus)

Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation

Lv, L., Wang, F., Ma, X., Yang, Y., Wang, Z., Liu, H., Li, X., Liu, Z., Zhang, T., Huang, M., Friedberg, E. C., Tang, T. S. & Guo, C., Dec 2013, In : Nucleic Acids Research. 41, 22, p. 10312-10322 11 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
DNA-Directed DNA Polymerase
Proliferating Cell Nuclear Antigen
Radiation
DNA
22 Citations (Scopus)

Mouse DNA polymerase kappa has a functional role in the repair of DNA strand breaks

Zhang, X., Lv, L., Chen, Q., Yuan, F., Zhang, T., Yang, Y., Zhang, H., Wang, Y., Jia, Y., Qian, L., Chen, B., Zhang, Y., Friedberg, E. C., Tang, T. S. & Guo, C., May 1 2013, In : DNA Repair. 12, 5, p. 377-388 12 p.

Research output: Contribution to journalArticle

DNA Breaks
DNA-Directed DNA Polymerase
Repair
DNA
Nuclear Localization Signals

The molecular basis of mutagenesis - 40 years of research on genomic integrity

Friedberg, E. C., 2013, In : South African Medical Journal. 103, SUPPL. 1, p. 982-983 2 p.

Research output: Contribution to journalArticle

Eukaryota
Mutagenesis
DNA Damage
Research
2012

Foreword

Friedberg, E. C., 2012, In : Unknown Journal.

Research output: Contribution to journalArticle

Happy 10th birthday

Friedberg, E. C., Jan 2 2012, In : DNA Repair. 11, 1, p. 2 1 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Targeted detection of in vivo endogenous DNA base damage reveals preferential base excision repair in the transcribed strand

Reis, A. M. C., Mills, W. K., Ramachandran, I., Friedberg, E. C., Thompson, D. & Queimado, L., Jan 2012, In : Nucleic Acids Research. 40, 1, p. 206-219 14 p.

Research output: Contribution to journalArticle

DNA Repair
DNA Damage
Nucleotides
Yeasts
Dermatoglyphics
2011

Autobiographical series

Friedberg, E. C., Aug 15 2011, In : DNA Repair. 10, 8, p. 800 1 p.

Research output: Contribution to journalArticle

Mutagenesis
Genetics
10 Citations (Scopus)

Nucleotide excision repair of DNA: The very early history

Friedberg, E. C., Jul 15 2011, In : DNA Repair. 10, 7, p. 668-672 5 p.

Research output: Contribution to journalArticle

DNA Repair
Repair
Nucleotides
History
Blueprints

Supplementary information in published manuscripts

Friedberg, E. C., Jan 2 2011, In : DNA Repair. 10, 1, p. 2 1 p.

Research output: Contribution to journalArticle

Information dissemination
Information retrieval
2010
2 Citations (Scopus)

A closer look at bibliometrics

Friedberg, E. C., Oct 5 2010, In : DNA Repair. 9, 10, p. 1018-1020 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A comprehensive catalogue of somatic mutations in cancer genomes

Friedberg, E. C., Apr 4 2010, In : DNA Repair. 9, 4, p. 468-469 2 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
DNA Sequence Analysis
DNA Repair
Melanoma
Genes
2 Citations (Scopus)

Good news on the horizon: The Open Researcher and Contributor ID (ORCID)

Friedberg, E. C., Feb 4 2010, In : DNA Repair. 9, 2, p. 102 1 p.

Research output: Contribution to journalArticle

International cooperation
4 Citations (Scopus)

Peer review of scientific papers-A never-ending conundrum

Friedberg, E. C., May 4 2010, In : DNA Repair. 9, 5, p. 476-477 2 p.

Research output: Contribution to journalArticle

Medicine
10 Citations (Scopus)

SnapShot: Nucleotide Excision Repair

Guo, C., Tang, T. S. & Friedberg, E. C., Mar 5 2010, In : Cell. 140, 5

Research output: Contribution to journalArticle

Repair
Nucleotides
1 Citation (Scopus)

The role played by endogenous and exogenous electric fields in DNA signaling and repair

Arruda-Neto, J. D. T., Friedberg, E. C., Bittencourt-Oliveira, M. C., Segreto, H. R. C., Moron, M. M., Maria, D. A., Batista, L. F. Z. & Schenberg, A. C. G., Apr 4 2010, In : DNA Repair. 9, 4, p. 356-357 2 p.

Research output: Contribution to journalArticle

Radiation-Sensitizing Agents
DNA Repair
Repair
Electric fields
DNA
2009
16 Citations (Scopus)

ABF1-binding sites promote efficient global genome nucleotide excision repair

Yu, S., Smirnova, J. B., Friedberg, E. C., Stillman, B., Akiyama, M., Owen-Hughes, T., Waters, R. & Reed, S. H., Jan 9 2009, In : Journal of Biological Chemistry. 284, 2, p. 966-973 8 p.

Research output: Contribution to journalArticle

DNA Repair
Repair
Nucleotides
Genes
Binding Sites
84 Citations (Scopus)

DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli

Galhardo, R. S., Do, R., Yamada, M., Friedberg, E. C., Hastings, P. J., Nohmi, T. & Rosenberg, S. M., May 2009, In : Genetics. 182, 1, p. 55-68 14 p.

Research output: Contribution to journalArticle

Mutagenesis
Up-Regulation
Escherichia coli
Alleles
Lac Operon
1 Citation (Scopus)

Erratum: Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals (The EMBO Journal (2009) 28 (992) DOI: 10.1038/emboj.2009.72)

Shachar, S., Ziv, O., Avkin, S., Adar, S., Wittschieben, J., Reiner, T., Chaney, S., Friedberg, E. C., Wang, Z., Carell, T., Geacintov, N. & Livneh, Z., Apr 8 2009, In : EMBO Journal. 28, 7, p. 992 1 p.

Research output: Contribution to journalArticle

Mammals
DNA
104 Citations (Scopus)

Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes

Dragileva, E., Hendricks, A., Teed, A., Gillis, T., Lopez, E. T., Friedberg, E. C., Kucherlapati, R., Edelmann, W., Lunetta, K. L., MacDonald, M. E. & Wheeler, V. C., Jan 2009, In : Neurobiology of Disease. 33, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

Corpus Striatum
Huntington Disease
DNA Repair
Genes
DNA Mismatch Repair
37 Citations (Scopus)

Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice

Unnikrishnan, A., Raffoul, J. J., Patel, H. V., Prychitko, T. M., Anyangwe, N., Meira, L. B., Friedberg, E. C., Cabelof, D. C. & Heydari, A. R., Jun 1 2009, In : Free Radical Biology and Medicine. 46, 11, p. 1488-1499 12 p.

Research output: Contribution to journalArticle

DNA-(Apurinic or Apyrimidinic Site) Lyase
Oxidative stress
Endonucleases
DNA Repair
Oxidation-Reduction
38 Citations (Scopus)

Polk mutant mice have a spontaneous mutator phenotype

Stancel, J. N. K., McDaniel, L. D., Velasco, S., Richardson, J., Guo, C. & Friedberg, E. C., Dec 3 2009, In : DNA Repair. 8, 12, p. 1355-1362 8 p.

Research output: Contribution to journalArticle

Liver
Genes
Phenotype
Mutagenesis
Bacteriophages
7 Citations (Scopus)

Rad10 exhibits lesion-dependent genetic requirements for recruitment to DNA double-strand breaks in Saccharomyces cerevisiae

Moore, D. M., Karlin, J., González-Barrera, S., Mardiros, A., Lisby, M., Doughty, A., Gilley, J., Rothstein, R., Friedberg, E. C. & Fischhaber, P. L., 2009, In : Nucleic Acids Research. 37, 19, p. 6429-6438 10 p.

Research output: Contribution to journalArticle

Double-Stranded DNA Breaks
Saccharomyces cerevisiae
Yeasts
Endonucleases
Homologous Recombination
4 Citations (Scopus)

Static electric fields interfere in the viability of cells exposed to ionising radiation

Arruda-Neto, J. D. T., Friedberg, E. C., Bittencourt-Oliveira, M. C., Cavalcante-Silva, E., Schenberg, A. C. G., Rodrigues, T. E., Garcia, F., Louvison, M., Paula, C. R., Mesa, J., Moron, M. M., Maria, D. A. & Genofre, G. C., Apr 2009, In : International Journal of Radiation Biology. 85, 4, p. 314-321 8 p.

Research output: Contribution to journalArticle

Ionizing Radiation
Cell Survival
Candida albicans
DNA Repair
Microcystis
193 Citations (Scopus)

Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals

Shachar, S., Ziv, O., Avkin, S., Adar, S., Wittschieben, J., Reißner, T., Chaney, S., Friedberg, E. C., Wang, Z., Carell, T., Geacintov, N. & Livneh, Z., Feb 18 2009, In : EMBO Journal. 28, 4, p. 383-393 11 p.

Research output: Contribution to journalArticle

Mammals
DNA
DNA-Directed DNA Polymerase
Genetic Epistasis
Cyclobutanes
106 Citations (Scopus)

Y-family DNA polymerases in mammalian cells

Guo, C., Kosarek-Stancel, J. N., Tang, T. S. & Friedberg, E. C., Jul 2009, In : Cellular and Molecular Life Sciences. 66, 14, p. 2363-2381 19 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
DNA
Nucleotides
Exonucleases
Proliferating Cell Nuclear Antigen
2008

Aaron Klug

Friedberg, E. C., Feb 2008, In : Nature Reviews Molecular Cell Biology. 9, 2, p. 96-97 2 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

A brief history of the DNA repair field

Friedberg, E. C., Jan 2008, In : Cell Research. 18, 1, p. 3-7 5 p.

Research output: Contribution to journalArticle

DNA Repair
History
DNA Damage

An interview with... Alex Rich

Friedberg, E. C., Apr 2008, In : Nature Reviews Molecular Cell Biology. 9, 4, p. 270-271 2 p.

Research output: Contribution to journalArticle

Interviews

An interview with... David Baltimore

Friedberg, E. C. & Baltimore, D., Sep 2008, In : Nature Reviews Molecular Cell Biology. 9, 9, p. 670-671 2 p.

Research output: Contribution to journalArticle

21st Century History
20th Century History
Autobiography
Baltimore
Molecular Biology

An interview with... Harold Varmus

Friedberg, E. C., Jul 2008, In : Nature Reviews Molecular Cell Biology. 9, 7, p. 502-503 2 p.

Research output: Contribution to journalArticle

Interviews

An interview with... Philip Leder

Friedberg, E. C., Nov 2008, In : Nature Reviews Molecular Cell Biology. 9, 11, p. 830-831 2 p.

Research output: Contribution to journalArticle

20th Century History
Graduate Education
Systems Biology
Molecular Biology
Interviews
14 Citations (Scopus)

An interview with... Sydney Brenner

Friedberg, E. C., Jan 2008, In : Nature Reviews Molecular Cell Biology. 9, 1, p. 8-9 2 p.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Medical Education
Biomedical Research
Molecular Biology
Animal Models
Boring
4-iodo-2,5-dimethoxyphenylisopropylamine
34 Citations (Scopus)

Comparative analysis of in vivo interactions between Rev1 protein and other Y-family DNA polymerases in animals and yeasts

Kosarek, J. N., Woodruff, R. V., Rivera-Begeman, A., Guo, C., D'Souza, S., Koonin, E. V., Walker, G. C. & Friedberg, E. C., Mar 1 2008, In : DNA Repair. 7, 3, p. 439-451 13 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Yeast
Animals
Yeasts
Diptera
2 Citations (Scopus)

Correction: Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with Cockayne syndrome (Plos Biology (2008) 5, 1, (e2) DOI: 10.1371/journal.pbio.0050002)

Van Der Pluijm, I., Garinis, G. A., Brandt, R. M. C., Gorgels, T. G. M. F., Wijnhoven, S. W., Diderich, K. E. M., De Wit, J., Mitchell, J. R., Van Oostrom, C., Beems, R., Niedernhofer, L. J., Velasco, S., Friedberg, E. C., Tanaka, K., Van Steeg, H., Hoeijmakers, J. H. J. & Van Der Horst, G. T. J., Nov 2008, In : PLoS Biology. 6, 11, p. 2614 1 p., e304.

Research output: Contribution to journalArticle

Cockayne Syndrome
somatomedins
Somatomedins
somatotropin
Growth Hormone
1 Citation (Scopus)

Joan Steitz

Friedberg, E. C., Jun 10 2008, In : Nature Reviews Molecular Cell Biology. 9, 6, p. 428-429 2 p.

Research output: Contribution to journalArticle

Marshall Nirenberg

Friedberg, E. C., Mar 2008, In : Nature Reviews Molecular Cell Biology. 9, 3, p. 190-191 2 p.

Research output: Contribution to journalArticle

carbosulfan

Matthew Meselson

Friedberg, E. C., Dec 2008, In : Nature Reviews Molecular Cell Biology. 9, 12, p. 926-927 2 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes

Melis, J. P. M., Wijnhoven, S. W. P., Beems, R. B., Roodbergen, M., Van Den Berg, J., Moon, H., Friedberg, E., Van Der Horst, G. T. J., Hoeijmakers, J. H. J., Vijg, J. & Van Steeg, H., Mar 1 2008, In : Cancer Research. 68, 5, p. 1347-1353 7 p.

Research output: Contribution to journalArticle

Xeroderma Pigmentosum
Phenotype
Neoplasms
DNA Damage
Lung

Nina Fedoroff

Friedberg, E. C., Oct 2008, In : Nature Reviews Molecular Cell Biology. 9, 10, p. 744-745 2 p.

Research output: Contribution to journalArticle