• 935 Citations
  • 11 h-Index

Research output per year

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Research Output

  • 935 Citations
  • 11 h-Index
  • 13 Article
  • 2 Book
  • 1 Review article

The PI3K–AKT network at the interface of oncogenic signalling and cancer metabolism

Hoxhaj, G. & Manning, B. D., Feb 1 2020, In : Nature Reviews Cancer. 20, 2, p. 74-88 15 p.

Research output: Contribution to journalReview article

  • 24 Scopus citations

    Direct stimulation of NADP + synthesis through Akt-mediated phosphorylation of NAD kinase

    Hoxhaj, G., Ben-Sahra, I., Lockwood, S. E., Timson, R. C., Byles, V., Henning, G. T., Gao, P., Selfors, L. M., Asara, J. M. & Manning, B. D., Jan 1 2019, In : Science. 363, 6431, p. 1088-1092 5 p.

    Research output: Contribution to journalArticle

  • 10 Scopus citations

    Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex

    Howell, J. J., Hellberg, K., Turner, M., Talbott, G., Kolar, M. J., Ross, D. S., Hoxhaj, G., Saghatelian, A., Shaw, R. J. & Manning, B. D., Feb 7 2017, In : Cell Metabolism. 25, 2, p. 463-471 9 p.

    Research output: Contribution to journalArticle

    Open Access
  • 93 Scopus citations

    Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans

    Heintz, C., Doktor, T. K., Lanjuin, A., Escoubas, C. C., Zhang, Y., Weir, H. J., Dutta, S., Silva-García, C. G., Bruun, G. H., Morantte, I., Hoxhaj, G., Manning, B. D., Andresen, B. S. & Mair, W. B., Jan 5 2017, In : Nature. 541, 7635, p. 102-106 5 p.

    Research output: Contribution to journalArticle

  • 66 Scopus citations

    The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels

    Hoxhaj, G., Hughes-Hallett, J., Timson, R. C., Ilagan, E., Yuan, M., Asara, J. M., Ben-Sahra, I. & Manning, B. D., Oct 31 2017, In : Cell Reports. 21, 5, p. 1331-1346 16 p.

    Research output: Contribution to journalArticle

    Open Access
  • 33 Scopus citations