Guiyang Hao

  • 1131 Citations
  • 16 h-Index
20022019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2002 2019

  • 1131 Citations
  • 16 h-Index
  • 37 Article
  • 4 Conference contribution
2019
4 Citations (Scopus)
Open Access
Renal Cell Carcinoma
Ligands
Positron-Emission Tomography
Neoplasms
nivolumab

PET imaging of occult tumours by temporal integration of tumour-acidosis signals from pH-sensitive 64Cu-labelled polymers

Huang, G., Zhao, T., Wang, C., Nham, K., Xiong, Y., Gao, X., Wang, Y., Hao, G., Ge, W., Sun, X., Sumer, B. D. & Gao, J., Jan 1 2019, In : Nature Biomedical Engineering.

Research output: Contribution to journalArticle

Acidosis
Tumors
Polymers
Imaging techniques
Neoplasms
1 Citation (Scopus)

Tumor uptake of triazine dendrimers decorated with four, sixteen, and sixty-four PSMA-targeted ligands: Passive versus active tumor targeting

Lim, J., Guan, B., Nham, K., Hao, G., Sun, X. & Simanek, E. E., Sep 1 2019, In : Biomolecules. 9, 9, 421.

Research output: Contribution to journalArticle

Open Access
Dendrimers
Triazines
Tumors
Ligands
Acids
2018
27 Citations (Scopus)

An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents

Zhang, F., Hao, G., Shao, M., Nham, K., An, Y., Wang, Q., Zhu, Y., Kusminski, C., Hassan, G., Gupta, R. K., Zhai, Q., Sun, X., Scherer, P. E. & Oz, O. K., Jan 9 2018, In : Cell Metabolism. 27, 1, p. 252-262.e3

Research output: Contribution to journalArticle

Forensic Anthropology
Atlases
Adipose Tissue
Rodentia
Fluorodeoxyglucose F18
86 Citations (Scopus)

PD-L1 on host cells is essential for PD-L1 blockade–mediated tumor regression

Tang, H., Liang, Y., Anders, R. A., Taube, J. M., Qiu, X., Mulgaonkar, A., Liu, X., Harrington, S. M., Guo, J., Xin, Y., Xiong, Y., Nham, K., Silvers, W., Hao, G., Sun, X., Chen, M., Hannan, R., Qiao, J., Dong, H., Peng, H. & 1 others, Fu, Y. X., Feb 1 2018, In : Journal of Clinical Investigation. 128, 2, p. 580-588 9 p.

Research output: Contribution to journalArticle

Neoplasms
Antigen-Presenting Cells
T-Lymphocytes
Therapeutics
Myeloid Cells
2016
14 Citations (Scopus)

Design of a Small-Molecule Drug Conjugate for Prostate Cancer Targeted Theranostics

Kumar, A., Mastren, T., Wang, B., Hsieh, J. T., Hao, G. & Sun, X., Jul 20 2016, In : Bioconjugate Chemistry. 27, 7, p. 1681-1689 9 p.

Research output: Contribution to journalArticle

Antigens
Prostatic Neoplasms
Membranes
Urea
Molecules

Spatial and temporal processing for functional imaging probes

Jin, M., Zhao, C., Yu, J., Chen, W., Hao, G., Sun, X. & Balch, G., Mar 10 2016, 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014. Institute of Electrical and Electronics Engineers Inc., 7430819

Research output: Chapter in Book/Report/Conference proceedingConference contribution

probes
norms
smoothing
tumors
surgeons

Spatial denoising methods for low count functional images

Jin, M., Yu, J., Chen, W., Hao, G., Sun, X. & Balch, G., Oct 3 2016, 2015 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2015. Institute of Electrical and Electronics Engineers Inc., 7582233

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Surgery
Tumors
surgery
tumors
Iterative methods
189 Citations (Scopus)

Targeting renal cell carcinoma with a HIF-2 antagonist

Chen, W., Hill, H., Christie, A., Kim, M. S., Holloman, E., Pavia-Jimenez, A., Homayoun, F., Ma, Y., Patel, N., Yell, P., Hao, G., Yousuf, Q., Joyce, A., Pedrosa, I., Geiger, H., Zhang, H., Chang, J., Gardner, K. H., Bruick, R. K., Reeves, C. & 14 others, Hwang, T. H., Courtney, K., Frenkel, E., Sun, X., Zojwalla, N., Wong, T., Rizzi, J. P., Wallace, E. M., Josey, J. A., Xie, Y., Xie, X. J., Kapur, P., McKay, R. M. & Brugarolas, J., 2016, In : Nature. 539, 7627, p. 112-117 6 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Neoplasms
Carcinogenesis
Genetic Suppression
Mutation
2015
3 Citations (Scopus)

[68Ga]-HP-DO3A-nitroimidazole: A promising agent for PET detection of tumor hypoxia

Wu, Y., Hao, G., Ramezani, S., Saha, D., Zhao, D., Sun, X. & Sherry, A. D., Nov 1 2015, In : Contrast Media and Molecular Imaging. 10, 6, p. 465-472 8 p.

Research output: Contribution to journalArticle

Nitroimidazoles
Positron-Emission Tomography
Neoplasms
Injections
SCID Mice
2 Citations (Scopus)

A comparative study of trans- and cis-isomers of a bone-seeking agent, DO2A2P

Hao, G., Liu, W., Hassan, G., Öz, O. K., Kovacs, Z. & Sun, X., Feb 1 2015, In : Bioorganic and Medicinal Chemistry Letters. 25, 3, p. 571-574 4 p.

Research output: Contribution to journalArticle

Isomers
Bone
Bone and Bones
Organophosphonates
Bone Diseases
15 Citations (Scopus)

Click-chemistry strategy for labeling antibodies with copper-64 via a cross-bridged tetraazamacrocyclic chelator scaffold

Kumar, A., Hao, G., Liu, L., Ramezani, S., Hsieh, J. T., Öz, O. K. & Sun, X., Apr 15 2015, In : Bioconjugate Chemistry. 26, 4, p. 782-789 8 p.

Research output: Contribution to journalArticle

Click Chemistry
Chelating Agents
Antibodies
Scaffolds
Labeling
11 Citations (Scopus)

Molecular Platform for Design and Synthesis of Targeted Dual-Modality Imaging Probes

Kumar, A., Zhang, S., Hao, G., Hassan, G., Ramezani, S., Sagiyama, K., Lo, S. T., Takahashi, M., Sherry, A. D., Öz, O. K., Kovacs, Z. & Sun, X., Mar 18 2015, In : Bioconjugate Chemistry. 26, 3, p. 549-558 10 p.

Research output: Contribution to journalArticle

Single-Photon Emission-Computed Tomography
Magnetic resonance imaging
Imaging techniques
Acids
Gadolinium
40 Citations (Scopus)

Renal Clearance and Degradation of Glutathione-Coated Copper Nanoparticles

Yang, S., Sun, S., Zhou, C., Hao, G., Liu, J., Ramezani, S., Yu, M., Sun, X. & Zheng, J., Mar 18 2015, In : Bioconjugate Chemistry. 26, 3, p. 511-519 9 p.

Research output: Contribution to journalArticle

Glutathione Disulfide
Nanoparticles
Glutathione
Copper
Kidney
2014
17 Citations (Scopus)

Dimerization of a phage-display selected peptide for imaging of αvβ6- integrin: Two approaches to the multivalent effect

Singh, A. N., McGuire, M. J., Li, S., Hao, G., Kumar, A., Sun, X. & Brown, K. C., 2014, In : Theranostics. 4, 7, p. 745-760 16 p.

Research output: Contribution to journalArticle

Dimerization
Integrins
Bacteriophages
Peptides
Chelating Agents
7 Citations (Scopus)

Enantiopure bifunctional chelators for copper radiopharmaceuticals - Does chirality matter in radiotracer design?

Singh, A. N., Dakanali, M., Hao, G., Ramezani, S., Kumar, A. & Sun, X., Jun 10 2014, In : European Journal of Medicinal Chemistry. 80, p. 308-315 8 p.

Research output: Contribution to journalArticle

Radiopharmaceuticals
Chirality
Chelating Agents
Copper
Stereoisomerism
14 Citations (Scopus)

Use of Fc-engineered antibodies as clearing agents to increase contrast during PET

Swiercz, R., Chiguru, S., Tahmasbi, A., Ramezani, S. M., Hao, G., Challa, D. K., Lewis, M. A., Kulkarni, P. V., Sun, X., Ober, R. J., Mason, R. P. & Ward, E. S., Jul 1 2014, In : Journal of Nuclear Medicine. 55, 7, p. 1204-1207 4 p.

Research output: Contribution to journalArticle

Antibodies
Molecular Imaging
Injections
Neoplasms
Immunoglobulin G
2013
2 Citations (Scopus)

Acceleration of the acquisition of imaging probes using spatiotemporal processing

Jin, M., Zhao, C., Yu, J., Chen, W., Hao, G. & Sun, X., 2013, IEEE Nuclear Science Symposium Conference Record. Institute of Electrical and Electronics Engineers Inc., 6829274

Research output: Chapter in Book/Report/Conference proceedingConference contribution

acquisition
probes
tumors
Neoplasms
therapy
6 Citations (Scopus)
Anions
Neoplasms
Phosphates
human glutamate carboxypeptidase II
Cell Line
14 Citations (Scopus)

Highly specific PET imaging of prostate tumors in mice with an iodine-124-labeled antibody fragment that targets phosphatidylserine

Stafford, J. H., Hao, G., Best, A. M., Sun, X. & Thorpe, P. E., Dec 19 2013, In : PLoS One. 8, 12, e84864.

Research output: Contribution to journalArticle

positron-emission tomography
Immunoglobulin Fragments
phosphatidylserines
Phosphatidylserines
prostatic neoplasms
12 Citations (Scopus)

In vivo evaluation of medical device-associated inflammation using a macrophage-specific positron emission tomography (PET) imaging probe

Zhou, J., Hao, G., Weng, H., Tsai, Y. T., Baker, D. W., Sun, X. & Tang, L., Apr 1 2013, In : Bioorganic and Medicinal Chemistry Letters. 23, 7, p. 2044-2047 4 p.

Research output: Contribution to journalArticle

Positron emission tomography
Macrophages
Positron-Emission Tomography
Inflammation
Foreign-Body Reaction
6 Citations (Scopus)

Serial Non-Invasive Assessment of Antibody Induced Nephritis in Mice Using Positron Emission Tomography

Hao, G., Du, Y., Zhou, X. J., Guo, J., Sun, X., Mohan, C. & Öz, O. K., Feb 27 2013, In : PLoS One. 8, 2, e57418.

Research output: Contribution to journalArticle

positron-emission tomography
nephritis
Positron emission tomography
Nephritis
Positron-Emission Tomography
74 Citations (Scopus)

The Role of Cdk5 in Neuroendocrine Thyroid Cancer

Pozo, K., Castro-Rivera, E., Tan, C., Plattner, F., Schwach, G., Siegl, V., Meyer, D., Guo, A., Gundara, J., Mettlach, G., Richer, E., Guevara, J. A., Ning, L., Gupta, A., Hao, G., Tsai, L. H., Sun, X., Antich, P., Sidhu, S., Robinson, B. G. & 5 others, Chen, H., Nwariaku, F. E., Pfragner, R., Richardson, J. A. & Bibb, J. A., Oct 14 2013, In : Cancer Cell. 24, 4, p. 499-511 13 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Medullary Thyroid cancer
Retinoblastoma Protein
Calcitonin
Hyperplasia
2012
16 Citations (Scopus)

Analysis of oligo-arginine cell-permeable peptides uptake by prostate cells

Zhou, J., Liu, W., Pong, R. C., Hao, G., Sun, X. & Hsieh, J. T., Apr 2012, In : Amino Acids. 42, 4, p. 1253-1260 8 p.

Research output: Contribution to journalArticle

Arginine
Prostate
Laminin Receptors
Peptides
Glycosaminoglycans
8 Citations (Scopus)

Cyclization of RGD peptide sequences via the macrocyclic chelator DOTA for integrin imaging

Hao, G., Sun, X., Do, Q. N., Ocampo-García, B., Vilchis-Juárez, A., Ferro-Flores, G. & De León-Rodríguez, L. M., Dec 14 2012, In : Dalton Transactions. 41, 46, p. 14051-14054 4 p.

Research output: Contribution to journalArticle

Cyclization
Chelating Agents
Integrins
Tumors
Bearings (structural)
104 Citations (Scopus)

Near-infrared emitting radioactive gold nanoparticles with molecular pharmacokinetics

Zhou, C., Hao, G., Thomas, P., Liu, J., Yu, M., Sun, S., Öz, O. K., Sun, X. & Zheng, J., Oct 1 2012, In : Angewandte Chemie - International Edition. 51, 40, p. 10118-10122 5 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Gold
Single photon emission computed tomography
Nanoprobes
Nanoparticles
19 Citations (Scopus)

Synthesis and PET imaging studies of [18F]2-fluoroquinolin-8-ol ([18F]CABS13) in transgenic mouse models of Alzheimer's disease

Vasdev, N., Cao, P., Van Oosten, E. M., Wilson, A. A., Houle, S., Hao, G., Sun, X., Slavine, N., Alhasan, M., Antich, P. P., Bonte, F. J. & Kulkarni, P., Oct 2012, In : MedChemComm. 3, 10, p. 1228-1230 3 p.

Research output: Contribution to journalArticle

Hydrogenation
Fluorine
Fluorides
Transgenic Mice
Alzheimer Disease
2011
13 Citations (Scopus)

A cell permeable peptide analog as a potential-specific PET imaging probe for prostate cancer detection

Hao, G., Zhou, J., Guo, Y., Long, M. A., Anthony, T., Stanfield, J., Hsieh, J. T. & Sun, X., Nov 2011, In : Amino Acids. 41, 5, p. 1093-1101 9 p.

Research output: Contribution to journalArticle

Positron emission tomography
Positron-Emission Tomography
Fluorescein
Prostatic Neoplasms
Imaging techniques
1 Citation (Scopus)

A new F-18 labeled PET agent for imaging Alzheimer's plaques

Kulkarni, P. V., Vasdev, N., Hao, G., Arora, V., Long, M., Slavine, N., Chiguru, S., Qu, B. X., Sun, X., Bennett, M., Antich, P. P. & Bonte, F. J., 2011, AIP Conference Proceedings. Vol. 1336. p. 383-385 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

brain
fallout
quinoline
mice
animals
39 Citations (Scopus)

Multivalent bifunctional chelator scaffolds for gallium-68 based positron emission tomography imaging probe design: Signal amplification via multivalency

Singh, A. N., Liu, W., Hao, G., Kumar, A., Gupta, A., Öz, O. K., Hsieh, J. T. & Sun, X., Aug 17 2011, In : Bioconjugate Chemistry. 22, 8, p. 1650-1662 13 p.

Research output: Contribution to journalArticle

Gallium
Positron emission tomography
Chelating Agents
Scaffolds
Integrins
20 Citations (Scopus)

Recent advances in copper radiopharmaceuticals

Hao, G., Singh, A. N., Öz, O. K. & Sun, X., Apr 2011, In : Current Radiopharmaceuticals. 4, 2, p. 109-121 13 p.

Research output: Contribution to journalArticle

Radiopharmaceuticals
Copper
Radioisotopes
Positron-Emission Tomography
Electrons
2010
36 Citations (Scopus)

Folic acid-CdTe quantum dot conjugates and their applications for cancer cell targeting

Suriamoorthy, P., Zhang, X., Hao, G., Joly, A. G., Singh, S., Hossu, M., Sun, X. & Chen, W., Dec 2010, In : Cancer Nanotechnology. 1, 1-6, p. 19-28 10 p.

Research output: Contribution to journalArticle

folic acid
Quantum Dots
Folic Acid
Semiconductor quantum dots
cancer
42 Citations (Scopus)

Multimodality imaging of hypoxia in preclinical settings

Mason, R. P., Zhao, D., Pacheco-Torres, J., Cui, W., Kodibagkar, V. D., Gulaka, P. K., Hao, G., Thorpe, P., Hahn, E. W. & Peschke, P., Jun 2010, In : Quarterly Journal of Nuclear Medicine and Molecular Imaging. 54, 3, p. 259-280 22 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Radiobiology
Neoplasms
Oximetry
Growth and Development
12 Citations (Scopus)

PET with non-standard nuclides

Hao, G., Singh, A. N., Liu, W. & Sun, X., 2010, In : Current Topics in Medicinal Chemistry. 10, 11, p. 1096-1112 17 p.

Research output: Contribution to journalArticle

Positron-Emission Tomography
Gamma Rays
Single-Photon Emission-Computed Tomography
Radionuclide Imaging
Electrons
166 Citations (Scopus)

Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis

Xie, D., Gore, C., Liu, J., Pong, R. C., Mason, R., Hao, G., Long, M., Kabbani, W., Yu, L., Zhang, H., Chen, H., Sun, X., Boothman, D. A., Min, W. & Hsieh, J. T., Feb 9 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 6, p. 2485-2490 6 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Prostatic Neoplasms
Neoplasm Metastasis
Prostate
TCF Transcription Factors
2009
8 Citations (Scopus)

Cation exchange separation of 61Cu2+ from natCo targets and preparation of 61Cu-DOTA-HSA as a blood pool agent

Hao, G., Fukumura, T., Nakao, R., Suzuki, H., Szelecsényi, F., Kovács, Z. & Suzuki, K., Apr 2009, In : Applied Radiation and Isotopes. 67, 4, p. 511-515 5 p.

Research output: Contribution to journalArticle

albumins
serums
blood
cations
preparation
57 Citations (Scopus)

Imparting multivalency to a bifunctional chelator: A scaffold design for targeted PET imaging probes

Liu, W., Hao, G., Long, M. A., Anthony, T., Hsieh, J. T. & Sun, X., Sep 21 2009, In : Angewandte Chemie - International Edition. 48, 40, p. 7346-7349 4 p.

Research output: Contribution to journalArticle

Chelating Agents
Scaffolds
Ligands
Imaging techniques
Functional groups
2008
19 Citations (Scopus)

Preparation and biological evaluation of 99mTc-CO-MIBI as myocardial perfusion imaging agent

Chen, X., Guo, Y., Zhang, Q., Hao, G., Jia, H. & Liu, B., May 1 2008, In : Journal of Organometallic Chemistry. 693, 10, p. 1822-1828 7 p.

Research output: Contribution to journalArticle

myocardium
Myocardial Perfusion Imaging
rhenium
Carbon Monoxide
liver
2007
6 Citations (Scopus)

Preparation and biodistribution of novel 99mTc(CO) 3-CNR complexes for myocardial imaging

Hao, G., Zang, J. & Liu, B., Jan 2007, In : Journal of Labelled Compounds and Radiopharmaceuticals. 50, 1, p. 13-18 6 p.

Research output: Contribution to journalArticle

Carbon Monoxide
Imaging techniques
Radiopharmaceuticals
Radio
Liver
2004
20 Citations (Scopus)

Synthesis, separation and biodistribution of 99mTc-CO-MIBI complex

Hao, G. Y., Zang, J. Y., Zhu, L., Guo, Y. Z. & Liu, B. L., Jul 2004, In : Journal of Labelled Compounds and Radiopharmaceuticals. 47, 8, p. 513-521 9 p.

Research output: Contribution to journalArticle

Carbon Monoxide
Complex Mixtures
Imaging techniques
Thin layer chromatography
Myocardial Perfusion Imaging
2002
1 Citation (Scopus)
Germanium
germanium
synthesis