• 919 Citations
  • 13 h-Index
20062019

Research output per year

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Research Output

  • 919 Citations
  • 13 h-Index
  • 17 Article
  • 1 Comment/debate
  • 1 Letter
  • 1 Review article
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Article
2019

Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice

Wang, K. W., Zhan, X., McAlpine, W., Zhang, Z., Choi, J. H., Shi, H., Misawa, T., Yue, T., Zhang Ph.D., D-W., Wang, Y., Ludwig, S., Russell, J., Tang, M., Li, X., Murray, A. R., Moresco, E. M. Y., Turer, E. E. & Beutler, B., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 166, 23, p. 11380-11389 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR

Deng, M., Guo, H., Tam, J. W., Johnson, B. M., Brickey, W. J., New, J. S., Lenox, A., Shi, H., Golenbock, D. T., Koller, B. H., McKinnon, K. P., Beutler, B. & Ting, J. P. Y., Dec 1 2019, In : Journal of Experimental Medicine. 216, 12, p. 2838-2853 16 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2018

Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti–PD-L1 to eliminate melanoma in mice

Wang, Y., Su, L., Morin, M. D., Jones, B. T., Mifune, Y., Shi, H., Wang, K. W., Zhan, X., Liu, A., Wang, J., Li, X., Tang, M., Ludwig, S., Hildebrand, S., Zhou, K., Siegwart, D. J., Moresco, E. M. Y., Zhang, H., Boger, D. L. & Beutler, B., Sep 11 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 37, p. E8698-E8706

Research output: Contribution to journalArticle

19 Scopus citations

Diprovocims: A New and Exceptionally Potent Class of Toll-like Receptor Agonists

Morin, M. D., Wang, Y., Jones, B. T., Mifune, Y., Su, L., Shi, H-X., Moresco, E. M. Y., Zhang, H., Beutler, B. A. & Boger, D. L., Jan 1 2018, (Accepted/In press) In : Journal of the American Chemical Society.

Research output: Contribution to journalArticle

7 Scopus citations
2016

Erratum: TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS (Proceedings of the National Academy of Sciences of the United States of America (2016) 113 (E884-E893))

Wang, Y., Su, L., Morin, M. D., Jones, B. T., Whitby, L. R., Surakattula, M. M. R. P., Huang, H., Shi, H., Choi, J. H., Wang, K. W., Moresco, E. M. Y., Berger, M., Zhan, X., Zhang, H., Boger, D. L. & Beutler, B., Apr 5 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 14, p. E2096

Research output: Contribution to journalArticle

3 Scopus citations

K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria

Groß, C. J., Mishra, R., Schneider, K. S., Médard, G., Wettmarshausen, J., Dittlein, D. C., Shi, H., Gorka, O., Koenig, P. A., Fromm, S., Magnani, G., Ćiković, T., Hartjes, L., Smollich, J., Robertson, A. A. B., Cooper, M. A., Schmidt-Supprian, M., Schuster, M., Schroder, K., Broz, P. & 7 others, Traidl-Hoffmann, C., Beutler, B., Kuster, B., Ruland, J., Schneider, S., Perocchi, F. & Groß, O., Oct 18 2016, In : Immunity. 45, 4, p. 761-773 13 p.

Research output: Contribution to journalArticle

86 Scopus citations

TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS

Wang, Y., Su, L., Morin, M. D., Jones, B. T., Whitby, L. R., Surakattula, M. M. R. P., Huang, H., Shi, H., Choi, J. H., Wang, K. W., Moresco, E. M. Y., Berger, M., Zhan, X., Zhang, H., Boger, D. L. & Beutler, B., Feb 16 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 7, p. E884-E893

Research output: Contribution to journalArticle

54 Scopus citations
2015

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

Shi, H., Wang, Y., Li, X., Zhan, X., Tang, M., Fina, M., Su, L., Pratt, D., Bu, C. H., Hildebrand, S., Lyon, S., Scott, L., Quan, J., Sun, Q., Russell, J., Arnett, S., Jurek, P., Chen, D., Kravchenko, V. V., Mathison, J. C. & 4 others, Moresco, E. M. Y., Monson, N. L., Ulevitch, R. J. & Beutler, B., Dec 7 2015, (Accepted/In press) In : Nature Immunology.

Research output: Contribution to journalArticle

182 Scopus citations

Real-time resolution of point mutations that cause phenovariance in mice

Wang, T., Zhan, X., Bua, C. H., Lyona, S., Pratta, D., Hildebrand, S., Choi, J. H., Zhang, Z., Zeng, M., Wang, K. W., Turer, E. E., Chen, Z., Zhang Ph.D., D-W., Yue, T., Wang, Y., Shi, H-X., Wang, J., Sun, L., SoRelle, J., McAlpine, W. & 28 others, Hutchins, N., Zhan, X., Fin, M., Gobert, R., Quan, J., Kreutzer, M., Arnett, S., Hawkins, K., Leach, A., Tate, C., Daniel, C., Reyna, C., Prince, L., Davis, S., Purrington, J., Bearden, R., Weatherly, J., White, D., Russell, J. L., Sun, Q., Tang, M., Li, X., Scott, L., Moresco, E. M. Y., McInerney, G. M., Karlsson Hedestam, G. B., Xie, Y. & Beutler, B. A., Feb 3 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 5, p. E440-E449

Research output: Contribution to journalArticle

34 Scopus citations
2012

iRhom2 is required for the secretion of mouse TNFα

Siggs, O. M., Xiao, N., Wang, Y., Shi, H., Tomisato, W., Li, X., Xia, Y. & Beutler, B., Jun 14 2012, In : Blood. 119, 24, p. 5769-5771 3 p.

Research output: Contribution to journalArticle

52 Scopus citations
2011

Mitochondrial ubiquitin ligase MARCH5 promotes TLR7 signaling by attenuating TANK action

Shi, H. X., Liu, X., Wang, Q., Tang, P. P., Liu, X. Y., Shan, Y. F. & Wang, C., May 1 2011, In : PLoS pathogens. 7, 5, e1002057.

Research output: Contribution to journalArticle

38 Scopus citations
2010

Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification

Shi, H. X., Yang, K., Liu, X., Liu, X. Y., Wei, B., Shan, Y. F., Zhu, L. H. & Wang, C., May 1 2010, In : Molecular and cellular biology. 30, 10, p. 2424-2436 13 p.

Research output: Contribution to journalArticle

128 Scopus citations

Tom70 mediates activation of interferon regulatory factor 3 on mitochondria

Liu, X. Y., Wei, B., Shi, H. X., Shan, Y. F. & Wang, C., Sep 1 2010, In : Cell Research. 20, 9, p. 994-1011 18 p.

Research output: Contribution to journalArticle

60 Scopus citations
2009

TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response

Yang, K., Shi, H. X., Liu, X. Y., Shan, Y. F., Wei, B., Chen, S. & Wang, C., Mar 15 2009, In : Journal of Immunology. 182, 6, p. 3782-3792 11 p.

Research output: Contribution to journalArticle

111 Scopus citations
2007

UXT is a novel and essential cofactor in the NF-κB transcriptional enhanceosome

Sun, S., Tang, Y., Lou, X., Zhu, L., Yang, K., Zhang, B., Shi, H. & Wang, C., Jul 16 2007, In : Journal of Cell Biology. 178, 2, p. 231-244 14 p.

Research output: Contribution to journalArticle

38 Scopus citations
2006

An ankyrin repeat-containing protein, characterized as a ubiquitin ligase, is closely associated with membrane-enclosed organelles and required for pollen germination and pollen tube growth in lily

Huang, J., Chen, F., Del Casino, C., Autino, A., Shen, M., Yuan, S., Peng, J., Shi, H., Wang, C., Cresti, M. & Li, Y., Apr 1 2006, In : Plant Physiology. 140, 4, p. 1374-1383 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells

Yang, K., Shi, H., Qi, R., Sun, S., Tang, Y., Zhang, B. & Wang, C., Mar 1 2006, In : Molecular biology of the cell. 17, 3, p. 1461-1471 11 p.

Research output: Contribution to journalArticle

64 Scopus citations