Helen C Lai

  • 839 Citations
  • 11 h-Index
20012020

Research output per year

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Research Output

  • 839 Citations
  • 11 h-Index
  • 12 Article
  • 2 Review article
  • 1 Chapter
  • 1 Short survey
2020

Comparative transcriptomic analyses of developing melanocortin neurons reveal new regulators for the anorexigenic neuron identity

Chen, X., Wyler, S. C., Li, L., Arnold, A. G., Wan, R., Jia, L., Landy, M. A., Lai, H. C., Xu, P. & Liu, C., Apr 15 2020, In : Journal of Neuroscience. 40, 16, p. 3165-3177 13 p.

Research output: Contribution to journalArticle

Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates

Faure, L., Wang, Y., Kastriti, M. E., Fontanet, P., Cheung, K. K. Y., Petitpré, C., Wu, H., Sun, L. L., Runge, K., Croci, L., Landy, M. A., Lai, H. C., Consalez, G. G., de Chevigny, A., Lallemend, F., Adameyko, I. & Hadjab, S., Dec 1 2020, In : Nature communications. 11, 1, 4175.

Research output: Contribution to journalArticle

Open Access
2019

PRDM12 Is Required for Initiation of the Nociceptive Neuron Lineage during Neurogenesis

Bartesaghi, L., Wang, Y., Fontanet, P., Wanderoy, S., Berger, F., Wu, H., Akkuratova, N., Bouçanova, F., Médard, J. J., Petitpré, C., Landy, M. A., Zhang, M. D., Harrer, P., Stendel, C., Stucka, R., Dusl, M., Kastriti, M. E., Croci, L., Lai, H. C., Consalez, G. G. & 7 others, Pattyn, A., Ernfors, P., Senderek, J., Adameyko, I., Lallemend, F., Hadjab, S. & Chrast, R., Mar 26 2019, In : Cell Reports. 26, 13, p. 3484-3492.e4

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2016

Making sense out of spinal cord somatosensory development

Lai, H. C., Seal, R. P. & Johnson, J. E., Oct 1 2016, In : Development (Cambridge). 143, 19, p. 3434-3448 15 p.

Research output: Contribution to journalReview article

52 Scopus citations
2015

Origin of a Non-Clarke's Column Division of the Dorsal Spinocerebellar Tract and the Role of Caudal Proprioceptive Neurons in Motor Function

Yuengert, R., Hori, K., Kibodeaux, E. E., McClellan, J. X., Morales, J. E., Huang, T. W. P., Neul, J. L. & Lai, H. C., Nov 10 2015, In : Cell Reports. 13, 6, p. 1258-1271 14 p.

Research output: Contribution to journalArticle

14 Scopus citations
2013

bHLH Factors in Neurogenesis and Neuronal Subtype Specification

Lai, H. C., Meredith, D. M. & Johnson, J. E., May 2013, Comprehensive Developmental Neuroscience: Patterning and Cell Type Specification in the Developing CNS and PNS. Elsevier Inc., p. 333-354 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Prdm13 Mediates the Balance of Inhibitory and Excitatory Neurons in Somatosensory Circuits

Chang, J. C., Meredith, D. M., Mayer, P. R., Borromeo, M. D., Lai, H. C., Ou, Y. H. & Johnson, J. E., Apr 29 2013, In : Developmental Cell. 25, 2, p. 182-195 14 p.

Research output: Contribution to journalArticle

33 Scopus citations

Transcription factor Sox11 is essential for both embryonic and adult neurogenesis

Wang, Y., Lin, L., Lai, H., Parada, L. F. & Lei, L., Jun 2013, In : Developmental Dynamics. 242, 6, p. 638-653 16 p.

Research output: Contribution to journalArticle

45 Scopus citations
2011

In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord

Lai, H. C., Klisch, T. J., Roberts, R., Zoghbi, H. Y. & Johnson, J. E., Jul 27 2011, In : Journal of Neuroscience. 31, 30, p. 10859-10871 13 p.

Research output: Contribution to journalArticle

37 Scopus citations
2008

Neurogenesis or Neuronal Specification: Phosphorylation Strikes Again!

Lai, H. C. & Johnson, J. E., Apr 10 2008, In : Neuron. 58, 1, p. 3-5 3 p.

Research output: Contribution to journalShort survey

3 Scopus citations
2007

HP1α guides neuronal fate by timing E2F-targeted genes silencing during terminal differentiation

Panteleeva, I., Boutillier, S., See, V., Spiller, D. G., Rouaux, C., Almouzni, G., Bailly, D., Maison, C., Lai, H. C., Loeffler, J. P. & Boutillier, A. L., Aug 8 2007, In : EMBO Journal. 26, 15, p. 3616-3628 13 p.

Research output: Contribution to journalArticle

41 Scopus citations

Structure prediction for the down state of a potassium channel voltage sensor

Grabe, M., Lai, H. C., Jain, M., Nung Jan, Y. & Yeh Jan, L., Feb 1 2007, In : Nature. 445, 7127, p. 550-553 4 p.

Research output: Contribution to journalArticle

61 Scopus citations
2006

The distribution and targeting of neuronal voltage-gated ion channels

Lai, H. C. & Jan, L. Y., Jul 1 2006, In : Nature Reviews Neuroscience. 7, 7, p. 548-562 15 p.

Research output: Contribution to journalReview article

312 Scopus citations
2005

The S4 voltage sensor packs against the pore domain in the KAT1 voltage-gated potassium channel

Lai, H. C., Grabe, M., Yuh, N. J. & Lily, Y. J., Aug 4 2005, In : Neuron. 47, 3, p. 395-406 12 p.

Research output: Contribution to journalArticle

42 Scopus citations
2002

A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism

Serber, Z., Lai, H. C., Yang, A., Ou, H. D., Sigal, M. S., Kelly, A. E., Darimont, B. D., Duijf, P. H. G., Van Bokhoven, H., McKeon, F. & Dötsch, V., Dec 2002, In : Molecular and cellular biology. 22, 24, p. 8601-8611 11 p.

Research output: Contribution to journalArticle

156 Scopus citations
2001

Efficient identification of amino acid types for fast protein backbone assignments

Ou, H. D., Lai, H. C., Serber, Z. & Dötsch, V., Dec 24 2001, In : Journal of Biomolecular NMR. 21, 3, p. 269-273 5 p.

Research output: Contribution to journalArticle

28 Scopus citations