If you made any changes in Pure, your changes will be visible here soon.

Research Output 1999 2019

  • 716 Citations
  • 11 h-Index
  • 20 Article
  • 1 Short survey
Filter
Article
2019

Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice

Wang, K. W., Zhan, X., McAlpine, W., Zhang, Z., Choi, J. H., Shi, H., Misawa, T., Yue, T., Zhang Ph.D., D-W., Wang, Y., Ludwig, S., Russell, J., Tang, M., Li, X., Murray, A. R., Moresco, E. M. Y., Turer, E. E. & Beutler, B., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 166, 23, p. 11380-11389 10 p.

Research output: Contribution to journalArticle

Dextran Sulfate
Toll-Like Receptors
Regulatory T-Lymphocytes
Colitis
Dendritic Cells
1 Citation (Scopus)

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

Choi, J. H., Zhong, X., McAlpine, W., Liao, T. C., Zhang Ph.D., D-W., Fang, B., Russell, J., Ludwig, S., Nair-Gill, E., Zhang, Z., Wang, K. W., Misawa, T., Zhan, X., Choi, M., Wang, T., Li, X., Tang, M., Sun, Q., Yu, L., Murray, A. R. & 2 others, Moresco, E. Y. & Beutler, B., Jan 1 2019, In : Science. 364, 6440, eaau0812.

Research output: Contribution to journalArticle

Lymphopoiesis
Catenins
Wnt2 Protein
Ethylnitrosourea
Wnt Signaling Pathway
2018
2 Citations (Scopus)

A viable hypomorphic Arnt2 mutation causes hyperphagic obesity, diabetes and hepatic steatosis

Turer, E. E., San Miguel, M., Wang, K. W., McAlpine, W., Ou, F., Li, X., Tang, M., Zang, Z., Wang, J., Hayse, B., Evers, B., Zhan, X., Russell, J. L. & Beutler, B. A., Dec 18 2018, In : Disease models & mechanisms. 11, 12

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptor Nuclear Translocator
Medical problems
Clustered Regularly Interspaced Short Palindromic Repeats
Obesity
Mutation
2 Citations (Scopus)

Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function

McAlpine, W., Sun, L., Wang, K. W., Liu, A., Jain, R., Miguel, M. S., Wang, J., Zhang, Z., Hayse, B., McAlpine, S. G., Choi, J. H., Zhong, X., Ludwig, S., Russell, J. L., Zhan, X., Choi, M., Li, X., Tang, M., Moresco, E. M. Y., Beutler, B. A. & 1 others, Turer, E. E., Dec 4 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 49, p. E11523-E11531

Research output: Contribution to journalArticle

Toll-Like Receptors
Autoimmunity
Ligands
Phagosomes
Dextran Sulfate
4 Citations (Scopus)

Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors

Wang, Y., Cao, L., Lee, C. Y., Matsuo, T., Wu, K., Asher, G., Tang, L., Saitoh, T., Russell, J. L., Klewe-Nebenius, D., Wang, L., Soya, S., Hasegawa, E., Chérasse, Y., Zhou, J., Li, Y., Wang, T., Zhan, X., Miyoshi, C., Irukayama, Y. & 13 others, Cao, J., Meeks, J., Gautron, L., Wang, Z., Sakurai, K., Funato, H., Sakurai, T., Yanagisawa, M., Nagase, H., Kobayakawa, R., Kobayakawa, K., Beutler, B. A. & Liu, Q., Dec 1 2018, In : Nature Communications. 9, 1, 4324.

Research output: Contribution to journalArticle

fear
Instinct
odors
predators
Genetic Testing
10 Citations (Scopus)

Probability of phenotypically detectable protein damage by ENU-induced mutations in the Mutagenetix database

Wang, T., Bu, C. H., Hildebrand, S., Jia, G., Siggs, O. M., Lyon, S., Pratt, D., Scott, L., Russell, J., Ludwig, S., Murray, A. R., Moresco, E. M. Y. & Beutler, B., Dec 1 2018, In : Nature Communications. 9, 1, 441.

Research output: Contribution to journalArticle

mutations
Genes
Databases
damage
proteins

The class i myosin MYO1D binds to lipid and protects against colitis

McAlpine, W., Wang, K. W., Choi, J. H., Miguel, M. S., McAlpine, S. G., Russell, J., Ludwig, S., Li, X., Tang, M., Zhan, X., Choi, M., Wang, T., Bu, C. H., Murray, A. R., Moresco, E. M. Y., Turer, E. E. & Beutler, B., Sep 1 2018, In : DMM Disease Models and Mechanisms. 11, 9, dmm035923.

Research output: Contribution to journalArticle

Dextran Sulfate
Colitis
Myosins
Myosin Type I
Ethylnitrosourea
2015
158 Citations (Scopus)

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

Shi, H., Wang, Y., Li, X., Zhan, X., Tang, M., Fina, M., Su, L., Pratt, D., Bu, C. H., Hildebrand, S., Lyon, S., Scott, L., Quan, J., Sun, Q., Russell, J., Arnett, S., Jurek, P., Chen, D., Kravchenko, V. V., Mathison, J. C. & 4 others, Moresco, E. M. Y., Monson, N. L., Ulevitch, R. J. & Beutler, B., Dec 7 2015, (Accepted/In press) In : Nature Immunology.

Research output: Contribution to journalArticle

Inflammasomes
Mitosis
Caspase 1
Interleukin-18
Protein-Serine-Threonine Kinases
29 Citations (Scopus)

Real-time resolution of point mutations that cause phenovariance in mice

Wang, T., Zhan, X., Bua, C. H., Lyona, S., Pratta, D., Hildebrand, S., Choi, J. H., Zhang, Z., Zeng, M., Wang, K. W., Turer, E. E., Chen, Z., Zhang Ph.D., D-W., Yue, T., Wang, Y., Shi, H-X., Wang, J., Sun, L., SoRelle, J., McAlpine, W. & 28 others, Hutchins, N., Zhan, X., Fin, M., Gobert, R., Quan, J., Kreutzer, M., Arnett, S., Hawkins, K., Leach, A., Tate, C., Daniel, C., Reyna, C., Prince, L., Davis, S., Purrington, J., Bearden, R., Weatherly, J., White, D., Russell, J. L., Sun, Q., Tang, M., Li, X., Scott, L., Moresco, E. M. Y., McInerney, G. M., Karlsson Hedestam, G. B., Xie, Y. & Beutler, B. A., Feb 3 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 5, p. E440-E449

Research output: Contribution to journalArticle

Point Mutation
Mutation
Ethylnitrosourea
Phenotype
High-Throughput Nucleotide Sequencing
2012
18 Citations (Scopus)

Coupling hippocampal neurogenesis to brain ph through proneurogenic small molecules that regulate proton sensing G protein-coupled receptors

Schneider, J. W., Goetsch, S. C., Leng, X., Ludwig, S. M., Russell, J. L., Yang, C. P. & Zhang, Q. J., Jul 18 2012, In : ACS Chemical Neuroscience. 3, 7, p. 557-568 12 p.

Research output: Contribution to journalArticle

Neurogenesis
G-Protein-Coupled Receptors
Protons
Brain
Neural Stem Cells
29 Citations (Scopus)

Regulated expression of pH sensing G protein-coupled receptor-68 identified through chemical biology defines a new drug target for ischemic heart disease

Russell, J. L., Goetsch, S. C., Aguilar, H. R., Coe, H., Luo, X., Liu, N., Van Rooij, E., Frantz, D. E. & Schneider, J. W., Jun 15 2012, In : ACS Chemical Biology. 7, 6, p. 1077-1083 7 p.

Research output: Contribution to journalArticle

Isoxazoles
Myocardial Ischemia
Pericardium
Pharmaceutical Preparations
Protons
31 Citations (Scopus)

Targeting native adult heart progenitors with cardiogenic small molecules

Russell, J. L., Goetsch, S. C., Aguilar, H. R., Frantz, D. E. & Schneider, J. W., Jun 15 2012, In : ACS Chemical Biology. 7, 6, p. 1067-1076 10 p.

Research output: Contribution to journalArticle

Isoxazoles
Molecules
Muscle
Pericardium
Gene expression
2011
98 Citations (Scopus)

A dynamic notch injury response activates epicardium and contributes to fibrosis repair.

Russell, J. L., Goetsch, S. C., Gaiano, N. R., Hill, J. A., Olson, E. N. & Schneider, J. W., Jan 7 2011, In : Circulation Research. 108, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

Pericardium
Fibrosis
Wounds and Injuries
Severe Combined Immunodeficiency
Epithelial-Mesenchymal Transition
22 Citations (Scopus)

A small molecule differentiation inducer increases insulin production by pancreatic β cells

Dioum, E. M., Osborne, J. K., Goetsch, S., Russell, J., Schneider, J. W. & Cobb, M. H., Dec 20 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 51, p. 20713-20718 6 p.

Research output: Contribution to journalArticle

Isoxazoles
Insulin
Histones
Transferases
Histone Deacetylases
2006
10 Citations (Scopus)

E2F1 suppresses skin carcinogenesis via the ARF-p53 pathway

Russell, J. L., Weaks, R. L., Berton, T. R. & Johnson, D. G., Feb 9 2006, In : Oncogene. 25, 6, p. 867-876 10 p.

Research output: Contribution to journalArticle

Carcinogenesis
Skin
Transgenic Mice
Neoplasms
E2F1 Transcription Factor
10 Citations (Scopus)

Molecular signatures define myogenic stem cell populations

Martin, C. M., Russell, J. L., Ferdous, A. & Garry, D. J., Mar 2006, In : Stem Cell Reviews. 2, 1, p. 37-42 6 p.

Research output: Contribution to journalArticle

Stem Cells
Skeletal Muscle
Adult Stem Cells
Population
Wounds and Injuries
2002
66 Citations (Scopus)

ARF differentially modulates apoptosis induced by E2F1 and Myc

Russell, J. L., Powers, J. T., Rounbehler, R. J., Rogers, P. M., Conti, C. J. & Johnson, D. G., Feb 26 2002, In : Molecular and Cellular Biology. 22, 5, p. 1360-1368 9 p.

Research output: Contribution to journalArticle

Apoptosis
E2F1 Transcription Factor
S Phase
Epidermis
Neoplasms
2000
77 Citations (Scopus)

E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo

Wang, D., Russell, J. L. & Johnson, D. G., May 1 2000, In : Molecular and Cellular Biology. 20, 10, p. 3417-3424 8 p.

Research output: Contribution to journalArticle

Transgenic Mice
Retinoblastoma
Keratin-5
Carcinogenesis
Neoplasms
1999
129 Citations (Scopus)

E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model

Pierce, A. M., Schneider-Broussard, R., Gimenez-Conti, I. B., Russell, J. L., Conti, C. J. & Johnson, D. G., Jan 1 1999, In : Molecular and Cellular Biology. 19, 9, p. 6408-6414 7 p.

Research output: Contribution to journalArticle

Keratin-5
Transgenic Mice
Skin
Carcinogenesis
Neoplasms
19 Citations (Scopus)

Increased expression of mutated Ha-ras during premalignant progression in SENCAR mouse skin

Rodriguez-Puebla, M. L., LaCava, M., Bolontrade, M. F., Russell, J. & Conti, C. J., Nov 22 1999, In : Molecular Carcinogenesis. 26, 3, p. 150-156 7 p.

Research output: Contribution to journalArticle

Inbred SENCAR Mouse
Alleles
Skin
ras Proteins
Guanine Nucleotides