• 2153 Citations
  • 12 h-Index
20082020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Amino Acid Sensing: Architecture of mTORC1 on the Lysosome Surface

Peng, W. & Jewell, J. L., Jan 20 2020, In : Current Biology. 30, 2, p. R89-R91

Research output: Contribution to journalArticle

1 Scopus citations

Glutamine and asparagine activate mTORC1 independently of Rag GTPases

Meng, D., Yang, Q., Wang, H., Melick, C. H., Navlani, R., Frank, A. R. & Jewell, J. L., Mar 6 2020, In : Journal of Biological Chemistry. 295, 10, p. 2890-2899 10 p.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations
2019

Clearing debris

Meng, D. & Jewell, J. L., Aug 1 2019, In : Nature chemical biology. 15, 8, p. 760-761 2 p.

Research output: Contribution to journalComment/debate

GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor

Jewell, J. L., Fu, V., Hong, A. W., Yu, F. X., Meng, D., Melick, C. H., Wang, H., Lam, W. L. M., Yuan, H. X., Taylor, S. S. & Guan, K. L., May 21 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

mTOR signaling in stem and progenitor cells

Meng, D., Frank, A. R. & Jewell, J. L., Jan 2018, In : Development (Cambridge). 145, 1, dev152595.

Research output: Contribution to journalReview article

37 Scopus citations
2015

Differential regulation of mTORC1 by leucine and glutamine

Jewell, J. L., Kim, Y. C., Russell, R. C., Yu, F. X., Park, H. W., Plouffe, S. W., Tagliabracci, V. S. & Guan, K. L., Jan 9 2015, In : Science. 347, 6218, p. 194-198 5 p.

Research output: Contribution to journalArticle

277 Scopus citations

Micro(RNA) managing by mTORC1

Jewell, J. L., Flores, F. & Guan, K. L., Feb 19 2015, In : Molecular cell. 57, 4, p. 575-576 2 p.

Research output: Contribution to journalShort survey

3 Scopus citations

NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition

Yuan, H. X., Wang, Z., Yu, F. X., Li, F., Russell, R. C., Jewell, J. L. & Guan, K. L., Nov 15 2015, In : Genes and Development. 29, 22, p. 2362-2376 15 p.

Research output: Contribution to journalArticle

18 Scopus citations
2014

Rag GTPases

Jewell, J. L. & Guan, K. L., May 1 2014, Ras Superfamily Small G Proteins: Biology and Mechanisms 2: Transport. Springer International Publishing, p. 277-292 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Rag GTPases are cardioprotective by regulating lysosomal function

Kim, Y. C., Park, H. W., Sciarretta, S., Mo, J. S., Jewell, J. L., Russell, R. C., Wu, X., Sadoshima, J. & Guan, K. L., Jul 1 2014, In : Nature communications. 5, 4241.

Research output: Contribution to journalArticle

44 Scopus citations
2013

Amino acid signalling upstream of mTOR

Jewell, J. L., Russell, R. C. & Guan, K. L., Mar 1 2013, In : Nature Reviews Molecular Cell Biology. 14, 3, p. 133-139 7 p.

Research output: Contribution to journalArticle

444 Scopus citations

Nutrient signaling to mTOR and cell growth

Jewell, J. L. & Guan, K. L., May 1 2013, In : Trends in Biochemical Sciences. 38, 5, p. 233-242 10 p.

Research output: Contribution to journalReview article

205 Scopus citations

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation

Yu, F. X., Zhang, Y., Park, H. W., Jewell, J. L., Chen, Q., Deng, Y., Pan, D., Taylor, S. S., Lai, Z. C. & Guan, K. L., Feb 1 2013, In : Genes and Development. 27, 11, p. 1223-1232 10 p.

Research output: Contribution to journalArticle

153 Scopus citations
2012

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

Yu, F. X., Zhao, B., Panupinthu, N., Jewell, J. L., Lian, I., Wang, L. H., Zhao, J., Yuan, H., Tumaneng, K., Li, H., Fu, X. D., Mills, G. B. & Guan, K. L., Aug 17 2012, In : Cell. 150, 4, p. 780-791 12 p.

Research output: Contribution to journalArticle

738 Scopus citations
2011

Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis

Jewell, J. L., Oh, E., Ramalingam, L., Kalwat, M. A., Tagliabracci, V. S., Tackett, L., Elmendorf, J. S. & Thurmond, D. C., Apr 4 2011, In : Journal of Cell Biology. 193, 1, p. 185-199 15 p.

Research output: Contribution to journalArticle

46 Scopus citations
2010
73 Scopus citations
2008

Filamentous actin regulates insulin exocytosis through direct interaction with Syntaxin 4

Jewell, J. L., Luo, W., Oh, E., Wang, Z. & Thurmond, D. C., Apr 18 2008, In : Journal of Biological Chemistry. 283, 16, p. 10716-10726 11 p.

Research output: Contribution to journalArticle

76 Scopus citations

The tyrosine phosphorylation of Munc18c induces a switch in binding specificity from syntaxin 4 to Doc2β

Jewell, J. L., Oh, E., Bennett, S. M., Meroueh, S. O. & Thurmond, D. C., Aug 1 2008, In : Journal of Biological Chemistry. 283, 31, p. 21734-21746 13 p.

Research output: Contribution to journalArticle

35 Scopus citations