• 11409 Citations
  • 57 h-Index
1977 …2020

Research output per year

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Research Output

Abrogating TNF-α expression prevents bystander destruction of normal tissues during iNOS-mediated elimination of intraocular tumors

Coursey, T. G., Chen, P. W. & Niederkorn, J. Y., Apr 1 2011, In : Cancer Research. 71, 7, p. 2445-2454 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Abrogation of anterior–chamber-induced suppression of delayed–type hypersensitivity responses by monoclonal anti–I–J antibodies

Niederkorn, J. Y., Waltenbaugh, C. & Streilein, J. W., Jun 1984, In : Transplantation. 37, 6, p. 623-625 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Acanthamoeba keratitis

McCulley, J. P., Alizadeh, H. & Niederkorn, J. Y., Jan 1 1995, In : CLAO Journal. 21, 1, p. 73-76 4 p.

Research output: Contribution to journalArticle

40 Scopus citations

Acanthamoeba keratitis primes humoral but not cellular immune responses

Leher, H. F., Alizadeh, H. & Niederkorn, J. Y., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3, p. S416

Research output: Contribution to journalArticle

Acceptance of H-Y-disparate corneal grafts despite concomitant immunization of the recipient

He, Y. G., Ross, J., Callanan, D. & Niederkorn, J. Y., Jun 1991, In : Transplantation. 51, 6, p. 1258-1262 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Adaptive immune responses to Acanthamoeba cysts

McClellan, K., Howard, K., Mayhew, E., Niederkorn, J. Y. & Alizadeh, H., Jan 1 2002, In : Experimental Eye Research. 75, 3, p. 285-293 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Adoptive transfer of immunity to intraocular tumors in mice

Niederkorn, J. Y. & Streilein, J. W., Jan 1 1984, In : Investigative Ophthalmology and Visual Science. 25, 3, p. 336-342 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Advances on non-CD4 + Foxp3+ T regulatory cells: CD8+, type 1, and double negative T regulatory cells in organ transplantation

Ligocki, A. J. & Niederkorn, J. Y., Aug 1 2015, In : Transplantation. 99, 8, p. 1553-1559 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Age-related T-cell cytokine profile parallels corneal disease severity in Sjögren's syndrome-like keratoconjunctivitis sicca in CD25KO mice

de Paiva, C. S., Hwang, C. S., Pitcher, J. D., Pangelinan, S. B., Rahimy, E., Chen, W., Yoon, K. C., Farley, W. J., Niederkorn, J. Y., Stern, M. E., Li, D. Q. & Pflugfelder, S. C., Feb 2010, In : Rheumatology. 49, 2, p. 246-258 13 p., kep357.

Research output: Contribution to journalArticle

60 Scopus citations

Allergic airway hyperreactivity increases the risk for corneal allograft rejection

Niederkorn, J. Y., Chen, P. W., Mellon, J., Stevens, C. & Mayhew, E., May 1 2009, In : American Journal of Transplantation. 9, 5, p. 1017-1026 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Allergic conjunctivitis exacerbates corneal allograft rejection by activating Th1 and Th2 alloimmune responses

Niederkorn, J. Y., Chen, P. W., Mellon, J., Stevens, C. & Mayhew, E., Jun 1 2010, In : Journal of Immunology. 184, 11, p. 6076-6083 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Allergic conjunctivitis renders CD4+ T cells resistant to T regulatory cells and exacerbates corneal allograft rejection

Reyes, N. J., Chen, P. W. & Niederkorn, J. Y., May 1 2013, In : American Journal of Transplantation. 13, 5, p. 1181-1192 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Alloantigen presentation to the anterior chamber of the eye subverts specific in vitro cell-mediated immune responses

Whittum, J. A., Niederkorn, J. Y. & Streilein, J. W., Oct 1982, In : Transplantation. 34, 4, p. 190-195 6 p.

Research output: Contribution to journalArticle

12 Scopus citations
15 Scopus citations
85 Scopus citations

A mechanism for anti-asialo GM 1 antibody-induced anaphylactoid response in mice infected with Trichinella pseudospiralis

Stewart, G. L., Niederkorn, J. Y., Ghazizadeh, S., Mayhew, E. & Ahanotu, E., Jan 1 1989, In : Journal of Parasitology. 75, 5, p. 780-786 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Analysis of antibody production induced by allogeneic tumor cells inoculated into the anterior chamber of the eye

Niederkorn, J. Y. & Streilein, J. W., Jun 1982, In : Transplantation. 33, 6, p. 573-577 5 p.

Research output: Contribution to journalArticle

40 Scopus citations

Angiostatin produced by certain primary uveal melanoma cell lines impedes the development of liver metastases

Apte, R. S., Niederkorn, J. Y., Mayhew, E. & Alizadeh, H., Dec 2001, In : Archives of Ophthalmology. 119, 12, p. 1805-1809 5 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

A novel role for TGF-β and IL-10 in the induction of immune privilege

D'Orazio, T. J. & Niederkorn, J. Y., Mar 1 1998, In : Journal of Immunology. 160, 5, p. 2089-2098 10 p.

Research output: Contribution to journalArticle

238 Scopus citations

Anterior chamber-associated immune deviation

Niederkorn, J. Y., Oct 28 1999, In : Chemical Immunology. 73, p. 59-71 13 p.

Research output: Contribution to journalReview article

27 Scopus citations

Anterior chamber-associated immune deviation and its impact on corneal allograft survival

Niederkorn, J. Y., Aug 1 2006, In : Current Opinion in Organ Transplantation. 11, 4, p. 360-365 6 p.

Research output: Contribution to journalReview article

25 Scopus citations

Anterior chamber-associated immune deviation promotes corneal allograft survival

Niederkorn, J. Y. & Mellon, J., Dec 1 1996, In : Investigative Ophthalmology and Visual Science. 37, 13, p. 2700-2707 8 p.

Research output: Contribution to journalArticle

106 Scopus citations

Antibody-dependent neutrophil-mediated killing of Acanthamoeba castellanii

Stewart, G. L., Shupe, K., Kim, I., Silvany, R. E., Alizadeh, H., McCulley, J. P. & Niederkorn, J. Y., Aug 1994, In : International Journal for Parasitology. 24, 5, p. 739-742 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Antigenic cross-reactivity among different microsporidan spores as determined by immunofluorescence.

Niederkorn, J. Y., Shadduck, J. A. & Weidner, E., Aug 1980, In : The Journal of parasitology. 66, 4, p. 675-677 3 p.

Research output: Contribution to journalArticle

27 Scopus citations
71 Scopus citations

Anti-leukocyte function-1 antibody treatment prevents the rejection of intraocular regressor tumors and their metastases

Li, X. Y., Mayhew, E. & Niederkorn, J. Y., Jan 1 1995, In : Current Eye Research. 14, 8, p. 719-726 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

A pig model of Acanthamoeba keratitis: Transmission via contaminated contact lenses

He, Y-G., McCulley, J. P., Alizadeh, H., Pidherney, M., Mellon, J., Ubelaker, J. E., Stewart, G. L., Silvany, R. E. & Niederkorn, J. Y., Jan 1 1992, In : Investigative Ophthalmology and Visual Science. 33, 1, p. 126-133 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Apoptosis and homeostasis in the eye

Niederkorn, J. Y., Jan 1 2011, Apoptosis: Physiology and Pathology. Cambridge University Press, p. 176-181 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Apoptosis as a mechanism of cytolysis of tumor cells by a pathogenic free- living amoeba

Alizadeh, H., Pidherney, M. S., McCulley, J. P. & Niederkorn, J. Y., Jan 1 1994, In : Infection and immunity. 62, 4, p. 1298-1303 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

Aqueous humor-borne factor upregulates Bcl-2 expression in corneal endothelial cells

Li, X. Y., De Marco, B. M., Mayhew, E. S. & Niederkorn, J. Y., Oct 23 1998, In : Current Eye Research. 17, 10, p. 970-978 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Are corneal cells susceptible to antibody-mediated killing in corneal allograft rejection?

Hargrave, S. L., Mayhew, E., Hegde, S. & Niederkorn, J., Jan 1 2003, In : Transplant Immunology. 11, 1, p. 79-89 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

A renewed appreciation for ocular immune privilege.

Niederkorn, J. Y., Aug 2005, In : Archivos de la Sociedad Española de Oftalmología. 80, 8, p. 437-438; 439-440

Research output: Contribution to journalEditorial

Open Access
3 Scopus citations

Association between NM23-H1 gene expression and metastasis of human uveal melanoma in an animal model

Ma, D., Luyten, G. P., Luider, T. M., Jager, M. J. & Niederkorn, J. Y., Oct 1 1996, In : Investigative Ophthalmology and Visual Science. 37, 11, p. 2293-2301 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Autoantibodies contribute to the immunopathogenesis of experimental dry eye disease.

Stern, M. E., Schaumburg, C. S., Siemasko, K. F., Gao, J., Wheeler, L. A., Grupe, D. A., De Paiva, C. S., Calder, V. L., Calonge, M., Niederkorn, J. Y. & Pflugfelder, S. C., Apr 2012, In : Investigative ophthalmology & visual science. 53, 4, p. 2062-2075 14 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Autoimmunity at the ocular surface: Pathogenesis and regulation

Stern, M. E., Schaumburg, C. S., Dana, R., Calonge, M., Niederkorn, J. Y. & Pflugfelder, S. C., Sep 1 2010, In : Mucosal Immunology. 3, 5, p. 425-442 18 p.

Research output: Contribution to journalReview article

62 Scopus citations

Capacity of simian virus 40 T antigen to induce self-tolerance but not immunological privilege in the anterior chamber of the eye

Ma, D., Comerford, S. A., Bellingham, D., Sambrook, J., Gething, M. J., Alizadeh, H., Anand, R., Mellon, J. & Niederkorn, J. Y., Mar 1994, In : Transplantation. 57, 5, p. 718-725 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

CD25+, interleukin-10-producing CD4+ T cells are required for suppressor cell production and immune privilege in the anterior chamber of the eye

Skelsey, M. E., Mayhew, E. & Niederkorn, J. Y., Sep 1 2003, In : Immunology. 110, 1, p. 18-29 12 p.

Research output: Contribution to journalArticle

62 Scopus citations

CD4+ T-cell-dependent tumour rejection in an immune-privileged environment requires macrophages

Dace, D. S., Chen, P. W. & Niederkorn, J. Y., Mar 1 2008, In : Immunology. 123, 3, p. 367-377 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

CD4+ T-cell-independent rejection of corneal allografts

Niederkorn, J. Y., Stevens, C., Mellon, J. & Mayhew, E., Apr 1 2006, In : Transplantation. 81, 8, p. 1171-1178 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

CD4+ T-cell-mediated mechanisms of corneal allograft rejection: Role of Fas-induced apoptosis

Hegde, S., Beauregard, C., Mayhew, E. & Niederkorn, J. Y., Jan 15 2005, In : Transplantation. 79, 1, p. 23-31 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

CD8+ cells regulate the T helper-17 response in an experimental murine model of sjögren syndrome

Zhang, X., Schaumburg, C. S., Coursey, T. G., Siemasko, K. F., Volpe, E. A., Gandhi, N. B., Li, D. Q., Niederkorn, J. Y., Stern, M. E., Pflugfelder, S. C. & De Paiva, C. S., Mar 2014, In : Mucosal Immunology. 7, 2, p. 417-427 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

CD8+ T cells circumvent immune privilege in the eye and mediate intraocular tumor rejection by a TNF-α-dependent mechanism

Dace, D. S., Chen, P. W. & Niederkorn, J. Y., May 15 2007, In : Journal of Immunology. 178, 10, p. 6115-6122 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Characteristics of rejection of orthotopic corneal allografts in the rat

Callanan, D., Peeler, J. & Niederkorn, J. Y., Feb 1988, In : Transplantation. 45, 2, p. 437-443 7 p.

Research output: Contribution to journalArticle

73 Scopus citations

Characterization and pathogenic potential of a soil isolate and an ocular isolate of acanthamoeba castellanii in relation to acanthamoeba keratitis

Klink, F. V., Alizadeh, H., Stewart, G. L., Pidherney, M. S., Silvany, R. E., He, Y., McCulley, J. P. & Niederkorn, J. Y., Jan 1 1992, In : Current Eye Research. 11, 12, p. 1207-1220 14 p.

Research output: Contribution to journalArticle

43 Scopus citations

Characterization of a plasminogen activator produced by Acanthamoeba castellanii

Mitra, M. M., Alizadeh, H., Gerard, R. D. & Niederkorn, J. Y., Jul 1995, In : Molecular and Biochemical Parasitology. 73, 1-2, p. 157-164 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

Characterization of intraocular tumors arising in transgenic mice

Anand, R., Ma, D., Alizadeh, H., Comerford, S. A., Sambrook, J. F., Gething -, M. J. H., McLean, I. W. & Niederkorn, J. Y., Jan 1 1994, In : Investigative Ophthalmology and Visual Science. 35, 9, p. 3533-3539 7 p.

Research output: Contribution to journalArticle

31 Scopus citations
102 Scopus citations

Chemotactic response of macrophages to Acanthamoeba castellanii antigen and antibody-dependent macrophage-mediated killing of the parasite

Stewart, G. L., Kim, I., Shupe, K., Alizadeh, H., Silvany, R., McCulley, J. P. & Niederkorn, J. Y., Oct 30 1992, In : Journal of Parasitology. 78, 5, p. 849-855 7 p.

Research output: Contribution to journalArticle

42 Scopus citations