• 11409 Citations
  • 57 h-Index
1977 …2020

Research output per year

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Research Output

2005

Cutting edge: Atopy promotes Th2 responses to alloantigens and increases the incidence and tempo of corneal allograft rejection

Beauregard, C., Stevens, C., Mayhew, E. & Niederkorn, J. Y., Jun 1 2005, In : Journal of Immunology. 174, 11, p. 6577-6581 5 p.

Research output: Contribution to journalArticle

Open Access
41 Scopus citations

Evaluation of ocular surface inflammation in the presence of dry eye and allergic conjunctival disease

Stern, M. E., Siemasko, K. F., Gao, J., Calonge, M., Niederkorn, J. Y. & Pflugfelder, S. C., Oct 1 2005, In : Ocular Surface. 3, 4, p. S161-S164

Research output: Contribution to journalArticle

30 Scopus citations

Failure of Acanthamoeba castellanii to produce intraocular infections

Clarke, D. W., Alizadeh, H. & Niederkorn, J. Y., Dec 1 2005, In : Investigative Ophthalmology and Visual Science. 46, 7, p. 2472-2478 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Immune privilege of the eye and fetus: Parallel universes?

Niederkorn, J. Y. & Wang, S., Nov 1 2005, In : Transplantation. 80, 9, p. 1139-1144 6 p.

Research output: Contribution to journalReview article

28 Scopus citations

Immunology of intraocular tumors

Niederkorn, J. Y. & Wang, S., Feb 1 2005, In : Ocular Immunology and Inflammation. 13, 1, p. 105-110 6 p.

Research output: Contribution to journalReview article

21 Scopus citations

Immunology of the ocular surface/corneal graft: What happens when immune vigilance goes awry?

Niederkorn, J. Y., Jul 21 2005, In : Asian Journal of Ophthalmology. 7, SUPPL. 1, p. 16-19 4 p.

Research output: Contribution to journalArticle

Immunosuppressive factors secreted by human amniotic epithelial cells

Li, H., Niederkorn, J. Y., Neelam, S., Mayhew, E., Word, R. A., McCulley, J. P. & Alizadeh, H., Mar 1 2005, In : Investigative Ophthalmology and Visual Science. 46, 3, p. 900-907 8 p.

Research output: Contribution to journalArticle

210 Scopus citations

Pathways of corneal and ocular surface inflammation: A perspective from the Cullen symposium

McDermott, A. M., Perez, V., Huang, A. J. W., Pflugfelder, S. C., Stern, M. E., Baudouin, C., Beuerman, R. W., Burns, A. R., Calder, V. L., Calonge, M., Chodosh, J., Coster, D. J., Dana, R., Hazlett, L. D., Jones, D. B., Kim, S. K., Knop, E., Li, D. Q., Mitchell, B. M., Niederkorn, J. Y. & 3 others, Pearlman, E., Wilhelmus, K. R. & Kurie, E., Oct 1 2005, In : Ocular Surface. 3, 4, p. S131-S138

Research output: Contribution to journalArticle

43 Scopus citations

Resistance and susceptibility of human uveal melanoma cells to TRAIL-induced apoptosis

Li, H., Niederkorn, J. Y., Neelam, S. & Alizadeh, H., May 1 2005, In : Archives of Ophthalmology. 123, 5, p. 654-661 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Role of contact lens wear, bacterial flora, and mannose-induced pathogenic protease in the pathogenesis of amoebic keratitis

Alizadeh, H., Neelam, S., Hurt, M. & Niederkorn, J. Y., Feb 1 2005, In : Infection and immunity. 73, 2, p. 1061-1068 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Role of interferon-γ in a mouse model of allergic conjunctivitis

Stern, M. E., Siemasko, K., Gao, J., Duong, A., Beauregard, C., Calder, V. & Niederkorn, J. Y., Sep 1 2005, In : Investigative Ophthalmology and Visual Science. 46, 9, p. 3239-3246 8 p.

Research output: Contribution to journalArticle

61 Scopus citations

The Th1/Th2 paradigm in ocular allergy

Stern, M. E., Siemasko, K. F. & Niederkorn, J. Y., Oct 2005, In : Current Opinion in Allergy and Clinical Immunology. 5, 5, p. 446-450 5 p.

Research output: Contribution to journalReview article

39 Scopus citations
2004

Expression and possible function of IL-2 and IL-15 receptors on human uveal melanoma cells

He, Y. G., Mayhew, E., Mellon, J. & Niederkorn, J. Y., Dec 1 2004, In : Investigative Ophthalmology and Visual Science. 45, 12, p. 4240-4246 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Fate of MHC-matched corneal allografts in Th1-deficient hosts

Hargrave, S. L., Hay, C., Mellon, J., Mayhew, E. & Niederkorn, J. Y., Apr 1 2004, In : Investigative Ophthalmology and Visual Science. 45, 4, p. 1188-1193 6 p.

Research output: Contribution to journalArticle

41 Scopus citations

Passing of a giant.

Niederkorn, J. Y., Jul 27 2004, In : Transplantation. 78, 2, p. 306-307 2 p.

Research output: Contribution to journalArticle

23 Scopus citations

Uveal melanoma expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptors and susceptibility to TRAIL-induced apoptosis

Ren, D. H., Mayhew, E., Hay, C., Li, H., Alizadeh, H. & Niederkorn, J. Y., Apr 1 2004, In : Investigative Ophthalmology and Visual Science. 45, 4, p. 1162-1168 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
2003

Are corneal cells susceptible to antibody-mediated killing in corneal allograft rejection?

Hargrave, S. L., Mayhew, E., Hegde, S. & Niederkorn, J., Jan 1 2003, In : Transplant Immunology. 11, 1, p. 79-89 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

CD25+, interleukin-10-producing CD4+ T cells are required for suppressor cell production and immune privilege in the anterior chamber of the eye

Skelsey, M. E., Mayhew, E. & Niederkorn, J. Y., Sep 1 2003, In : Immunology. 110, 1, p. 18-29 12 p.

Research output: Contribution to journalArticle

62 Scopus citations

Effects of mannose on Acanthamoeba castellanii proliferation and cytolytic ability to corneal epithelial cells

Hurt, M., Niederkorn, J. & Alizadeh, H., Aug 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 8, p. 3424-3431 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Immune privilege of the eye

Niederkorn, J. Y., Jan 1 2003, Animal Models of Human Inflammatory Skin Diseases. CRC Press, p. 143-154 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Mechanisms of immune privilege in the eye and hair follicle

Niederkorn, J. Y., Oct 2003, In : Journal of Investigative Dermatology Symposium Proceedings. 8, 2, p. 168-172 5 p.

Research output: Contribution to journalArticle

47 Scopus citations

Pathogenic Acanthamoeba spp. Secrete a Mannose-Induced Cytolytic Protein that Correlates with the Ability to Cause Disease

Hurt, M., Neelam, S., Niederkorn, J. & Alizadeh, H., Nov 2003, In : Infection and immunity. 71, 11, p. 6243-6255 13 p.

Research output: Contribution to journalArticle

63 Scopus citations

Preliminary findings in corneal allograft rejection in patients with keratoconus

Hargrave, S., Chu, Y., Mendelblatt, D., Mayhew, E. & Niederkorn, J., Apr 1 2003, In : American journal of ophthalmology. 135, 4, p. 452-460 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Reduction of liver metastasis of intraocular melanoma by interferon-β gene transfer

Alizadeh, H., Howard, K., Mellon, J., Mayhew, E., Rusciano, D. & Niederkorn, J. Y., Jul 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 7, p. 3042-3051 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Role of TRAIL and IFN-γ in CD4+ T cell-dependent tumor rejection in the anterior chamber of the eye

Wang, S., Boonman, Z. F. H. M., Li, H. C., He, Y., Jager, M. J., Toes, R. E. M. & Niederkorn, J. Y., Sep 15 2003, In : Journal of Immunology. 171, 6, p. 2789-2796 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Splenic B Cells Act as Antigen Presenting Cells for the Induction of Anterior Chamber-Associated Immune Deviation

Skelsey, M. E., Mayhew, E. & Niederkorn, J. Y., Dec 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 12, p. 5242-5251 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

The immune privilege of corneal grafts

Niederkorn, J. Y., Aug 1 2003, In : Journal of Leukocyte Biology. 74, 2, p. 167-171 5 p.

Research output: Contribution to journalReview article

87 Scopus citations

The interaction of Acanthamoeba castellanii cysts with macrophages and neutrophils

Hurt, M., Proy, V., Niederkorn, J. Y. & Alizadeh, H., Jun 2003, In : Journal of Parasitology. 89, 3, p. 565-572 8 p.

Research output: Contribution to journalArticle

27 Scopus citations
2002

Adaptive immune responses to Acanthamoeba cysts

McClellan, K., Howard, K., Mayhew, E., Niederkorn, J. Y. & Alizadeh, H., Jan 1 2002, In : Experimental Eye Research. 75, 3, p. 285-293 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Effect of alloantibodies on corneal allograft survival

Hegde, S., Mellon, J. K., Hargrave, S. L. & Niederkorn, J. Y., Apr 9 2002, In : Investigative Ophthalmology and Visual Science. 43, 4, p. 1012-1018 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Immune privilege in the anterior chamber of the eye

Niederkorn, J. Y., Aug 15 2002, In : Critical Reviews in Immunology. 22, 1, p. 13-46 34 p.

Research output: Contribution to journalReview article

119 Scopus citations

Immunology and immunomodulation of corneal transplantation

Niederkorn, J. Y., Aug 1 2002, In : International Reviews of Immunology. 21, 2-3, p. 173-196 24 p.

Research output: Contribution to journalReview article

72 Scopus citations

MHC matching improves corneal allograft survival in mice with Th2-immune bias

Hargrave, S. L., Mellon, J. & Niederkorn, J., Dec 1 2002, In : Transplantation proceedings. 34, 8, p. 3413-3415 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Phenotypic analysis of oral tolerance to alloantigens: Evidence that the indirect pathway of antigen presentation is involved

Niederkorn, J. Y. & Mayhew, E., May 15 2002, In : Transplantation. 73, 9, p. 1493-1500 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Resistance of Acanthamoeba castellanii cysts to physical, chemical, and radiological conditions

Aksozek, A., McClellan, K., Howard, K., Niederkorn, J. Y. & Alizadeh, H., 2002, In : Journal of Parasitology. 88, 3, p. 621-623 3 p.

Research output: Contribution to journalArticle

113 Scopus citations

Role of tear anti-Acanthamoeba IgA in Acanthamoeba keratitis

Niederkorn, J. Y., Alizadeh, H., Leher, H., Apte, S., El Agha, S., Ling, L., Hurt, M., Howard, K., Cavanagh, H. D. & McCulley, J. P., Dec 1 2002, In : Advances in experimental medicine and biology. 506 B, p. 845-850 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

The Role of the Innate and Adaptive Immune Responses in Acanthamoeba Keratitis

Niederkorn, J. Y., Dec 1 2002, In : Archivum Immunologiae et Therapiae Experimentalis. 50, 1, p. 53-59 7 p.

Research output: Contribution to journalReview article

24 Scopus citations
2001

Angiostatin produced by certain primary uveal melanoma cell lines impedes the development of liver metastases

Apte, R. S., Niederkorn, J. Y., Mayhew, E. & Alizadeh, H., Dec 2001, In : Archives of Ophthalmology. 119, 12, p. 1805-1809 5 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Effect of steroids on Acanthamoeba cysts and trophozoites

McClellan, K., Howard, K., Niederkorn, J. Y. & Alizadeh, H., Nov 17 2001, In : Investigative Ophthalmology and Visual Science. 42, 12, p. 2885-2893 9 p.

Research output: Contribution to journalArticle

84 Scopus citations

Exacerbation of acanthamoeba keratitis in animals treated with anti-macrophage inflammatory protein 2 or antineutrophil antibodies

Hurt, M., Apte, S., Leher, H., Howard, K., Niederkorn, J. & Alizadeh, H., May 2 2001, In : Infection and immunity. 69, 5, p. 2988-2995 8 p.

Research output: Contribution to journalArticle

46 Scopus citations
45 Scopus citations

Ocular immune privilege promoted by the presentation of peptide on tolerogenic B cells in the spleen. II. Evidence for presentation by Qa-11

D'Orazio, T. J., Mayhew, E. & Niederkorn, J. Y., Jan 1 2001, In : Journal of Immunology. 166, 1, p. 26-32 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Role of Fas ligand in uveal melanoma-induced liver damage

Repp, A. C., Mayhew, E. S., Howard, K., Alizadeh, H. & Niederkorn, J. Y., Jan 1 2001, In : Graefe's Archive for Clinical and Experimental Ophthalmology. 239, 10, p. 752-758 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Tear IgA and serum IgG antibodies against Acanthamoeba in patients with Acanthamoeba keratitis

Alizadeh, H., Apte, S., El-Agha, M. S. H., Li, L., Hurt, M., Howard, K., Cavanagh, H. D., McCulley, J. P. & Niederkorn, J. Y., Aug 14 2001, In : Cornea. 20, 6, p. 622-627 6 p.

Research output: Contribution to journalArticle

60 Scopus citations

γδ T cells are needed for ocular immune privilege and corneal graft survival

Skelsey, M. E., Mellon, J. & Niederkorn, J. Y., Apr 1 2001, In : Journal of Immunology. 166, 7, p. 4327-4333 7 p.

Research output: Contribution to journalArticle

89 Scopus citations
2000

High-risk corneal allografts are capable of stimulating complement dependent cytolytic antibodies

Hargrave, S. L., Taherzadeh, S., Hegde, S. & Niederkorn, J., Jul 1 2000, In : Cornea. 19, 4, p. 521-525 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Human uveal melanoma cells produce macrophage migration-inhibitory factor to prevent lysis by NK cells

Repp, A. C., Mayhew, E. S., Apte, S. & Niederkorn, J. Y., Jul 15 2000, In : Journal of Immunology. 165, 2, p. 710-715 6 p.

Research output: Contribution to journalArticle

Open Access
99 Scopus citations

The diagnosis and management of Acanthamoeba keratitis

McCulley, J. P., Alizadeh, H. & Niederkorn, J. Y., Jan 1 2000, In : CLAO Journal. 26, 1, p. 47-51 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

The role of cytotoxic T lymphocytes in corneal allograft rejection

Hegde, S. & Niederkorn, J. Y., Jan 1 2000, In : Investigative Ophthalmology and Visual Science. 41, 11, p. 3341-3347 7 p.

Research output: Contribution to journalArticle

54 Scopus citations