• 11409 Citations
  • 57 h-Index
1977 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

1999

Anterior chamber-associated immune deviation

Niederkorn, J. Y., Oct 28 1999, In : Chemical Immunology. 73, p. 59-71 13 p.

Research output: Contribution to journalReview article

27 Scopus citations

Effect of aqueous humor on apoptosis of inflammatory cell types

D'Orazio, T. J., DeMarco, B. M., Mayhew, E. S. & Niederkorn, J. Y., Jun 9 1999, In : Investigative Ophthalmology and Visual Science. 40, 7, p. 1418-1426 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Expression of a nonclassical MHC class Ib molecule in the eye

Niederkorn, J. Y., Chiang, E. Y., Ungchusri, T. & Stroynowski, I., Dec 15 1999, In : Transplantation. 68, 11, p. 1790-1799 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Inhibition of intraocular tumor growth by topical application of the angiostatic steroid anecortave acetate

Clark, A. F., Mellon, J., Li, X. Y., Ma, D., Leher, H., Apte, R., Alizadeh, H., Hegde, S., McLenaghan, A., Mayhew, E., D'Orazio, T. J. & Niederkorn, J. Y., Aug 1 1999, In : Investigative Ophthalmology and Visual Science. 40, 9, p. 2158-2162 5 p.

Research output: Contribution to journalArticle

65 Scopus citations

Monoclonal IgA antibodies protect against Acanthamoeba keratitis

Leher, H., Zaragoza, F., Taherzadeh, S., Alizadeh, H. & Niederkorn, J. Y., Jul 1999, In : Experimental Eye Research. 69, 1, p. 75-84 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

The immune privilege of corneal allografts

Niederkorn, J. Y., Jun 27 1999, In : Transplantation. 67, 12, p. 1503-1508 6 p.

Research output: Contribution to journalArticle

145 Scopus citations

The immunobiology of Acanthamoeba keratitis

Niederkorn, J. Y., Alizadeh, H., Leher, H. F. & McCulley, J. P., Aug 6 1999, In : Springer Seminars in Immunopathology. 21, 2, p. 147-160 14 p.

Research output: Contribution to journalReview article

30 Scopus citations

The immunology of corneal transplantation.

Niederkorn, J. Y., 1999, In : Developments in ophthalmology. 30, p. 129-140 12 p.

Research output: Contribution to journalReview article

26 Scopus citations

The pathogenesis of Acanthamoeba keratitis

Niederkorn, J. Y., Alizadeh, H., Leher, H. & McCulley, J. P., May 1999, In : Microbes and Infection. 1, 6, p. 437-443 7 p.

Research output: Contribution to journalArticle

132 Scopus citations
1998

A novel role for TGF-β and IL-10 in the induction of immune privilege

D'Orazio, T. J. & Niederkorn, J. Y., Mar 1 1998, In : Journal of Immunology. 160, 5, p. 2089-2098 10 p.

Research output: Contribution to journalArticle

238 Scopus citations

Aqueous humor-borne factor upregulates Bcl-2 expression in corneal endothelial cells

Li, X. Y., De Marco, B. M., Mayhew, E. S. & Niederkorn, J. Y., Oct 23 1998, In : Current Eye Research. 17, 10, p. 970-978 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Cutting edge: Role of macrophage migration inhibitory factor in inhibiting NK cell activity and preserving immune privilege

Apte, R. S., Sinha, D., Mayhew, E., Wistow, G. J. & Niederkorn, J. Y., Jun 15 1998, In : Journal of Immunology. 160, 12, p. 5693-5696 4 p.

Research output: Contribution to journalArticle

205 Scopus citations

Immunologic phenotype of hosts orally immunized with corneal alloantigens

Ma, D., Li, X. Y., Mellon, J. & Niederkorn, J. Y., Apr 1998, In : Investigative Ophthalmology and Visual Science. 39, 5, p. 744-753 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Impact of oral immunization with Acanthamoeba antigens on parasite adhesion and corneal infection

Leher, H., Kinoshita, K., Alizadeh, H., Zaragoza, F. L., He, Y. & Niederkorn, J., Nov 1 1998, In : Investigative Ophthalmology and Visual Science. 39, 12, p. 2337-2343 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Mannose induces the release of cytopathic factors from Acanthamoeba castellanii

Leher, H., Silvany, R., Alizadeh, H., Huang, J. & Niederkorn, J. Y., Jan 13 1998, In : Infection and immunity. 66, 1, p. 5-10 6 p.

Research output: Contribution to journalArticle

72 Scopus citations

Role of epidermal growth factor receptor in the metastasis of intraocular melanomas

Ma, D. & Niederkorn, J. Y., Jun 1 1998, In : Investigative Ophthalmology and Visual Science. 39, 7, p. 1067-1075 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Role of mucosal IgA in the resistance to Acanthamoeba keratitis

Leher, H. F., Alizadeh, H., Taylor, W. M., Shea, A. S., Silvany, R. S., Van Klink, F., Jager, M. J. & Niederkorn, J. Y., Dec 1 1998, In : Investigative Ophthalmology and Visual Science. 39, 13, p. 2666-2673 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Splenic B cells are required for tolerogenic antigen presentation in the induction of anterior chamber-associated immune deviation (ACAID)

D'Orazio, T. J. & Niederkorn, J. Y., Sep 15 1998, In : Immunology. 95, 1, p. 47-55 9 p.

Research output: Contribution to journalArticle

76 Scopus citations

The nature of antigen in the eye has a profound effect on the cytokine milieu and resultant immune response

D'Orazio, T. J. & Niederkorn, J. Y., May 1 1998, In : European Journal of Immunology. 28, 5, p. 1544-1553 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
1997

Effect of hyperthermia on expression of histocompatibility antigens and heat-shock protein molecules on three human ocular melanoma cell lines

Blom, D. J. R., De Waard-Siebinga, I., Apte, R. S., Luyten, G. P. M., Niederkorn, J. Y. & Jager, M. J., Jan 1 1997, In : Melanoma research. 7, 2, p. 103-109 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Immune privilege in the anterior chamber of the eye is not extended to intraocular Listeria monocytogenes

Li, X. Y. & Niederkorn, J. Y., Jan 1 1997, In : Ocular Immunology and Inflammation. 5, 4, p. 245-258 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

Immunological analysis of orally induced tolerance to corneal alloantigens

Niederkorn, J. Y., Li, X. Y., Ma, D. & Mellon, J., Dec 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 4, p. S9

Research output: Contribution to journalArticle

Immunoregulation of intraocular tumours

Niederkorn, J. Y., Jan 1 1997, In : Eye. 11, 2, p. 249-254 6 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

Inhibition of metastasis of intraocular melanomas by adenovirus-mediated gene transfer of plasminogen activator inhibitor type I (PAI-1) in an athymic mouse model

Ma, D., Gerard, R. D., Li, X. Y., Alizadeh, H. & Niederkorn, J. Y., Oct 1 1997, In : Blood. 90, 7, p. 2738-2746 9 p.

Research output: Contribution to journalArticle

Open Access
74 Scopus citations

Local inhibition of natural killer cell activity promotes the progressive growth of intraocular tumors

Apte, R. S., Mayhew, E. & Niederkorn, J. Y., Jun 11 1997, In : Investigative Ophthalmology and Visual Science. 38, 6, p. 1277-1282 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Oral immunisation as a strategy for enhancing corneal allograft survival

Ma, D., Mellon, J. & Niederkorn, J. Y., Sep 1997, In : British Journal of Ophthalmology. 81, 9, p. 778-784 7 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations

Susceptibilty of murine corneal kpithklial and endothelial cells to lysis by complement-dependent alloantibody

Hargrave, S. L., Mayhem, E. S., Hedge, S. & Niederkorn, J. Y., Dec 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 4, p. S9

Research output: Contribution to journalArticle

2 Scopus citations

Systemic immune response to Acanthamoeba keratitis in the Chinese hamster

Van Klink, F., Leher, H., Jager, M. J., Alizadeh, H., Taylor, W. & Niederkorn, J. Y., Dec 1 1997, In : Ocular Immunology and Inflammation. 5, 4, p. 235-244 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

The generation of regulatory t cells in an in vitro model of the acaid spleen

D'Orazio, T. J. & Niederkorn, J. Y., Dec 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 4, p. S492

Research output: Contribution to journalArticle

1996

Acanthamoeba keratitis primes humoral but not cellular immune responses

Leher, H. F., Alizadeh, H. & Niederkorn, J. Y., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3, p. S416

Research output: Contribution to journalArticle

Anterior chamber-associated immune deviation promotes corneal allograft survival

Niederkorn, J. Y. & Mellon, J., Dec 1 1996, In : Investigative Ophthalmology and Visual Science. 37, 13, p. 2700-2707 8 p.

Research output: Contribution to journalArticle

106 Scopus citations

Association between NM23-H1 gene expression and metastasis of human uveal melanoma in an animal model

Ma, D., Luyten, G. P., Luider, T. M., Jager, M. J. & Niederkorn, J. Y., Oct 1 1996, In : Investigative Ophthalmology and Visual Science. 37, 11, p. 2293-2301 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Depletion of donor-derived Langerhans cells promotes corneal allograft survival

He, Y. G. & Niederkorn, J. Y., 1996, In : Cornea. 15, 1, p. 82-89 8 p.

Research output: Contribution to journalArticle

59 Scopus citations

Effect of cholesterol on the growth and virulence of Acanthamoeba castellanii

Mitra, M. M., Silvany, R. E., Leher, H. F., Alizadeh, H. & Niederkorn, J. Y., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3, p. S871

Research output: Contribution to journalArticle

Effect of transforming growth factor-beta on plasminogen activator production of cultured human uveal melanoma cells

Park, S. S., Li, L., Korn, T. S., Mitra, M. M. & Niederkorn, J. Y., Jan 1 1996, In : Current Eye Research. 15, 7, p. 755-763 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Gene therapy for preventing the metastasis of intraocular melanoma

Niederkorn, J. Y., Ma, D., Li, X. Y. & Gerard, R. D., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3, p. S1114

Research output: Contribution to journalArticle

Isolation and characterization of a unique natural killer cell inhibitory factor present in the anterior chamber of the eye

Apte, R. S. & Niederkorn, J. Y., Apr 15 1996, In : Journal of Immunology. 156, 8, p. 2667-2673 7 p.

Research output: Contribution to journalArticle

80 Scopus citations

Protective immunity against Acanthahoeba keratitis in a Chinese hamster model

Alizadeh, H., Taylor, W., Haehling, E., Stewart, G. L., Van Klink, F., McCulley, J. P. & Niederkorn, J. Y., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3, p. S871

Research output: Contribution to journalArticle

Role of macrophages in Acanthamoeba keratitis

Van Klink, F., Taylor, W. M., Alizadeh, H., Jager, M. J., Van Rooijen, N. & Niederkorn, J. Y., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3, p. S416

Research output: Contribution to journalArticle

24 Scopus citations

Role of Th1 and Th2 cells in anterior chamber-associated immune deviation

Li, X. Y., D'Orazio, T. & Niederkorn, J. Y., Jan 1 1996, In : Immunology. 89, 1, p. 34-40 7 p.

Research output: Contribution to journalArticle

61 Scopus citations

The effect of oral immunization on corneal allograft survival

He, Y. G., Mellon, J. & Niederkorn, J. Y., Mar 27 1996, In : Transplantation. 61, 6, p. 920-926 7 p.

Research output: Contribution to journalArticle

52 Scopus citations

The role of macrophages in Acanthamoeba keratitis

Van Klink, F., Taylor, W. M., Alizadeh, H., Jager, M. J., Van Rooijen, N. & Niederkorn, J. Y., Jun 1 1996, In : Investigative Ophthalmology and Visual Science. 37, 7, p. 1271-1281 11 p.

Research output: Contribution to journalArticle

57 Scopus citations
1995

Acanthamoeba keratitis

McCulley, J. P., Alizadeh, H. & Niederkorn, J. Y., Jan 1 1995, In : CLAO Journal. 21, 1, p. 73-76 4 p.

Research output: Contribution to journalArticle

40 Scopus citations
15 Scopus citations

Anti-leukocyte function-1 antibody treatment prevents the rejection of intraocular regressor tumors and their metastases

Li, X. Y., Mayhew, E. & Niederkorn, J. Y., Jan 1 1995, In : Current Eye Research. 14, 8, p. 719-726 8 p.

Research output: Contribution to journalArticle

2 Scopus citations